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Motif ID: TCF4_dimer.p2

Z-value: 2.112

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr22_+_20068039	3.384	NM_001128635	RIMBP3B	RIMS binding protein 3B
chr22_-_20235372	3.371	NM_001128635	RIMBP3B	RIMS binding protein 3B
chr11_+_70926718	3.326	NM_021046	KRTAP5-8	keratin associated protein 5-8
chr7_-_130891861	3.016	NM_001018111 NM_005397	PODXL	podocalyxin-like
chr2_+_85834111	2.581	NM_032827	ATOH8	atonal homolog 8 (Drosophila)
chr17_+_36493927	2.387	NM_033061	KRTAP4-7	keratin associated protein 4-7
chr9_-_96441409	2.322		FBP1	fructose-1,6-bisphosphatase 1
chr15_+_81567327	2.161	NM_001144903 NM_023003	TM6SF1	transmembrane 6 superfamily member 1
chr15_-_53822468	2.103	NM_173814	PRTG	protogenin
chr2_-_241484245	2.010	NM_001085437	C2orf54	chromosome 2 open reading frame 54
chr13_+_30378311	1.962	NM_032849	C13orf33	chromosome 13 open reading frame 33
chr9_-_96441654	1.810	NM_000507	FBP1	fructose-1,6-bisphosphatase 1
chr8_+_37773991	1.769		GPR124	G protein-coupled receptor 124
chr17_-_36594652	1.751	NM_033060	KRTAP4-1	keratin associated protein 4-1
chr17_+_4348877	1.738	NM_001124758	SPNS2	spinster homolog 2 (Drosophila)
chr19_+_43446937	1.689	NM_001166103 NM_021102	SPINT2	serine peptidase inhibitor, Kunitz type, 2
chrX_-_50573759	1.664	NM_020717	SHROOM4	shroom family member 4
chr12_-_89873081	1.654	NM_152638	C12orf12	chromosome 12 open reading frame 12
chr15_-_42274529	1.643	NM_032892	FRMD5	FERM domain containing 5
chr14_+_76298693	1.636		VASH1	vasohibin 1
chr16_-_73798539	1.629	NM_001025200	CTRB1 CTRB2	chymotrypsinogen B1 chymotrypsinogen B2
chr21_+_36429079	1.602	NM_001236	CBR3	carbonyl reductase 3
chr19_+_43447078	1.598		SPINT2	serine peptidase inhibitor, Kunitz type, 2
chr19_+_43447262	1.597		SPINT2	serine peptidase inhibitor, Kunitz type, 2
chr1_-_27211913	1.551	NM_052943	FAM46B	family with sequence similarity 46, member B
chr2_-_241270982	1.528	NM_001102467	AQP12A AQP12B	aquaporin 12A aquaporin 12B
chr6_+_18495559	1.524	NM_182757	RNF144B	ring finger protein 144B
chr1_-_40140126	1.495	NM_001033081 NM_001033082 NM_005376	MYCL1	v-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived (avian)
chr6_+_96570565	1.492	NM_006581	FUT9	fucosyltransferase 9 (alpha (1,3) fucosyltransferase)
chr11_+_113436438	1.463	NM_001018011	ZBTB16	zinc finger and BTB domain containing 16
chr8_-_143692814	1.449	NM_015193	ARC	activity-regulated cytoskeleton-associated protein
chr2_+_33213111	1.430	NM_000627 NM_001166264 NM_001166265 NM_001166266	LTBP1	latent transforming growth factor beta binding protein 1
chr17_-_7106987	1.417	NM_001185023 NM_001307	CLDN7	claudin 7
chr15_-_42274760	1.398		FRMD5	FERM domain containing 5
chrX_-_13866366	1.360
chr2_+_241279934	1.321	NM_198998	AQP12A AQP12B	aquaporin 12A aquaporin 12B
chr16_-_87570716	1.320	NM_005187	CBFA2T3	core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr17_+_45008175	1.319	NM_007225	NXPH3	neurexophilin 3
chr9_-_96441567	1.319		FBP1	fructose-1,6-bisphosphatase 1
chr22_+_19660361	1.316		AIFM3	apoptosis-inducing factor, mitochondrion-associated, 3
chr17_+_36515166	1.292	NM_001146041	KRTAP4-9	keratin associated protein 4-9
chr11_+_76516957	1.290	NM_000260 NM_001127179 NM_001127180	MYO7A	myosin VIIA
chr7_-_143731718	1.286	NM_001080413	NOBOX	NOBOX oogenesis homeobox
chr19_+_18655487	1.257		CRTC1	CREB regulated transcription coactivator 1
chr11_-_6298284	1.254	NM_145040	PRKCDBP	protein kinase C, delta binding protein
chrX_+_110074124	1.254	NM_001128166 NM_001128167	PAK3	p21 protein (Cdc42/Rac)-activated kinase 3
chr15_+_55455994	1.249	NM_032866	CGNL1	cingulin-like 1
chr5_-_159672060	1.244	NM_024565	CCNJL	cyclin J-like
chrX_-_128616594	1.234	NM_017413	APLN	apelin
chr2_+_27358800	1.206	NM_032546 NM_187841	TRIM54	tripartite motif containing 54
chrX_-_106905545	1.199		TSC22D3	TSC22 domain family, member 3
chr17_-_36507900	1.198	NM_031960	KRTAP4-8	keratin associated protein 4-8
chrX_+_100361588	1.188	NM_001171184 NM_001939	DRP2	dystrophin related protein 2
chr7_-_28186867	1.185	NM_175061	JAZF1	JAZF zinc finger 1
chr16_+_56230707	1.181	NM_001145774	GPR56	G protein-coupled receptor 56
chr2_+_109112428	1.166	NM_001099289	SH3RF3	SH3 domain containing ring finger 3
chr21_+_46355797	1.152		COL6A2	collagen, type VI, alpha 2
chr19_-_61874934	1.151		ZNF835	zinc finger protein 835
chr22_-_37858871	1.151		CBX7	chromobox homolog 7
chr6_-_39398293	1.138	NM_001135105 NM_001135106 NM_001135107 NM_032115	KCNK16	potassium channel, subfamily K, member 16
chr9_+_37640996	1.134	NM_014907	FRMPD1	FERM and PDZ domain containing 1
chr17_-_39700960	1.127	NM_000342	SLC4A1	solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group)
chr19_-_60587414	1.119	NM_001190764	LOC388564	hypothetical protein LOC388564
chr17_-_24077246	1.115	NM_138463	TLCD1	TLC domain containing 1
chr8_-_145609737	1.110		SLC39A4	solute carrier family 39 (zinc transporter), member 4
chr11_+_70915960	1.103	NM_001012503	KRTAP5-7	keratin associated protein 5-7
chr16_+_68765428	1.102	NM_173619	CLEC18C CLEC18A CLEC18B	C-type lectin domain family 18, member C C-type lectin domain family 18, member A C-type lectin domain family 18, member B
chr19_+_40224480	1.098		HPN	hepsin
chr19_-_56229808	1.095	NM_019598 NM_145894 NM_145895	KLK12	kallikrein-related peptidase 12
chr5_-_136862130	1.093		SPOCK1	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
chr15_-_49184764	1.088	NM_207381	TNFAIP8L3	tumor necrosis factor, alpha-induced protein 8-like 3
chr1_+_181259317	1.088
chr20_+_29870836	1.085	NM_033118	MYLK2	myosin light chain kinase 2
chr7_+_116099648	1.069	NM_000245 NM_001127500	MET	met proto-oncogene (hepatocyte growth factor receptor)
chr1_-_27212035	1.064		FAM46B	family with sequence similarity 46, member B
chr19_+_14405216	1.059		PKN1	protein kinase N1
chr16_-_15742883	1.057		MYH11	myosin, heavy chain 11, smooth muscle
chr14_-_105948734	1.054		LOC100126583 IGHV4-31 IGHA1 IGHA2 IGHG1 IGHG4 IGHM	hypothetical LOC100126583 immunoglobulin heavy variable 4-31 immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant alpha 2 (A2m marker) immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant gamma 4 (G4m marker) immunoglobulin heavy constant mu
chr17_-_36559579	1.042	NM_033188	KRTAP4-5	keratin associated protein 4-5
chr9_-_135379888	1.041	NM_001080483	TMEM8C	transmembrane protein 8C
chr6_-_31188310	1.039	NM_014070	C6orf15	chromosome 6 open reading frame 15
chrX_-_106905657	1.039	NM_198057	TSC22D3	TSC22 domain family, member 3
chr19_-_51829778	1.039	NM_033258	GNG8	guanine nucleotide binding protein (G protein), gamma 8
chr16_+_68542310	1.038	NM_182619	CLEC18C CLEC18A CLEC18B	C-type lectin domain family 18, member C C-type lectin domain family 18, member A C-type lectin domain family 18, member B
chrX_+_48221323	1.037	NM_177434	FTSJ1	FtsJ homolog 1 (E. coli)
chr17_+_36599664	1.036	NM_001190460	KRTAP9-1	keratin associated protein 9-1
chrX_-_13866451	1.032		GPM6B	glycoprotein M6B
chr1_+_199975271	1.030		NAV1	neuron navigator 1
chr11_+_61204392	1.029	NM_006133	DAGLA	diacylglycerol lipase, alpha
chr11_+_1816808	1.029	NM_003282	TNNI2	troponin I type 2 (skeletal, fast)
chr5_+_169465478	1.025	NM_012188 NM_144769	FOXI1	forkhead box I1
chr17_+_37694007	1.024		STAT5A	signal transducer and activator of transcription 5A
chr1_+_100776280	1.020	NM_022049	GPR88	G protein-coupled receptor 88
chr8_-_139578246	1.019	NM_015912	FAM135B	family with sequence similarity 135, member B
chr1_-_6585268	1.004		KLHL21	kelch-like 21 (Drosophila)
chr1_+_24614831	1.002	NM_020448	NIPAL3	NIPA-like domain containing 3
chr6_-_31977747	1.002	NM_181842	ZBTB12	zinc finger and BTB domain containing 12
chr15_-_88143721	0.995		ANPEP	alanyl (membrane) aminopeptidase
chr9_+_135389698	0.986	NM_014694	ADAMTSL2	ADAMTS-like 2
chr12_+_108690199	0.985		C12orf34	chromosome 12 open reading frame 34
chr4_+_151218862	0.969	NM_001040260 NM_001040261	DCLK2	doublecortin-like kinase 2
chr12_+_47498778	0.968	NM_000725	CACNB3	calcium channel, voltage-dependent, beta 3 subunit
chr7_-_120285245	0.967		TSPAN12	tetraspanin 12
chr15_-_58671929	0.962	NM_134262	RORA	RAR-related orphan receptor A
chr17_+_26060617	0.962
chr17_-_7106497	0.948		CLDN7	claudin 7
chr11_-_16992524	0.944	NM_175058	PLEKHA7	pleckstrin homology domain containing, family A member 7
chr15_-_72981595	0.943		C15orf17	chromosome 15 open reading frame 17
chr1_-_39871226	0.943		HEYL	hairy/enhancer-of-split related with YRPW motif-like
chr7_-_135083906	0.940	NM_205855	FAM180A	family with sequence similarity 180, member A
chr14_+_76297885	0.939	NM_014909	VASH1	vasohibin 1
chr3_+_32255215	0.929		CMTM8	CKLF-like MARVEL transmembrane domain containing 8
chr2_+_233099113	0.918	NM_000751	CHRND	cholinergic receptor, nicotinic, delta
chr1_+_201364050	0.915		ADORA1	adenosine A1 receptor
chr3_+_32255158	0.914	NM_178868	CMTM8	CKLF-like MARVEL transmembrane domain containing 8
chr2_-_101134146	0.912	NM_001102426	TBC1D8	TBC1 domain family, member 8 (with GRAM domain)
chr16_+_87232501	0.912	NM_013278	IL17C	interleukin 17C
chr22_+_29122932	0.911	NM_012429 NM_033382	SEC14L2	SEC14-like 2 (S. cerevisiae)
chr11_-_684842	0.906		DEAF1	deformed epidermal autoregulatory factor 1 (Drosophila)
chr11_+_817584	0.904	NM_173584	EFCAB4A	EF-hand calcium binding domain 4A
chr5_+_66160359	0.904	NM_015183	MAST4	microtubule associated serine/threonine kinase family member 4
chr6_+_36754467	0.899		CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)
chr3_+_141879555	0.889	NM_152616	TRIM42	tripartite motif containing 42
chr19_+_40224457	0.887		HPN	hepsin
chr6_+_7672009	0.886	NM_001718	BMP6	bone morphogenetic protein 6
chr16_+_971808	0.880	NM_014587	SOX8	SRY (sex determining region Y)-box 8
chr10_-_21847126	0.879
chr5_+_159276317	0.866	NM_000679	ADRA1B	adrenergic, alpha-1B-, receptor
chr2_+_128119908	0.866	NM_001161415 NM_001161416 NM_001161417 NM_005291	GPR17	G protein-coupled receptor 17
chr10_-_61819493	0.865	NM_020987	ANK3	ankyrin 3, node of Ranvier (ankyrin G)
chr9_+_123544884	0.865	NM_138709	DAB2IP	DAB2 interacting protein
chr5_-_136862317	0.862		SPOCK1	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
chr11_-_65070625	0.859		LTBP3	latent transforming growth factor beta binding protein 3
chr12_+_129388543	0.859		PIWIL1	piwi-like 1 (Drosophila)
chr12_+_103675075	0.857		CHST11	carbohydrate (chondroitin 4) sulfotransferase 11
chr22_-_30071761	0.851		PATZ1	POZ (BTB) and AT hook containing zinc finger 1
chr2_-_80384454	0.850		LRRTM1	leucine rich repeat transmembrane neuronal 1
chr2_+_176761552	0.848	NM_024501	HOXD1	homeobox D1
chr17_+_36665161	0.846	NM_030975	KRTAP9-9	keratin associated protein 9-9
chr9_-_129869211	0.845	NM_197956	NAIF1	nuclear apoptosis inducing factor 1
chr19_+_18655483	0.841		CRTC1	CREB regulated transcription coactivator 1
chr16_-_73012740	0.840	NM_001011880	CLEC18C CLEC18A CLEC18B	C-type lectin domain family 18, member C C-type lectin domain family 18, member A C-type lectin domain family 18, member B
chrX_+_53095230	0.833	NM_018969	GPR173	G protein-coupled receptor 173
chr8_-_131483395	0.832	NM_018482	ASAP1	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
chr5_+_1254709	0.827	NM_001003841	SLC6A19	solute carrier family 6 (neutral amino acid transporter), member 19
chr5_+_71438796	0.823	NM_005909	MAP1B	microtubule-associated protein 1B
chr11_-_1026654	0.822	NM_005961	MUC6	mucin 6, oligomeric mucus/gel-forming
chr1_+_199975674	0.820		NAV1	neuron navigator 1
chr17_+_36636404	0.816	NM_031961	KRTAP9-2	keratin associated protein 9-2
chr20_+_42007949	0.813	NM_001098798	TOX2	TOX high mobility group box family member 2
chr17_-_70220605	0.809	NM_139018	CD300LF	CD300 molecule-like family member f
chr5_+_143171918	0.808	NM_021182	HMHB1	histocompatibility (minor) HB-1
chr15_-_23659329	0.803	NM_024490	ATP10A	ATPase, class V, type 10A
chr19_-_59495949	0.799	NM_001172654 NM_006865	LILRB2 LILRA3 LILRA6	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
chr1_+_18680010	0.797	NM_152375	KLHDC7A	kelch domain containing 7A
chr16_+_972064	0.795		SOX8	SRY (sex determining region Y)-box 8
chr12_+_6819635	0.793	NM_002075	GNB3	guanine nucleotide binding protein (G protein), beta polypeptide 3
chr22_-_36212160	0.791	NM_001166343 NM_002405	MFNG	MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr6_+_138524717	0.790	NM_020340	KIAA1244	KIAA1244
chrX_+_69559605	0.787	NM_001171191 NM_001171192 NM_001171193 NM_017711	GDPD2	glycerophosphodiester phosphodiesterase domain containing 2
chr13_+_112789669	0.786		MCF2L	MCF.2 cell line derived transforming sequence-like
chr22_+_18081968	0.785	NM_002688	SEPT5	septin 5
chr2_+_56265260	0.782
chr6_+_167658563	0.779	NM_031949	TTLL2	tubulin tyrosine ligase-like family, member 2
chr5_+_148501178	0.779	NM_014945	ABLIM3	actin binding LIM protein family, member 3
chr19_+_51498695	0.765	NM_152794	HIF3A	hypoxia inducible factor 3, alpha subunit
chr14_-_105851580	0.764		IGHA1 IGHA2 IGHD IGHG1	immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant alpha 2 (A2m marker) immunoglobulin heavy constant delta immunoglobulin heavy constant gamma 1 (G1m marker)
chr9_-_130980359	0.762	NM_203434	IER5L	immediate early response 5-like
chr2_-_183439515	0.762	NM_001463	FRZB	frizzled-related protein
chrX_+_70438352	0.757	NM_012278	ITGB1BP2	integrin beta 1 binding protein (melusin) 2
chr9_-_139060285	0.756		NPDC1	neural proliferation, differentiation and control, 1
chr16_+_6473759	0.756		RBFOX1	RNA binding protein, fox-1 homolog (C. elegans) 1
chr17_+_45488330	0.754	NM_002204 NM_005501	ITGA3	integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
chr1_-_23729871	0.748		E2F2	E2F transcription factor 2
chr4_-_191143017	0.747	NM_020040	TUBB4Q	tubulin, beta polypeptide 4, member Q
chr3_+_32123140	0.744		GPD1L	glycerol-3-phosphate dehydrogenase 1-like
chr2_-_216944911	0.742	NM_020814	MARCH4	membrane-associated ring finger (C3HC4) 4
chr15_+_66658626	0.740	NM_006091	CORO2B	coronin, actin binding protein, 2B
chr8_+_31010319	0.740	NM_000553	WRN	Werner syndrome, RecQ helicase-like
chr1_+_46418786	0.738		TSPAN1	tetraspanin 1
chr1_+_242281175	0.735	NM_205768	ZNF238	zinc finger protein 238
chr9_-_115101140	0.732	NM_145051	RNF183	ring finger protein 183
chr11_+_113435640	0.731	NM_006006	ZBTB16	zinc finger and BTB domain containing 16
chr12_-_68379331	0.729	NM_032735	BEST3	bestrophin 3
chr1_-_6585485	0.728	NM_014851	KLHL21	kelch-like 21 (Drosophila)
chr10_-_116382089	0.727		ABLIM1	actin binding LIM protein 1
chr1_+_1104939	0.727	NM_153254	TTLL10	tubulin tyrosine ligase-like family, member 10
chr8_-_49996353	0.722	NM_003068	SNAI2	snail homolog 2 (Drosophila)
chr8_+_145138874	0.721		GRINA	glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr17_+_45488356	0.721		ITGA3	integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
chr1_+_199975563	0.721	NM_001167738	NAV1	neuron navigator 1
chr16_-_71549149	0.719		ZFHX3	zinc finger homeobox 3
chr11_-_63689780	0.716		MACROD1	MACRO domain containing 1
chr19_-_59438411	0.715	NM_024318	LILRB3 LILRA6	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
chr14_-_105549177	0.714		IGHV4-31 IGHD IGHG3 IGHM	immunoglobulin heavy variable 4-31 immunoglobulin heavy constant delta immunoglobulin heavy constant gamma 3 (G3m marker) immunoglobulin heavy constant mu
chr19_-_2259155	0.713	NM_001101391	LINGO3	leucine rich repeat and Ig domain containing 3
chr17_+_40192072	0.712	NM_002390	ADAM11	ADAM metallopeptidase domain 11
chr2_+_10101081	0.711	NM_003597 NM_001177716	KLF11	Kruppel-like factor 11
chr12_+_48630790	0.708	NM_000486	AQP2	aquaporin 2 (collecting duct)
chr9_-_139060377	0.707		NPDC1	neural proliferation, differentiation and control, 1

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.14	1.65e-04	GO:0007165	signal transduction
1.13	2.78e-04	GO:0023052	signaling
1.33	8.65e-04	GO:0007167	enzyme linked receptor protein signaling pathway
1.11	8.18e-03	GO:0051716	cellular response to stimulus
1.33	1.82e-02	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
1.44	2.90e-02	GO:0061061	muscle structure development
1.54	3.05e-02	GO:0003012	muscle system process
1.19	3.71e-02	GO:0009966	regulation of signal transduction

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.87	6.23e-06	GO:0044449	contractile fiber part
1.80	2.15e-05	GO:0043292	contractile fiber
1.76	1.83e-04	GO:0030016	myofibril
1.81	3.42e-04	GO:0030017	sarcomere
1.42	3.45e-03	GO:0015629	actin cytoskeleton
1.06	5.21e-03	GO:0005737	cytoplasm
1.51	7.98e-03	GO:0030424	axon
1.27	1.26e-02	GO:0030054	cell junction
1.13	2.86e-02	GO:0005829	cytosol

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.08	1.74e-04	GO:0005515	protein binding
1.36	4.56e-02	GO:0003779	actin binding

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