Motif ID: TEAD1.p2

Z-value: 2.544


Transcription factors associated with TEAD1.p2:

Gene SymbolEntrez IDGene Name
TEAD1 7003 TEA domain family member 1 (SV40 transcriptional enhancer factor)
TEAD2 8463 TEA domain family member 2
TEAD3 7005 TEAD3 TEA domain family member 3
TEAD4 7004 TEAD4 TEA domain family member 4

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TEAD1chr11_+_126524270.581.8e-02Click!
TEAD2chr19_-_545574500.572.2e-02Click!
TEAD4chr12_+_29392500.562.5e-02Click!
TEAD3chr6_-_355726940.273.1e-01Click!


Activity profile for motif TEAD1.p2.

activity profile for motif TEAD1.p2


Sorted Z-values histogram for motif TEAD1.p2

Sorted Z-values for motif TEAD1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TEAD1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_132314004 5.760 NM_001901
CTGF
connective tissue growth factor
chr1_-_212791597 5.200 NM_005401
PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr4_+_184257337 5.046 NM_024949
WWC2
WW and C2 domain containing 2
chr3_-_135575925 4.711 NM_016201
AMOTL2
angiomotin like 2
chr1_-_212791467 4.557 PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr10_-_116382089 4.551 ABLIM1
actin binding LIM protein 1
chr11_-_46896484 3.956 NM_002334
LRP4
low density lipoprotein receptor-related protein 4
chr1_-_43509187 3.687 EBNA1BP2
EBNA1 binding protein 2
chrX_-_10548458 3.666 NM_000381
NM_033289
MID1

midline 1 (Opitz/BBB syndrome)

chr10_+_123862430 3.421 TACC2
transforming, acidic coiled-coil containing protein 2
chr2_-_160972606 3.350 RBMS1
RNA binding motif, single stranded interacting protein 1
chr6_-_128883125 3.186 NM_002844
NM_001135648
PTPRK

protein tyrosine phosphatase, receptor type, K

chr12_-_94708641 2.995 NM_021229
NTN4
netrin 4
chr15_+_61121806 2.988 NM_000366
NM_001018004
NM_001018005
NM_001018006
NM_001018007
NM_001018020
TPM1





tropomyosin 1 (alpha)





chr10_-_61819493 2.878 NM_020987
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr14_-_88090641 2.850 NM_007039
PTPN21
protein tyrosine phosphatase, non-receptor type 21
chr15_+_37660568 2.847 NM_003246
THBS1
thrombospondin 1
chr5_-_39460687 2.781 DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr6_+_41712907 2.741 MDFI
MyoD family inhibitor
chr1_+_24522116 2.664 NM_021180
GRHL3
grainyhead-like 3 (Drosophila)
chr1_-_12599934 2.653 NM_004753
DHRS3
dehydrogenase/reductase (SDR family) member 3
chr16_-_62573 2.550 NM_022450
RHBDF1
rhomboid 5 homolog 1 (Drosophila)
chr1_+_18680010 2.485 NM_152375
KLHDC7A
kelch domain containing 7A
chr11_-_6298284 2.481 NM_145040
PRKCDBP
protein kinase C, delta binding protein
chr19_+_39664706 2.480 NM_001080436
WTIP
Wilms tumor 1 interacting protein
chr11_-_8789457 2.462 NM_139157
ST5
suppression of tumorigenicity 5
chr6_+_167445284 2.431 NM_004367
CCR6
chemokine (C-C motif) receptor 6
chr1_-_24311212 2.417 NM_152372
MYOM3
myomesin family, member 3
chr18_-_19496590 2.349 NM_173505
ANKRD29
ankyrin repeat domain 29
chr12_+_47498778 2.329 NM_000725
CACNB3
calcium channel, voltage-dependent, beta 3 subunit
chr15_+_61122139 2.303 TPM1
tropomyosin 1 (alpha)
chr6_-_75972286 2.270 NM_004370
NM_080645
COL12A1

collagen, type XII, alpha 1

chr9_+_88953378 2.256 NM_001001709
C9orf170
chromosome 9 open reading frame 170
chr19_-_56204615 2.236 NM_012315
KLK9
kallikrein-related peptidase 9
chr12_+_26239755 2.222 NM_005086
SSPN
sarcospan (Kras oncogene-associated gene)
chr2_-_158439868 2.135 NM_001105
ACVR1
activin A receptor, type I
chr17_-_37828643 2.097 NM_012232
PTRF
polymerase I and transcript release factor
chr17_-_36347197 2.086 NM_015515
KRT23
keratin 23 (histone deacetylase inducible)
chr11_-_8788765 2.076 NM_213618
ST5
suppression of tumorigenicity 5
chr5_-_39460787 2.062 DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr6_+_123152044 2.050 SMPDL3A
sphingomyelin phosphodiesterase, acid-like 3A
chr11_-_2907169 2.041 NM_003311
PHLDA2
pleckstrin homology-like domain, family A, member 2
chr6_-_168222645 1.990 NM_024919
FRMD1
FERM domain containing 1
chr10_-_125843092 1.956 CHST15
carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
chr19_-_59568222 1.939 LAIR1
leukocyte-associated immunoglobulin-like receptor 1
chr20_-_23915431 1.936 NM_178312
GGTLC1
gamma-glutamyltransferase light chain 1
chr4_-_186970366 1.904 NM_003603
NM_001145670
SORBS2

sorbin and SH3 domain containing 2

chr19_-_59568340 1.878 LAIR1
leukocyte-associated immunoglobulin-like receptor 1
chr6_-_134538762 1.802 NM_001143678
SGK1
serum/glucocorticoid regulated kinase 1
chr3_-_129023850 1.787 NM_007283
MGLL
monoglyceride lipase
chr6_+_155453114 1.729 NM_012454
TIAM2
T-cell lymphoma invasion and metastasis 2
chr6_-_167491305 1.726 NM_005299
GPR31
G protein-coupled receptor 31
chr16_+_68765428 1.724 NM_173619
CLEC18C
CLEC18A
CLEC18B
C-type lectin domain family 18, member C
C-type lectin domain family 18, member A
C-type lectin domain family 18, member B
chr1_+_85819004 1.721 NM_001554
CYR61
cysteine-rich, angiogenic inducer, 61
chr2_+_45732416 1.694 NM_005400
PRKCE
protein kinase C, epsilon
chr20_+_36365965 1.691 NM_001725
BPI
bactericidal/permeability-increasing protein
chr11_+_124294355 1.690 NM_001037558
HEPN1
hepatocellular carcinoma, down-regulated 1
chr8_-_38505331 1.681 NM_207412
C8orf86
chromosome 8 open reading frame 86
chr6_+_144040751 1.672 NM_001100164
NM_001100165
PHACTR2

phosphatase and actin regulator 2

chr1_-_158098962 1.663 NM_001013661
VSIG8
V-set and immunoglobulin domain containing 8
chr6_-_143307976 1.644 NM_006734
HIVEP2
human immunodeficiency virus type I enhancer binding protein 2
chr1_+_181422016 1.640 LAMC2
laminin, gamma 2
chr1_-_54392030 1.640 NM_201546
CDCP2
CUB domain containing protein 2
chr6_-_42218692 1.607 NM_001164446
C6orf132
chromosome 6 open reading frame 132
chr7_-_107558021 1.601 NM_007356
LAMB4
laminin, beta 4
chr2_+_102125616 1.583 IL1R1
interleukin 1 receptor, type I
chr6_-_31007905 1.580 NM_205854
SFTA2
surfactant associated 2
chr6_-_31188310 1.576 NM_014070
C6orf15
chromosome 6 open reading frame 15
chr2_-_20075929 1.563 NM_002381
MATN3
matrilin 3
chr2_-_20075889 1.543 MATN3
matrilin 3
chr1_+_181421984 1.532 LAMC2
laminin, gamma 2
chr1_+_183970093 1.530 NM_031935
HMCN1
hemicentin 1
chr14_-_22947320 1.525 NM_002471
MYH6
myosin, heavy chain 6, cardiac muscle, alpha
chr3_-_150533948 1.510 NM_001184723
NM_138786
TM4SF18

transmembrane 4 L six family member 18

chr19_-_59568483 1.504 NM_002287
NM_021706
LAIR1

leukocyte-associated immunoglobulin-like receptor 1

chr3_+_38322430 1.499 NM_004803
SLC22A14
solute carrier family 22, member 14
chr11_-_85107569 1.495 NM_206929
SYTL2
synaptotagmin-like 2
chr15_+_94670160 1.494 NM_001145155
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr18_+_8707368 1.492 NM_015210
KIAA0802
KIAA0802
chr22_+_21318779 1.490 NM_199127
GGTLC2
gamma-glutamyltransferase light chain 2
chr11_-_85108030 1.484 NM_001162952
NM_206930
SYTL2

synaptotagmin-like 2

chr14_-_22516271 1.411 NM_198086
JUB
jub, ajuba homolog (Xenopus laevis)
chr5_-_37871685 1.408 NM_001190468
NM_001190469
GDNF

glial cell derived neurotrophic factor

chr1_-_16355013 1.406 NM_004431
EPHA2
EPH receptor A2
chr8_-_108579270 1.404 NM_001146
ANGPT1
angiopoietin 1
chr5_-_39461054 1.399 NM_001343
DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr1_+_61320213 1.380 NM_001134673
NM_005595
NFIA

nuclear factor I/A

chr7_+_134114701 1.372 NM_004342
NM_033138
NM_033157
CALD1


caldesmon 1


chr8_-_116750427 1.358 TRPS1
trichorhinophalangeal syndrome I
chr6_+_158322875 1.342 NM_003898
SYNJ2
synaptojanin 2
chr3_+_138020550 1.336 NM_001097599
NM_001097600
NM_025246
TMEM22


transmembrane protein 22


chr6_+_31190505 1.326 NM_014068
PSORS1C1
psoriasis susceptibility 1 candidate 1
chr8_-_38444398 1.316 NM_001174065
NM_001174066
NM_001174067
FGFR1


fibroblast growth factor receptor 1


chr1_+_181421796 1.303 NM_005562
NM_018891
LAMC2

laminin, gamma 2

chr6_+_158322916 1.287 SYNJ2
synaptojanin 2
chr4_-_186815116 1.280 NM_001145674
NM_001145675
SORBS2

sorbin and SH3 domain containing 2

chr16_-_73012740 1.240 NM_001011880
CLEC18C
CLEC18A
CLEC18B
C-type lectin domain family 18, member C
C-type lectin domain family 18, member A
C-type lectin domain family 18, member B
chr7_+_134114912 1.238 CALD1
caldesmon 1
chr6_+_116956868 1.235 NM_153036
FAM26D
family with sequence similarity 26, member D
chr2_+_113546365 1.217 NM_032556
IL1F10
interleukin 1 family, member 10 (theta)
chr3_+_9919295 1.215 NM_153483
IL17RE
interleukin 17 receptor E
chr1_-_201583989 1.209 FMOD
fibromodulin
chr1_+_228949752 1.207 NM_006615
NM_016452
CAPN9

calpain 9

chr12_-_47464143 1.204 NM_015270
ADCY6
adenylate cyclase 6
chr1_+_26358097 1.195 NM_024869
GRRP1
glycine/arginine rich protein 1
chr1_-_181889070 1.193 NM_203454
APOBEC4
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative)
chr6_-_75972473 1.175 COL12A1
collagen, type XII, alpha 1
chr2_+_149118791 1.172 EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr14_-_22515725 1.124 JUB
jub, ajuba homolog (Xenopus laevis)
chr6_+_158322904 1.121 SYNJ2
synaptojanin 2
chr1_-_17179694 1.098 NM_001135248
NM_002403
MFAP2

microfibrillar-associated protein 2

chr7_+_115952279 1.089 NM_001172895
CAV1
caveolin 1, caveolae protein, 22kDa
chr5_-_148422799 1.088 NM_024577
SH3TC2
SH3 domain and tetratricopeptide repeats 2
chr15_-_39973566 1.088 NM_016642
SPTBN5
spectrin, beta, non-erythrocytic 5
chr22_-_20419975 1.065 NM_013313
YPEL1
yippee-like 1 (Drosophila)
chr1_-_199704773 1.053 NM_012396
PHLDA3
pleckstrin homology-like domain, family A, member 3
chr2_-_192419896 1.036 SDPR
serum deprivation response
chr2_+_151922350 1.034 NM_007115
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr5_-_138767654 1.031 NM_194296
SPATA24
spermatogenesis associated 24
chr3_+_191588354 1.021 NM_006580
CLDN16
claudin 16
chr9_+_117955890 1.008 NM_002581
PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chr12_-_53099277 1.007 NM_002205
ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr5_+_131657964 1.007 NM_003059
SLC22A4
solute carrier family 22 (organic cation/ergothioneine transporter), member 4
chr5_+_34723420 1.004 NM_001145523
RAI14
retinoic acid induced 14
chr7_+_134114957 1.002 CALD1
caldesmon 1
chr18_+_19947314 1.001 TTC39C
tetratricopeptide repeat domain 39C
chr9_+_115970599 0.995 COL27A1
collagen, type XXVII, alpha 1
chr4_+_152417774 0.990 NM_183375
PRSS48
protease, serine, 48
chr4_-_152368492 0.988 SH3D19
SH3 domain containing 19
chr2_+_37282516 0.988 LOC100505876
hypothetical LOC100505876
chr11_-_124311106 0.983 HEPACAM
hepatic and glial cell adhesion molecule
chr5_+_76150637 0.975 F2RL1
coagulation factor II (thrombin) receptor-like 1
chr16_-_21344158 0.974 NM_130464
NPIPL3
nuclear pore complex interacting protein-like 3
chr17_+_71229110 0.972 NM_000213
NM_001005731
ITGB4

integrin, beta 4

chr12_-_53099269 0.966 ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr3_+_9919511 0.916 NM_001193380
NM_153480
IL17RE

interleukin 17 receptor E

chr6_-_31789824 0.911


chr17_+_71229191 0.907 ITGB4
integrin, beta 4
chr6_-_134538526 0.905 SGK1
serum/glucocorticoid regulated kinase 1
chr8_-_125785611 0.900 MTSS1
metastasis suppressor 1
chr11_-_9182356 0.896 DENND5A
DENN/MADD domain containing 5A
chr1_+_20269239 0.890 NM_000929
PLA2G5
phospholipase A2, group V
chr17_+_71229151 0.879 ITGB4
integrin, beta 4
chr8_+_70541412 0.877 NM_001128204
NM_015170
SULF1

sulfatase 1

chr12_-_53099203 0.876 ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr1_+_216585298 0.871 NM_001135599
NM_003238
TGFB2

transforming growth factor, beta 2

chr16_+_24174975 0.870 CACNG3
calcium channel, voltage-dependent, gamma subunit 3
chr10_-_17699309 0.868 PTPLA
protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A
chr3_-_115825742 0.864 NM_001164347
ZBTB20
zinc finger and BTB domain containing 20
chr5_+_38882017 0.837 OSMR
oncostatin M receptor
chr6_-_42017337 0.834 NM_001136125
NM_001760
CCND3

cyclin D3

chr5_+_140848905 0.829 NM_018929
NM_032407
PCDHGC5

protocadherin gamma subfamily C, 5

chr16_+_15435825 0.826 NM_033201
C16orf45
chromosome 16 open reading frame 45
chr2_+_95303947 0.819 PROM2
prominin 2
chr13_+_109936080 0.819 COL4A2
collagen, type IV, alpha 2
chr5_-_37871349 0.819 NM_199231
GDNF
glial cell derived neurotrophic factor
chr19_-_56147971 0.809 NM_001077491
NM_001077492
NM_012427
KLK5


kallikrein-related peptidase 5


chr3_-_113842553 0.806 CCDC80
coiled-coil domain containing 80
chr2_-_75641587 0.805 NM_001135032
FAM176A
family with sequence similarity 176, member A
chr19_+_55383249 0.804 MYH14
myosin, heavy chain 14, non-muscle
chr9_+_94776538 0.804 NM_033086
FGD3
FYVE, RhoGEF and PH domain containing 3
chr5_-_38631263 0.797 NM_002310
LIFR
leukemia inhibitory factor receptor alpha
chr5_-_159672060 0.786 NM_024565
CCNJL
cyclin J-like
chr2_-_75641535 0.784 FAM176A
family with sequence similarity 176, member A
chr14_-_22521544 0.776 NM_032876
JUB
jub, ajuba homolog (Xenopus laevis)
chr11_-_124311512 0.775 NM_152722
HEPACAM
hepatic and glial cell adhesion molecule
chr15_-_97366313 0.775 NM_001102612
PGPEP1L
pyroglutamyl-peptidase I-like
chr15_+_73728402 0.774 NM_153271
SNX33
sorting nexin 33
chr4_-_184480572 0.772 NM_001185149
CLDN24
claudin 24
chr6_+_31910623 0.771 NM_001040437
NM_001040438
C6orf48

chromosome 6 open reading frame 48

chr7_+_115952325 0.769 CAV1
caveolin 1, caveolae protein, 22kDa
chr3_-_113842237 0.768 CCDC80
coiled-coil domain containing 80
chr5_-_159730196 0.765 NM_031908
C1QTNF2
C1q and tumor necrosis factor related protein 2
chr2_-_233349469 0.759 NM_001172416
NM_001172417
NM_002242
KCNJ13


potassium inwardly-rectifying channel, subfamily J, member 13


chrX_-_24241352 0.750 NM_001136233
FAM48B2
family with sequence similarity 48, member B2
chr10_+_99334069 0.749 NM_001134670
NM_138413
HOGA1

4-hydroxy-2-oxoglutarate aldolase 1

chr6_+_53037754 0.749 NM_033481
FBXO9
F-box protein 9
chr3_-_113841967 0.744 CCDC80
coiled-coil domain containing 80
chr19_+_522260 0.743 NM_198591
BSG
basigin (Ok blood group)
chr3_+_125586241 0.742 KALRN
kalirin, RhoGEF kinase
chr3_-_113842350 0.739 CCDC80
coiled-coil domain containing 80
chr2_+_95303922 0.733 NM_001165977
NM_001165978
NM_144707
PROM2


prominin 2


chr11_-_65082705 0.727 LTBP3
latent transforming growth factor beta binding protein 3
chr11_+_1812115 0.725 NM_138567
SYT8
synaptotagmin VIII
chr6_+_108987703 0.721 NM_201559
FOXO3
forkhead box O3
chr3_-_10307408 0.718 NM_001134941
NM_016362
GHRL

ghrelin/obestatin prepropeptide

chr3_-_113842133 0.714 CCDC80
coiled-coil domain containing 80
chr17_+_46267603 0.712 NM_175575
WFIKKN2
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2
chr16_+_22432344 0.711 NM_001135865
LOC100132247
NPIPL3
nuclear pore complex interacting protein related gene
nuclear pore complex interacting protein-like 3
chr1_+_242281199 0.711 ZNF238
zinc finger protein 238
chr12_-_78608873 0.710 NM_002583
PAWR
PRKC, apoptosis, WT1, regulator
chr20_-_55719946 0.708 NM_199171
PMEPA1
prostate transmembrane protein, androgen induced 1
chr19_-_51666503 0.706 PNMAL1
PNMA-like 1
chr8_+_1759502 0.703 NM_014629
ARHGEF10
Rho guanine nucleotide exchange factor (GEF) 10
chr10_+_102782151 0.698 SFXN3
sideroflexin 3
chr1_-_149698516 0.697 NM_001194937
NM_001194938
NM_015100
NM_145796
POGZ



pogo transposable element with ZNF domain



chr3_-_113842255 0.696 CCDC80
coiled-coil domain containing 80
chr11_+_57123927 0.690 SERPING1
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
chr21_+_43024936 0.690 PDE9A
phosphodiesterase 9A
chr3_-_113841941 0.687 CCDC80
coiled-coil domain containing 80

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
3.65 1.37e-04 GO:0014706 striated muscle tissue development
3.48 1.80e-04 GO:0060537 muscle tissue development
2.50 4.51e-04 GO:0022603 regulation of anatomical structure morphogenesis
2.53 9.85e-04 GO:0061061 muscle structure development
2.85 1.26e-03 GO:0007517 muscle organ development
4.76 1.84e-03 GO:0055001 muscle cell development
4.96 2.72e-03 GO:0055002 striated muscle cell development
1.71 6.91e-03 GO:0048468 cell development
1.33 1.56e-02 GO:0048856 anatomical structure development
1.71 1.73e-02 GO:0040011 locomotion
2.28 2.07e-02 GO:0030029 actin filament-based process
1.83 2.13e-02 GO:0001932 regulation of protein phosphorylation
2.97 2.70e-02 GO:0042692 muscle cell differentiation
1.34 2.72e-02 GO:0048731 system development
3.60 3.20e-02 GO:0051146 striated muscle cell differentiation
1.78 3.54e-02 GO:0042325 regulation of phosphorylation
2.01 3.88e-02 GO:0016477 cell migration
1.81 3.88e-02 GO:0032989 cellular component morphogenesis
1.76 4.27e-02 GO:0019220 regulation of phosphate metabolic process
1.76 4.27e-02 GO:0051174 regulation of phosphorus metabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.48 1.06e-04 GO:0005576 extracellular region
1.27 1.98e-03 GO:0071944 cell periphery
1.63 2.00e-03 GO:0044421 extracellular region part
2.21 2.59e-03 GO:0005578 proteinaceous extracellular matrix
3.15 2.93e-03 GO:0044420 extracellular matrix part
2.61 3.71e-03 GO:0031252 cell leading edge
2.07 3.82e-03 GO:0031012 extracellular matrix
1.26 5.15e-03 GO:0005886 plasma membrane
1.38 6.63e-03 GO:0044459 plasma membrane part
2.16 9.81e-03 GO:0015629 actin cytoskeleton
3.48 2.67e-02 GO:0005604 basement membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.17 1.05e-02 GO:0005515 protein binding
8.64 1.47e-02 GO:0001968 fibronectin binding
5.99 1.60e-02 GO:0050840 extracellular matrix binding
2.07 1.95e-02 GO:0003779 actin binding
1.77 3.90e-02 GO:0008092 cytoskeletal protein binding
7.48 3.91e-02 GO:0043236 laminin binding
2.84 4.78e-02 GO:0008201 heparin binding