Motif ID: SPI1.p2

Z-value: 2.061


Transcription factors associated with SPI1.p2:

Gene SymbolEntrez IDGene Name
SPI1 6688 spleen focus forming virus (SFFV) proviral integration oncogene spi1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SPI1chr11_-_473566720.282.9e-01Click!


Activity profile for motif SPI1.p2.

activity profile for motif SPI1.p2


Sorted Z-values histogram for motif SPI1.p2

Sorted Z-values for motif SPI1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SPI1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_-_26395420 1.456 NM_001145168
NM_001145169
GPR113

G protein-coupled receptor 113

chr2_-_152663748 1.408 NM_000726
NM_001145798
CACNB4

calcium channel, voltage-dependent, beta 4 subunit

chr6_-_32265489 1.403 NM_002586
PBX2
pre-B-cell leukemia homeobox 2
chr20_-_32877029 1.393 NM_014071
NCOA6
nuclear receptor coactivator 6
chr6_-_33016561 1.382 NM_002118
HLA-DMB
major histocompatibility complex, class II, DM beta
chr2_-_148494732 1.366 NM_001190882
NM_001190879
NM_002552
NM_001190881
NM_181741
ORC4




origin recognition complex, subunit 4




chr14_-_37134191 1.295 NM_004496
FOXA1
forkhead box A1
chr2_+_138438277 1.290 NM_001024074
NM_001024075
NM_006895
HNMT


histamine N-methyltransferase


chr14_-_37134050 1.285 FOXA1
forkhead box A1
chr3_-_11736946 1.277 NM_014667
VGLL4
vestigial like 4 (Drosophila)
chr6_-_144427340 1.252 NM_001080951
NM_001080955
PLAGL1

pleiomorphic adenoma gene-like 1

chr1_-_146543102 1.159


chr12_+_25096472 1.154 NM_006152
LRMP
lymphoid-restricted membrane protein
chr22_-_35938298 1.141 NM_001051
SSTR3
somatostatin receptor 3
chr2_+_17861266 1.112 NM_001105569
MSGN1
mesogenin 1
chr12_-_56422120 1.043 NM_014770
AGAP2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr14_-_37133927 1.015 FOXA1
forkhead box A1
chr12_+_25096755 1.012 LRMP
lymphoid-restricted membrane protein
chr11_-_18226743 1.010 NM_001127380
NM_030754
SAA2

serum amyloid A2

chr17_-_55824083 1.004 USP32
ubiquitin specific peptidase 32
chr1_+_36462625 1.002 THRAP3
thyroid hormone receptor associated protein 3
chr16_-_87570716 0.997 NM_005187
CBFA2T3
core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr3_-_196644864 0.991 NM_012287
ACAP2
ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
chr2_-_152663454 0.974 NM_001005746
CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr17_+_53625084 0.962 NM_000502
EPX
eosinophil peroxidase
chr2_-_72228427 0.948 NM_019885
CYP26B1
cytochrome P450, family 26, subfamily B, polypeptide 1
chr16_+_66244314 0.944 RLTPR
RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing
chr1_-_183210155 0.944 FAM129A
family with sequence similarity 129, member A
chr20_+_21231921 0.939 NM_012255
XRN2
5'-3' exoribonuclease 2
chr6_+_31651319 0.938 NM_000594
TNF
tumor necrosis factor
chr1_-_146398501 0.925 LOC100286793
FLJ39739
hypothetical LOC100286793
hypothetical FLJ39739
chr11_+_85017269 0.921 NM_001193537
NM_001193538
NM_018480
TMEM126B


transmembrane protein 126B


chr20_+_42947754 0.918 NM_003404
NM_139323
YWHAB

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide

chr20_-_22512893 0.913 FOXA2
forkhead box A2
chr2_+_148495043 0.907 NM_018328
MBD5
methyl-CpG binding domain protein 5
chr14_+_31616196 0.904 NM_001030055
NM_001173
ARHGAP5

Rho GTPase activating protein 5

chr11_+_18244383 0.902 NM_000331
NM_001178006
NM_199161
SAA1


serum amyloid A1


chr2_-_55500450 0.881 NM_001135597
NM_018084
CCDC88A

coiled-coil domain containing 88A

chr11_+_120828058 0.879 NM_003105
SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr2_+_73973600 0.867 NM_001615
ACTG2
actin, gamma 2, smooth muscle, enteric
chr17_+_44643067 0.862 ABI3
ABI family, member 3
chr2_-_139254273 0.858 NM_007226
NXPH2
neurexophilin 2
chr2_+_73973640 0.857 ACTG2
actin, gamma 2, smooth muscle, enteric
chr6_+_21701942 0.845 NM_003107
SOX4
SRY (sex determining region Y)-box 4
chr10_-_5531401 0.836 NM_017422
CALML5
calmodulin-like 5
chr17_-_4113777 0.829 NM_016376
NM_020740
ANKFY1

ankyrin repeat and FYVE domain containing 1

chr2_+_190981257 0.817 NM_017694
MFSD6
major facilitator superfamily domain containing 6
chr9_-_26882713 0.810 NM_001167575
NM_024828
C9orf82

chromosome 9 open reading frame 82

chr5_+_49998528 0.806 NM_001178056
NM_024615
PARP8

poly (ADP-ribose) polymerase family, member 8

chr2_-_152664056 0.804 CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr17_-_24302450 0.803 PHF12
PHD finger protein 12
chr3_+_120495906 0.773 NM_020754
ARHGAP31
Rho GTPase activating protein 31
chr1_-_142535878 0.765 LOC100286793
FLJ39739
hypothetical LOC100286793
hypothetical FLJ39739
chr17_+_35046843 0.762 NM_001165937
NM_001165938
NM_006804
STARD3


StAR-related lipid transfer (START) domain containing 3


chr1_-_183210296 0.761 NM_052966
FAM129A
family with sequence similarity 129, member A
chr3_-_121295202 0.760 GSK3B
glycogen synthase kinase 3 beta
chr5_+_49998677 0.755 PARP8
poly (ADP-ribose) polymerase family, member 8
chr6_-_31658044 0.750 NM_002341
NM_009588
LTB

lymphotoxin beta (TNF superfamily, member 3)

chr3_-_107070400 0.749 NM_170662
CBLB
Cas-Br-M (murine) ecotropic retroviral transforming sequence b
chr2_-_201461945 0.744 NM_032472
NM_130906
PPIL3

peptidylprolyl isomerase (cyclophilin)-like 3

chr20_+_42947764 0.743 YWHAB
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
chr7_+_114350144 0.738 MDFIC
MyoD family inhibitor domain containing
chr14_-_22354389 0.738 SLC7A7
solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr6_+_30693464 0.734 NM_014046
MRPS18B
mitochondrial ribosomal protein S18B
chr2_-_74259308 0.733 NM_018221
MOBKL1B
MOB1, Mps One Binder kinase activator-like 1B (yeast)
chr1_+_159899528 0.723 NM_001002273
NM_001002274
NM_001002275
NM_001190828
NM_004001
FCGR2B




FCGR2C
Fc fragment of IgG, low affinity IIb, receptor (CD32)




Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
chr14_-_22358752 0.720 NM_001126106
SLC7A7
solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr2_-_148495642 0.719 NM_181742
ORC4
origin recognition complex, subunit 4
chr6_+_30702586 0.718 NM_024909
NM_001031722
NM_001190724
ATAT1


alpha tubulin acetyltransferase 1


chr11_+_63864263 0.718 NM_032251
CCDC88B
coiled-coil domain containing 88B
chr15_+_72687765 0.712 NM_003992
CLK3
CDC-like kinase 3
chr20_-_62208627 0.711 NM_005286
NPBWR2
neuropeptides B/W receptor 2
chr1_+_168767864 0.707 NM_001146039
NM_152281
GORAB

golgin, RAB6-interacting

chr16_+_28413421 0.702 NM_018690
APOBR
apolipoprotein B receptor
chr17_+_44642587 0.702 NM_001135186
NM_016428
ABI3

ABI family, member 3

chr2_-_180580024 0.699 NM_020943
CWC22
CWC22 spliceosome-associated protein homolog (S. cerevisiae)
chr7_-_104440707 0.691 LOC100216545
hypothetical LOC100216545
chr20_+_3661316 0.691 NM_001197327
NM_052970
HSPA12B

heat shock 70kD protein 12B

chr14_-_22354457 0.690 SLC7A7
solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr5_-_142795269 0.679 NM_001018074
NM_001018075
NM_001018077
NR3C1


nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)


chr20_-_22513050 0.678 NM_021784
FOXA2
forkhead box A2
chr1_+_239762179 0.677 NM_003679
KMO
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr12_+_53241365 0.673 NM_001165975
PDE1B
phosphodiesterase 1B, calmodulin-dependent
chr3_-_126576693 0.670 NM_021964
ZNF148
zinc finger protein 148
chr15_-_47125788 0.668 NM_001193489
NM_014701
SECISBP2L

SECIS binding protein 2-like

chr2_-_60634271 0.657 BCL11A
B-cell CLL/lymphoma 11A (zinc finger protein)
chr9_-_5997891 0.654 NM_001017969
KIAA2026
KIAA2026
chr1_-_52791309 0.652 NM_001009881
NM_015269
ZCCHC11

zinc finger, CCHC domain containing 11

chr14_-_30746577 0.652


chr2_+_48395271 0.638 NM_002158
FOXN2
forkhead box N2
chr1_+_32512298 0.636 NM_001042771
LCK
lymphocyte-specific protein tyrosine kinase
chr2_+_68445936 0.633 PLEK
pleckstrin
chr2_+_217206450 0.632 IGFBP2
insulin-like growth factor binding protein 2, 36kDa
chr4_+_39376058 0.632 NM_001111112
NM_001111113
NM_005339
UBE2K


ubiquitin-conjugating enzyme E2K (UBC1 homolog, yeast)


chr19_-_47328399 0.631 NM_002698
POU2F2
POU class 2 homeobox 2
chr15_-_21444085 0.629 NM_019066
MAGEL2
MAGE-like 2
chr3_-_15348811 0.626 SH3BP5
SH3-domain binding protein 5 (BTK-associated)
chr2_+_60836858 0.625 NM_022894
PAPOLG
poly(A) polymerase gamma
chr17_-_70901303 0.622 GRB2
growth factor receptor-bound protein 2
chr11_+_116520181 0.622 NM_001184746
NM_001184747
NM_001184748
NM_002572
PAFAH1B2



platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)



chr9_-_99740243 0.615 NM_197978
HEMGN
hemogen
chr12_+_118590039 0.614 NM_006253
PRKAB1
protein kinase, AMP-activated, beta 1 non-catalytic subunit
chr4_-_84595967 0.612 NM_133636
HELQ
helicase, POLQ-like
chr7_+_107171809 0.609 CBLL1
Cas-Br-M (murine) ecotropic retroviral transforming sequence-like 1
chr5_+_176951802 0.608 NM_017510
TMED9
transmembrane emp24 protein transport domain containing 9
chr14_-_30746431 0.608 NM_015382
HECTD1
HECT domain containing 1
chr11_+_72658586 0.599 NM_176798
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr6_+_152053323 0.595 NM_001122742
ESR1
estrogen receptor 1
chr20_+_30329096 0.594 NM_004798
KIF3B
kinesin family member 3B
chr19_-_10311262 0.591 NM_002162
ICAM3
intercellular adhesion molecule 3
chr3_-_131948202 0.591 NM_014602
PIK3R4
phosphoinositide-3-kinase, regulatory subunit 4
chr12_+_27568311 0.591 NM_001198915
NM_001198916
NM_003622
NM_177444
PPFIBP1



PTPRF interacting protein, binding protein 1 (liprin beta 1)



chr16_-_69030421 0.588 NM_006927
ST3GAL2
ST3 beta-galactoside alpha-2,3-sialyltransferase 2
chr11_+_65026382 0.583


chr20_+_762355 0.582 NM_001042353
FAM110A
family with sequence similarity 110, member A
chr11_-_101828563 0.581 NM_052932
TMEM123
transmembrane protein 123
chr15_+_83724743 0.579 NM_006738
NM_007200
AKAP13

A kinase (PRKA) anchor protein 13

chr1_+_36462583 0.578 NM_005119
THRAP3
thyroid hormone receptor associated protein 3
chr12_+_118911859 0.578 NM_207311
CCDC64
coiled-coil domain containing 64
chr14_-_23090606 0.577 NM_033400
ZFHX2
zinc finger homeobox 2
chr6_-_8047731 0.575 NM_001135650
NM_004280
EEF1E1

eukaryotic translation elongation factor 1 epsilon 1

chr12_-_53664722 0.575 NM_001136030
KIAA0748
KIAA0748
chr6_+_57290357 0.572 NM_000947
PRIM2
primase, DNA, polypeptide 2 (58kDa)
chr4_+_84596141 0.572 NM_016067
MRPS18C
mitochondrial ribosomal protein S18C
chr20_-_35318690 0.570 NM_001184731
NM_021081
GHRH

growth hormone releasing hormone

chr14_-_34413831 0.569 BAZ1A
bromodomain adjacent to zinc finger domain, 1A
chr1_+_9634368 0.566 NM_005026
PIK3CD
phosphoinositide-3-kinase, catalytic, delta polypeptide
chr17_-_40655347 0.564 LOC339192
hypothetical LOC339192
chr2_+_85051687 0.564 NM_020122
KCMF1
potassium channel modulatory factor 1
chr6_-_125664913 0.563 NM_016063
HDDC2
HD domain containing 2
chr17_+_25828546 0.562 NM_001007024
NM_001007025
NM_004871
GOSR1


golgi SNAP receptor complex member 1


chr7_+_128651976 0.561 NM_001130720
NM_015328
AHCYL2

adenosylhomocysteinase-like 2

chr12_+_60940404 0.560 NM_006313
USP15
ubiquitin specific peptidase 15
chr2_-_231498184 0.560 NM_005683
GPR55
G protein-coupled receptor 55
chr11_-_46099531 0.554 NM_001101802
NM_016621
PHF21A

PHD finger protein 21A

chr20_+_3138055 0.551 NM_033453
NM_181493
ITPA

inosine triphosphatase (nucleoside triphosphate pyrophosphatase)

chr22_-_30018329 0.550 NM_001135911
NM_052880
PIK3IP1

phosphoinositide-3-kinase interacting protein 1

chr5_+_140454382 0.549 NM_018936
PCDHB2
protocadherin beta 2
chr4_+_71986927 0.547 NM_173468
MOBKL1A
MOB1, Mps One Binder kinase activator-like 1A (yeast)
chr2_-_202811459 0.545 NM_001005781
NM_001005782
NM_003352
SUMO1


SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)


chr17_-_44642934 0.544 NM_001198754
GNGT2
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
chr10_+_73703682 0.540 NM_019058
DDIT4
DNA-damage-inducible transcript 4
chr16_-_21197072 0.539 CRYM
crystallin, mu
chr14_-_22354851 0.538 NM_001126105
NM_003982
SLC7A7

solute carrier family 7 (cationic amino acid transporter, y+ system), member 7

chr17_-_34860840 0.538 NM_004774
MED1
mediator complex subunit 1
chr6_+_73388713 0.536 KCNQ5
potassium voltage-gated channel, KQT-like subfamily, member 5
chr6_-_32299757 0.536 NM_004557
NOTCH4
notch 4
chr2_-_174537021 0.535 NM_001017371
SP3
Sp3 transcription factor
chr14_+_22305570 0.534 NM_005015
OXA1L
oxidase (cytochrome c) assembly 1-like
chr8_-_15140162 0.532 NM_139167
SGCZ
sarcoglycan, zeta
chr20_+_16658608 0.529 NM_003092
NM_198220
SNRPB2

small nuclear ribonucleoprotein polypeptide B

chr6_-_56816403 0.526 DST
dystonin
chr2_-_88136362 0.524 NM_016618
KRCC1
lysine-rich coiled-coil 1
chrX_-_17789276 0.523 NM_001172732
NM_001172739
NM_001172743
NM_021785
RAI2



retinoic acid induced 2



chr6_+_31690957 0.521 NM_004847
NM_001623
AIF1

allograft inflammatory factor 1

chr2_+_217071764 0.520 NM_000998
RPL37A
ribosomal protein L37a
chr6_-_119137923 0.519 NM_001178035
C6orf204
chromosome 6 open reading frame 204
chr18_+_30875297 0.519 NM_014268
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr18_-_50004770 0.518 MBD2
methyl-CpG binding domain protein 2
chr15_-_41381744 0.518 NM_052955
TGM7
transglutaminase 7
chr2_-_88136394 0.513 KRCC1
lysine-rich coiled-coil 1
chr2_-_197883569 0.512 ANKRD44
ankyrin repeat domain 44
chr2_+_227737524 0.511 NM_000091
COL4A3
collagen, type IV, alpha 3 (Goodpasture antigen)
chr4_+_689529 0.507 NM_006315
PCGF3
polycomb group ring finger 3
chr2_-_122210873 0.507 NM_032390
MKI67IP
MKI67 (FHA domain) interacting nucleolar phosphoprotein
chr17_+_40655060 0.507 NM_005892
FMNL1
formin-like 1
chr17_-_31441390 0.507 NM_002983
CCL3
chemokine (C-C motif) ligand 3
chr16_-_73292188 0.502 NM_001142497
NM_152649
MLKL

mixed lineage kinase domain-like

chr14_-_38709161 0.502 NM_001079537
NM_177452
TRAPPC6B

trafficking protein particle complex 6B

chr8_+_21956335 0.501 NM_003867
FGF17
fibroblast growth factor 17
chr3_-_150858274 0.501 NM_001168280
NM_015472
WWTR1

WW domain containing transcription regulator 1

chr2_+_71412348 0.500 NM_001014972
NM_014497
ZNF638

zinc finger protein 638

chr2_+_218698980 0.500 NM_001557
CXCR2
chemokine (C-X-C motif) receptor 2
chr2_+_85051942 0.499 KCMF1
potassium channel modulatory factor 1
chr19_-_59418739 0.499 NM_001081450
NM_006864
LILRB3

leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3

chr16_+_29725311 0.496 NM_001042539
NM_002383
MAZ

MYC-associated zinc finger protein (purine-binding transcription factor)

chr15_+_87919744 0.495 NM_152259
C15orf42
chromosome 15 open reading frame 42
chr2_+_187163232 0.494 ITGAV
integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)
chr2_+_218790364 0.494 NM_005731
ARPC2
actin related protein 2/3 complex, subunit 2, 34kDa
chr12_+_56374004 0.494 NM_001017956
NM_001017957
NM_001017958
NM_006812
OS9



osteosarcoma amplified 9, endoplasmic reticulum lectin



chr7_+_104959767 0.494 NM_021930
RINT1
RAD50 interactor 1
chr4_+_56509793 0.494 NM_025009
CEP135
centrosomal protein 135kDa
chr1_+_233558863 0.492 GGPS1
geranylgeranyl diphosphate synthase 1
chr11_+_57066689 0.492 NM_001105565
SMTNL1
smoothelin-like 1
chr12_+_48003237 0.490 NM_001100620
NM_005480
TROAP

trophinin associated protein (tastin)

chr6_+_31648071 0.487 NM_000595
LTA
lymphotoxin alpha (TNF superfamily, member 1)
chr2_+_219780192 0.487 ZFAND2B
zinc finger, AN1-type domain 2B
chr2_+_46779827 0.487 NM_144949
SOCS5
suppressor of cytokine signaling 5
chr16_+_21518633 0.487 METTL9
methyltransferase like 9
chr16_-_87244896 0.486 NM_000101
CYBA
cytochrome b-245, alpha polypeptide
chr16_+_56134037 0.485 GPR114
G protein-coupled receptor 114
chr16_+_30112707 0.485 NM_001014999
NM_001015000
NM_024044
NM_178044
SLX1A-SULT1A3
SLX1A

SLX1B

SLX1A-SULT1A3 read-through transcript
SLX1 structure-specific endonuclease subunit homolog A (S. cerevisiae)

SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)

chr16_-_21197138 0.484 CRYM
crystallin, mu
chr6_-_27548438 0.483 NM_007149
ZNF184
zinc finger protein 184
chr2_-_153282104 0.481 NM_017892
PRPF40A
PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)
chr10_-_75080784 0.481 NM_024875
SYNPO2L
synaptopodin 2-like
chr16_-_56789142 0.480 NM_001896
CSNK2A2
casein kinase 2, alpha prime polypeptide
chr10_+_124310170 0.480 NM_004406
NM_007329
NM_017579
DMBT1


deleted in malignant brain tumors 1


chr2_-_20413838 0.478 PUM2
pumilio homolog 2 (Drosophila)
chr2_+_32244406 0.478 NM_001193513
NM_001193514
NM_001193515
NM_017964
SLC30A6



solute carrier family 30 (zinc transporter), member 6




Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.21 1.19e-20 GO:0044260 cellular macromolecule metabolic process
1.18 3.49e-18 GO:0043170 macromolecule metabolic process
1.07 1.69e-13 GO:0009987 cellular process
1.13 1.33e-12 GO:0044237 cellular metabolic process
1.29 2.92e-12 GO:0016070 RNA metabolic process
1.12 1.10e-11 GO:0044238 primary metabolic process
1.24 2.32e-11 GO:0090304 nucleic acid metabolic process
1.26 7.79e-11 GO:0010467 gene expression
1.22 3.38e-10 GO:0048522 positive regulation of cellular process
1.22 3.91e-10 GO:0044267 cellular protein metabolic process
1.20 1.00e-09 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.49 1.24e-09 GO:0016071 mRNA metabolic process
1.20 1.44e-09 GO:0048518 positive regulation of biological process
1.17 3.78e-09 GO:0071840 cellular component organization or biogenesis
1.17 4.55e-09 GO:0016043 cellular component organization
1.10 5.44e-09 GO:0008152 metabolic process
1.18 2.19e-07 GO:0071842 cellular component organization at cellular level
1.39 2.70e-07 GO:0006396 RNA processing
1.18 5.69e-07 GO:0071841 cellular component organization or biogenesis at cellular level
1.16 1.05e-06 GO:0019538 protein metabolic process
1.38 2.09e-06 GO:0051726 regulation of cell cycle
1.15 2.59e-06 GO:0034641 cellular nitrogen compound metabolic process
1.15 3.26e-06 GO:0006807 nitrogen compound metabolic process
1.08 3.93e-06 GO:0050789 regulation of biological process
1.21 4.39e-06 GO:0006464 protein modification process
1.09 7.33e-06 GO:0050794 regulation of cellular process
1.28 8.37e-06 GO:0043067 regulation of programmed cell death
1.20 8.38e-06 GO:0048583 regulation of response to stimulus
1.28 8.68e-06 GO:0042981 regulation of apoptosis
1.46 1.15e-05 GO:0006397 mRNA processing
1.48 1.90e-05 GO:0012502 induction of programmed cell death
1.21 2.30e-05 GO:0006996 organelle organization
1.27 2.31e-05 GO:0010941 regulation of cell death
1.19 2.39e-05 GO:0043412 macromolecule modification
1.27 2.50e-05 GO:0032268 regulation of cellular protein metabolic process
1.47 2.85e-05 GO:0006917 induction of apoptosis
1.13 2.88e-05 GO:0019222 regulation of metabolic process
1.26 3.81e-05 GO:0051246 regulation of protein metabolic process
1.56 3.86e-05 GO:0045321 leukocyte activation
1.07 4.64e-05 GO:0065007 biological regulation
1.23 5.03e-05 GO:0009966 regulation of signal transduction
1.17 5.99e-05 GO:0048519 negative regulation of biological process
1.25 8.49e-05 GO:0010604 positive regulation of macromolecule metabolic process
1.49 1.06e-04 GO:0008380 RNA splicing
1.30 1.32e-04 GO:0031399 regulation of protein modification process
1.26 2.05e-04 GO:0007049 cell cycle
1.37 2.08e-04 GO:0043065 positive regulation of apoptosis
1.37 2.24e-04 GO:0043068 positive regulation of programmed cell death
1.29 3.37e-04 GO:0046907 intracellular transport
1.36 3.82e-04 GO:0010942 positive regulation of cell death
1.33 4.03e-04 GO:0009057 macromolecule catabolic process
1.44 4.08e-04 GO:0070647 protein modification by small protein conjugation or removal
1.13 4.30e-04 GO:0060255 regulation of macromolecule metabolic process
1.23 5.43e-04 GO:0031325 positive regulation of cellular metabolic process
1.12 6.27e-04 GO:0031323 regulation of cellular metabolic process
1.35 7.27e-04 GO:0044265 cellular macromolecule catabolic process
1.22 8.81e-04 GO:0009893 positive regulation of metabolic process
1.16 9.30e-04 GO:0048523 negative regulation of cellular process
1.26 1.14e-03 GO:0016265 death
1.22 1.16e-03 GO:0002376 immune system process
1.21 1.19e-03 GO:0051641 cellular localization
1.26 1.41e-03 GO:0008219 cell death
1.23 1.42e-03 GO:0051649 establishment of localization in cell
1.24 1.64e-03 GO:0006793 phosphorus metabolic process
1.24 1.64e-03 GO:0006796 phosphate metabolic process
1.12 1.91e-03 GO:0080090 regulation of primary metabolic process
1.18 2.28e-03 GO:0023051 regulation of signaling
1.20 2.66e-03 GO:0035556 intracellular signal transduction
1.45 3.58e-03 GO:0032446 protein modification by small protein conjugation
1.77 3.91e-03 GO:0050851 antigen receptor-mediated signaling pathway
1.33 4.38e-03 GO:0001775 cell activation
1.39 4.91e-03 GO:0016568 chromatin modification
1.28 4.98e-03 GO:0002682 regulation of immune system process
1.27 6.03e-03 GO:0006915 apoptosis
1.17 6.07e-03 GO:0009059 macromolecule biosynthetic process
1.27 7.79e-03 GO:0012501 programmed cell death
1.33 8.67e-03 GO:0006325 chromatin organization
1.22 9.54e-03 GO:0022607 cellular component assembly
1.82 1.15e-02 GO:0031123 RNA 3'-end processing
1.20 1.19e-02 GO:0044085 cellular component biogenesis
1.17 1.29e-02 GO:0034645 cellular macromolecule biosynthetic process
1.43 1.47e-02 GO:0007346 regulation of mitotic cell cycle
1.36 1.56e-02 GO:0051056 regulation of small GTPase mediated signal transduction
1.69 1.70e-02 GO:0002429 immune response-activating cell surface receptor signaling pathway
1.42 1.79e-02 GO:0010608 posttranscriptional regulation of gene expression
1.35 2.06e-02 GO:0032270 positive regulation of cellular protein metabolic process
1.34 2.51e-02 GO:0051247 positive regulation of protein metabolic process
1.49 2.60e-02 GO:0046649 lymphocyte activation
1.32 3.12e-02 GO:0002684 positive regulation of immune system process
1.36 3.31e-02 GO:0010564 regulation of cell cycle process
1.51 3.99e-02 GO:0051251 positive regulation of lymphocyte activation
1.45 4.03e-02 GO:0071156 regulation of cell cycle arrest
1.19 4.36e-02 GO:0050790 regulation of catalytic activity
1.47 4.41e-02 GO:0000375 RNA splicing, via transesterification reactions
1.47 4.48e-02 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
1.47 4.48e-02 GO:0000398 nuclear mRNA splicing, via spliceosome
1.27 4.67e-02 GO:0051276 chromosome organization
1.25 4.72e-02 GO:0042325 regulation of phosphorylation
1.64 4.74e-02 GO:0000077 DNA damage checkpoint

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.09 4.11e-27 GO:0005622 intracellular
1.09 5.26e-26 GO:0044424 intracellular part
1.15 2.31e-16 GO:0005634 nucleus
1.27 7.05e-16 GO:0044428 nuclear part
1.09 1.96e-15 GO:0043229 intracellular organelle
1.10 2.45e-15 GO:0005737 cytoplasm
1.09 3.62e-15 GO:0043226 organelle
1.10 2.42e-14 GO:0043231 intracellular membrane-bounded organelle
1.10 4.12e-14 GO:0043227 membrane-bounded organelle
1.14 3.96e-13 GO:0044446 intracellular organelle part
1.25 5.04e-13 GO:0005829 cytosol
1.27 6.01e-13 GO:0031981 nuclear lumen
1.13 9.58e-13 GO:0044422 organelle part
1.32 3.63e-12 GO:0005654 nucleoplasm
1.22 5.93e-11 GO:0031974 membrane-enclosed lumen
1.22 1.08e-10 GO:0043233 organelle lumen
1.17 1.50e-10 GO:0032991 macromolecular complex
1.22 4.79e-10 GO:0070013 intracellular organelle lumen
1.10 8.09e-08 GO:0044444 cytoplasmic part
1.36 8.35e-08 GO:0044451 nucleoplasm part
1.16 6.27e-07 GO:0043234 protein complex
1.61 1.04e-06 GO:0016604 nuclear body
1.15 1.66e-05 GO:0043228 non-membrane-bounded organelle
1.15 1.66e-05 GO:0043232 intracellular non-membrane-bounded organelle
1.33 8.98e-05 GO:0005694 chromosome
1.02 3.33e-04 GO:0044464 cell part
1.02 3.59e-04 GO:0005623 cell
1.60 5.44e-03 GO:0016607 nuclear speck
1.28 8.20e-03 GO:0030529 ribonucleoprotein complex
1.74 4.31e-02 GO:0030117 membrane coat
1.74 4.31e-02 GO:0048475 coated membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.17 1.61e-32 GO:0005515 protein binding
1.07 2.38e-16 GO:0005488 binding
1.32 1.05e-06 GO:0003723 RNA binding
1.26 1.73e-03 GO:0019899 enzyme binding
1.11 2.95e-03 GO:0003676 nucleic acid binding
1.14 3.01e-03 GO:0000166 nucleotide binding
1.20 2.05e-02 GO:0030234 enzyme regulator activity
1.28 2.84e-02 GO:0060589 nucleoside-triphosphatase regulator activity
1.40 3.64e-02 GO:0019787 small conjugating protein ligase activity
1.28 3.67e-02 GO:0030695 GTPase regulator activity
1.38 4.25e-02 GO:0005096 GTPase activator activity
1.48 4.41e-02 GO:0004721 phosphoprotein phosphatase activity