Motif ID: SRY.p2

Z-value: 1.845


Transcription factors associated with SRY.p2:

Gene SymbolEntrez IDGene Name
SRY 6736 sex determining region Y



Activity profile for motif SRY.p2.

activity profile for motif SRY.p2


Sorted Z-values histogram for motif SRY.p2

Sorted Z-values for motif SRY.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SRY.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_+_113280727 1.734 NM_006028
HTR3B
5-hydroxytryptamine (serotonin) receptor 3B
chr7_+_128136347 1.590 FAM71F1
family with sequence similarity 71, member F1
chr6_+_155579788 1.580 NM_001010927
TIAM2
T-cell lymphoma invasion and metastasis 2
chr2_+_135312655 1.555 NM_138326
ACMSD
aminocarboxymuconate semialdehyde decarboxylase
chr10_-_62002672 1.544 ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr7_+_116238309 1.494 CAPZA2
capping protein (actin filament) muscle Z-line, alpha 2
chr12_+_54132264 1.471 NM_054105
OR6C2
olfactory receptor, family 6, subfamily C, member 2
chr21_+_42492867 1.468 NM_207627
NM_207628
ABCG1

ATP-binding cassette, sub-family G (WHITE), member 1

chr3_-_150533948 1.455 NM_001184723
NM_138786
TM4SF18

transmembrane 4 L six family member 18

chr4_+_14950657 1.396 NM_001135170
C1QTNF7
C1q and tumor necrosis factor related protein 7
chr2_+_158666627 1.384 NM_173355
UPP2
uridine phosphorylase 2
chr7_-_93027057 1.378 NM_001164738
CALCR
calcitonin receptor
chr9_-_103237851 1.341 NM_000035
ALDOB
aldolase B, fructose-bisphosphate
chr8_-_18710575 1.317 NM_206909
PSD3
pleckstrin and Sec7 domain containing 3
chr3_+_39484073 1.297 NM_182935
MOBP
myelin-associated oligodendrocyte basic protein
chr1_-_115039614 1.278 NM_000036
NM_001172626
AMPD1

adenosine monophosphate deaminase 1

chr12_-_9987277 1.274 LOC100506159
hypothetical LOC100506159
chr7_+_116182676 1.208


chr7_+_38984133 1.186 NM_001166018
NM_007252
POU6F2

POU class 6 homeobox 2

chr8_-_81155564 1.144 NM_001025252
TPD52
tumor protein D52
chr8_-_110724594 1.089 NM_001099756
SYBU
syntabulin (syntaxin-interacting)
chr11_-_16380967 1.082 NM_001145819
NM_017508
SOX6

SRY (sex determining region Y)-box 6

chr6_+_168161401 1.070 NM_005355
NM_030615
KIF25

kinesin family member 25

chr3_-_150993299 1.058 NM_001144960
C3orf16
chromosome 3 open reading frame 16
chr3_+_12367993 1.057 NM_015869
PPARG
peroxisome proliferator-activated receptor gamma
chr17_-_36570508 1.053 NM_032524
KRTAP4-4
keratin associated protein 4-4
chr11_-_8921155 1.052 NM_020646
ASCL3
achaete-scute complex homolog 3 (Drosophila)
chr3_+_179736917 1.040 NM_181361
KCNMB2
potassium large conductance calcium-activated channel, subfamily M, beta member 2
chr8_+_12847521 1.013 NM_020844
KIAA1456
KIAA1456
chr1_+_66230977 0.994 NM_001037340
PDE4B
phosphodiesterase 4B, cAMP-specific
chr1_-_204455269 0.993 NM_001007544
C1orf186
chromosome 1 open reading frame 186
chr1_+_50344550 0.985 NM_001144775
ELAVL4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr17_-_36294962 0.984 NM_019010
KRT20
keratin 20
chr7_+_128802719 0.976 NM_001130722
AHCYL2
adenosylhomocysteinase-like 2
chr13_-_32678142 0.973 NM_052851
STARD13
StAR-related lipid transfer (START) domain containing 13
chr21_-_38792173 0.960 NM_001136155
NM_182918
ERG

v-ets erythroblastosis virus E26 oncogene homolog (avian)

chr1_+_116455898 0.956 NM_152367
MAB21L3
mab-21-like 3 (C. elegans)
chr11_-_18214891 0.956 NM_006512
SAA4
serum amyloid A4, constitutive
chr4_+_187227302 0.931 NM_003265
TLR3
toll-like receptor 3
chr4_+_37638450 0.926 NM_006607
PTTG2
pituitary tumor-transforming 2
chr12_+_26096757 0.924 NM_001164746
RASSF8
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chr7_+_134114912 0.918 CALD1
caldesmon 1
chr9_+_674193 0.918


chr5_-_121842680 0.910


chr6_-_117256890 0.910 NM_148963
GPRC6A
G protein-coupled receptor, family C, group 6, member A
chr3_-_47909001 0.907 MAP4
microtubule-associated protein 4
chr11_+_117762432 0.896 UBE4A
ubiquitination factor E4A (UFD2 homolog, yeast)
chr3_-_194579207 0.889 NM_198505
ATP13A5
ATPase type 13A5
chr10_-_105835525 0.881 COL17A1
collagen, type XVII, alpha 1
chr4_-_56153135 0.868 NM_152401
PDCL2
phosducin-like 2
chr5_+_36642213 0.867 NM_001166696
NM_004172
SLC1A3

solute carrier family 1 (glial high affinity glutamate transporter), member 3

chr3_+_131761867 0.866 NM_001102608
COL6A6
collagen, type VI, alpha 6
chr11_+_129484540 0.865 APLP2
amyloid beta (A4) precursor-like protein 2
chr7_+_93373755 0.863 NM_021955
GNGT1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr19_-_14800275 0.861 NM_017506
OR7A5
olfactory receptor, family 7, subfamily A, member 5
chr12_+_91620749 0.857 NM_001037671
NM_001178097
C12orf74

chromosome 12 open reading frame 74

chr10_-_105835609 0.845 NM_000494
COL17A1
collagen, type XVII, alpha 1
chr2_+_38031099 0.839 NM_001170793
NM_144713
FAM82A1

family with sequence similarity 82, member A1

chr11_-_7684516 0.838 NM_198185
OVCH2
ovochymase 2 (gene/pseudogene)
chr2_-_99238001 0.832 NM_175735
LYG2
lysozyme G-like 2
chr1_+_66570363 0.824 NM_001037339
PDE4B
phosphodiesterase 4B, cAMP-specific
chr7_+_134114957 0.805 CALD1
caldesmon 1
chr8_+_12914143 0.796 NM_001099677
KIAA1456
KIAA1456
chr11_+_5925152 0.790 NM_001003443
OR56A3
olfactory receptor, family 56, subfamily A, member 3
chr6_-_33028790 0.787 NM_006120
HLA-DMA
major histocompatibility complex, class II, DM alpha
chr11_-_13474101 0.786 NM_000315
PTH
parathyroid hormone
chr17_-_36577949 0.778 NM_033187
KRTAP4-3
keratin associated protein 4-3
chr3_+_173954940 0.773 NM_018098
ECT2
epithelial cell transforming sequence 2 oncogene
chr3_+_115099007 0.770 NM_001172105
GRAMD1C
GRAM domain containing 1C
chr5_-_66528330 0.767 NM_005582
CD180
CD180 molecule
chr1_-_177106702 0.766 NM_004673
ANGPTL1
angiopoietin-like 1
chr21_+_38550739 0.765 NM_170736
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr12_-_103846186 0.761 NM_032148
SLC41A2
solute carrier family 41, member 2
chr7_-_83108682 0.752 NM_001178129
SEMA3E
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr11_+_57547928 0.752 NM_001005212
OR9Q1
olfactory receptor, family 9, subfamily Q, member 1
chr3_+_190990142 0.746 NM_001114980
NM_001114981
NM_001114982
TP63


tumor protein p63


chr4_-_72868598 0.734 NM_000583
GC
group-specific component (vitamin D binding protein)
chr1_-_7923464 0.731 NM_001561
TNFRSF9
tumor necrosis factor receptor superfamily, member 9
chr11_-_58368555 0.729 NM_145016
GLYATL2
glycine-N-acyltransferase-like 2
chr1_+_556968 0.722


chr9_+_129066576 0.721 NM_032293
GARNL3
GTPase activating Rap/RanGAP domain-like 3
chr2_-_74424041 0.713 NM_133478
SLC4A5
solute carrier family 4, sodium bicarbonate cotransporter, member 5
chr7_-_107558021 0.708 NM_007356
LAMB4
laminin, beta 4
chr4_+_77575276 0.699 NM_020859
SHROOM3
shroom family member 3
chr2_+_166034402 0.698 NM_001172173
CSRNP3
cysteine-serine-rich nuclear protein 3
chr1_+_183970093 0.697 NM_031935
HMCN1
hemicentin 1
chr11_-_56166490 0.693 NM_001002925
OR5AP2
olfactory receptor, family 5, subfamily AP, member 2
chr1_+_36520751 0.693 THRAP3
thyroid hormone receptor associated protein 3
chr1_-_23393808 0.689 NM_000864
HTR1D
5-hydroxytryptamine (serotonin) receptor 1D
chr19_+_60962318 0.688 NM_001145014
RFPL4A
ret finger protein-like 4A
chr15_+_37330176 0.684 NM_207445
C15orf54
chromosome 15 open reading frame 54
chr6_+_10663934 0.681 NM_001491
GCNT2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr3_+_143824955 0.679 NM_002670
PLS1
plastin 1
chr8_-_7718769 0.679 NM_152250
NM_001040703
DEFB105A
DEFB105B
defensin, beta 105A
defensin, beta 105B
chr6_-_29752909 0.668 NM_001109809
ZFP57
zinc finger protein 57 homolog (mouse)
chr6_-_116973465 0.668 NM_001139444
BET3L
BET3 like (S. cerevisiae)
chr6_-_159386007 0.650 NM_054114
NM_138810
NM_152133
TAGAP


T-cell activation RhoGTPase activating protein


chr10_-_28631850 0.649 MPP7
membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
chr4_+_15038726 0.648 NM_031911
C1QTNF7
C1q and tumor necrosis factor related protein 7
chr3_+_23904086 0.647 UBE2E1
ubiquitin-conjugating enzyme E2E 1 (UBC4/5 homolog, yeast)
chr2_+_64540843 0.647 HSPC159
galectin-related protein
chr13_+_23742846 0.637 SPATA13
spermatogenesis associated 13
chr7_+_28692122 0.635 NM_001011666
CREB5
cAMP responsive element binding protein 5
chr10_-_5436781 0.634 NM_001171864
NM_024803
TUBAL3

tubulin, alpha-like 3

chr17_-_52248248 0.633 NM_001085430
C17orf67
chromosome 17 open reading frame 67
chr11_+_20005704 0.630 NAV2
neuron navigator 2
chr12_-_101396459 0.629 NM_001111284
IGF1
insulin-like growth factor 1 (somatomedin C)
chr21_+_34112456 0.622 ITSN1
intersectin 1 (SH3 domain protein)
chr8_-_125785611 0.620 MTSS1
metastasis suppressor 1
chr6_-_76259976 0.619 NM_015687
FILIP1
filamin A interacting protein 1
chr6_+_29902734 0.618 NM_002127
HLA-G
major histocompatibility complex, class I, G
chr7_+_129693938 0.617 NM_001869
CPA2
carboxypeptidase A2 (pancreatic)
chr3_-_152403636 0.617 NM_013308
GPR171
G protein-coupled receptor 171
chr3_-_11598829 0.614 NM_001128220
VGLL4
vestigial like 4 (Drosophila)
chr3_-_99236520 0.612 NM_001105580
GABRR3
gamma-aminobutyric acid (GABA) receptor, rho 3
chr6_+_12398514 0.611 NM_001168319
NM_001955
EDN1

endothelin 1

chr11_-_14342627 0.607 NM_001177314
RRAS2
related RAS viral (r-ras) oncogene homolog 2
chr6_+_31059463 0.595 NM_001010909
MUC21
mucin 21, cell surface associated
chr12_+_32546243 0.593 NM_139241
FGD4
FYVE, RhoGEF and PH domain containing 4
chr11_+_124294355 0.586 NM_001037558
HEPN1
hepatocellular carcinoma, down-regulated 1
chr6_-_139654807 0.583 NM_153235
TXLNB
taxilin beta
chr1_+_205344200 0.582 NM_000715
C4BPA
complement component 4 binding protein, alpha
chr7_-_91632525 0.576 NM_001161528
LOC401387
leucine-rich repeat and death domain-containing protein
chr8_+_21833162 0.573 XPO7
exportin 7
chr7_+_143263191 0.571 NM_001004685
OR2F2
olfactory receptor, family 2, subfamily F, member 2
chr2_-_207738858 0.569 NM_003709
KLF7
Kruppel-like factor 7 (ubiquitous)
chr7_+_28305464 0.568 NM_182899
CREB5
cAMP responsive element binding protein 5
chr10_-_50269912 0.566 NM_001080520
DRGX
dorsal root ganglia homeobox
chr3_-_152529999 0.564 NM_176894
P2RY13
purinergic receptor P2Y, G-protein coupled, 13
chr7_+_143287952 0.561 NM_012369
OR2F1
olfactory receptor, family 2, subfamily F, member 1
chr2_-_36929520 0.560 STRN
striatin, calmodulin binding protein
chr3_-_130373241 0.558 CNBP
CCHC-type zinc finger, nucleic acid binding protein
chr7_+_142590633 0.554 NM_176881
TAS2R39
taste receptor, type 2, member 39
chr6_-_52217185 0.554 NM_052872
IL17F
interleukin 17F
chr4_+_110968594 0.554 NM_006583
RRH
retinal pigment epithelium-derived rhodopsin homolog
chr1_-_116184846 0.553 NM_001111061
NHLH2
nescient helix loop helix 2
chr2_+_38009405 0.552 NM_001170792
FAM82A1
family with sequence similarity 82, member A1
chr5_+_73145098 0.552 RGNEF
190 kDa guanine nucleotide exchange factor
chr3_-_129023850 0.552 NM_007283
MGLL
monoglyceride lipase
chr6_-_2696152 0.548 NM_001012418
MYLK4
myosin light chain kinase family, member 4
chr4_-_40327396 0.547 RBM47
RNA binding motif protein 47
chr7_+_113853790 0.547 NM_001172767
NM_148899
FOXP2

forkhead box P2

chr18_+_18969724 0.547 NM_001100619
CABLES1
Cdk5 and Abl enzyme substrate 1
chr4_-_68432293 0.545 NM_004262
TMPRSS11D
transmembrane protease, serine 11D
chr1_+_33494745 0.545 NM_152493
ZNF362
zinc finger protein 362
chr3_+_152970904 0.544 LOC201651
arylacetamide deacetylase (esterase) pseudogene
chr3_+_137224266 0.543 NM_181897
PPP2R3A
protein phosphatase 2, regulatory subunit B'', alpha
chr11_+_5714253 0.543 NM_001005180
OR56B1
olfactory receptor, family 56, subfamily B, member 1
chr1_-_108032645 0.542 NM_001079874
VAV3
vav 3 guanine nucleotide exchange factor
chr15_-_32398220 0.538 NM_005135
SLC12A6
solute carrier family 12 (potassium/chloride transporters), member 6
chr10_+_70650064 0.537 NM_025130
HKDC1
hexokinase domain containing 1
chr13_-_33148899 0.537 STARD13
StAR-related lipid transfer (START) domain containing 13
chr18_+_7936885 0.537 PTPRM
protein tyrosine phosphatase, receptor type, M
chr12_+_70618892 0.535 NM_173353
TPH2
tryptophan hydroxylase 2
chr10_-_7699192 0.533 ITIH5
inter-alpha (globulin) inhibitor H5
chr2_-_113310796 0.531 NM_000576
IL1B
interleukin 1, beta
chr4_+_47403107 0.530


chr11_+_36274300 0.530 NM_001160167
PRR5L
proline rich 5 like
chr5_+_121493113 0.526 NM_207317
ZNF474
zinc finger protein 474
chr6_+_10693964 0.525 NM_145655
GCNT2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr10_-_91092410 0.522 LIPA
lipase A, lysosomal acid, cholesterol esterase
chr1_-_7998265 0.519 ERRFI1
ERBB receptor feedback inhibitor 1
chr6_-_25679197 0.519


chr15_-_68781662 0.517 NM_001008224
UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr3_-_194118627 0.517 NM_178496
MB21D2
Mab-21 domain containing 2
chr2_-_21084077 0.513 APOB
apolipoprotein B (including Ag(x) antigen)
chr6_+_73133152 0.513 NM_001168411
RIMS1
regulating synaptic membrane exocytosis 1
chr1_+_92190296 0.512 NM_001726
BRDT
bromodomain, testis-specific
chr11_-_117600918 0.512 NM_001098526
AMICA1
adhesion molecule, interacts with CXADR antigen 1
chr11_-_85108030 0.510 NM_001162952
NM_206930
SYTL2

synaptotagmin-like 2

chrX_-_15593074 0.507 NM_020665
TMEM27
transmembrane protein 27
chr15_+_60146467 0.507 NM_207322
C2CD4A
C2 calcium-dependent domain containing 4A
chr5_+_137231443 0.505 NM_001135940
NM_006790
MYOT

myotilin

chr11_-_4675524 0.503 NM_030774
OR51E2
olfactory receptor, family 51, subfamily E, member 2
chr3_+_173043832 0.497 NM_001164436
TMEM212
transmembrane protein 212
chr4_-_186814852 0.497 SORBS2
sorbin and SH3 domain containing 2
chr14_-_88953059 0.494 NM_005197
FOXN3
forkhead box N3
chr1_-_150353179 0.492 NM_007113
TCHH
trichohyalin
chr3_+_153014550 0.490 NM_001086
AADAC
arylacetamide deacetylase (esterase)
chr6_-_24985432 0.490 NM_015864
FAM65B
family with sequence similarity 65, member B
chr17_-_36594652 0.489 NM_033060
KRTAP4-1
keratin associated protein 4-1
chr21_+_38566298 0.487 NM_170737
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr15_+_83467295 0.485 PDE8A
phosphodiesterase 8A
chr4_+_39874921 0.485 NM_004310
RHOH
ras homolog gene family, member H
chr1_+_40635058 0.484 NM_001198980
SMAP2
small ArfGAP2
chr1_-_20318578 0.480 NM_012400
PLA2G2D
phospholipase A2, group IID
chr10_-_30958631 0.480 NM_183058
LYZL2
lysozyme-like 2
chr12_-_10142779 0.478 NM_016511
CLEC1A
C-type lectin domain family 1, member A
chr9_-_14912419 0.478


chr1_+_557269 0.478


chr1_+_242281199 0.477 ZNF238
zinc finger protein 238
chr1_+_196153122 0.476 NM_020204
LHX9
LIM homeobox 9
chr3_+_100840129 0.474 NM_001850
NM_020351
COL8A1

collagen, type VIII, alpha 1

chr9_+_90193807 0.474 SPIN1
spindlin 1
chr1_-_203657803 0.473 NM_001001552
NM_001199050
NM_001199051
NM_001199052
LEMD1



LEM domain containing 1



chr4_+_35962038 0.473 NM_001170700
DTHD1
death domain containing 1
chr7_-_30032649 0.473 NM_017946
FKBP14
FK506 binding protein 14, 22 kDa
chr3_+_115040369 0.472 NM_017577
GRAMD1C
GRAM domain containing 1C
chr5_+_140537554 0.471 NM_019120
PCDHB8
protocadherin beta 8
chr11_+_123945102 0.471 NM_001005194
OR8A1
olfactory receptor, family 8, subfamily A, member 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.39 1.69e-02 GO:0007600 sensory perception
1.51 3.82e-02 GO:0007606 sensory perception of chemical stimulus

Nothing significant found in compartment category.

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.54 1.51e-02 GO:0004984 olfactory receptor activity