Motif ID: RREB1.p2

Z-value: 6.538


Transcription factors associated with RREB1.p2:

Gene SymbolEntrez IDGene Name
RREB1 6239 ras responsive element binding protein 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
RREB1chr6_+_70538630.273.1e-01Click!


Activity profile for motif RREB1.p2.

activity profile for motif RREB1.p2


Sorted Z-values histogram for motif RREB1.p2

Sorted Z-values for motif RREB1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of RREB1.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chrX_+_17665483 13.561 NM_001037535
NM_001037536
NM_001037540
NM_006746
 SCML1



sex comb on midleg-like 1 (Drosophila)



chr16_-_3225360 12.899 NM_001145448
NM_198088
NM_001145446
NM_198087
 ZNF200



zinc finger protein 200



chr19_-_55914837 11.438


chr4_-_809879 10.971 NM_006651
 CPLX1
complexin 1
chr20_+_55359551 10.379 NM_003610
 RAE1
RAE1 RNA export 1 homolog (S. pombe)
chr3_+_187917791 9.860 NM_000893
NM_001102416
NM_001166451
 KNG1


kininogen 1


chr20_+_55359706 9.809 RAE1
RAE1 RNA export 1 homolog (S. pombe)
chr21_+_42946719 9.569 NM_001001567
NM_001001568
NM_001001569
NM_001001570
NM_001001571
NM_001001572
NM_001001573
NM_001001574
NM_001001575
NM_001001576
NM_001001577
NM_001001578
NM_001001579
NM_001001580
NM_001001581
NM_001001582
NM_001001583
NM_001001584
NM_001001585
NM_002606
 PDE9A



















phosphodiesterase 9A



















chr16_-_3225070 9.377 NM_001145447
NM_003454
 ZNF200

zinc finger protein 200

chr19_-_51168396 8.656 NM_002516
 NOVA2
neuro-oncological ventral antigen 2
chr11_-_133786935 8.085 NM_018644
NM_054025
 B3GAT1

beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)

chr7_+_44110527 7.829 AEBP1
AE binding protein 1
chr7_+_44110470 7.677 NM_001129
 AEBP1
AE binding protein 1
chr4_-_46086528 7.496 NM_000807
 GABRA2
gamma-aminobutyric acid (GABA) A receptor, alpha 2
chr16_+_86193993 6.947 NM_020655
 JPH3
junctophilin 3
chr1_-_202647526 6.922 NM_032833
 PPP1R15B
protein phosphatase 1, regulatory (inhibitor) subunit 15B
chr19_+_3317589 6.829 NFIC
nuclear factor I/C (CCAAT-binding transcription factor)
chr22_+_48966394 6.812 TRABD
TraB domain containing
chr4_+_191235959 6.684 NM_001177376
 DUX4L4
double homeobox 4 like 4
chr22_+_48966480 6.654 NM_025204
 TRABD
TraB domain containing

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 143 entries
enrichment   p-value GO term description
3.12 3.44e-02 GO:0071300 cellular response to retinoic acid
2.49 4.55e-02 GO:0048863 stem cell differentiation
2.30 6.24e-03 GO:0048638 regulation of developmental growth
2.27 9.05e-03 GO:0010721 negative regulation of cell development
2.23 7.14e-03 GO:0021953 central nervous system neuron differentiation
2.13 1.01e-04 GO:0010769 regulation of cell morphogenesis involved in differentiation
2.11 1.38e-04 GO:0022604 regulation of cell morphogenesis
2.08 1.74e-02 GO:0021537 telencephalon development
1.96 2.87e-02 GO:0072001 renal system development
1.95 1.18e-04 GO:0030900 forebrain development
1.95 4.57e-04 GO:0006813 potassium ion transport
1.93 5.10e-16 GO:0007417 central nervous system development
1.92 1.14e-10 GO:0007420 brain development
1.91 1.78e-03 GO:0010553 negative regulation of gene-specific transcription from RNA polymerase II promoter
1.90 2.07e-02 GO:0030799 regulation of cyclic nucleotide metabolic process
1.89 1.29e-08 GO:0060284 regulation of cell development
1.89 2.65e-02 GO:0051969 regulation of transmission of nerve impulse
1.87 9.39e-03 GO:0045165 cell fate commitment
1.86 1.19e-02 GO:0060562 epithelial tube morphogenesis
1.85 5.65e-06 GO:0045596 negative regulation of cell differentiation

Gene overrepresentation in compartment category:

Showing 1 to 20 of 24 entries
enrichment   p-value GO term description
2.21 2.92e-04 GO:0008076 voltage-gated potassium channel complex
2.21 2.92e-04 GO:0034705 potassium channel complex
2.12 3.56e-06 GO:0034703 cation channel complex
2.04 1.68e-02 GO:0014069 postsynaptic density
1.95 3.03e-07 GO:0034702 ion channel complex
1.93 1.45e-04 GO:0045211 postsynaptic membrane
1.90 1.92e-09 GO:0044456 synapse part
1.89 2.77e-02 GO:0005925 focal adhesion
1.85 3.76e-02 GO:0005924 cell-substrate adherens junction
1.83 4.49e-11 GO:0045202 synapse
1.78 6.13e-03 GO:0005912 adherens junction
1.69 8.40e-12 GO:0030054 cell junction
1.57 1.78e-04 GO:0031012 extracellular matrix
1.57 1.51e-03 GO:0005578 proteinaceous extracellular matrix
1.52 8.17e-04 GO:0043005 neuron projection
1.35 9.92e-04 GO:0005626 insoluble fraction
1.35 1.19e-03 GO:0005624 membrane fraction
1.31 5.33e-10 GO:0044459 plasma membrane part
1.31 4.01e-04 GO:0000267 cell fraction
1.30 2.96e-04 GO:0005887 integral to plasma membrane

Gene overrepresentation in function category:

Showing 1 to 20 of 29 entries
enrichment   p-value GO term description
2.31 6.85e-09 GO:0022843 voltage-gated cation channel activity
2.23 7.25e-05 GO:0005249 voltage-gated potassium channel activity
2.15 1.01e-05 GO:0005267 potassium channel activity
2.03 2.43e-07 GO:0005244 voltage-gated ion channel activity
2.03 2.43e-07 GO:0022832 voltage-gated channel activity
1.96 2.83e-02 GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity
1.93 7.07e-09 GO:0005261 cation channel activity
1.93 2.02e-06 GO:0000975 regulatory region DNA binding
1.93 2.02e-06 GO:0001067 regulatory region nucleic acid binding
1.93 2.02e-06 GO:0044212 transcription regulatory region DNA binding
1.93 4.32e-06 GO:0010843 promoter binding
1.85 1.26e-20 GO:0043565 sequence-specific DNA binding
1.85 1.72e-08 GO:0022836 gated channel activity
1.75 1.15e-08 GO:0022838 substrate-specific channel activity
1.73 3.57e-08 GO:0005216 ion channel activity
1.70 1.18e-07 GO:0015267 channel activity
1.70 1.40e-05 GO:0016563 transcription activator activity
1.69 1.43e-07 GO:0022803 passive transmembrane transporter activity
1.61 7.74e-16 GO:0030528 transcription regulator activity
1.56 4.31e-13 GO:0001071 nucleic acid binding transcription factor activity