Motif ID: RUNX1..3.p2

Z-value: 2.143


Transcription factors associated with RUNX1..3.p2:

Gene SymbolEntrez IDGene Name
RUNX1 861 runt-related transcription factor 1
RUNX2 860 runt-related transcription factor 2
RUNX3 864 runt-related transcription factor 3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
RUNX2chr6_+_45497796-0.543.0e-02Click!
RUNX1chr21_-_351536640.448.6e-02Click!
RUNX3chr1_-_251640610.401.2e-01Click!


Activity profile for motif RUNX1..3.p2.

activity profile for motif RUNX1..3.p2


Sorted Z-values histogram for motif RUNX1..3.p2

Sorted Z-values for motif RUNX1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of RUNX1..3.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr22_+_21318779 2.993 NM_199127
 GGTLC2
gamma-glutamyltransferase light chain 2
chr17_-_3442871 2.443 NM_080706
 TRPV1
transient receptor potential cation channel, subfamily V, member 1
chr20_-_23915431 2.242 NM_178312
 GGTLC1
gamma-glutamyltransferase light chain 1
chr7_+_142850667 2.217 NM_177437
 TAS2R60
taste receptor, type 2, member 60
chr6_+_30212488 2.135 NM_138700
 TRIM40
tripartite motif containing 40
chr1_+_22200735 2.057 NM_005747
 CELA3A
chymotrypsin-like elastase family, member 3A
chr13_+_112789669 1.910 MCF2L
MCF.2 cell line derived transforming sequence-like
chr1_+_207995999 1.906 NM_025228
 TRAF3IP3
TRAF3 interacting protein 3
chr11_-_31782169 1.897 PAX6
paired box 6
chrX_+_71280758 1.784 NM_207422
 FLJ44635
TPT1-like protein
chr1_-_166779825 1.781 NM_003175
 XCL1
XCL2
chemokine (C motif) ligand 1
chemokine (C motif) ligand 2
chr6_+_155579788 1.763 NM_001010927
 TIAM2
T-cell lymphoma invasion and metastasis 2
chr5_+_156628929 1.692 NM_014376
 CYFIP2
cytoplasmic FMR1 interacting protein 2
chr18_+_18989786 1.642 NM_138375
 CABLES1
Cdk5 and Abl enzyme substrate 1
chr14_+_60045621 1.640 NM_007374
 SIX6
SIX homeobox 6
chr6_-_11490487 1.619 NM_001142393
 NEDD9
neural precursor cell expressed, developmentally down-regulated 9
chr8_+_124032830 1.564 ZHX2
zinc fingers and homeoboxes 2
chr1_-_201583989 1.556 FMOD
fibromodulin
chr3_+_101811122 1.544 NM_032787
 GPR128
G protein-coupled receptor 128
chr22_+_20350272 1.535 NM_014337
NM_148175
NM_148176
 PPIL2


peptidylprolyl isomerase (cyclophilin)-like 2



Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 16 of 16 entries
enrichment   p-value GO term description
2.29 4.59e-10 GO:0007608 sensory perception of smell
2.22 3.70e-10 GO:0007606 sensory perception of chemical stimulus
1.70 6.45e-06 GO:0007600 sensory perception
1.67 2.88e-02 GO:0001775 cell activation
1.56 1.14e-02 GO:0006955 immune response
1.53 7.34e-06 GO:0050877 neurological system process
1.50 6.23e-03 GO:0032879 regulation of localization
1.49 1.44e-06 GO:0003008 system process
1.47 1.05e-03 GO:0002376 immune system process
1.33 1.94e-02 GO:0048583 regulation of response to stimulus
1.30 9.29e-15 GO:0050896 response to stimulus
1.28 1.40e-04 GO:0007165 signal transduction
1.26 1.58e-04 GO:0023052 signaling
1.25 3.14e-07 GO:0032501 multicellular organismal process
1.25 4.09e-02 GO:0048518 positive regulation of biological process
1.20 3.45e-02 GO:0051716 cellular response to stimulus

Gene overrepresentation in compartment category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
1.44 4.31e-02 GO:0005615 extracellular space
1.40 5.62e-16 GO:0005886 plasma membrane
1.39 9.58e-16 GO:0071944 cell periphery
1.35 4.14e-05 GO:0044459 plasma membrane part
1.18 4.71e-04 GO:0031224 intrinsic to membrane
1.17 6.17e-05 GO:0044425 membrane part
1.17 1.43e-03 GO:0016021 integral to membrane
1.13 1.64e-03 GO:0016020 membrane

Gene overrepresentation in function category:

Showing 1 to 9 of 9 entries
enrichment   p-value GO term description
3.38 4.11e-02 GO:0003823 antigen binding
3.19 2.51e-02 GO:0005070 SH3/SH2 adaptor activity
2.29 4.15e-10 GO:0004984 olfactory receptor activity
2.14 3.81e-03 GO:0005126 cytokine receptor binding
1.69 1.10e-06 GO:0004930 G-protein coupled receptor activity
1.61 2.16e-08 GO:0004888 transmembrane receptor activity
1.57 2.02e-10 GO:0004872 receptor activity
1.47 5.45e-09 GO:0004871 signal transducer activity
1.47 5.45e-09 GO:0060089 molecular transducer activity