Motif ID: TCF4_dimer.p2

Z-value: 2.112


Transcription factors associated with TCF4_dimer.p2:

Gene SymbolEntrez IDGene Name
TCF4 6925 transcription factor 4

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TCF4chr18_-_51406841-0.116.9e-01Click!


Activity profile for motif TCF4_dimer.p2.

activity profile for motif TCF4_dimer.p2


Sorted Z-values histogram for motif TCF4_dimer.p2

Sorted Z-values for motif TCF4_dimer.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TCF4_dimer.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr22_+_20068039 3.384 NM_001128635
 RIMBP3B
RIMS binding protein 3B
chr22_-_20235372 3.371 NM_001128635
 RIMBP3B
RIMS binding protein 3B
chr11_+_70926718 3.326 NM_021046
 KRTAP5-8
keratin associated protein 5-8
chr7_-_130891861 3.016 NM_001018111
NM_005397
 PODXL

podocalyxin-like

chr2_+_85834111 2.581 NM_032827
 ATOH8
atonal homolog 8 (Drosophila)
chr17_+_36493927 2.387 NM_033061
 KRTAP4-7
keratin associated protein 4-7
chr9_-_96441409 2.322 FBP1
fructose-1,6-bisphosphatase 1
chr15_+_81567327 2.161 NM_001144903
NM_023003
 TM6SF1

transmembrane 6 superfamily member 1

chr15_-_53822468 2.103 NM_173814
 PRTG
protogenin
chr2_-_241484245 2.010 NM_001085437
 C2orf54
chromosome 2 open reading frame 54
chr13_+_30378311 1.962 NM_032849
 C13orf33
chromosome 13 open reading frame 33
chr9_-_96441654 1.810 NM_000507
 FBP1
fructose-1,6-bisphosphatase 1
chr8_+_37773991 1.769 GPR124
G protein-coupled receptor 124
chr17_-_36594652 1.751 NM_033060
 KRTAP4-1
keratin associated protein 4-1
chr17_+_4348877 1.738 NM_001124758
 SPNS2
spinster homolog 2 (Drosophila)
chr19_+_43446937 1.689 NM_001166103
NM_021102
 SPINT2

serine peptidase inhibitor, Kunitz type, 2

chrX_-_50573759 1.664 NM_020717
 SHROOM4
shroom family member 4
chr12_-_89873081 1.654 NM_152638
 C12orf12
chromosome 12 open reading frame 12
chr15_-_42274529 1.643 NM_032892
 FRMD5
FERM domain containing 5
chr14_+_76298693 1.636 VASH1
vasohibin 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
1.54 3.05e-02 GO:0003012 muscle system process
1.44 2.90e-02 GO:0061061 muscle structure development
1.33 8.65e-04 GO:0007167 enzyme linked receptor protein signaling pathway
1.33 1.82e-02 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.19 3.71e-02 GO:0009966 regulation of signal transduction
1.14 1.65e-04 GO:0007165 signal transduction
1.13 2.78e-04 GO:0023052 signaling
1.11 8.18e-03 GO:0051716 cellular response to stimulus

Gene overrepresentation in compartment category:

Showing 1 to 9 of 9 entries
enrichment   p-value GO term description
1.87 6.23e-06 GO:0044449 contractile fiber part
1.81 3.42e-04 GO:0030017 sarcomere
1.80 2.15e-05 GO:0043292 contractile fiber
1.76 1.83e-04 GO:0030016 myofibril
1.51 7.98e-03 GO:0030424 axon
1.42 3.45e-03 GO:0015629 actin cytoskeleton
1.27 1.26e-02 GO:0030054 cell junction
1.13 2.86e-02 GO:0005829 cytosol
1.06 5.21e-03 GO:0005737 cytoplasm

Gene overrepresentation in function category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
1.36 4.56e-02 GO:0003779 actin binding
1.08 1.74e-04 GO:0005515 protein binding