Motif ID: TBP.p2

Z-value: 1.782


Transcription factors associated with TBP.p2:

Gene SymbolEntrez IDGene Name
TBP 6908 TATA box binding protein

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TBPchr6_+_170705345-0.194.8e-01Click!


Activity profile for motif TBP.p2.

activity profile for motif TBP.p2


Sorted Z-values histogram for motif TBP.p2

Sorted Z-values for motif TBP.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TBP.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_-_24869945 2.486 NM_006158
NEFL
neurofilament, light polypeptide
chr15_+_60146467 2.361 NM_207322
C2CD4A
C2 calcium-dependent domain containing 4A
chr4_-_108176901 1.974 NM_014421
DKK2
dickkopf homolog 2 (Xenopus laevis)
chr7_+_115650240 1.716 NM_152829
TES
testis derived transcript (3 LIM domains)
chr11_-_102156531 1.707 NM_002425
MMP10
matrix metallopeptidase 10 (stromelysin 2)
chr19_-_12773591 1.577 NM_005809
NM_181738
PRDX2

peroxiredoxin 2

chr12_-_14929991 1.490 NM_000900
NM_001190839
MGP

matrix Gla protein

chr1_+_150925222 1.425 NM_014357
LCE2B
late cornified envelope 2B
chr1_-_151296611 1.399 NM_005988
SPRR2A
small proline-rich protein 2A
chr20_-_38751289 1.393 NM_005461
MAFB
v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)
chr13_-_52320774 1.331 NM_002590
NM_032949
PCDH8

protocadherin 8

chr22_+_28206180 1.330 NM_021076
NEFH
neurofilament, heavy polypeptide
chr21_+_44844924 1.286 NM_198689
KRTAP10-7
keratin associated protein 10-7
chr15_-_60244773 1.279 NM_001007595
C2CD4B
C2 calcium-dependent domain containing 4B
chr1_+_159495140 1.270 NM_001102566
PCP4L1
Purkinje cell protein 4 like 1
chr7_+_24290331 1.262 NM_000905
NPY
neuropeptide Y
chr4_+_74953971 1.220 NM_001511
CXCL1
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chr8_-_23077392 1.209 NM_003840
TNFRSF10D
tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
chr7_-_526005 1.207 NM_002607
NM_033023
PDGFA

platelet-derived growth factor alpha polypeptide

chr9_+_136912474 1.192 NM_004108
NM_015837
FCN2

ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin)

chr1_-_26266571 1.174 NM_032588
TRIM63
tripartite motif containing 63
chr11_-_2907169 1.166 NM_003311
PHLDA2
pleckstrin homology-like domain, family A, member 2
chr8_+_23016271 1.159 NM_003841
TNFRSF10C
tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
chr8_+_23157094 1.089 NM_152272
CHMP7
CHMP family, member 7
chr21_+_44818033 1.086 NM_198687
KRTAP10-4
keratin associated protein 10-4
chr11_-_2863536 1.082 NM_000076
NM_001122630
NM_001122631
CDKN1C


cyclin-dependent kinase inhibitor 1C (p57, Kip2)


chr1_-_20178680 1.028 NM_001161729
PLA2G2A
phospholipase A2, group IIA (platelets, synovial fluid)
chr17_+_29606408 1.026 NM_002982
CCL2
chemokine (C-C motif) ligand 2
chr19_-_54618410 1.015 NM_178449
PTH2
parathyroid hormone 2
chr21_-_44911250 1.014 NM_181684
KRTAP12-2
keratin associated protein 12-2
chr4_-_175680157 0.999 HPGD
hydroxyprostaglandin dehydrogenase 15-(NAD)
chr11_+_65945050 0.997 NM_178864
NPAS4
neuronal PAS domain protein 4
chr3_-_152529999 0.993 NM_176894
P2RY13
purinergic receptor P2Y, G-protein coupled, 13
chr11_-_102001259 0.991 NM_004771
MMP20
matrix metallopeptidase 20
chr17_-_36834183 0.990 NM_003770
KRT37
keratin 37
chr10_-_62373828 0.975 NM_014836
RHOBTB1
Rho-related BTB domain containing 1
chr9_+_91409746 0.975 NM_006705
GADD45G
growth arrest and DNA-damage-inducible, gamma
chr22_+_29810981 0.959 SMTN
smoothelin
chr21_-_44795769 0.955 NM_198693
KRTAP10-2
keratin associated protein 10-2
chr20_+_3000265 0.948 NM_000915
OXT
oxytocin, prepropeptide
chr17_+_77910411 0.946 NM_207459
TEX19
testis expressed 19
chr19_+_10242763 0.907 ICAM1
intercellular adhesion molecule 1
chr17_-_45901173 0.899 NM_001267
CHAD
chondroadherin
chr1_+_151270301 0.884 NM_003125
SPRR1B
small proline-rich protein 1B
chr11_-_5232480 0.874 NM_000184
HBG1
HBG2
hemoglobin, gamma A
hemoglobin, gamma G
chr12_+_50686990 0.866 NM_181711
GRASP
GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein
chr10_+_53744043 0.853 NM_012242
DKK1
dickkopf homolog 1 (Xenopus laevis)
chr11_+_43920385 0.824 NM_001145033
C11orf96
chromosome 11 open reading frame 96
chr1_+_17507276 0.821 NM_012387
PADI4
peptidyl arginine deiminase, type IV
chr11_-_102250876 0.818 NM_002426
MMP12
matrix metallopeptidase 12 (macrophage elastase)
chr11_+_60746396 0.816 NM_001079808
PGA5
PGA3
PGA4
pepsinogen 5, group I (pepsinogen A)
pepsinogen 3, group I (pepsinogen A)
pepsinogen 4, group I (pepsinogen A)
chr12_-_51153788 0.812 NM_173086
KRT6C
keratin 6C
chr6_+_127940011 0.809 NM_001010905
C6orf58
chromosome 6 open reading frame 58
chr8_+_24827173 0.808 NM_005382
NEFM
neurofilament, medium polypeptide
chr17_-_59312892 0.806 NM_002059
NM_022556
NM_022557
NM_022558
GH2



growth hormone 2



chrX_-_103386215 0.806 NM_153448
ESX1
ESX homeobox 1
chr19_-_44386731 0.794 NM_001080468
SYCN
syncollin
chr17_-_36192311 0.794 NM_181537
KRT27
keratin 27
chr11_-_76059435 0.787 NM_001128922
LRRC32
leucine rich repeat containing 32
chr21_+_44881700 0.781 NM_181688
KRTAP10-10
keratin associated protein 10-10
chr1_+_150749943 0.780 NM_178438
LCE5A
late cornified envelope 5A
chr1_-_151630168 0.777 NM_002964
S100A8
S100 calcium binding protein A8
chrX_-_139414890 0.775 NM_005634
SOX3
SRY (sex determining region Y)-box 3
chr1_+_157824239 0.773 NM_001639
APCS
amyloid P component, serum
chr22_+_22445035 0.769 NM_005940
MMP11
matrix metallopeptidase 11 (stromelysin 3)
chr15_-_61461127 0.764 NM_001218
NM_206925
CA12

carbonic anhydrase XII

chr19_+_19183763 0.755 NM_004386
NCAN
neurocan
chr1_-_117554999 0.752 NM_024626
VTCN1
V-set domain containing T cell activation inhibitor 1
chr16_-_55259405 0.749 NM_005950
MT1G
metallothionein 1G
chr11_-_6418705 0.749 NM_000613
HPX
hemopexin
chr5_-_153837975 0.749 HAND1
heart and neural crest derivatives expressed 1
chr8_+_24827181 0.747 NEFM
neurofilament, medium polypeptide
chr6_-_134540666 0.745 NM_001143677
SGK1
serum/glucocorticoid regulated kinase 1
chr14_+_74815233 0.743 NM_005252
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr3_+_110338250 0.732 FLJ22763
hypothetical LOC401081
chr16_+_55249355 0.729 NM_005949
MT1F
metallothionein 1F
chr19_-_40673185 0.719 NM_207392
KRTDAP
keratinocyte differentiation-associated protein
chr11_+_60765219 0.718 NM_014224
PGA5
pepsinogen 5, group I (pepsinogen A)
chr12_-_51298599 0.718 NM_175068
KRT73
keratin 73
chr12_-_87498225 0.714 NM_000899
NM_003994
KITLG

KIT ligand

chr5_+_176744037 0.708 NM_001167579
NM_003052
SLC34A1

solute carrier family 34 (sodium phosphate), member 1

chr4_-_75183700 0.707 CXCL2
chemokine (C-X-C motif) ligand 2
chr17_+_36642240 0.706 NM_031962
KRTAP9-9
KRTAP9-3
keratin associated protein 9-9
keratin associated protein 9-3
chr10_+_94823636 0.704 NM_000783
CYP26A1
cytochrome P450, family 26, subfamily A, polypeptide 1
chr6_-_2848460 0.695 NM_004155
SERPINB9
serpin peptidase inhibitor, clade B (ovalbumin), member 9
chr6_-_137857213 0.693 NM_175747
OLIG3
oligodendrocyte transcription factor 3
chr8_-_27528105 0.689 CLU
clusterin
chr8_-_6722848 0.686 NM_005218
DEFB1
defensin, beta 1
chr15_-_72804763 0.681 NM_000499
CYP1A1
cytochrome P450, family 1, subfamily A, polypeptide 1
chr12_-_51065629 0.663 NM_033045
KRT84
keratin 84
chr1_+_6226838 0.661 NM_001024598
HES3
hairy and enhancer of split 3 (Drosophila)
chr21_+_44871467 0.654 NM_198690
KRTAP10-9
keratin associated protein 10-9
chr21_-_27139143 0.648 ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr1_+_150997129 0.641 NM_001025231
KPRP
keratinocyte proline-rich protein
chr19_-_51109875 0.634 NM_001029861
NANOS2
nanos homolog 2 (Drosophila)
chr17_-_37144408 0.632 NM_001079870
NM_001079871
NM_177977
HAP1


huntingtin-associated protein 1


chr1_+_150914394 0.630 NM_178429
LCE2C
late cornified envelope 2C
chr9_-_103237851 0.618 NM_000035
ALDOB
aldolase B, fructose-bisphosphate
chr9_-_135074364 0.614 NM_014581
OBP2B
OBP2A
odorant binding protein 2B
odorant binding protein 2A
chr14_-_52487558 0.612 NM_001134999
NM_001135000
NM_006832
FERMT2


fermitin family member 2


chr1_+_151596953 0.601 NM_002965
S100A9
S100 calcium binding protein A9
chr1_-_151310707 0.599 NM_001017418
SPRR2B
small proline-rich protein 2B
chr11_-_102331643 0.595 NM_002427
MMP13
matrix metallopeptidase 13 (collagenase 3)
chr16_+_25135783 0.593 NM_001169
AQP8
aquaporin 8
chr1_-_148051859 0.592 NM_001123375
HIST2H3D
histone cluster 2, H3d
chr14_-_54438913 0.587 NM_000161
NM_001024024
NM_001024070
NM_001024071
GCH1



GTP cyclohydrolase 1



chr4_-_157006827 0.584 NM_017419
ACCN5
amiloride-sensitive cation channel 5, intestinal
chr18_+_55038369 0.580 NM_001012512
NM_001012513
NM_002091
GRP


gastrin-releasing peptide


chr6_-_30188845 0.578 NM_007028
TRIM31
tripartite motif containing 31
chr15_-_61460967 0.577 CA12
carbonic anhydrase XII
chr4_-_46086218 0.576 GABRA2
gamma-aminobutyric acid (GABA) A receptor, alpha 2
chr17_-_36276987 0.570 NM_000223
KRT12
keratin 12
chr1_-_151280201 0.568 NM_006945
SPRR2D
small proline-rich protein 2D
chr1_+_150902495 0.567 NM_178430
LCE2D
late cornified envelope 2D
chr9_+_116125123 0.560 NM_000607
ORM1
orosomucoid 1
chr11_+_1607580 0.555 NM_001001480
KRTAP5-5
keratin associated protein 5-5
chr2_-_162717159 0.555 NM_002054
GCG
glucagon
chr19_-_46048033 0.552 NM_000762
CYP2A6
cytochrome P450, family 2, subfamily A, polypeptide 6
chr8_-_27528215 0.551 NM_001831
CLU
clusterin
chrX_+_16578201 0.543 NM_004057
S100G
S100 calcium binding protein G
chr1_-_154941861 0.542 NM_001878
CRABP2
cellular retinoic acid binding protein 2
chr4_-_46086150 0.541 NM_001114175
GABRA2
gamma-aminobutyric acid (GABA) A receptor, alpha 2
chr17_+_53625084 0.535 NM_000502
EPX
eosinophil peroxidase
chr19_+_40465249 0.532 NM_021175
HAMP
hepcidin antimicrobial peptide
chr5_-_57791544 0.530 NM_006622
PLK2
polo-like kinase 2
chrX_-_30237403 0.530 NM_000475
NR0B1
nuclear receptor subfamily 0, group B, member 1
chr4_-_140317686 0.530 ELF2
E74-like factor 2 (ets domain transcription factor)
chr16_+_57091546 0.527 NDRG4
NDRG family member 4
chr17_-_36938025 0.520 KRT19
keratin 19
chr15_+_72828235 0.519 NM_000761
CYP1A2
cytochrome P450, family 1, subfamily A, polypeptide 2
chr19_+_38485583 0.519 LOC80054
hypothetical LOC80054
chr1_-_202432165 0.519 NM_002256
KISS1
KiSS-1 metastasis-suppressor
chr10_-_100017933 0.516 NM_032211
LOXL4
lysyl oxidase-like 4
chr12_-_51001407 0.513 NM_002282
KRT83
keratin 83
chr17_-_36113502 0.505 NM_019016
KRT24
keratin 24
chr11_-_102219450 0.505 NM_002422
MMP3
matrix metallopeptidase 3 (stromelysin 1, progelatinase)
chr17_-_59349867 0.498 NM_000515
NM_022559
NM_022560
NM_022561
NM_022562
GH1




growth hormone 1




chr1_+_85819004 0.497 NM_001554
CYR61
cysteine-rich, angiogenic inducer, 61
chr12_-_51281482 0.497 NM_001146225
NM_001146226
NM_080747
KRT72


keratin 72


chr12_-_91063441 0.496 NM_001731
BTG1
B-cell translocation gene 1, anti-proliferative
chr19_+_791963 0.493 PRTN3
proteinase 3
chr9_+_21399132 0.491 NM_002170
IFNA8
interferon, alpha 8
chr15_+_39008822 0.490 NM_019074
DLL4
delta-like 4 (Drosophila)
chr21_-_44784499 0.489 NM_198691
KRTAP10-1
keratin associated protein 10-1
chr9_+_33785558 0.487 NM_002771
PRSS3
protease, serine, 3
chr1_-_58815415 0.485 TACSTD2
tumor-associated calcium signal transducer 2
chr17_+_36599664 0.485 NM_001190460
KRTAP9-1
keratin associated protein 9-1
chr21_-_27139563 0.484 NM_006988
ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr9_-_116732403 0.482 NM_001244
TNFSF8
tumor necrosis factor (ligand) superfamily, member 8
chr3_-_24511456 0.476 THRB
thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian)
chr20_+_2224612 0.475 NM_003245
TGM3
transglutaminase 3 (E polypeptide, protein-glutamine-gamma-glutamyltransferase)
chr17_-_59304729 0.469 NM_020991
NM_022644
NM_022645
CSH2


chorionic somatomammotropin hormone 2


chr21_-_44836811 0.469 NM_198688
KRTAP10-6
keratin associated protein 10-6
chr19_+_18357966 0.467 NM_004864
GDF15
growth differentiation factor 15
chr17_+_36647795 0.452 NM_031963
KRTAP9-8
keratin associated protein 9-8
chr17_-_36165050 0.452 NM_181534
KRT25
keratin 25
chr17_-_68100537 0.448 LOC100499467
hypothetical LOC100499467
chr8_-_134378630 0.446 NM_001135242
NM_006096
NDRG1

N-myc downstream regulated 1

chr11_+_60727559 0.446 NM_001079807
PGA3
PGA4
pepsinogen 3, group I (pepsinogen A)
pepsinogen 4, group I (pepsinogen A)
chr22_-_35545462 0.444 NM_002854
PVALB
parvalbumin
chr17_-_36928604 0.442 NM_002275
KRT15
keratin 15
chr11_+_30209138 0.439 NM_000510
NM_001018080
FSHB

follicle stimulating hormone, beta polypeptide

chr14_+_64077171 0.438 HSPA2
heat shock 70kDa protein 2
chr8_+_86538307 0.433 NM_005181
CA3
carbonic anhydrase III, muscle specific
chr2_-_27384617 0.431 NM_003353
UCN
urocortin
chr19_-_2002222 0.430 NM_017572
NM_199054
MKNK2

MAP kinase interacting serine/threonine kinase 2

chr11_+_1675000 0.430 NM_001012416
KRTAP5-6
keratin associated protein 5-6
chr5_+_71050745 0.423 NM_004291
CARTPT
CART prepropeptide
chr10_+_6284845 0.421 NM_004566
PFKFB3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr19_+_51059357 0.418 NM_004497
FOXA3
forkhead box A3
chr12_-_51332214 0.416 NM_000423
KRT2
keratin 2
chr11_-_59369501 0.416 NM_005142
GIF
gastric intrinsic factor (vitamin B synthesis)
chr20_-_43410437 0.409 NM_002999
SDC4
syndecan 4
chr12_+_129212955 0.409 NM_007197
FZD10
frizzled homolog 10 (Drosophila)
chr16_+_55156461 0.409 NM_032935
MT4
metallothionein 4
chr19_+_52504914 0.409 NM_001736
C5AR1
complement component 5a receptor 1
chr21_+_44729875 0.404


chr19_+_13124870 0.404 IER2
immediate early response 2
chr1_+_184532027 0.404 NM_001127708
NM_001127709
NM_001127710
NM_005807
PRG4



proteoglycan 4



chr16_-_11277806 0.403 NM_002762
PRM2
protamine 2
chr9_+_135491305 0.403 NM_000787
DBH
dopamine beta-hydroxylase (dopamine beta-monooxygenase)
chr1_-_147665783 0.403 HIST2H2BF
histone cluster 2, H2bf
chr11_-_93774223 0.395 NM_016540
GPR83
G protein-coupled receptor 83
chr1_+_45822246 0.393 NM_001195193
NM_002482
NM_152298
NASP


nuclear autoantigenic sperm protein (histone-binding)


chr15_+_37660568 0.392 NM_003246
THBS1
thrombospondin 1
chr16_+_155972 0.384 NM_001003938
HBM
hemoglobin, mu
chr17_+_7494964 0.383 NM_001678
ATP1B2
ATPase, Na+/K+ transporting, beta 2 polypeptide
chr1_+_148089251 0.382 NM_001040874
NM_003516
HIST2H2AA4
HIST2H2AA3
histone cluster 2, H2aa4
histone cluster 2, H2aa3
chr1_+_161305558 0.381 NM_001113381
RGS4
regulator of G-protein signaling 4
chr17_+_7495436 0.378 ATP1B2
ATPase, Na+/K+ transporting, beta 2 polypeptide
chr12_+_48630790 0.375 NM_000486
AQP2
aquaporin 2 (collecting duct)
chr15_+_43193810 0.374 NM_207581
DUOXA2
dual oxidase maturation factor 2
chr17_+_29707583 0.373 NM_005408
CCL13
chemokine (C-C motif) ligand 13
chr11_+_68208583 0.373 GAL
galanin prepropeptide
chr7_-_16471817 0.372 NM_015464
SOSTDC1
sclerostin domain containing 1
chr13_-_113155839 0.371 NM_138430
ADPRHL1
ADP-ribosylhydrolase like 1
chr20_+_36365965 0.371 NM_001725
BPI
bactericidal/permeability-increasing protein
chr21_-_44899003 0.363 NM_198698
KRTAP12-4
keratin associated protein 12-4
chr17_-_71287417 0.360 NM_005324
H3F3B
H3 histone, family 3B (H3.3B)
chr11_-_56905178 0.359 NM_006093
PRG3
proteoglycan 3

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.94 1.20e-11 GO:0042221 response to chemical stimulus
1.64 9.00e-11 GO:0032502 developmental process
2.00 2.32e-10 GO:0048513 organ development
11.34 2.60e-10 GO:0031424 keratinization
2.25 1.01e-09 GO:0010033 response to organic substance
2.61 1.62e-09 GO:0006952 defense response
1.69 1.70e-09 GO:0048856 anatomical structure development
1.47 3.30e-09 GO:0032501 multicellular organismal process
1.61 1.98e-08 GO:0007275 multicellular organismal development
1.69 2.87e-08 GO:0048731 system development
3.79 3.53e-08 GO:0006954 inflammatory response
7.24 4.67e-08 GO:0009913 epidermal cell differentiation
4.39 6.89e-08 GO:0008544 epidermis development
3.79 6.92e-08 GO:0010035 response to inorganic substance
1.75 8.74e-08 GO:0006950 response to stress
2.38 2.70e-07 GO:0009888 tissue development
7.44 3.87e-07 GO:0030216 keratinocyte differentiation
2.23 4.95e-06 GO:0009611 response to wounding
2.33 8.58e-06 GO:0006955 immune response
1.96 2.47e-05 GO:0002376 immune system process
1.67 4.11e-05 GO:0065008 regulation of biological quality
2.12 4.50e-05 GO:0070887 cellular response to chemical stimulus
2.42 5.90e-05 GO:0009725 response to hormone stimulus
1.32 6.15e-05 GO:0050896 response to stimulus
3.81 2.39e-04 GO:0010038 response to metal ion
2.26 3.40e-04 GO:0009719 response to endogenous stimulus
1.64 3.87e-04 GO:0030154 cell differentiation
2.44 6.13e-04 GO:0009607 response to biotic stimulus
2.31 6.55e-04 GO:0009887 organ morphogenesis
3.57 7.26e-04 GO:0030855 epithelial cell differentiation
1.60 1.45e-03 GO:0048869 cellular developmental process
7.09 1.64e-03 GO:0034614 cellular response to reactive oxygen species
6.06 2.48e-03 GO:0002526 acute inflammatory response
8.82 3.43e-03 GO:0044243 multicellular organismal catabolic process
1.95 3.85e-03 GO:0051704 multi-organism process
10.42 4.37e-03 GO:0045103 intermediate filament-based process
1.75 5.96e-03 GO:0051239 regulation of multicellular organismal process
1.95 5.97e-03 GO:0040011 locomotion
9.92 6.36e-03 GO:0030574 collagen catabolic process
5.46 7.42e-03 GO:0034599 cellular response to oxidative stress
16.54 8.52e-03 GO:0045109 intermediate filament organization
6.70 9.64e-03 GO:0072593 reactive oxygen species metabolic process
2.49 1.04e-02 GO:0060429 epithelium development
1.67 1.08e-02 GO:0009653 anatomical structure morphogenesis
1.88 1.27e-02 GO:0050793 regulation of developmental process
4.35 1.40e-02 GO:0000302 response to reactive oxygen species
2.02 1.48e-02 GO:0002682 regulation of immune system process
1.98 1.64e-02 GO:2000026 regulation of multicellular organismal development
14.88 1.66e-02 GO:0071285 cellular response to lithium ion
8.68 1.74e-02 GO:0042743 hydrogen peroxide metabolic process
1.34 2.03e-02 GO:0051716 cellular response to stimulus
2.35 2.22e-02 GO:0051707 response to other organism
10.51 2.26e-02 GO:0010226 response to lithium ion
10.51 2.26e-02 GO:0045104 intermediate filament cytoskeleton organization
3.82 2.88e-02 GO:0007565 female pregnancy
2.68 3.07e-02 GO:0048545 response to steroid hormone stimulus
6.62 3.59e-02 GO:0044236 multicellular organismal metabolic process
2.45 4.16e-02 GO:0051240 positive regulation of multicellular organismal process
6.44 4.44e-02 GO:0006953 acute-phase response

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
9.63 2.88e-36 GO:0005882 intermediate filament
8.33 1.39e-32 GO:0045111 intermediate filament cytoskeleton
3.36 2.82e-28 GO:0044421 extracellular region part
3.76 8.27e-28 GO:0005615 extracellular space
12.65 5.36e-27 GO:0045095 keratin filament
2.36 2.27e-23 GO:0005576 extracellular region
2.16 2.97e-12 GO:0005856 cytoskeleton
2.28 1.21e-09 GO:0044430 cytoskeletal part
1.57 3.17e-06 GO:0043228 non-membrane-bounded organelle
1.57 3.17e-06 GO:0043232 intracellular non-membrane-bounded organelle
2.81 1.20e-05 GO:0031012 extracellular matrix
11.34 4.65e-05 GO:0001533 cornified envelope
5.28 1.28e-03 GO:0000786 nucleosome
12.40 6.11e-03 GO:0005833 hemoglobin complex
2.44 7.87e-03 GO:0005578 proteinaceous extracellular matrix

Gene overrepresentation in function category:

enrichment   p-value GO term description
3.13 4.63e-13 GO:0005198 structural molecule activity
4.79 4.50e-11 GO:0005125 cytokine activity
2.36 5.04e-10 GO:0005102 receptor binding
6.32 3.41e-09 GO:0005179 hormone activity
4.51 7.04e-09 GO:0005126 cytokine receptor binding
8.41 7.37e-07 GO:0008009 chemokine activity
7.59 2.96e-06 GO:0042379 chemokine receptor binding
3.46 4.45e-04 GO:0001664 G-protein-coupled receptor binding
3.86 6.11e-04 GO:0046906 tetrapyrrole binding
6.62 6.35e-04 GO:0019825 oxygen binding
13.74 6.87e-04 GO:0005344 oxygen transporter activity
3.87 1.19e-03 GO:0020037 heme binding
23.81 2.18e-03 GO:0046870 cadmium ion binding
5.73 2.55e-03 GO:0005507 copper ion binding
2.00 5.17e-03 GO:0005509 calcium ion binding
2.86 8.03e-03 GO:0005506 iron ion binding