Motif ID: SPI1.p2

Z-value: 2.061


Transcription factors associated with SPI1.p2:

Gene SymbolEntrez IDGene Name
SPI1 6688 spleen focus forming virus (SFFV) proviral integration oncogene spi1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SPI1chr11_-_473566720.282.9e-01Click!


Activity profile for motif SPI1.p2.

activity profile for motif SPI1.p2


Sorted Z-values histogram for motif SPI1.p2

Sorted Z-values for motif SPI1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SPI1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_-_26395420 1.456 NM_001145168
NM_001145169
 GPR113

G protein-coupled receptor 113

chr2_-_152663748 1.408 NM_000726
NM_001145798
 CACNB4

calcium channel, voltage-dependent, beta 4 subunit

chr6_-_32265489 1.403 NM_002586
 PBX2
pre-B-cell leukemia homeobox 2
chr20_-_32877029 1.393 NM_014071
 NCOA6
nuclear receptor coactivator 6
chr6_-_33016561 1.382 NM_002118
 HLA-DMB
major histocompatibility complex, class II, DM beta
chr2_-_148494732 1.366 NM_001190882
NM_001190879
NM_002552
NM_001190881
NM_181741
 ORC4




origin recognition complex, subunit 4




chr14_-_37134191 1.295 NM_004496
 FOXA1
forkhead box A1
chr2_+_138438277 1.290 NM_001024074
NM_001024075
NM_006895
 HNMT


histamine N-methyltransferase


chr14_-_37134050 1.285 FOXA1
forkhead box A1
chr3_-_11736946 1.277 NM_014667
 VGLL4
vestigial like 4 (Drosophila)
chr6_-_144427340 1.252 NM_001080951
NM_001080955
 PLAGL1

pleiomorphic adenoma gene-like 1

chr1_-_146543102 1.159


chr12_+_25096472 1.154 NM_006152
 LRMP
lymphoid-restricted membrane protein
chr22_-_35938298 1.141 NM_001051
 SSTR3
somatostatin receptor 3
chr2_+_17861266 1.112 NM_001105569
 MSGN1
mesogenin 1
chr12_-_56422120 1.043 NM_014770
 AGAP2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr14_-_37133927 1.015 FOXA1
forkhead box A1
chr12_+_25096755 1.012 LRMP
lymphoid-restricted membrane protein
chr11_-_18226743 1.010 NM_001127380
NM_030754
 SAA2

serum amyloid A2

chr17_-_55824083 1.004 USP32
ubiquitin specific peptidase 32

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 99 entries
enrichment   p-value GO term description
1.82 1.15e-02 GO:0031123 RNA 3'-end processing
1.77 3.91e-03 GO:0050851 antigen receptor-mediated signaling pathway
1.69 1.70e-02 GO:0002429 immune response-activating cell surface receptor signaling pathway
1.64 4.74e-02 GO:0000077 DNA damage checkpoint
1.56 3.86e-05 GO:0045321 leukocyte activation
1.51 3.99e-02 GO:0051251 positive regulation of lymphocyte activation
1.49 1.24e-09 GO:0016071 mRNA metabolic process
1.49 1.06e-04 GO:0008380 RNA splicing
1.49 2.60e-02 GO:0046649 lymphocyte activation
1.48 1.90e-05 GO:0012502 induction of programmed cell death
1.47 2.85e-05 GO:0006917 induction of apoptosis
1.47 4.41e-02 GO:0000375 RNA splicing, via transesterification reactions
1.47 4.48e-02 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
1.47 4.48e-02 GO:0000398 nuclear mRNA splicing, via spliceosome
1.46 1.15e-05 GO:0006397 mRNA processing
1.45 3.58e-03 GO:0032446 protein modification by small protein conjugation
1.45 4.03e-02 GO:0071156 regulation of cell cycle arrest
1.44 4.08e-04 GO:0070647 protein modification by small protein conjugation or removal
1.43 1.47e-02 GO:0007346 regulation of mitotic cell cycle
1.42 1.79e-02 GO:0010608 posttranscriptional regulation of gene expression

Gene overrepresentation in compartment category:

Showing 1 to 20 of 31 entries
enrichment   p-value GO term description
1.74 4.31e-02 GO:0030117 membrane coat
1.74 4.31e-02 GO:0048475 coated membrane
1.61 1.04e-06 GO:0016604 nuclear body
1.60 5.44e-03 GO:0016607 nuclear speck
1.36 8.35e-08 GO:0044451 nucleoplasm part
1.33 8.98e-05 GO:0005694 chromosome
1.32 3.63e-12 GO:0005654 nucleoplasm
1.28 8.20e-03 GO:0030529 ribonucleoprotein complex
1.27 7.05e-16 GO:0044428 nuclear part
1.27 6.01e-13 GO:0031981 nuclear lumen
1.25 5.04e-13 GO:0005829 cytosol
1.22 5.93e-11 GO:0031974 membrane-enclosed lumen
1.22 1.08e-10 GO:0043233 organelle lumen
1.22 4.79e-10 GO:0070013 intracellular organelle lumen
1.17 1.50e-10 GO:0032991 macromolecular complex
1.16 6.27e-07 GO:0043234 protein complex
1.15 2.31e-16 GO:0005634 nucleus
1.15 1.66e-05 GO:0043228 non-membrane-bounded organelle
1.15 1.66e-05 GO:0043232 intracellular non-membrane-bounded organelle
1.14 3.96e-13 GO:0044446 intracellular organelle part

Gene overrepresentation in function category:

Showing 1 to 12 of 12 entries
enrichment   p-value GO term description
1.48 4.41e-02 GO:0004721 phosphoprotein phosphatase activity
1.40 3.64e-02 GO:0019787 small conjugating protein ligase activity
1.38 4.25e-02 GO:0005096 GTPase activator activity
1.32 1.05e-06 GO:0003723 RNA binding
1.28 2.84e-02 GO:0060589 nucleoside-triphosphatase regulator activity
1.28 3.67e-02 GO:0030695 GTPase regulator activity
1.26 1.73e-03 GO:0019899 enzyme binding
1.20 2.05e-02 GO:0030234 enzyme regulator activity
1.17 1.61e-32 GO:0005515 protein binding
1.14 3.01e-03 GO:0000166 nucleotide binding
1.11 2.95e-03 GO:0003676 nucleic acid binding
1.07 2.38e-16 GO:0005488 binding