Motif ID: RFX1..5_RFXANK_RFXAP.p2

Z-value: 1.555


Transcription factors associated with RFX1..5_RFXANK_RFXAP.p2:

Gene SymbolEntrez IDGene Name
RFX1 5989 regulatory factor X, 1 (influences HLA class II expression)
RFX2 5990 regulatory factor X, 2 (influences HLA class II expression)
RFX3 5991 regulatory factor X, 3 (influences HLA class II expression)
RFX4 5992 regulatory factor X, 4 (influences HLA class II expression)
RFX5 5993 regulatory factor X, 5 (influences HLA class II expression)
RFXANK 8625 regulatory factor X-associated ankyrin-containing protein
RFXAP 5994 regulatory factor X-associated protein

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
RFX2chr19_-_60614910.775.1e-04Click!
RFX4chr12_+_1055190490.533.5e-02Click!
RFX3chr9_-_3515973-0.467.2e-02Click!
RFXANKchr19_+_191646490.342.0e-01Click!
RFX5chr1_-_1495863410.253.5e-01Click!
RFXAPchr13_+_36291306-0.233.9e-01Click!
RFX1chr19_-_139778750.204.7e-01Click!


Activity profile for motif RFX1..5_RFXANK_RFXAP.p2.

activity profile for motif RFX1..5_RFXANK_RFXAP.p2


Sorted Z-values histogram for motif RFX1..5_RFXANK_RFXAP.p2

Sorted Z-values for motif RFX1..5_RFXANK_RFXAP.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of RFX1..5_RFXANK_RFXAP.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr17_-_61618276 2.369 NM_145036
 CCDC46
coiled-coil domain containing 46
chr2_-_187422141 2.226 NM_182521
 ZSWIM2
zinc finger, SWIM-type containing 2
chr17_-_58239382 2.104 NM_152598
 MARCH10
membrane-associated ring finger (C3HC4) 10
chr11_+_93885342 1.812 NM_001190462
 LOC643037
hypothetical protein LOC643037
chr2_+_27046952 1.651 NM_012326
 MAPRE3
microtubule-associated protein, RP/EB family, member 3
chr1_-_33669190 1.430 PHC2
polyhomeotic homolog 2 (Drosophila)
chr14_-_88087575 1.395 PTPN21
protein tyrosine phosphatase, non-receptor type 21
chr13_-_95092283 1.381 DZIP1
DAZ interacting protein 1
chr5_-_149649593 1.349 NM_015981
NM_171825
 CAMK2A

calcium/calmodulin-dependent protein kinase II alpha

chr5_+_92944680 1.332 NM_005654
 NR2F1
nuclear receptor subfamily 2, group F, member 1
chr3_-_139315011 1.307 NM_001170538
 DZIP1L
DAZ interacting protein 1-like
chr11_+_110890719 1.283 NM_001100388
NM_207430
 C11orf88

chromosome 11 open reading frame 88

chr6_+_109276280 1.277 NM_032131
 ARMC2
armadillo repeat containing 2
chrX_-_48578878 1.246 NM_013271
 PCSK1N
proprotein convertase subtilisin/kexin type 1 inhibitor
chr1_+_42701460 1.191 CCDC30
coiled-coil domain containing 30
chr19_-_51666503 1.142 PNMAL1
PNMA-like 1
chr10_-_116382089 1.129 ABLIM1
actin binding LIM protein 1
chr5_-_54565181 1.121 NM_021147
 CCNO
cyclin O
chr16_-_65984836 1.077 NM_015964
NM_016140
 TPPP3

tubulin polymerization-promoting protein family member 3

chr19_-_51690989 1.071 NM_020709
 PNMAL2
PNMA-like 2

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

Showing 1 to 6 of 6 entries
enrichment   p-value GO term description
6.31 2.49e-04 GO:0035085 cilium axoneme
5.38 1.86e-04 GO:0005930 axoneme
4.90 5.76e-04 GO:0044441 cilium part
3.63 1.44e-05 GO:0005929 cilium
2.40 7.97e-03 GO:0005874 microtubule
1.20 1.70e-04 GO:0005737 cytoplasm

Gene overrepresentation in function category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
1.55 7.88e-04 GO:0017076 purine nucleotide binding
1.53 1.78e-03 GO:0032553 ribonucleotide binding
1.53 1.78e-03 GO:0032555 purine ribonucleotide binding
1.53 1.82e-02 GO:0030554 adenyl nucleotide binding
1.52 4.13e-03 GO:0035639 purine ribonucleoside triphosphate binding
1.52 2.49e-02 GO:0032559 adenyl ribonucleotide binding
1.44 8.20e-03 GO:0000166 nucleotide binding