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• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: SPIB.p2

Z-value: 1.487

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr17_+_64922420	1.990	NM_002758	MAP2K6	mitogen-activated protein kinase kinase 6
chr6_-_159386007	1.460	NM_054114 NM_138810 NM_152133	TAGAP	T-cell activation RhoGTPase activating protein
chr17_+_37693090	1.069	NM_003152	STAT5A	signal transducer and activator of transcription 5A
chr6_+_130381408	1.064	NM_001007102 NM_032438	L3MBTL3	l(3)mbt-like 3 (Drosophila)
chr2_+_183651531	1.041	NM_001142314 NM_080876	DUSP19	dual specificity phosphatase 19
chr6_-_32742265	1.037	NM_002123	HLA-DQB1	major histocompatibility complex, class II, DQ beta 1
chr12_+_4253143	1.010	NM_001759	CCND2	cyclin D2
chr14_+_22915772	1.006	NM_001037288 NM_138460	CMTM5	CKLF-like MARVEL transmembrane domain containing 5
chr17_-_53847937	0.977		RNF43	ring finger protein 43
chr2_+_102401580	0.976	NM_003853	IL18RAP	interleukin 18 receptor accessory protein
chr14_-_22658078	0.969	NM_001805	CEBPE	CCAAT/enhancer binding protein (C/EBP), epsilon
chr2_-_175207521	0.894	NM_003387	WIPF1	WAS/WASL interacting protein family, member 1
chr14_-_22127902	0.858		DAD1	defender against cell death 1
chr16_-_30841938	0.813		NCRNA00095	non-protein coding RNA 95
chr7_-_104440707	0.803		LOC100216545	hypothetical LOC100216545
chr2_-_55349818	0.800	NM_001005369	MTIF2	mitochondrial translational initiation factor 2
chr17_+_35046843	0.784	NM_001165937 NM_001165938 NM_006804	STARD3	StAR-related lipid transfer (START) domain containing 3
chr11_+_65026382	0.758
chr17_+_44643067	0.757		ABI3	ABI family, member 3
chr16_-_83703496	0.749	NM_198491	FAM92B	family with sequence similarity 92, member B
chr14_-_21074875	0.748	NM_005407	SALL2	sal-like 2 (Drosophila)
chr5_-_138822475	0.703	NM_001077693	ECSCR	endothelial cell-specific chemotaxis regulator
chr6_-_56816403	0.696		DST	dystonin
chr12_+_97513644	0.693		SLC25A3	solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3
chr2_+_217071764	0.679	NM_000998	RPL37A	ribosomal protein L37a
chr2_+_138438277	0.674	NM_001024074 NM_001024075 NM_006895	HNMT	histamine N-methyltransferase
chr12_-_120725210	0.671		LOC338799	hypothetical LOC338799
chr2_-_55349851	0.658	NM_002453	MTIF2	mitochondrial translational initiation factor 2
chr17_-_44642934	0.656	NM_001198754	GNGT2	guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
chr6_+_12398514	0.644	NM_001168319 NM_001955	EDN1	endothelin 1
chr2_+_220170804	0.640	NM_052902	STK11IP	serine/threonine kinase 11 interacting protein
chr4_+_109761170	0.638	NM_000995 NM_033625	RPL34	ribosomal protein L34
chr12_+_118590039	0.627	NM_006253	PRKAB1	protein kinase, AMP-activated, beta 1 non-catalytic subunit
chr20_-_48686832	0.624	NM_080829	FAM65C	family with sequence similarity 65, member C
chr11_-_95715976	0.617	NM_032427	MAML2	mastermind-like 2 (Drosophila)
chr5_+_132237253	0.617	NM_052971	LEAP2	liver expressed antimicrobial peptide 2
chr6_+_31651319	0.616	NM_000594	TNF	tumor necrosis factor
chr20_-_48980858	0.609	NM_015339 NM_181442	ADNP	activity-dependent neuroprotector homeobox
chr17_-_70901303	0.608		GRB2	growth factor receptor-bound protein 2
chr5_-_71838875	0.602	NM_152625	ZNF366	zinc finger protein 366
chr2_-_213723298	0.597	NM_016260	IKZF2	IKAROS family zinc finger 2 (Helios)
chr6_+_114285209	0.581	NM_002356	MARCKS	myristoylated alanine-rich protein kinase C substrate
chr6_-_47030492	0.575	NM_015234	GPR116	G protein-coupled receptor 116
chr17_+_55269974	0.573
chr2_+_48521411	0.571	NM_001135629 NM_001193475 NM_152994	KLRAQ1	KLRAQ motif containing 1
chr20_-_50241581	0.568		ZFP64	zinc finger protein 64 homolog (mouse)
chr16_+_28413421	0.565	NM_018690	APOBR	apolipoprotein B receptor
chr17_-_53282376	0.564	NM_016070	MRPS23	mitochondrial ribosomal protein S23
chr2_+_149118791	0.560		EPC2	enhancer of polycomb homolog 2 (Drosophila)
chr2_+_217206450	0.542		IGFBP2	insulin-like growth factor binding protein 2, 36kDa
chr14_-_22891865	0.540	NM_016609	SLC22A17	solute carrier family 22, member 17
chr6_+_57290357	0.535	NM_000947	PRIM2	primase, DNA, polypeptide 2 (58kDa)
chr8_-_92122219	0.534	NM_018710	TMEM55A	transmembrane protein 55A
chr20_-_13567529	0.533	NM_017714	TASP1	taspase, threonine aspartase, 1
chr15_+_79376295	0.527	NM_004513	IL16	interleukin 16 (lymphocyte chemoattractant factor)
chr14_-_22127954	0.525	NM_001344	DAD1	defender against cell death 1
chr14_+_23937766	0.524	NM_025081	NYNRIN	NYN domain and retroviral integrase containing
chr16_+_11978002	0.520	NM_032167	RUNDC2A	RUN domain containing 2A
chr2_+_149119029	0.519	NM_015630	EPC2	enhancer of polycomb homolog 2 (Drosophila)
chr7_+_128651976	0.514	NM_001130720 NM_015328	AHCYL2	adenosylhomocysteinase-like 2
chr2_-_175754366	0.511	NM_001002258 NM_001190329 NM_001689	ATP5G3	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)
chr8_-_120914233	0.509	NM_003184	TAF2	TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa
chr6_+_21701942	0.503	NM_003107	SOX4	SRY (sex determining region Y)-box 4
chr14_-_21049204	0.499	NM_019852	METTL3	methyltransferase like 3
chr6_-_117096594	0.497	NM_145062	ZUFSP	zinc finger with UFM1-specific peptidase domain
chr4_-_174557191	0.493	NM_007281	SCRG1	stimulator of chondrogenesis 1
chr11_+_8660913	0.492		RPL27A	ribosomal protein L27a
chr3_+_139200347	0.491	NM_001002026	CLDN18	claudin 18
chr6_-_31007905	0.490	NM_205854	SFTA2	surfactant associated 2
chr14_-_22549168	0.489	NM_001130706 NM_001130708 NM_021944	C14orf93	chromosome 14 open reading frame 93
chr9_-_129580732	0.485	NM_170600	SH2D3C	SH2 domain containing 3C
chr2_+_113601608	0.480	NM_173842	IL1RN	interleukin 1 receptor antagonist
chr20_+_29598848	0.478		HM13	histocompatibility (minor) 13
chr12_+_91620749	0.476	NM_001037671 NM_001178097	C12orf74	chromosome 12 open reading frame 74
chr12_-_6615348	0.474	NM_020400	LPAR5	lysophosphatidic acid receptor 5
chr2_+_113601616	0.473		IL1RN	interleukin 1 receptor antagonist
chr8_+_82807218	0.472	NM_152284	CHMP4C	chromatin modifying protein 4C
chr12_+_92595281	0.471	NM_003805	CRADD	CASP2 and RIPK1 domain containing adaptor with death domain
chr1_+_9634368	0.471	NM_005026	PIK3CD	phosphoinositide-3-kinase, catalytic, delta polypeptide
chr20_+_30160952	0.468	NM_014742	TM9SF4	transmembrane 9 superfamily protein member 4
chr11_+_63864263	0.466	NM_032251	CCDC88B	coiled-coil domain containing 88B
chr12_+_56374004	0.466	NM_001017956 NM_001017957 NM_001017958 NM_006812	OS9	osteosarcoma amplified 9, endoplasmic reticulum lectin
chr8_-_92151363	0.462
chr2_+_85619802	0.458		MAT2A	methionine adenosyltransferase II, alpha
chr2_+_29057667	0.457	NM_199280	FAM179A	family with sequence similarity 179, member A
chr20_-_49008445	0.447	NM_003859	DPM1	dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit
chr2_-_202811459	0.445	NM_001005781 NM_001005782 NM_003352	SUMO1	SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)
chr11_-_33847507	0.442		LMO2	LIM domain only 2 (rhombotin-like 1)
chr17_+_63252704	0.440		BPTF	bromodomain PHD finger transcription factor
chr2_-_74259308	0.438	NM_018221	MOBKL1B	MOB1, Mps One Binder kinase activator-like 1B (yeast)
chr8_+_64243741	0.433		YTHDF3	YTH domain family, member 3
chr14_-_21172837	0.432	NM_001005466	OR10G2	olfactory receptor, family 10, subfamily G, member 2
chr6_+_31662454	0.431	NM_205837	LST1	leukocyte specific transcript 1
chr7_+_104959767	0.431	NM_021930	RINT1	RAD50 interactor 1
chr16_-_29781842	0.425	NM_006319	CDIPT	CDP-diacylglycerol--inositol 3-phosphatidyltransferase
chr11_+_101693403	0.423	NM_001165 NM_182962	BIRC3	baculoviral IAP repeat containing 3
chr17_-_41625921	0.423	NM_001193466	KIAA1267	KIAA1267
chr12_-_15005761	0.420	NM_001175	ARHGDIB	Rho GDP dissociation inhibitor (GDI) beta
chr6_-_56824371	0.417		DST	dystonin
chr7_+_141084591	0.414	NM_003143	SSBP1	single-stranded DNA binding protein 1
chr14_+_28311740	0.413		C14orf23	chromosome 14 open reading frame 23
chr19_-_47623340	0.413	NM_005357	LIPE	lipase, hormone-sensitive
chr8_-_57149588	0.413	NM_001023 NM_001146227	RPS20	ribosomal protein S20
chr6_+_31661934	0.411	NM_205838 NM_205839	LST1	leukocyte specific transcript 1
chr16_-_15644465	0.411	NM_001184998 NM_001184999 NM_014647	KIAA0430	KIAA0430
chr5_+_61910318	0.411	NM_181506	LRRC70	leucine rich repeat containing 70
chr16_-_3246587	0.410	NM_000243 NM_001198536	MEFV	Mediterranean fever
chr16_+_15644624	0.407	NM_001143979	NDE1	nudE nuclear distribution gene E homolog 1 (A. nidulans)
chr16_+_24696069	0.407		TNRC6A	trinucleotide repeat containing 6A
chr1_+_159462456	0.406	NM_032174	TOMM40L	translocase of outer mitochondrial membrane 40 homolog (yeast)-like
chr5_-_158567411	0.406	NM_144726	RNF145	ring finger protein 145
chr12_-_56157898	0.404	NM_001080156	ARHGAP9	Rho GTPase activating protein 9
chr14_-_20969706	0.403	NM_001170629	CHD8	chromodomain helicase DNA binding protein 8
chr6_-_116488458	0.402	NM_002031	FRK	fyn-related kinase
chr1_+_154390939	0.401		SEMA4A	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr1_-_205210567	0.401	NM_001122979 NM_001170631 NM_032029	FCAMR	Fc receptor, IgA, IgM, high affinity
chr7_+_139175420	0.400	NM_001061 NM_001166253 NM_030984	TBXAS1	thromboxane A synthase 1 (platelet)
chr4_-_103968104	0.400	NM_003340 NM_181886 NM_181888 NM_181889	UBE2D3	ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)
chr20_+_30161173	0.399		TM9SF4	transmembrane 9 superfamily protein member 4
chr2_-_27147995	0.399	NM_001134693	OST4	oligosaccharyltransferase 4 homolog (S. cerevisiae)
chr2_-_206659140	0.399	NM_017759	INO80D	INO80 complex subunit D
chr2_-_190893015	0.397	NM_014362 NM_198047	HIBCH	3-hydroxyisobutyryl-CoA hydrolase
chr11_+_74788200	0.395	NM_001005	RPS3	ribosomal protein S3
chr6_-_119137923	0.392	NM_001178035	C6orf204	chromosome 6 open reading frame 204
chr16_-_87460514	0.391	NM_001080487	PABPN1L	poly(A) binding protein, nuclear 1-like (cytoplasmic)
chr1_-_171441234	0.390		TNFSF4	tumor necrosis factor (ligand) superfamily, member 4
chr20_-_50241930	0.387	NM_018197 NM_022088 NM_199426 NM_199427	ZFP64	zinc finger protein 64 homolog (mouse)
chr11_+_65027721	0.387
chr2_+_183651713	0.382		DUSP19	dual specificity phosphatase 19
chr6_+_15354278	0.382	NM_004973	JARID2	jumonji, AT rich interactive domain 2
chr7_+_102775309	0.381	NM_002803	PSMC2	proteasome (prosome, macropain) 26S subunit, ATPase, 2
chr2_-_178125680	0.380	NM_152517	TTC30B	tetratricopeptide repeat domain 30B
chr6_-_34963565	0.378	NM_005643	TAF11	TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa
chr1_-_220829704	0.378	NM_005681 NM_139352	TAF1A	TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa
chr2_-_96174865	0.374	NM_004418	DUSP2	dual specificity phosphatase 2
chr6_-_28327980	0.374	NM_019110	ZKSCAN4	zinc finger with KRAB and SCAN domains 4
chr22_+_29333069	0.373	NM_000355 NM_001184726	TCN2	transcobalamin II
chr14_-_24047261	0.370	NM_001836	CMA1	chymase 1, mast cell
chr20_+_47096280	0.368		CSE1L	CSE1 chromosome segregation 1-like (yeast)
chr14_-_20975241	0.366	NM_020920	CHD8	chromodomain helicase DNA binding protein 8
chr18_+_30875297	0.366	NM_014268	MAPRE2	microtubule-associated protein, RP/EB family, member 2
chr5_-_139402909	0.365		NRG2	neuregulin 2
chr5_+_180514548	0.365	NM_206880	OR2V2	olfactory receptor, family 2, subfamily V, member 2
chr5_+_139485703	0.363	NM_001007189	C5orf53	chromosome 5 open reading frame 53
chr7_+_99052489	0.362	NM_145115	ZNF498	zinc finger protein 498
chr6_-_32265489	0.362	NM_002586	PBX2	pre-B-cell leukemia homeobox 2
chr2_-_61551403	0.359		USP34	ubiquitin specific peptidase 34
chr12_-_46438447	0.358	NM_001098532 NM_006105	RAPGEF3	Rap guanine nucleotide exchange factor (GEF) 3
chr17_+_44642587	0.358	NM_001135186 NM_016428	ABI3	ABI family, member 3
chr5_+_143171918	0.357	NM_021182	HMHB1	histocompatibility (minor) HB-1
chr17_+_35718948	0.357	NM_000964	RARA	retinoic acid receptor, alpha
chr22_+_35586950	0.357	NM_000631 NM_013416	NCF4	neutrophil cytosolic factor 4, 40kDa
chr6_+_43136159	0.355	NM_201522	KLC4	kinesin light chain 4
chr6_+_31647854	0.353	NM_001159740	LTA	lymphotoxin alpha (TNF superfamily, member 1)
chr16_+_24459173	0.351		RBBP6	retinoblastoma binding protein 6
chr1_-_116184846	0.349	NM_001111061	NHLH2	nescient helix loop helix 2
chr3_+_87359088	0.349	NM_014043	CHMP2B	chromatin modifying protein 2B
chr9_-_6005602	0.349	NM_012416	RANBP6	RAN binding protein 6
chr17_+_35097851	0.349	NM_001005862	ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)
chr2_+_85619797	0.349	NM_005911	MAT2A	methionine adenosyltransferase II, alpha
chr16_+_51690564	0.349		CHD9	chromodomain helicase DNA binding protein 9
chr12_-_56111054	0.347		R3HDM2	R3H domain containing 2
chr2_-_242449662	0.345	NM_005018	PDCD1	programmed cell death 1
chr14_+_22410795	0.345	NM_014045	LRP10	low density lipoprotein receptor-related protein 10
chr2_-_24995402	0.344	NM_004036	ADCY3	adenylate cyclase 3
chr1_+_182040837	0.344		RGL1	ral guanine nucleotide dissociation stimulator-like 1
chr6_+_31731647	0.343	NM_019101	APOM	apolipoprotein M
chr17_+_54642152	0.341	NM_018149	C17orf71	chromosome 17 open reading frame 71
chr12_+_52132353	0.340		PCBP2	poly(rC) binding protein 2
chr17_-_44058612	0.339	NM_024017	HOXB9	homeobox B9
chr2_-_174537021	0.338	NM_001017371	SP3	Sp3 transcription factor
chr2_-_180580024	0.337	NM_020943	CWC22	CWC22 spliceosome-associated protein homolog (S. cerevisiae)
chr4_+_39376058	0.336	NM_001111112 NM_001111113 NM_005339	UBE2K	ubiquitin-conjugating enzyme E2K (UBC1 homolog, yeast)
chr14_+_38714111	0.336	NM_002687	PNN	pinin, desmosome associated protein
chr12_+_52689062	0.335	NM_022658	HOXC8	homeobox C8
chr14_+_22859236	0.334	NM_004643	PABPN1	poly(A) binding protein, nuclear 1
chr13_-_47885018	0.334		LPAR6	lysophosphatidic acid receptor 6
chr22_-_35494019	0.333	NM_001177702	IFT27	intraflagellar transport 27 homolog (Chlamydomonas)
chr6_-_31658044	0.332	NM_002341 NM_009588	LTB	lymphotoxin beta (TNF superfamily, member 3)
chr5_+_133870175	0.332
chr4_+_84596141	0.332	NM_016067	MRPS18C	mitochondrial ribosomal protein S18C
chr10_+_22580992	0.331
chr6_-_25044156	0.330		FAM65B	family with sequence similarity 65, member B
chr3_+_98966253	0.328	NM_032146 NM_177976	ARL6	ADP-ribosylation factor-like 6
chr17_+_24742068	0.326	NM_020791	TAOK1	TAO kinase 1
chr2_+_112956204	0.325	NM_153712	TTL	tubulin tyrosine ligase
chr11_-_14342627	0.325	NM_001177314	RRAS2	related RAS viral (r-ras) oncogene homolog 2
chr17_-_59403932	0.325	NM_000334	SCN4A	sodium channel, voltage-gated, type IV, alpha subunit
chr7_-_30032649	0.325	NM_017946	FKBP14	FK506 binding protein 14, 22 kDa
chr10_+_104580420	0.320
chr2_-_190892730	0.320		HIBCH	3-hydroxyisobutyryl-CoA hydrolase
chr6_-_33016561	0.320	NM_002118	HLA-DMB	major histocompatibility complex, class II, DM beta
chr10_+_129735796	0.319	NM_130435	PTPRE	protein tyrosine phosphatase, receptor type, E
chr2_-_219404755	0.319	NM_017431	PRKAG3	protein kinase, AMP-activated, gamma 3 non-catalytic subunit
chr17_-_7061641	0.319	NM_001128827	DLG4	discs, large homolog 4 (Drosophila)
chr1_+_24518501	0.317	NM_001195010	GRHL3	grainyhead-like 3 (Drosophila)
chr1_-_199348316	0.315	NM_000069	CACNA1S	calcium channel, voltage-dependent, L type, alpha 1S subunit
chr2_-_216944911	0.313	NM_020814	MARCH4	membrane-associated ring finger (C3HC4) 4
chr1_+_204797516	0.313		RASSF5	Ras association (RalGDS/AF-6) domain family member 5
chr11_+_76423082	0.312	NM_138706	B3GNT6	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 (core 3 synthase)

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.21	6.87e-14	GO:0044260	cellular macromolecule metabolic process
1.32	1.20e-11	GO:0010467	gene expression
1.17	3.79e-11	GO:0043170	macromolecule metabolic process
1.32	1.64e-10	GO:0016070	RNA metabolic process
1.28	2.19e-10	GO:0090304	nucleic acid metabolic process
1.14	1.44e-09	GO:0044237	cellular metabolic process
1.12	8.70e-08	GO:0044238	primary metabolic process
1.22	9.08e-08	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.10	3.20e-06	GO:0008152	metabolic process
1.47	1.40e-05	GO:0016071	mRNA metabolic process
1.42	2.19e-05	GO:0006396	RNA processing
1.06	4.70e-05	GO:0009987	cellular process
1.24	6.04e-05	GO:0009059	macromolecule biosynthetic process
1.52	1.11e-04	GO:0006397	mRNA processing
1.24	1.16e-04	GO:0034645	cellular macromolecule biosynthetic process
1.78	1.48e-04	GO:0051251	positive regulation of lymphocyte activation
1.19	1.65e-04	GO:0044267	cellular protein metabolic process
1.15	4.68e-04	GO:0006807	nitrogen compound metabolic process
1.82	6.16e-04	GO:0050870	positive regulation of T cell activation
1.15	6.46e-04	GO:0034641	cellular nitrogen compound metabolic process
1.73	6.56e-04	GO:0050863	regulation of T cell activation
1.64	1.19e-03	GO:0051249	regulation of lymphocyte activation
1.29	1.22e-03	GO:0032774	RNA biosynthetic process
1.14	1.28e-03	GO:0031323	regulation of cellular metabolic process
1.14	1.35e-03	GO:0080090	regulation of primary metabolic process
1.14	1.94e-03	GO:0060255	regulation of macromolecule metabolic process
1.51	3.09e-03	GO:0006412	translation
1.52	3.31e-03	GO:0008380	RNA splicing
2.16	3.35e-03	GO:0031294	lymphocyte costimulation
2.16	3.35e-03	GO:0031295	T cell costimulation
1.65	4.55e-03	GO:0050867	positive regulation of cell activation
1.65	4.57e-03	GO:0002696	positive regulation of leukocyte activation
1.53	5.28e-03	GO:0010608	posttranscriptional regulation of gene expression
1.17	6.33e-03	GO:0048519	negative regulation of biological process
1.90	6.73e-03	GO:0050851	antigen receptor-mediated signaling pathway
1.16	6.99e-03	GO:0048522	positive regulation of cellular process
1.12	7.21e-03	GO:0019222	regulation of metabolic process
1.55	9.00e-03	GO:0002694	regulation of leukocyte activation
1.34	1.16e-02	GO:0009057	macromolecule catabolic process
1.60	1.18e-02	GO:0000375	RNA splicing, via transesterification reactions
1.60	1.55e-02	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
1.60	1.55e-02	GO:0000398	nuclear mRNA splicing, via spliceosome
1.15	1.95e-02	GO:0010468	regulation of gene expression
1.07	2.41e-02	GO:0050789	regulation of biological process
1.60	2.61e-02	GO:0022411	cellular component disassembly
1.60	2.61e-02	GO:0071845	cellular component disassembly at cellular level
1.16	2.69e-02	GO:0044249	cellular biosynthetic process
1.17	2.72e-02	GO:0048523	negative regulation of cellular process
1.08	2.73e-02	GO:0050794	regulation of cellular process
1.44	3.03e-02	GO:0070647	protein modification by small protein conjugation or removal
1.51	3.04e-02	GO:0050865	regulation of cell activation
1.23	3.71e-02	GO:0031325	positive regulation of cellular metabolic process
1.62	4.77e-02	GO:0006417	regulation of translation

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.09	5.06e-20	GO:0005622	intracellular
1.09	1.33e-18	GO:0044424	intracellular part
1.12	1.09e-14	GO:0043231	intracellular membrane-bounded organelle
1.11	1.61e-14	GO:0043227	membrane-bounded organelle
1.10	1.07e-13	GO:0043229	intracellular organelle
1.10	1.94e-13	GO:0043226	organelle
1.16	7.01e-13	GO:0005634	nucleus
1.28	7.14e-12	GO:0044428	nuclear part
1.27	8.27e-12	GO:0031974	membrane-enclosed lumen
1.15	1.44e-11	GO:0044422	organelle part
1.30	3.29e-11	GO:0031981	nuclear lumen
1.27	4.11e-11	GO:0043233	organelle lumen
1.15	4.74e-11	GO:0044446	intracellular organelle part
1.27	9.37e-11	GO:0070013	intracellular organelle lumen
1.10	9.83e-10	GO:0005737	cytoplasm
1.32	2.52e-08	GO:0005654	nucleoplasm
1.17	2.96e-07	GO:0032991	macromolecular complex
1.11	1.04e-06	GO:0044444	cytoplasmic part
1.45	5.58e-06	GO:0030529	ribonucleoprotein complex
1.03	4.18e-05	GO:0044464	cell part
1.03	4.47e-05	GO:0005623	cell
1.17	5.62e-05	GO:0043228	non-membrane-bounded organelle
1.17	5.62e-05	GO:0043232	intracellular non-membrane-bounded organelle
1.19	1.17e-04	GO:0005829	cytosol
1.81	5.27e-04	GO:0016607	nuclear speck
1.39	5.68e-04	GO:0005730	nucleolus
1.56	1.90e-03	GO:0016604	nuclear body
1.13	9.17e-03	GO:0043234	protein complex
1.27	1.54e-02	GO:0044451	nucleoplasm part
3.54	2.37e-02	GO:0035631	CD40 receptor complex

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.14	1.50e-15	GO:0005515	protein binding
1.06	1.38e-08	GO:0005488	binding
1.40	6.73e-08	GO:0003723	RNA binding
1.18	3.13e-07	GO:0003676	nucleic acid binding
1.94	1.16e-02	GO:0047485	protein N-terminus binding

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