Motif ID: RREB1.p2

Z-value: 6.538


Transcription factors associated with RREB1.p2:

Gene SymbolEntrez IDGene Name
RREB1 6239 ras responsive element binding protein 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
RREB1chr6_+_70538630.273.1e-01Click!


Activity profile for motif RREB1.p2.

activity profile for motif RREB1.p2


Sorted Z-values histogram for motif RREB1.p2

Sorted Z-values for motif RREB1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of RREB1.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_+_17665483 13.561 NM_001037535
NM_001037536
NM_001037540
NM_006746
SCML1



sex comb on midleg-like 1 (Drosophila)



chr16_-_3225360 12.899 NM_001145448
NM_198088
NM_001145446
NM_198087
ZNF200



zinc finger protein 200



chr19_-_55914837 11.438


chr4_-_809879 10.971 NM_006651
CPLX1
complexin 1
chr20_+_55359551 10.379 NM_003610
RAE1
RAE1 RNA export 1 homolog (S. pombe)
chr3_+_187917791 9.860 NM_000893
NM_001102416
NM_001166451
KNG1


kininogen 1


chr20_+_55359706 9.809 RAE1
RAE1 RNA export 1 homolog (S. pombe)
chr21_+_42946719 9.569 NM_001001567
NM_001001568
NM_001001569
NM_001001570
NM_001001571
NM_001001572
NM_001001573
NM_001001574
NM_001001575
NM_001001576
NM_001001577
NM_001001578
NM_001001579
NM_001001580
NM_001001581
NM_001001582
NM_001001583
NM_001001584
NM_001001585
NM_002606
PDE9A



















phosphodiesterase 9A



















chr16_-_3225070 9.377 NM_001145447
NM_003454
ZNF200

zinc finger protein 200

chr19_-_51168396 8.656 NM_002516
NOVA2
neuro-oncological ventral antigen 2
chr11_-_133786935 8.085 NM_018644
NM_054025
B3GAT1

beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)

chr7_+_44110527 7.829 AEBP1
AE binding protein 1
chr7_+_44110470 7.677 NM_001129
AEBP1
AE binding protein 1
chr4_-_46086528 7.496 NM_000807
GABRA2
gamma-aminobutyric acid (GABA) A receptor, alpha 2
chr16_+_86193993 6.947 NM_020655
JPH3
junctophilin 3
chr1_-_202647526 6.922 NM_032833
PPP1R15B
protein phosphatase 1, regulatory (inhibitor) subunit 15B
chr19_+_3317589 6.829 NFIC
nuclear factor I/C (CCAAT-binding transcription factor)
chr22_+_48966394 6.812 TRABD
TraB domain containing
chr4_+_191235959 6.684 NM_001177376
DUX4L4
double homeobox 4 like 4
chr22_+_48966480 6.654 NM_025204
TRABD
TraB domain containing
chr17_+_77582774 6.412 NM_005052
RAC3
ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
chr5_+_78943998 6.383 NM_001114393
NM_001114394
NM_173797
PAPD4


PAP associated domain containing 4


chr3_+_12304332 6.115 NM_005037
NM_138712
PPARG

peroxisome proliferator-activated receptor gamma

chr5_+_78944052 6.090 PAPD4
PAP associated domain containing 4
chr12_+_6807831 5.997 NM_014262
LEPREL2
leprecan-like 2
chr19_+_540849 5.932 NM_001194
HCN2
hyperpolarization activated cyclic nucleotide-gated potassium channel 2
chr2_+_42128521 5.882 NM_138370
PKDCC
protein kinase domain containing, cytoplasmic homolog (mouse)
chrX_-_119133802 5.582 NM_139282
RHOXF1
Rhox homeobox family, member 1
chr5_+_78944151 5.450 PAPD4
PAP associated domain containing 4
chr1_-_154318412 5.414 NM_001093725
MEX3A
mex-3 homolog A (C. elegans)
chr14_-_64638809 5.327 MAX
MYC associated factor X
chr20_-_47618059 5.211 NM_000961
PTGIS
prostaglandin I2 (prostacyclin) synthase
chr19_+_3317575 5.199 NFIC
nuclear factor I/C (CCAAT-binding transcription factor)
chr2_-_163403274 5.151 KCNH7
potassium voltage-gated channel, subfamily H (eag-related), member 7
chr4_+_191245840 4.961 NM_033178
NM_012147
NM_001177376
NM_001127388
NM_001127389
NM_001164467
NM_001127386
DUX4
DUX2
DUX4L4
DUX4L6
DUX4L5
DUX4L3
DUX4L2
double homeobox 4
double homeobox 2
double homeobox 4 like 4
double homeobox 4 like 6
double homeobox 4 like 5
double homeobox 4 like 3
double homeobox 4 like 2
chr13_-_107665871 4.928 NM_206937
LIG4
ligase IV, DNA, ATP-dependent
chr22_-_41913002 4.875 TTLL12
tubulin tyrosine ligase-like family, member 12
chr4_+_191232653 4.779 NM_033178
NM_012147
NM_001177376
NM_001127387
NM_001127388
NM_001127389
NM_001164467
NM_001127386
DUX4
DUX2
DUX4L4
DUX4L7
DUX4L6
DUX4L5
DUX4L3
DUX4L2
double homeobox 4
double homeobox 2
double homeobox 4 like 4
double homeobox 4 like 7
double homeobox 4 like 6
double homeobox 4 like 5
double homeobox 4 like 3
double homeobox 4 like 2
chr16_+_28741873 4.748 ATXN2L
ataxin 2-like
chrX_+_53095230 4.641 NM_018969
GPR173
G protein-coupled receptor 173
chr12_-_53071285 4.630 NM_001130967
NM_001130968
ZNF385A

zinc finger protein 385A

chrX_-_101658297 4.522 NM_021992
TMSB15A
TMSB15B
thymosin beta 15a
thymosin beta 15B
chr2_+_5750229 4.450 NM_003108
SOX11
SRY (sex determining region Y)-box 11
chr16_+_28741908 4.398 NM_007245
NM_145714
NM_148414
NM_148415
NM_148416
ATXN2L




ataxin 2-like




chr16_+_28741861 4.369 ATXN2L
ataxin 2-like
chr19_+_4442610 4.333 HDGFRP2
hepatoma-derived growth factor-related protein 2
chr19_+_3317536 4.315 NM_005597
NFIC
nuclear factor I/C (CCAAT-binding transcription factor)
chr22_-_30929463 4.309 NM_001098527
RFPL2
ret finger protein-like 2
chr22_-_41913076 4.293 NM_015140
TTLL12
tubulin tyrosine ligase-like family, member 12
chr21_-_43368963 4.249 NM_000071
CBS
cystathionine-beta-synthase
chrX_-_1291526 4.073 NM_001012288
NM_022148
CRLF2

cytokine receptor-like factor 2

chr22_-_41913075 4.064 TTLL12
tubulin tyrosine ligase-like family, member 12
chr11_+_65311104 4.004 NM_004561
OVOL1
ovo-like 1(Drosophila)
chr21_-_43369492 3.994 NM_001178008
NM_001178009
CBS

cystathionine-beta-synthase

chr7_+_65731364 3.993 KCTD7
potassium channel tetramerisation domain containing 7
chr3_+_171621721 3.956 NM_001185056
CLDN11
claudin 11
chr1_-_148155986 3.954 NM_014849
SV2A
synaptic vesicle glycoprotein 2A
chrX_+_152561086 3.933 NM_001395
DUSP9
dual specificity phosphatase 9
chr20_-_21326046 3.911 NM_033176
NKX2-4
NK2 homeobox 4
chrX_-_151057615 3.906 NM_001011543
NM_021048
MAGEA10

melanoma antigen family A, 10

chr4_+_191226073 3.893 NM_012147
NM_001177376
NM_001127388
NM_001127389
NM_001164467
DUX2
DUX4L4
DUX4L6
DUX4L5
DUX4L3
double homeobox 2
double homeobox 4 like 4
double homeobox 4 like 6
double homeobox 4 like 5
double homeobox 4 like 3
chr19_+_659766 3.852 NM_001040134
NM_002579
PALM

paralemmin

chr4_-_5941043 3.707 CRMP1
collapsin response mediator protein 1
chr10_-_103525646 3.699 NM_006119
NM_033163
NM_033164
NM_033165
FGF8



fibroblast growth factor 8 (androgen-induced)



chr1_-_23623713 3.686 NM_003196
TCEA3
transcription elongation factor A (SII), 3
chr22_+_49459935 3.682 NM_001080420
SHANK3
SH3 and multiple ankyrin repeat domains 3
chr10_+_135333667 3.647 NM_033178
NM_012147
NM_001127387
NM_001127388
NM_001127389
NM_001164467
NM_001127386
DUX4
DUX2
DUX4L7
DUX4L6
DUX4L5
DUX4L3
DUX4L2
double homeobox 4
double homeobox 2
double homeobox 4 like 7
double homeobox 4 like 6
double homeobox 4 like 5
double homeobox 4 like 3
double homeobox 4 like 2
chr16_+_28742066 3.579 ATXN2L
ataxin 2-like
chr17_-_44047299 3.560 NM_024016
HOXB8
homeobox B8
chr11_-_27678551 3.543 NM_001143813
NM_001143814
NM_001709
BDNF


brain-derived neurotrophic factor


chr11_-_76059435 3.529 NM_001128922
LRRC32
leucine rich repeat containing 32
chr4_-_5941167 3.509 NM_001313
CRMP1
collapsin response mediator protein 1
chrX_-_137621492 3.505 NM_004114
FGF13
fibroblast growth factor 13
chr5_+_92946348 3.468 NR2F1
nuclear receptor subfamily 2, group F, member 1
chr1_-_154484341 3.455 NM_198406
NM_024897
PAQR6

progestin and adipoQ receptor family member VI

chr3_+_194441586 3.442 NM_020386
HRASLS
HRAS-like suppressor
chr1_+_1066138 3.441


chr1_+_2975590 3.441 NM_022114
NM_199454
PRDM16

PR domain containing 16

chr11_+_56984702 3.377 NM_178570
RTN4RL2
reticulon 4 receptor-like 2
chr11_+_65311142 3.371 OVOL1
ovo-like 1(Drosophila)
chr14_+_28305922 3.365 NM_005249
FOXG1
forkhead box G1
chr4_+_191242540 3.319 NM_033178
NM_012147
NM_001177376
NM_001127387
NM_001127388
NM_001127389
NM_001164467
NM_001127386
DUX4
DUX2
DUX4L4
DUX4L7
DUX4L6
DUX4L5
DUX4L3
DUX4L2
double homeobox 4
double homeobox 2
double homeobox 4 like 4
double homeobox 4 like 7
double homeobox 4 like 6
double homeobox 4 like 5
double homeobox 4 like 3
double homeobox 4 like 2
chrX_+_153466611 3.311 NM_001327
NM_139250
CTAG1B
CTAG1A
cancer/testis antigen 1B
cancer/testis antigen 1A
chrX_-_48578878 3.303 NM_013271
PCSK1N
proprotein convertase subtilisin/kexin type 1 inhibitor
chr7_-_100331417 3.285 NM_000665
NM_015831
ACHE

acetylcholinesterase

chr19_-_15421761 3.261 NM_021241
WIZ
widely interspaced zinc finger motifs
chr20_-_26137755 3.248 LOC284801
hypothetical protein LOC284801
chr11_+_359723 3.242 NM_178537
B4GALNT4
beta-1,4-N-acetyl-galactosaminyl transferase 4
chr3_-_71715431 3.239 NM_001012505
NM_032682
FOXP1

forkhead box P1

chr10_+_135343649 3.229 NM_012147
DUX2
double homeobox 2
chr16_+_1143241 3.227 NM_001005407
NM_021098
CACNA1H

calcium channel, voltage-dependent, T type, alpha 1H subunit

chr4_+_191239247 3.198 NM_033178
NM_012147
NM_001177376
NM_001127388
NM_001127389
NM_001164467
NM_001127386
DUX4
DUX2
DUX4L4
DUX4L6
DUX4L5
DUX4L3
DUX4L2
double homeobox 4
double homeobox 2
double homeobox 4 like 4
double homeobox 4 like 6
double homeobox 4 like 5
double homeobox 4 like 3
double homeobox 4 like 2
chr20_-_62151216 3.193 NM_018419
SOX18
SRY (sex determining region Y)-box 18
chrX_-_39841599 3.163 NM_001123385
NM_017745
BCOR

BCL6 corepressor

chr1_-_182273114 3.158 GLT25D2
glycosyltransferase 25 domain containing 2
chr13_-_113066202 3.124 GRTP1
growth hormone regulated TBC protein 1
chr21_-_44506526 3.114 NM_013369
NM_175867
DNMT3L

DNA (cytosine-5-)-methyltransferase 3-like

chrX_+_102471769 3.089 NM_152278
TCEAL7
transcription elongation factor A (SII)-like 7
chr19_+_56506907 3.061 NM_001101372
IGLON5
IgLON family member 5
chr2_-_163403485 3.057 NM_033272
NM_173162
KCNH7

potassium voltage-gated channel, subfamily H (eag-related), member 7

chr20_+_48032918 3.054 NM_005985
SNAI1
snail homolog 1 (Drosophila)
chr8_-_41624030 3.036 NM_152568
NKX6-3
NK6 homeobox 3
chr10_+_83625049 3.027 NM_001010848
NM_001165972
NRG3

neuregulin 3

chr16_+_1143738 3.018 CACNA1H
calcium channel, voltage-dependent, T type, alpha 1H subunit
chr19_-_55763091 2.996 NM_001080457
LRRC4B
leucine rich repeat containing 4B
chr11_-_69228286 2.990 NM_005117
FGF19
fibroblast growth factor 19
chr3_-_48607596 2.979 NM_000094
COL7A1
collagen, type VII, alpha 1
chr11_-_8695974 2.970 ST5
suppression of tumorigenicity 5
chr20_-_62071584 2.959 NM_020713
ZNF512B
zinc finger protein 512B
chr10_-_126839000 2.948 CTBP2
C-terminal binding protein 2
chr17_-_60208083 2.931 LOC146880
hypothetical LOC146880
chr4_+_191229360 2.927 NM_033178
NM_012147
NM_001177376
NM_001127387
NM_001127388
NM_001127389
NM_001164467
NM_001127386
DUX4
DUX2
DUX4L4
DUX4L7
DUX4L6
DUX4L5
DUX4L3
DUX4L2
double homeobox 4
double homeobox 2
double homeobox 4 like 4
double homeobox 4 like 7
double homeobox 4 like 6
double homeobox 4 like 5
double homeobox 4 like 3
double homeobox 4 like 2
chr11_-_27679022 2.909 NM_001143812
BDNF
brain-derived neurotrophic factor
chr11_-_76058542 2.904 NM_005512
LRRC32
leucine rich repeat containing 32
chr8_-_125252884 2.895 C8orf78
chromosome 8 open reading frame 78
chr8_+_99508425 2.879 NM_020697
KCNS2
potassium voltage-gated channel, delayed-rectifier, subfamily S, member 2
chr11_-_6633427 2.869 NM_003737
DCHS1
dachsous 1 (Drosophila)
chr2_+_10101081 2.858 NM_003597
NM_001177716
KLF11

Kruppel-like factor 11

chr2_+_235525355 2.850 NM_014521
SH3BP4
SH3-domain binding protein 4
chrX_+_151617900 2.838 NM_005363
NM_175868
MAGEA6

melanoma antigen family A, 6

chr8_-_111056099 2.836 NM_014379
KCNV1
potassium channel, subfamily V, member 1
chr12_+_50686990 2.835 NM_181711
GRASP
GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein
chr9_-_115901157 2.834 NM_138424
KIF12
kinesin family member 12
chr18_+_75261231 2.825 NM_172387
NM_172389
NFATC1

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1

chr12_+_52665196 2.811 NM_017409
HOXC10
homeobox C10
chr17_+_26742903 2.772 RAB11FIP4
RAB11 family interacting protein 4 (class II)
chr15_-_49174107 2.772 TNFAIP8L3
tumor necrosis factor, alpha-induced protein 8-like 3
chr19_-_13478037 2.768 NM_000068
NM_001127221
NM_001127222
NM_001174080
NM_023035
CACNA1A




calcium channel, voltage-dependent, P/Q type, alpha 1A subunit




chr13_-_36392370 2.733 NM_001127217
NM_005905
SMAD9

SMAD family member 9

chr1_+_1940605 2.728 NM_000815
GABRD
gamma-aminobutyric acid (GABA) A receptor, delta
chr19_+_40213431 2.726 NM_001037
NM_199037
SCN1B

sodium channel, voltage-gated, type I, beta

chr4_+_3264509 2.703 RGS12
regulator of G-protein signaling 12
chr15_-_54544531 2.688 NM_018365
MNS1
meiosis-specific nuclear structural 1
chr6_-_48144344 2.681 NM_001013732
NM_207499
C6orf138

chromosome 6 open reading frame 138

chrX_-_131918905 2.661 HS6ST2
heparan sulfate 6-O-sulfotransferase 2
chr19_+_38979502 2.656 NM_001129994
NM_001129995
NM_024076
KCTD15


potassium channel tetramerisation domain containing 15


chr17_-_74361975 2.646 TIMP2
TIMP metallopeptidase inhibitor 2
chr10_+_135330357 2.604 NM_033178
NM_012147
NM_001127387
NM_001127388
NM_001127389
NM_001164467
NM_001127386
DUX4
DUX2
DUX4L7
DUX4L6
DUX4L5
DUX4L3
DUX4L2
double homeobox 4
double homeobox 2
double homeobox 4 like 7
double homeobox 4 like 6
double homeobox 4 like 5
double homeobox 4 like 3
double homeobox 4 like 2
chr12_+_6808025 2.600 LEPREL2
leprecan-like 2
chr10_-_135000358 2.596 CALY
calcyon neuron-specific vesicular protein
chr16_+_86194075 2.588 JPH3
junctophilin 3
chr3_+_213430 2.584 CHL1
cell adhesion molecule with homology to L1CAM (close homolog of L1)
chr16_+_88517187 2.581 NM_006086
TUBB3
tubulin, beta 3
chr15_+_22644448 2.577


chr15_-_43267139 2.576 SHF
Src homology 2 domain containing F
chrX_-_152139267 2.574 NM_004988
MAGEA1
melanoma antigen family A, 1 (directs expression of antigen MZ2-E)
chr3_-_41978464 2.569 NM_017886
ULK4
unc-51-like kinase 4 (C. elegans)
chrX_-_135161185 2.569 NM_001173517
NM_024597
MAP7D3

MAP7 domain containing 3

chr1_+_154318954 2.564 LMNA
lamin A/C
chr2_-_219881937 2.564 PTPRN
protein tyrosine phosphatase, receptor type, N
chr5_+_128823904 2.562 NM_133638
ADAMTS19
ADAM metallopeptidase with thrombospondin type 1 motif, 19
chrX_-_148476903 2.547 NM_005365
NM_001080790
MAGEA9
MAGEA9B
melanoma antigen family A, 9
melanoma antigen family A, 9B
chr12_-_21818881 2.537 NM_004982
KCNJ8
potassium inwardly-rectifying channel, subfamily J, member 8
chr15_-_72952648 2.508 NM_005697
SCAMP2
secretory carrier membrane protein 2
chr3_+_213535 2.502 NM_006614
CHL1
cell adhesion molecule with homology to L1CAM (close homolog of L1)
chr19_+_3831675 2.498 ATCAY
ataxia, cerebellar, Cayman type
chr5_-_136862130 2.498 SPOCK1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
chrX_-_151688850 2.489 NM_005362
MAGEA3
melanoma antigen family A, 3
chrX_+_113724806 2.469 NM_000868
HTR2C
5-hydroxytryptamine (serotonin) receptor 2C
chr22_+_47350781 2.435 NM_015381
FAM19A5
family with sequence similarity 19 (chemokine (C-C motif)-like), member A5
chr11_-_88864061 2.427 NM_001143836
NM_016931
NOX4

NADPH oxidase 4

chr14_-_20563698 2.425 NDRG2
NDRG family member 2
chrX_+_128501862 2.424 NM_000276
NM_001587
OCRL

oculocerebrorenal syndrome of Lowe

chr2_+_242679507 2.420 LOC728323
hypothetical LOC728323
chrX_+_148671394 2.415 NM_005365
NM_001080790
MAGEA9
MAGEA9B
melanoma antigen family A, 9
melanoma antigen family A, 9B
chr3_-_159306214 2.411


chr7_-_526005 2.404 NM_002607
NM_033023
PDGFA

platelet-derived growth factor alpha polypeptide

chr3_+_112273352 2.402 PVRL3
poliovirus receptor-related 3
chr14_+_102458745 2.397 NM_030943
AMN
amnionless homolog (mouse)
chr11_-_118799058 2.384 THY1
Thy-1 cell surface antigen
chr6_+_12120709 2.380 NM_002114
HIVEP1
human immunodeficiency virus type I enhancer binding protein 1
chr14_+_68796621 2.376 GALNTL1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 1
chr12_-_47679176 2.364 NM_015086
DDN
dendrin
chr3_+_50629593 2.358 MAPKAPK3
mitogen-activated protein kinase-activated protein kinase 3
chr1_-_75854281 2.358 SLC44A5
solute carrier family 44, member 5
chr13_-_107665130 2.348 NM_002312
LIG4
ligase IV, DNA, ATP-dependent
chr10_-_64248932 2.346 NM_001136178
EGR2
early growth response 2
chr16_+_68516401 2.331 NM_199424
WWP2
WW domain containing E3 ubiquitin protein ligase 2
chr14_-_20563722 2.327 NM_016250
NM_201535
NM_201536
NM_201537
NDRG2



NDRG family member 2



chr17_+_58908152 2.324 NM_000789
ACE
angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
chr8_-_145530639 2.321 NM_031309
SCRT1
scratch homolog 1, zinc finger protein (Drosophila)
chr7_-_127833231 2.294 NM_001142573
NM_001142574
NM_001142575
IMPDH1


IMP (inosine 5'-monophosphate) dehydrogenase 1


chr12_+_50271283 2.289 NM_014191
SCN8A
sodium channel, voltage gated, type VIII, alpha subunit
chr11_-_2115077 2.284


chr3_-_116348780 2.283 NM_015642
ZBTB20
zinc finger and BTB domain containing 20
chr7_-_150129295 2.265 NM_014020
TMEM176B
transmembrane protein 176B
chr17_-_34014390 2.254 SRCIN1
SRC kinase signaling inhibitor 1
chrX_-_71442488 2.245 NM_001144885
NM_001144887
CITED1

Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1

chr3_+_50629604 2.243 NM_004635
MAPKAPK3
mitogen-activated protein kinase-activated protein kinase 3
chr7_+_65731289 2.238 NM_001167961
NM_153033
KCTD7

potassium channel tetramerisation domain containing 7

chrX_-_47394937 2.237 NM_001114123
NM_005229
ELK1

ELK1, member of ETS oncogene family

chr19_+_522260 2.217 NM_198591
BSG
basigin (Ok blood group)
chr17_+_75366524 2.199 NM_005189
NM_032647
CBX2

chromobox homolog 2

chrX_+_151975518 2.194 PNMA3
paraneoplastic antigen MA3
chr14_-_64638974 2.187 NM_002382
NM_145112
NM_145113
NM_145114
NM_145116
NM_197957
MAX





MYC associated factor X





chr19_-_15204767 2.185 NM_001142886
EPHX3
epoxide hydrolase 3
chr11_-_29995063 2.181 NM_002233
KCNA4
potassium voltage-gated channel, shaker-related subfamily, member 4
chr17_-_77474597 2.172 NM_032711
MAFG
v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)
chr3_+_129355006 2.171 EEFSEC
eukaryotic elongation factor, selenocysteine-tRNA-specific
chr15_-_86600658 2.166 NM_001007156
NM_001012338
NM_002530
NTRK3


neurotrophic tyrosine kinase, receptor, type 3



Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.72 2.26e-32 GO:0007399 nervous system development
1.41 2.85e-22 GO:0048731 system development
1.34 9.17e-22 GO:0032502 developmental process
1.35 2.17e-21 GO:0007275 multicellular organismal development
1.37 2.87e-21 GO:0048856 anatomical structure development
1.76 2.45e-19 GO:0048699 generation of neurons
1.74 2.48e-19 GO:0022008 neurogenesis
1.18 2.60e-19 GO:0065007 biological regulation
1.54 4.63e-18 GO:0009653 anatomical structure morphogenesis
1.82 7.59e-18 GO:0030182 neuron differentiation
1.70 1.50e-17 GO:0048468 cell development
1.18 9.70e-17 GO:0050789 regulation of biological process
1.43 2.28e-16 GO:0030154 cell differentiation
1.93 5.10e-16 GO:0007417 central nervous system development
1.19 5.10e-16 GO:0050794 regulation of cellular process
1.42 5.73e-16 GO:0048869 cellular developmental process
1.76 1.45e-12 GO:0009887 organ morphogenesis
1.31 6.91e-12 GO:0048518 positive regulation of biological process
1.56 1.18e-11 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.74 1.68e-11 GO:0048666 neuron development
1.38 4.05e-11 GO:0048513 organ development
1.66 7.63e-11 GO:0045595 regulation of cell differentiation
1.78 8.01e-11 GO:0000904 cell morphogenesis involved in differentiation
1.20 8.12e-11 GO:0032501 multicellular organismal process
1.92 1.14e-10 GO:0007420 brain development
1.30 1.41e-10 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.29 1.86e-10 GO:0051171 regulation of nitrogen compound metabolic process
1.77 3.18e-10 GO:0031175 neuron projection development
1.31 4.58e-10 GO:0048522 positive regulation of cellular process
1.77 6.33e-10 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.79 7.66e-10 GO:0048812 neuron projection morphogenesis
1.80 8.81e-10 GO:0048667 cell morphogenesis involved in neuron differentiation
1.63 1.27e-09 GO:0010628 positive regulation of gene expression
1.75 1.27e-09 GO:0019226 transmission of nerve impulse
1.75 1.27e-09 GO:0035637 multicellular organismal signaling
1.50 1.34e-09 GO:0007154 cell communication
1.79 1.62e-09 GO:0007268 synaptic transmission
1.44 1.65e-09 GO:0051239 regulation of multicellular organismal process
1.23 1.92e-09 GO:0023052 signaling
1.80 2.67e-09 GO:0007409 axonogenesis
1.58 3.08e-09 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.31 5.72e-09 GO:0051252 regulation of RNA metabolic process
1.51 9.11e-09 GO:0050793 regulation of developmental process
1.57 9.24e-09 GO:0007267 cell-cell signaling
1.55 1.14e-08 GO:0051173 positive regulation of nitrogen compound metabolic process
1.89 1.29e-08 GO:0060284 regulation of cell development
1.23 1.59e-08 GO:0031323 regulation of cellular metabolic process
1.64 1.62e-08 GO:0000902 cell morphogenesis
1.21 1.86e-08 GO:0019222 regulation of metabolic process
1.70 1.91e-08 GO:0048858 cell projection morphogenesis
1.62 2.13e-08 GO:0032989 cellular component morphogenesis
1.27 2.15e-08 GO:0031326 regulation of cellular biosynthetic process
1.62 2.57e-08 GO:0045893 positive regulation of transcription, DNA-dependent
1.59 2.64e-08 GO:0051254 positive regulation of RNA metabolic process
1.23 2.92e-08 GO:0080090 regulation of primary metabolic process
1.30 3.51e-08 GO:0006355 regulation of transcription, DNA-dependent
1.68 4.02e-08 GO:0032990 cell part morphogenesis
1.27 4.09e-08 GO:0009889 regulation of biosynthetic process
1.55 4.64e-08 GO:2000026 regulation of multicellular organismal development
1.57 7.28e-08 GO:0009790 embryo development
1.28 2.22e-07 GO:0048519 negative regulation of biological process
1.26 3.26e-07 GO:0010468 regulation of gene expression
1.34 3.72e-07 GO:0023051 regulation of signaling
1.29 4.03e-07 GO:0048523 negative regulation of cellular process
1.57 5.32e-07 GO:0030030 cell projection organization
1.22 5.89e-07 GO:0060255 regulation of macromolecule metabolic process
1.52 8.24e-07 GO:0010557 positive regulation of macromolecule biosynthetic process
1.47 1.29e-06 GO:0009891 positive regulation of biosynthetic process
1.78 1.39e-06 GO:0007411 axon guidance
1.47 2.18e-06 GO:0031328 positive regulation of cellular biosynthetic process
1.46 2.33e-06 GO:0040011 locomotion
1.30 3.29e-06 GO:0007166 cell surface receptor linked signaling pathway
1.37 3.87e-06 GO:0009893 positive regulation of metabolic process
1.83 4.43e-06 GO:0051960 regulation of nervous system development
1.85 5.65e-06 GO:0045596 negative regulation of cell differentiation
1.25 5.69e-06 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.38 5.83e-06 GO:0010604 positive regulation of macromolecule metabolic process
1.21 6.52e-06 GO:0007165 signal transduction
1.67 9.90e-06 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.18 1.02e-05 GO:0051716 cellular response to stimulus
1.69 1.15e-05 GO:0043009 chordate embryonic development
1.69 1.15e-05 GO:0009792 embryo development ending in birth or egg hatching
1.24 1.22e-05 GO:0010556 regulation of macromolecule biosynthetic process
1.39 1.51e-05 GO:0010646 regulation of cell communication
1.36 2.20e-05 GO:0031325 positive regulation of cellular metabolic process
1.68 2.38e-05 GO:0048598 embryonic morphogenesis
1.40 3.07e-05 GO:0009605 response to external stimulus
1.83 3.20e-05 GO:0050767 regulation of neurogenesis
1.55 4.30e-05 GO:0045892 negative regulation of transcription, DNA-dependent
1.67 4.86e-05 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
1.07 7.28e-05 GO:0009987 cellular process
1.53 9.97e-05 GO:0051253 negative regulation of RNA metabolic process
2.13 1.01e-04 GO:0010769 regulation of cell morphogenesis involved in differentiation
1.68 1.16e-04 GO:0044057 regulation of system process
1.95 1.18e-04 GO:0030900 forebrain development
2.11 1.38e-04 GO:0022604 regulation of cell morphogenesis
1.68 1.64e-04 GO:0051093 negative regulation of developmental process
1.53 1.83e-04 GO:0006935 chemotaxis
1.53 1.83e-04 GO:0042330 taxis
1.46 2.01e-04 GO:0031327 negative regulation of cellular biosynthetic process
1.58 2.29e-04 GO:0032583 regulation of gene-specific transcription
1.37 2.45e-04 GO:0032879 regulation of localization
1.48 3.24e-04 GO:0010629 negative regulation of gene expression
1.45 3.41e-04 GO:0009890 negative regulation of biosynthetic process
1.95 4.57e-04 GO:0006813 potassium ion transport
1.83 5.80e-04 GO:0045664 regulation of neuron differentiation
1.38 6.85e-04 GO:0006351 transcription, DNA-dependent
1.25 8.62e-04 GO:0048583 regulation of response to stimulus
1.69 1.13e-03 GO:0035295 tube development
1.61 1.32e-03 GO:0007389 pattern specification process
1.54 1.42e-03 GO:0046903 secretion
1.82 1.54e-03 GO:0032582 negative regulation of gene-specific transcription
1.28 1.70e-03 GO:0009966 regulation of signal transduction
1.91 1.78e-03 GO:0010553 negative regulation of gene-specific transcription from RNA polymerase II promoter
1.66 2.34e-03 GO:0007423 sensory organ development
1.42 2.89e-03 GO:0010558 negative regulation of macromolecule biosynthetic process
1.43 4.79e-03 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.70 5.40e-03 GO:0048568 embryonic organ development
2.30 6.24e-03 GO:0048638 regulation of developmental growth
1.61 6.35e-03 GO:0022603 regulation of anatomical structure morphogenesis
2.23 7.14e-03 GO:0021953 central nervous system neuron differentiation
1.69 7.85e-03 GO:0003002 regionalization
1.42 8.14e-03 GO:0051172 negative regulation of nitrogen compound metabolic process
1.47 8.55e-03 GO:0030001 metal ion transport
2.27 9.05e-03 GO:0010721 negative regulation of cell development
1.87 9.39e-03 GO:0045165 cell fate commitment
1.57 9.46e-03 GO:0045597 positive regulation of cell differentiation
1.42 9.87e-03 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.86 1.19e-02 GO:0060562 epithelial tube morphogenesis
1.10 1.27e-02 GO:0050896 response to stimulus
1.34 1.46e-02 GO:0009888 tissue development
1.59 1.47e-02 GO:0048729 tissue morphogenesis
1.20 1.68e-02 GO:0042221 response to chemical stimulus
2.08 1.74e-02 GO:0021537 telencephalon development
1.20 1.97e-02 GO:0065008 regulation of biological quality
1.90 2.07e-02 GO:0030799 regulation of cyclic nucleotide metabolic process
1.89 2.65e-02 GO:0051969 regulation of transmission of nerve impulse
1.96 2.87e-02 GO:0072001 renal system development
3.12 3.44e-02 GO:0071300 cellular response to retinoic acid
1.59 3.53e-02 GO:0061061 muscle structure development
1.82 4.01e-02 GO:0031644 regulation of neurological system process
1.37 4.29e-02 GO:0007167 enzyme linked receptor protein signaling pathway
2.49 4.55e-02 GO:0048863 stem cell differentiation

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.69 8.40e-12 GO:0030054 cell junction
1.83 4.49e-11 GO:0045202 synapse
1.31 5.33e-10 GO:0044459 plasma membrane part
1.90 1.92e-09 GO:0044456 synapse part
1.95 3.03e-07 GO:0034702 ion channel complex
2.12 3.56e-06 GO:0034703 cation channel complex
1.16 1.68e-05 GO:0005886 plasma membrane
1.15 8.02e-05 GO:0071944 cell periphery
1.93 1.45e-04 GO:0045211 postsynaptic membrane
1.57 1.78e-04 GO:0031012 extracellular matrix
2.21 2.92e-04 GO:0008076 voltage-gated potassium channel complex
2.21 2.92e-04 GO:0034705 potassium channel complex
1.30 2.96e-04 GO:0005887 integral to plasma membrane
1.29 3.94e-04 GO:0031226 intrinsic to plasma membrane
1.31 4.01e-04 GO:0000267 cell fraction
1.52 8.17e-04 GO:0043005 neuron projection
1.35 9.92e-04 GO:0005626 insoluble fraction
1.35 1.19e-03 GO:0005624 membrane fraction
1.57 1.51e-03 GO:0005578 proteinaceous extracellular matrix
1.78 6.13e-03 GO:0005912 adherens junction
2.04 1.68e-02 GO:0014069 postsynaptic density
1.26 2.13e-02 GO:0044421 extracellular region part
1.89 2.77e-02 GO:0005925 focal adhesion
1.85 3.76e-02 GO:0005924 cell-substrate adherens junction

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.85 1.26e-20 GO:0043565 sequence-specific DNA binding
1.61 7.74e-16 GO:0030528 transcription regulator activity
1.56 4.31e-13 GO:0001071 nucleic acid binding transcription factor activity
1.56 4.31e-13 GO:0003700 sequence-specific DNA binding transcription factor activity
1.14 1.22e-09 GO:0005515 protein binding
2.31 6.85e-09 GO:0022843 voltage-gated cation channel activity
1.93 7.07e-09 GO:0005261 cation channel activity
1.75 1.15e-08 GO:0022838 substrate-specific channel activity
1.85 1.72e-08 GO:0022836 gated channel activity
1.73 3.57e-08 GO:0005216 ion channel activity
1.70 1.18e-07 GO:0015267 channel activity
1.69 1.43e-07 GO:0022803 passive transmembrane transporter activity
2.03 2.43e-07 GO:0005244 voltage-gated ion channel activity
2.03 2.43e-07 GO:0022832 voltage-gated channel activity
1.93 2.02e-06 GO:0000975 regulatory region DNA binding
1.93 2.02e-06 GO:0001067 regulatory region nucleic acid binding
1.93 2.02e-06 GO:0044212 transcription regulatory region DNA binding
1.93 4.32e-06 GO:0010843 promoter binding
2.15 1.01e-05 GO:0005267 potassium channel activity
1.70 1.40e-05 GO:0016563 transcription activator activity
1.06 1.44e-05 GO:0005488 binding
2.23 7.25e-05 GO:0005249 voltage-gated potassium channel activity
1.54 1.73e-04 GO:0019904 protein domain specific binding
1.21 2.18e-04 GO:0003677 DNA binding
1.42 2.50e-03 GO:0008324 cation transmembrane transporter activity
1.30 4.08e-03 GO:0005102 receptor binding
1.56 4.61e-03 GO:0016564 transcription repressor activity
1.34 7.29e-03 GO:0015075 ion transmembrane transporter activity
1.96 2.83e-02 GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity