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• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: RXRG_dimer.p3

Z-value: 0.991

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr2_-_175754366	1.641	NM_001002258 NM_001190329 NM_001689	ATP5G3	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)
chr20_+_37024383	1.591	NM_001190809 NM_021931	DHX35	DEAH (Asp-Glu-Ala-His) box polypeptide 35
chr2_+_219141761	1.383	NM_005444	RQCD1	RCD1 required for cell differentiation1 homolog (S. pombe)
chr2_+_161725172	1.201		TANK	TRAF family member-associated NFKB activator
chr5_+_1854493	1.176	NM_004553	NDUFS6	NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase)
chr10_-_21854616	1.157	NM_207371	C10orf140	chromosome 10 open reading frame 140
chr19_+_44308224	1.142	NM_001014831 NM_001014832 NM_001014834 NM_001014835 NM_005884	PAK4	p21 protein (Cdc42/Rac)-activated kinase 4
chr4_+_109761170	1.122	NM_000995 NM_033625	RPL34	ribosomal protein L34
chr6_+_30702586	1.114	NM_024909 NM_001031722 NM_001190724	ATAT1	alpha tubulin acetyltransferase 1
chr6_+_144040751	1.106	NM_001100164 NM_001100165	PHACTR2	phosphatase and actin regulator 2
chr2_+_108432097	1.081		GCC2	GRIP and coiled-coil domain containing 2
chr2_+_108432008	1.069	NM_181453	GCC2	GRIP and coiled-coil domain containing 2
chr18_+_52469559	1.051	NM_015285 NM_052834	WDR7	WD repeat domain 7
chr20_-_19981005	1.042		CRNKL1	crooked neck pre-mRNA splicing factor-like 1 (Drosophila)
chr14_-_20642214	0.987
chr6_+_143813472	0.941	NM_003630	PEX3	peroxisomal biogenesis factor 3
chr12_+_14429499	0.924		ATF7IP	activating transcription factor 7 interacting protein
chr2_-_219141199	0.910	NM_020935	USP37	ubiquitin specific peptidase 37
chr5_-_42847716	0.892	NM_001085486 NM_001093726 NM_005410	SEPP1	selenoprotein P, plasma, 1
chr20_+_19981157	0.865	NM_015585	C20orf26	chromosome 20 open reading frame 26
chr1_+_61320213	0.852	NM_001134673 NM_005595	NFIA	nuclear factor I/A
chr1_-_32632601	0.790	NM_001143888 NM_001143889 NM_001143890 NM_018045	BSDC1	BSD domain containing 1
chr20_+_36095263	0.788	NM_021215	RPRD1B	regulation of nuclear pre-mRNA domain containing 1B
chr6_+_31731667	0.780		APOM	apolipoprotein M
chr6_+_31731647	0.772	NM_019101	APOM	apolipoprotein M
chr16_+_79829794	0.741	NM_017429	BCMO1	beta-carotene 15,15'-monooxygenase 1
chr10_-_103805858	0.719	NM_024541	C10orf76	chromosome 10 open reading frame 76
chr20_+_43943254	0.699	NM_080603	ZSWIM1	zinc finger, SWIM-type containing 1
chr9_-_138277467	0.698	NM_181701	QSOX2	quiescin Q6 sulfhydryl oxidase 2
chr8_-_81104938	0.690	NM_014018	MRPS28	mitochondrial ribosomal protein S28
chr3_+_37259684	0.687	NM_001172713 NM_002078	GOLGA4	golgin A4
chr11_+_86426518	0.685	NM_001168724 NM_022918	TMEM135	transmembrane protein 135
chr2_+_138438277	0.683	NM_001024074 NM_001024075 NM_006895	HNMT	histamine N-methyltransferase
chr20_-_32363268	0.647	NM_001161766	AHCY	adenosylhomocysteinase
chr7_+_100450080	0.620	NM_001040105	MUC17	mucin 17, cell surface associated
chr2_+_177965734	0.619		AGPS	alkylglycerone phosphate synthase
chr11_+_85690900	0.619	NM_016401	C11orf73	chromosome 11 open reading frame 73
chr14_+_23937766	0.616	NM_025081	NYNRIN	NYN domain and retroviral integrase containing
chr2_+_219141546	0.615		RQCD1	RCD1 required for cell differentiation1 homolog (S. pombe)
chr20_+_36095621	0.601
chr17_+_35532994	0.595		MSL1	male-specific lethal 1 homolog (Drosophila)
chr19_+_16169664	0.595	NM_001130524 NM_032493	AP1M1	adaptor-related protein complex 1, mu 1 subunit
chr13_+_99539269	0.584	NM_000282 NM_001127692 NM_001178004	PCCA	propionyl CoA carboxylase, alpha polypeptide
chr12_-_6995988	0.577	NM_005768	LPCAT3	lysophosphatidylcholine acyltransferase 3
chr1_-_149404954	0.568	NM_212551 NM_001136543	LYSMD1	LysM, putative peptidoglycan-binding, domain containing 1
chr12_-_52407470	0.565	NM_001143682 NM_020898	CALCOCO1	calcium binding and coiled-coil domain 1
chr4_-_7120656	0.555	NM_025196	GRPEL1	GrpE-like 1, mitochondrial (E. coli)
chr20_+_36095552	0.555		RPRD1B	regulation of nuclear pre-mRNA domain containing 1B
chr11_+_118374071	0.552		CCDC84	coiled-coil domain containing 84
chr11_+_117948350	0.542		ARCN1	archain 1
chr12_+_65949631	0.537		CAND1	cullin-associated and neddylation-dissociated 1
chr22_+_28493351	0.527	NM_001003684 NM_013387	UQCR10	ubiquinol-cytochrome c reductase, complex III subunit X
chr11_+_118374051	0.520	NM_198489	CCDC84	coiled-coil domain containing 84
chr1_-_95311031	0.510	NM_144988	ALG14	asparagine-linked glycosylation 14 homolog (S. cerevisiae)
chr2_+_201691664	0.497		CFLAR	CASP8 and FADD-like apoptosis regulator
chr18_-_44730706	0.481		SMAD7	SMAD family member 7
chr2_+_119841611	0.479	NM_001079863	DBI	diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
chr17_-_2561676	0.470	NM_015229	KIAA0664	KIAA0664
chr6_-_39801088	0.453	NM_145027	KIF6	kinesin family member 6
chr20_+_42593849	0.436	NM_007066 NM_181804 NM_181805	PKIG	protein kinase (cAMP-dependent, catalytic) inhibitor gamma
chr20_+_55569542	0.431	NM_002591	PCK1	phosphoenolpyruvate carboxykinase 1 (soluble)
chr12_+_67489063	0.428		MDM2	Mdm2 p53 binding protein homolog (mouse)
chr2_+_206732859	0.426		EEF1B2	eukaryotic translation elongation factor 1 beta 2
chr6_-_146326918	0.422	NM_001042683 NM_173082	SHPRH	SNF2 histone linker PHD RING helicase
chr2_-_206732348	0.422	NM_005006	NDUFS1	NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
chr11_+_117948301	0.402	NM_001142281 NM_001655	ARCN1	archain 1
chr2_+_206732575	0.398		EEF1B2	eukaryotic translation elongation factor 1 beta 2
chr2_+_201691513	0.394	NM_001127183	CFLAR	CASP8 and FADD-like apoptosis regulator
chr2_+_198073358	0.383		HSPE1	heat shock 10kDa protein 1 (chaperonin 10)
chr11_-_116213511	0.382	NM_000039	APOA1	apolipoprotein A-I
chr6_+_142510094	0.381	NM_016485	VTA1	Vps20-associated 1 homolog (S. cerevisiae)
chr22_+_40195058	0.381	NM_001098	ACO2	aconitase 2, mitochondrial
chr6_-_32034607	0.373	NM_002904	RDBP	RD RNA binding protein
chr20_-_36095236	0.368	NM_014657	TTI1	Tel2 interacting protein 1 homolog (S. pombe)
chr2_+_206732562	0.362	NM_001037663 NM_001959 NM_021121	EEF1B2	eukaryotic translation elongation factor 1 beta 2
chr2_-_27966715	0.362	NM_022128	RBKS	ribokinase
chr8_+_96106362	0.354	NM_152416	C8orf38	chromosome 8 open reading frame 38
chr22_-_40194602	0.335	NM_032758	PHF5A	PHD finger protein 5A
chr6_+_142510108	0.326		VTA1	Vps20-associated 1 homolog (S. cerevisiae)
chr6_-_146327238	0.325		SHPRH	SNF2 histone linker PHD RING helicase
chr2_+_27966985	0.322	NM_199193 NM_199194 NM_004899 NM_199191 NM_199192	BRE	brain and reproductive organ-expressed (TNFRSF1A modulator)
chr12_-_49708279	0.317	NM_001174125	SLC11A2	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr6_+_142510075	0.317		VTA1	Vps20-associated 1 homolog (S. cerevisiae)
chr20_+_30409649	0.312	NM_001164603 NM_015338	ASXL1	additional sex combs like 1 (Drosophila)
chr14_-_94693359	0.310		DICER1	dicer 1, ribonuclease type III
chr6_+_142510034	0.310		VTA1	Vps20-associated 1 homolog (S. cerevisiae)
chr1_+_78126787	0.304	NM_001172309 NM_144573	NEXN	nexilin (F actin binding protein)
chr6_-_146326863	0.301		SHPRH	SNF2 histone linker PHD RING helicase
chr18_-_50004458	0.301		MBD2	methyl-CpG binding domain protein 2
chr2_+_73294852	0.301	NM_006062	SMYD5	SMYD family member 5
chr3_-_114947330	0.300		NAA50	N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr12_+_65949414	0.295		CAND1	cullin-associated and neddylation-dissociated 1
chr2_+_27967102	0.294		BRE	brain and reproductive organ-expressed (TNFRSF1A modulator)
chr22_-_49413326	0.294	NM_000487 NM_001085425 NM_001085426 NM_001085427 NM_001085428	ARSA	arylsulfatase A
chr20_-_7869068	0.289	NM_017545	HAO1	hydroxyacid oxidase (glycolate oxidase) 1
chr2_-_177965626	0.289		LOC100130691	hypothetical LOC100130691
chr17_-_8138849	0.288	NM_201520	SLC25A35	solute carrier family 25, member 35
chr6_-_33879734	0.287	NM_001040109 NM_001184698 NM_002418	MLN	motilin
chr18_-_44731078	0.279	NM_001190821 NM_005904	SMAD7	SMAD family member 7
chr12_+_94776836	0.277	NM_003095	SNRPF	small nuclear ribonucleoprotein polypeptide F
chr7_-_106991941	0.272	NM_001161520 NM_006348 NM_181733	COG5	component of oligomeric golgi complex 5
chr16_+_4415805	0.270	NM_001135110 NM_005147	DNAJA3	DnaJ (Hsp40) homolog, subfamily A, member 3
chr16_-_86527608	0.266	NM_001739	CA5A	carbonic anhydrase VA, mitochondrial
chr11_-_123261549	0.261	NM_001013743	TMEM225	transmembrane protein 225
chr4_+_30330963	0.257	NM_001173523 NM_002589 NM_032456 NM_032457	PCDH7	protocadherin 7
chr18_-_50004770	0.254		MBD2	methyl-CpG binding domain protein 2
chr6_-_146327155	0.251		SHPRH	SNF2 histone linker PHD RING helicase
chr6_-_2696152	0.248	NM_001012418	MYLK4	myosin light chain kinase family, member 4
chr2_+_27967116	0.243		BRE	brain and reproductive organ-expressed (TNFRSF1A modulator)
chr7_-_72574383	0.243		BAZ1B	bromodomain adjacent to zinc finger domain, 1B
chr2_+_220007943	0.238	NM_005876	SPEG	SPEG complex locus
chr2_+_177965617	0.234	NM_003659	AGPS	alkylglycerone phosphate synthase
chr4_-_141294682	0.234	NM_018717	MAML3	mastermind-like 3 (Drosophila)
chr20_+_43919662	0.232	NM_080752	ZSWIM3	zinc finger, SWIM-type containing 3
chr17_-_8139330	0.229		SLC25A35	solute carrier family 25, member 35
chr6_+_32034767	0.220		SKIV2L	superkiller viralicidic activity 2-like (S. cerevisiae)
chr2_+_27967159	0.219		BRE	brain and reproductive organ-expressed (TNFRSF1A modulator)
chr17_+_43328514	0.218	NM_003110	SP2	Sp2 transcription factor
chr12_+_54910767	0.212	NM_001135195	SLC39A5	solute carrier family 39 (metal ion transporter), member 5
chr6_-_2785682	0.212		SERPINB1	serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr5_+_132237253	0.212	NM_052971	LEAP2	liver expressed antimicrobial peptide 2
chr7_+_120415958	0.211	NM_024913	C7orf58	chromosome 7 open reading frame 58
chr14_+_49157150	0.210	NM_002408	MGAT2	mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr15_+_94674849	0.210	NM_021005	NR2F2	nuclear receptor subfamily 2, group F, member 2
chr17_-_40344322	0.209
chr1_-_101263867	0.207	NM_001077394 NM_001077395 NM_015958	DPH5	DPH5 homolog (S. cerevisiae)
chr17_+_38403991	0.204		RPL27	ribosomal protein L27
chr12_+_94776901	0.203		SNRPF	small nuclear ribonucleoprotein polypeptide F
chr11_-_65962836	0.200	NM_016050 NM_170738 NM_170739	MRPL11	mitochondrial ribosomal protein L11
chr4_+_140806536	0.195		MGST2	microsomal glutathione S-transferase 2
chr2_-_24160683	0.187		TP53I3	tumor protein p53 inducible protein 3
chr2_-_64099935	0.185		VPS54	vacuolar protein sorting 54 homolog (S. cerevisiae)
chr4_+_30331289	0.182		PCDH7	protocadherin 7
chr1_-_209915443	0.181	NM_002497	NEK2	NIMA (never in mitosis gene a)-related kinase 2
chr16_+_3102556	0.178	NM_001042428 NM_003456	ZNF205	zinc finger protein 205
chr12_+_48003237	0.178	NM_001100620 NM_005480	TROAP	trophinin associated protein (tastin)
chr2_-_219742950	0.176	NM_001144889 NM_001144890 NM_144712	SLC23A3	solute carrier family 23 (nucleobase transporters), member 3
chr2_-_191107660	0.172		TMEM194B	transmembrane protein 194B
chr16_+_31446703	0.171	NM_016633	AHSP	alpha hemoglobin stabilizing protein
chr17_+_7474128	0.170		SHBG	sex hormone-binding globulin
chr1_-_120112989	0.169	NM_001166107 NM_005518	HMGCS2	3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
chr21_+_44256630	0.166	NM_003274	TRAPPC10	trafficking protein particle complex 10
chr20_-_54400628	0.164	NM_003600 NM_198433 NM_198434 NM_198435 NM_198436 NM_198437	AURKA	aurora kinase A
chr2_+_119841298	0.159	NM_001178017	DBI	diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
chr2_-_159021201	0.155	NM_001171637 NM_138803	CCDC148	coiled-coil domain containing 148
chr1_+_101263989	0.154
chr2_+_26422495	0.152		EPT1	ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific)
chr20_-_43919360	0.152	NM_005469	ACOT8	acyl-CoA thioesterase 8
chr17_+_7474177	0.147	NM_001040 NM_001146279 NM_001146280 NM_001146281	SHBG	sex hormone-binding globulin
chr20_-_34005619	0.144		SCAND1	SCAN domain containing 1
chr19_+_60691733	0.143		SSC5D	scavenger receptor cysteine rich domain containing (5 domains)
chr14_+_94693744	0.140		FLJ45244	hypothetical locus FLJ45244
chr7_-_25131427	0.137	NM_018947	CYCS	cytochrome c, somatic
chr12_+_105692466	0.135	NM_018157	RIC8B	resistance to inhibitors of cholinesterase 8 homolog B (C. elegans)
chr17_-_40344203	0.133		GFAP	glial fibrillary acidic protein
chr2_-_19421852	0.133	NM_145260	OSR1	odd-skipped related 1 (Drosophila)
chr5_+_172416959	0.132		C5orf41	chromosome 5 open reading frame 41
chr1_-_224441024	0.130	NM_022735	ACBD3	acyl-CoA binding domain containing 3
chr9_+_108726257	0.126		ZNF462	zinc finger protein 462
chr2_+_159021653	0.125		PKP4	plakophilin 4
chr17_+_71508581	0.123	NM_001258	CDK3	cyclin-dependent kinase 3
chr2_+_198073257	0.120		HSPE1	heat shock 10kDa protein 1 (chaperonin 10)
chr20_+_54400979	0.117	NM_001324	CSTF1	cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa
chr2_+_218843358	0.117	NM_001077399 NM_015488	PNKD	paroxysmal nonkinesigenic dyskinesia
chr1_-_6684465	0.114		DNAJC11	DnaJ (Hsp40) homolog, subfamily C, member 11
chr14_-_94693418	0.108	NM_177438	DICER1	dicer 1, ribonuclease type III
chr8_-_42817604	0.107	NM_018105 NM_199003	THAP1	THAP domain containing, apoptosis associated protein 1
chr17_+_7063970	0.106		ACADVL	acyl-CoA dehydrogenase, very long chain
chr17_-_7064092	0.105	NM_001365	DLG4	discs, large homolog 4 (Drosophila)
chr6_+_32034559	0.104	NM_006929	SKIV2L	superkiller viralicidic activity 2-like (S. cerevisiae)
chr1_+_144439069	0.104	NM_002614	PDZK1	PDZ domain containing 1
chr12_-_49706190	0.103	NM_001174129	SLC11A2	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr1_+_149405128	0.102	NM_024041	SCNM1	sodium channel modifier 1
chr7_-_72574474	0.099		BAZ1B	bromodomain adjacent to zinc finger domain, 1B
chr8_-_82769761	0.099	NM_001010893	SLC10A5	solute carrier family 10 (sodium/bile acid cotransporter family), member 5
chr20_-_34005799	0.098	NM_016558 NM_033630	SCAND1	SCAN domain containing 1
chr12_-_49706364	0.098	NM_000617 NM_001174126 NM_001174127 NM_001174128	SLC11A2	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr17_+_3324096	0.097	NM_001128085	ASPA	aspartoacylase
chr19_+_6323443	0.093	NM_032306	ALKBH7	alkB, alkylation repair homolog 7 (E. coli)
chr2_+_219354692	0.092	NM_000784	CYP27A1	cytochrome P450, family 27, subfamily A, polypeptide 1
chr2_+_218992053	0.092	NM_007127	VIL1	villin 1
chr7_-_25131386	0.092		CYCS	cytochrome c, somatic
chr16_-_45564984	0.091		DNAJA2	DnaJ (Hsp40) homolog, subfamily A, member 2
chr9_+_91123204	0.088	NM_024077	SECISBP2	SECIS binding protein 2
chr17_+_38403935	0.083	NM_000988	RPL27	ribosomal protein L27
chr1_-_6684426	0.082		DNAJC11	DnaJ (Hsp40) homolog, subfamily C, member 11
chr1_+_45046740	0.080	NM_001136537	BTBD19	BTB (POZ) domain containing 19
chr2_-_198073242	0.077	NM_199440	HSPD1	heat shock 60kDa protein 1 (chaperonin)
chr8_-_71478560	0.077	NM_006540	NCOA2	nuclear receptor coactivator 2
chr15_-_100009860	0.071	NM_025141 NM_078474	TM2D3	TM2 domain containing 3
chr12_+_65949327	0.070	NM_018448	CAND1	cullin-associated and neddylation-dissociated 1
chr4_-_102487356	0.070		PPP3CA	protein phosphatase 3, catalytic subunit, alpha isozyme
chr4_-_4594620	0.070		STX18	syntaxin 18
chr16_-_45565068	0.069	NM_005880	DNAJA2	DnaJ (Hsp40) homolog, subfamily A, member 2
chr20_+_41621079	0.067	NM_170693	SGK2	serum/glucocorticoid regulated kinase 2
chr19_-_43498220	0.066	NM_001039671 NM_001145461 NM_001145462	YIF1B	Yip1 interacting factor homolog B (S. cerevisiae)
chr3_-_50580066	0.065	NM_001171740 NM_001171743 NM_016210	C3orf18	chromosome 3 open reading frame 18
chr3_-_151746821	0.065		SERP1	stress-associated endoplasmic reticulum protein 1
chr4_+_4594619	0.063		LOC100507266	hypothetical LOC100507266
chr13_+_20612709	0.062		SAP18	Sin3A-associated protein, 18kDa

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.46	3.28e-03	GO:0044237	cellular metabolic process
1.39	1.08e-02	GO:0008152	metabolic process
8.95	1.11e-02	GO:0031647	regulation of protein stability

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
4.31	2.23e-03	GO:0005759	mitochondrial matrix
2.70	7.10e-03	GO:0044429	mitochondrial part
2.11	9.25e-03	GO:0005739	mitochondrion
3.54	1.68e-02	GO:0005743	mitochondrial inner membrane
3.26	3.90e-02	GO:0019866	organelle inner membrane

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
8.60	1.45e-02	GO:0033293	monocarboxylic acid binding
5.78	1.61e-02	GO:0051082	unfolded protein binding

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