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• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: TFAP2B.p2

Z-value: 3.311

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr7_+_55922623	7.265		ZNF713	zinc finger protein 713
chr19_+_39664706	6.126	NM_001080436	WTIP	Wilms tumor 1 interacting protein
chr22_+_48951286	5.862	NM_001160300 NM_052839	PANX2	pannexin 2
chr11_+_359723	5.746	NM_178537	B4GALNT4	beta-1,4-N-acetyl-galactosaminyl transferase 4
chr20_-_60074237	5.715	NM_003185	TAF4	TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa
chr17_+_77582774	5.460	NM_005052	RAC3	ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
chr20_-_61933012	4.886		ZBTB46	zinc finger and BTB domain containing 46
chr3_-_130807865	4.885	NM_015103	PLXND1	plexin D1
chr8_+_1699418	4.805		CLN8	ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
chr2_+_101680594	4.655	NM_004834 NM_145686 NM_145687	MAP4K4	mitogen-activated protein kinase kinase kinase kinase 4
chr16_+_88169612	4.217	NM_014427 NM_153636	CPNE7	copine VII
chr8_+_1699276	4.072	NM_018941	CLN8	ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
chr4_-_809879	3.965	NM_006651	CPLX1	complexin 1
chr9_+_123501186	3.435		DAB2IP	DAB2 interacting protein
chr7_-_525556	3.378		PDGFA	platelet-derived growth factor alpha polypeptide
chr20_-_60375695	3.329	NM_005560	LAMA5	laminin, alpha 5
chr4_+_3264509	3.278		RGS12	regulator of G-protein signaling 12
chr20_+_8060762	3.207	NM_015192 NM_182734	PLCB1	phospholipase C, beta 1 (phosphoinositide-specific)
chr4_+_2031036	3.183	NM_178557	NAT8L	N-acetyltransferase 8-like (GCN5-related, putative)
chr2_-_110769670	3.165	NM_001164463 NM_005054	RGPD8 RGPD5	RANBP2-like and GRIP domain containing 8 RANBP2-like and GRIP domain containing 5
chr19_-_1518875	3.080	NM_001174118 NM_203304	MEX3D	mex-3 homolog D (C. elegans)
chr7_-_525336	3.070		PDGFA	platelet-derived growth factor alpha polypeptide
chr2_+_42128521	3.054	NM_138370	PKDCC	protein kinase domain containing, cytoplasmic homolog (mouse)
chr10_-_134449467	2.986	NM_177400	NKX6-2	NK6 homeobox 2
chr9_+_128128913	2.958	NM_001011703 NM_033446	FAM125B	family with sequence similarity 125, member B
chr19_+_12966970	2.828	NM_002501	NFIX	nuclear factor I/X (CCAAT-binding transcription factor)
chr15_-_27650218	2.820	NM_015307	FAM189A1	family with sequence similarity 189, member A1
chr12_+_127317900	2.791	NM_001136103	TMEM132C	transmembrane protein 132C
chr12_-_103055924	2.775	NM_006166	NFYB	nuclear transcription factor Y, beta
chr15_-_62854749	2.728	NM_194272	RBPMS2	RNA binding protein with multiple splicing 2
chr1_+_41022066	2.667	NM_004700 NM_172163	KCNQ4	potassium voltage-gated channel, KQT-like subfamily, member 4
chr11_+_1367665	2.658	NM_003957	BRSK2	BR serine/threonine kinase 2
chr3_+_12304332	2.592	NM_005037 NM_138712	PPARG	peroxisome proliferator-activated receptor gamma
chr2_-_204108151	2.592	NM_203365 NM_213589	RAPH1	Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
chr9_+_137511448	2.579	NM_014811	KIAA0649	KIAA0649
chr10_-_100017933	2.574	NM_032211	LOXL4	lysyl oxidase-like 4
chr9_+_131974506	2.507	NM_014286	NCS1	neuronal calcium sensor 1
chr7_-_5427367	2.507
chr12_+_120944174	2.505	NM_001024808 NM_020993	BCL7A	B-cell CLL/lymphoma 7A
chr6_+_167970334	2.446	NM_001040000	MLLT4	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
chr1_-_1465602	2.435	NM_001114748	C1orf70	chromosome 1 open reading frame 70
chr22_+_38720881	2.418	NM_138435	FAM83F	family with sequence similarity 83, member F
chr8_-_144583718	2.359	NM_201589	MAFA	v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)
chr19_+_540849	2.348	NM_001194	HCN2	hyperpolarization activated cyclic nucleotide-gated potassium channel 2
chr1_-_29321599	2.339	NM_001171868	TMEM200B	transmembrane protein 200B
chrX_+_9943793	2.322	NM_015691	WWC3	WWC family member 3
chr17_+_15789147	2.297		ADORA2B	adenosine A2b receptor
chr10_+_134060681	2.289	NM_001098637 NM_138499	PWWP2B	PWWP domain containing 2B
chr17_+_15788955	2.280	NM_000676	ADORA2B	adenosine A2b receptor
chr16_+_88517187	2.271	NM_006086	TUBB3	tubulin, beta 3
chr9_+_137119339	2.176		OLFM1	olfactomedin 1
chr16_+_1143241	2.160	NM_001005407 NM_021098	CACNA1H	calcium channel, voltage-dependent, T type, alpha 1H subunit
chr7_+_94374862	2.159	NM_001166160 NM_017650	PPP1R9A	protein phosphatase 1, regulatory (inhibitor) subunit 9A
chr11_-_2863536	2.148	NM_000076 NM_001122630 NM_001122631	CDKN1C	cyclin-dependent kinase inhibitor 1C (p57, Kip2)
chr1_-_232811846	2.137	NM_001077397 NM_182972	IRF2BP2	interferon regulatory factor 2 binding protein 2
chr16_+_86193993	2.137	NM_020655	JPH3	junctophilin 3
chr8_-_99906944	2.130	NM_006281	STK3	serine/threonine kinase 3
chr6_+_158164294	2.120		SNX9	sorting nexin 9
chr7_-_526005	2.116	NM_002607 NM_033023	PDGFA	platelet-derived growth factor alpha polypeptide
chr22_-_37569962	2.102	NM_014293	NPTXR	neuronal pentraxin receptor
chr9_+_137119334	2.083		OLFM1	olfactomedin 1
chr11_-_110087982	2.063		ARHGAP20	Rho GTPase activating protein 20
chr18_-_5533967	2.055	NM_012307	EPB41L3	erythrocyte membrane protein band 4.1-like 3
chr2_-_235070431	2.045	NM_005737	ARL4C	ADP-ribosylation factor-like 4C
chr2_-_160972606	2.043		RBMS1	RNA binding motif, single stranded interacting protein 1
chr14_+_99329198	2.021	NM_001008707 NM_004434	EML1	echinoderm microtubule associated protein like 1
chr22_-_41913002	2.005		TTLL12	tubulin tyrosine ligase-like family, member 12
chr22_-_27405708	1.986	NM_001145418	TTC28	tetratricopeptide repeat domain 28
chrX_+_152606945	1.969	NM_001142805 NM_005629	SLC6A8	solute carrier family 6 (neurotransmitter transporter, creatine), member 8
chr11_-_110088330	1.954	NM_020809	ARHGAP20	Rho GTPase activating protein 20
chr14_+_105012106	1.948	NM_001312	CRIP2	cysteine-rich protein 2
chr9_+_77695334	1.948	NM_001190482 NM_006200	PCSK5	proprotein convertase subtilisin/kexin type 5
chr6_-_119441045	1.946		FAM184A	family with sequence similarity 184, member A
chr2_+_154436670	1.940	NM_052917	GALNT13	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 13 (GalNAc-T13)
chr17_+_8865547	1.940	NM_004822	NTN1	netrin 1
chr1_+_2149993	1.921	NM_003036	SKI	v-ski sarcoma viral oncogene homolog (avian)
chr3_-_71857097	1.899	NM_001134651	EIF4E3	eukaryotic translation initiation factor 4E family member 3
chr6_+_158164269	1.887	NM_016224	SNX9	sorting nexin 9
chr1_+_22909916	1.868	NM_004442 NM_017449	EPHB2	EPH receptor B2
chr4_-_41848874	1.867		BEND4	BEN domain containing 4
chr22_-_49041786	1.865		MAPK12	mitogen-activated protein kinase 12
chr20_-_538909	1.853	NM_004609	TCF15	transcription factor 15 (basic helix-loop-helix)
chr19_-_17217022	1.850	NM_005234	NR2F6	nuclear receptor subfamily 2, group F, member 6
chr6_-_117193505	1.839	NM_001085480	FAM162B	family with sequence similarity 162, member B
chr2_+_104838177	1.820	NM_006236	POU3F3	POU class 3 homeobox 3
chr16_-_79395379	1.815	NM_152342	CDYL2	chromodomain protein, Y-like 2
chr1_-_31154023	1.811	NM_014654	SDC3	syndecan 3
chr6_-_18095831	1.802		KIF13A	kinesin family member 13A
chr22_+_36286350	1.784	NM_152243	CDC42EP1	CDC42 effector protein (Rho GTPase binding) 1
chr1_-_33669190	1.770		PHC2	polyhomeotic homolog 2 (Drosophila)
chr17_+_14145051	1.770	NM_006041	HS3ST3B1	heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
chr1_+_179148935	1.760	NM_020950	KIAA1614	KIAA1614
chr17_+_56831951	1.744	NM_005994	TBX2	T-box 2
chr9_-_38059082	1.723		SHB	Src homology 2 domain containing adaptor protein B
chr2_-_133144094	1.711		LYPD1	LY6/PLAUR domain containing 1
chr12_+_121885930	1.703	NM_003959	HIP1R	huntingtin interacting protein 1 related
chr10_+_59942874	1.693	NM_001080512	BICC1	bicaudal C homolog 1 (Drosophila)
chr7_+_44110470	1.691	NM_001129	AEBP1	AE binding protein 1
chr2_+_5750229	1.690	NM_003108	SOX11	SRY (sex determining region Y)-box 11
chr4_+_36923084	1.689	NM_001144990	KIAA1239	KIAA1239
chr8_+_136538739	1.676	NM_006558	KHDRBS3	KH domain containing, RNA binding, signal transduction associated 3
chr1_+_39319675	1.667	NM_012090	MACF1	microtubule-actin crosslinking factor 1
chr22_-_41913075	1.666		TTLL12	tubulin tyrosine ligase-like family, member 12
chr5_-_38592439	1.665	NM_001127671	LIFR	leukemia inhibitory factor receptor alpha
chr16_+_88422354	1.662	NM_032451	SPIRE2	spire homolog 2 (Drosophila)
chr1_+_52871603	1.659	NM_001042693	FAM159A	family with sequence similarity 159, member A
chr4_+_151218862	1.659	NM_001040260 NM_001040261	DCLK2	doublecortin-like kinase 2
chr8_+_30361485	1.653	NM_001008710 NM_001008711 NM_001008712 NM_006867	RBPMS	RNA binding protein with multiple splicing
chr17_+_75366524	1.639	NM_005189 NM_032647	CBX2	chromobox homolog 2
chr19_+_7486987	1.638	NM_018083	ZNF358	zinc finger protein 358
chr6_-_119441458	1.636	NM_024581	FAM184A	family with sequence similarity 184, member A
chr4_-_86106567	1.630	NM_014991	WDFY3	WD repeat and FYVE domain containing 3
chr12_+_107047594	1.620	NM_014653	WSCD2	WSC domain containing 2
chr11_+_12652427	1.601	NM_021961	TEAD1	TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr2_+_202607554	1.578	NM_003507	FZD7	frizzled homolog 7 (Drosophila)
chr16_-_27982277	1.571	NM_001109763	GSG1L	GSG1-like
chr11_+_76171780	1.565	NM_015516	TSKU	tsukushi small leucine rich proteoglycan homolog (Xenopus laevis)
chr12_-_45759691	1.560	NM_001143668 NM_181847	AMIGO2	adhesion molecule with Ig-like domain 2
chr11_-_16992524	1.557	NM_175058	PLEKHA7	pleckstrin homology domain containing, family A member 7
chr12_+_50271283	1.553	NM_014191	SCN8A	sodium channel, voltage gated, type VIII, alpha subunit
chr16_-_56393871	1.550		KIFC3	kinesin family member C3
chr19_-_54557450	1.537	NM_003598	TEAD2	TEA domain family member 2
chr18_-_9604555	1.535	NM_001042388 NM_005134	PPP4R1	protein phosphatase 4, regulatory subunit 1
chr7_+_101245812	1.529	NM_001913 NM_181500	CUX1	cut-like homeobox 1
chr5_-_158459006	1.527		EBF1	early B-cell factor 1
chr22_-_49042065	1.526	NM_002969	MAPK12	mitogen-activated protein kinase 12
chr19_+_4423149	1.525	NM_001001520 NM_032631	HDGFRP2	hepatoma-derived growth factor-related protein 2
chr22_+_27798887	1.519	NM_001039570 NM_032045	KREMEN1	kringle containing transmembrane protein 1
chr19_-_411995	1.514	NM_012435	SHC2	SHC (Src homology 2 domain containing) transforming protein 2
chr22_+_49459935	1.495	NM_001080420	SHANK3	SH3 and multiple ankyrin repeat domains 3
chr7_-_100262971	1.493	NM_004444	EPHB4	EPH receptor B4
chr3_-_127558747	1.484	NM_014079	KLF15	Kruppel-like factor 15
chr9_+_136358145	1.484		RXRA	retinoid X receptor, alpha
chr12_+_45759634	1.482		FAM113B	family with sequence similarity 113, member B
chr19_-_1188840	1.480	NM_152769	C19orf26	chromosome 19 open reading frame 26
chr14_+_105063975	1.474	NM_025268	TMEM121	transmembrane protein 121
chr8_-_18915443	1.474	NM_015310	PSD3	pleckstrin and Sec7 domain containing 3
chr6_+_124166767	1.473	NM_001040214 NM_153355	NKAIN2	Na+/K+ transporting ATPase interacting 2
chr1_+_66990692	1.473	NM_152665	TCTEX1D1	Tctex1 domain containing 1
chr12_+_26003218	1.470	NM_001164748 NM_007211	RASSF8	Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chr15_+_97010219	1.468	NM_000875	IGF1R	insulin-like growth factor 1 receptor
chr7_+_18093068	1.457		HDAC9	histone deacetylase 9
chr5_+_98132898	1.445	NM_001012761	RGMB	RGM domain family, member B
chr16_+_86194075	1.440		JPH3	junctophilin 3
chr9_+_136358134	1.438	NM_002957	RXRA	retinoid X receptor, alpha
chr22_+_47350781	1.436	NM_015381	FAM19A5	family with sequence similarity 19 (chemokine (C-C motif)-like), member A5
chr20_-_38751289	1.435	NM_005461	MAFB	v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)
chr7_-_5429702	1.433	NM_001080495	TNRC18	trinucleotide repeat containing 18
chr22_+_27609889	1.427	NM_032173	ZNRF3	zinc and ring finger 3
chr1_-_182273114	1.424		GLT25D2	glycosyltransferase 25 domain containing 2
chr15_-_53667800	1.423		PYGO1	pygopus homolog 1 (Drosophila)
chr1_+_66990736	1.402		TCTEX1D1	Tctex1 domain containing 1
chr17_+_35472566	1.399	NM_001190918 NM_003250 NM_199334	THRA	thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian)
chr2_+_241586927	1.391	NM_001080437	SNED1	sushi, nidogen and EGF-like domains 1
chr2_+_9264360	1.381		ASAP2	ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
chr11_-_27678551	1.380	NM_001143813 NM_001143814 NM_001709	BDNF	brain-derived neurotrophic factor
chr2_+_242289983	1.379	NM_032329	ING5	inhibitor of growth family, member 5
chr19_-_2672337	1.375	NM_145173	DIRAS1	DIRAS family, GTP-binding RAS-like 1
chr20_+_20296744	1.374	NM_002196	INSM1	insulinoma-associated 1
chr22_+_36531059	1.369	NM_005318	H1F0	H1 histone family, member 0
chr21_+_32167175	1.362	NM_014586	HUNK	hormonally up-regulated Neu-associated kinase
chr2_+_176702667	1.361	NM_019558	HOXD8	homeobox D8
chr7_-_139123906	1.359	NM_001113239 NM_022740	HIPK2	homeodomain interacting protein kinase 2
chr4_+_48187012	1.354	NM_175619	ZAR1	zygote arrest 1
chrX_-_19443299	1.354	NM_001001671	MAP3K15	mitogen-activated protein kinase kinase kinase 15
chr4_-_140420789	1.353	NM_032623	C4orf49	chromosome 4 open reading frame 49
chr15_-_27901628	1.353		TJP1	tight junction protein 1 (zona occludens 1)
chr22_-_41913076	1.351	NM_015140	TTLL12	tubulin tyrosine ligase-like family, member 12
chr7_+_44110527	1.342		AEBP1	AE binding protein 1
chr1_-_3437834	1.336		MEGF6	multiple EGF-like-domains 6
chr9_-_98421894	1.334	NM_003671 NM_033331	CDC14B	CDC14 cell division cycle 14 homolog B (S. cerevisiae)
chr20_-_61108831	1.328	NM_080606	BHLHE23	basic helix-loop-helix family, member e23
chr2_-_73193566	1.321		RAB11FIP5	RAB11 family interacting protein 5 (class I)
chr10_+_63803921	1.319	NM_014951 NM_199450 NM_199451	ZNF365	zinc finger protein 365
chr6_-_18095672	1.312	NM_001105566 NM_001105567 NM_001105568 NM_022113	KIF13A	kinesin family member 13A
chr6_+_118335381	1.312	NM_001029858	SLC35F1	solute carrier family 35, member F1
chr8_+_136539290	1.310		KHDRBS3	KH domain containing, RNA binding, signal transduction associated 3
chr19_+_56506907	1.306	NM_001101372	IGLON5	IgLON family member 5
chr18_+_46340400	1.305	NM_002747	MAPK4	mitogen-activated protein kinase 4
chr4_-_41849333	1.304		BEND4	BEN domain containing 4
chr16_+_2016807	1.303	NM_001130012 NM_004785	SLC9A3R2	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2
chr9_-_139214962	1.302	NM_001128228	TPRN	taperin
chr8_+_37672427	1.299	NM_025069	ZNF703	zinc finger protein 703
chr22_+_36531178	1.299		H1F0	H1 histone family, member 0
chr5_-_57791544	1.295	NM_006622	PLK2	polo-like kinase 2
chr6_-_72187168	1.292		C6orf155	chromosome 6 open reading frame 155
chr21_+_45649719	1.290
chr16_+_28741861	1.288		ATXN2L	ataxin 2-like
chr7_-_50828608	1.288	NM_001001555	GRB10	growth factor receptor-bound protein 10
chr7_-_50828159	1.287		GRB10	growth factor receptor-bound protein 10
chr19_-_55914837	1.287
chr10_+_83625049	1.282	NM_001010848 NM_001165972	NRG3	neuregulin 3
chr6_+_12120709	1.278	NM_002114	HIVEP1	human immunodeficiency virus type I enhancer binding protein 1
chr12_+_51777684	1.277	NM_002178	IGFBP6	insulin-like growth factor binding protein 6
chr19_-_44158130	1.270	NM_024907	FBXO17	F-box protein 17
chr2_-_73193419	1.247		RAB11FIP5	RAB11 family interacting protein 5 (class I)
chr12_+_51777715	1.247		IGFBP6	insulin-like growth factor binding protein 6
chr1_-_226661089	1.245	NM_145214	TRIM11	tripartite motif containing 11
chr16_-_65287967	1.238	NM_178818 NM_181521	CMTM4	CKLF-like MARVEL transmembrane domain containing 4
chr19_-_15421761	1.236	NM_021241	WIZ	widely interspaced zinc finger motifs

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.09	4.26e-24	GO:0009987	cellular process
1.37	5.83e-19	GO:0007399	nervous system development
1.14	6.46e-19	GO:0050794	regulation of cellular process
1.13	7.66e-18	GO:0050789	regulation of biological process
1.15	2.49e-17	GO:0044237	cellular metabolic process
1.36	2.75e-17	GO:0009653	anatomical structure morphogenesis
1.12	6.81e-17	GO:0065007	biological regulation
1.19	7.14e-17	GO:0044260	cellular macromolecule metabolic process
1.28	3.87e-16	GO:0048523	negative regulation of cellular process
1.20	4.76e-16	GO:0032502	developmental process
1.22	1.40e-15	GO:0048856	anatomical structure development
1.25	1.62e-14	GO:0048519	negative regulation of biological process
1.23	4.07e-14	GO:0048731	system development
1.19	7.22e-14	GO:0031323	regulation of cellular metabolic process
1.20	9.27e-14	GO:0007275	multicellular organismal development
1.40	2.00e-12	GO:0022008	neurogenesis
1.41	2.21e-12	GO:0048699	generation of neurons
1.11	2.80e-12	GO:0008152	metabolic process
1.25	6.68e-12	GO:0048869	cellular developmental process
1.17	6.93e-12	GO:0019222	regulation of metabolic process
1.18	1.17e-11	GO:0080090	regulation of primary metabolic process
1.12	1.62e-11	GO:0044238	primary metabolic process
1.14	1.70e-11	GO:0043170	macromolecule metabolic process
1.25	2.83e-11	GO:0030154	cell differentiation
1.52	4.27e-11	GO:0000904	cell morphogenesis involved in differentiation
1.46	1.95e-10	GO:0000902	cell morphogenesis
1.46	3.38e-10	GO:0009887	organ morphogenesis
1.18	6.49e-10	GO:0060255	regulation of macromolecule metabolic process
1.27	7.04e-10	GO:0023051	regulation of signaling
1.44	8.61e-10	GO:0032989	cellular component morphogenesis
1.21	1.41e-09	GO:0048522	positive regulation of cellular process
1.41	3.02e-09	GO:0009790	embryo development
1.24	4.38e-09	GO:0006464	protein modification process
1.35	6.54e-09	GO:0048468	cell development
1.40	6.94e-09	GO:0030182	neuron differentiation
1.20	8.33e-09	GO:0044267	cellular protein metabolic process
1.19	9.19e-09	GO:0048518	positive regulation of biological process
1.41	9.59e-09	GO:0007167	enzyme linked receptor protein signaling pathway
1.23	9.59e-09	GO:0043412	macromolecule modification
1.50	9.76e-09	GO:0048667	cell morphogenesis involved in neuron differentiation
1.27	1.47e-08	GO:0009966	regulation of signal transduction
1.46	1.58e-08	GO:0032990	cell part morphogenesis
1.16	2.46e-08	GO:0016043	cellular component organization
1.19	2.87e-08	GO:0071842	cellular component organization at cellular level
1.46	3.89e-08	GO:0048858	cell projection morphogenesis
1.16	4.12e-08	GO:0071840	cellular component organization or biogenesis
1.32	4.51e-08	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.50	4.61e-08	GO:0007409	axonogenesis
1.18	4.71e-08	GO:0071841	cellular component organization or biogenesis at cellular level
1.52	6.96e-08	GO:0048598	embryonic morphogenesis
1.44	1.47e-07	GO:0007417	central nervous system development
1.47	1.52e-07	GO:0048812	neuron projection morphogenesis
1.18	2.20e-07	GO:0051171	regulation of nitrogen compound metabolic process
1.43	2.83e-07	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
1.18	2.98e-07	GO:0010468	regulation of gene expression
1.32	3.35e-07	GO:0050793	regulation of developmental process
1.38	4.01e-07	GO:0030030	cell projection organization
1.34	8.80e-07	GO:2000026	regulation of multicellular organismal development
1.52	1.09e-06	GO:0007411	axon guidance
1.17	1.16e-06	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.17	1.16e-06	GO:0031326	regulation of cellular biosynthetic process
1.43	1.18e-06	GO:0031175	neuron projection development
1.18	1.49e-06	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.38	2.81e-06	GO:0010629	negative regulation of gene expression
1.38	2.91e-06	GO:0048666	neuron development
1.17	3.40e-06	GO:0009889	regulation of biosynthetic process
1.35	3.94e-06	GO:0045595	regulation of cell differentiation
1.49	3.95e-06	GO:0007389	pattern specification process
1.30	4.13e-06	GO:0031324	negative regulation of cellular metabolic process
1.26	4.16e-06	GO:0010604	positive regulation of macromolecule metabolic process
1.18	4.83e-06	GO:0051252	regulation of RNA metabolic process
1.29	5.16e-06	GO:0009892	negative regulation of metabolic process
1.26	5.52e-06	GO:0031325	positive regulation of cellular metabolic process
1.30	6.04e-06	GO:0010605	negative regulation of macromolecule metabolic process
1.25	7.24e-06	GO:0009893	positive regulation of metabolic process
1.39	7.34e-06	GO:0051253	negative regulation of RNA metabolic process
1.39	7.38e-06	GO:0045892	negative regulation of transcription, DNA-dependent
1.28	8.59e-06	GO:0032268	regulation of cellular protein metabolic process
1.36	8.87e-06	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
1.34	1.37e-05	GO:0010628	positive regulation of gene expression
1.56	2.28e-05	GO:0003002	regionalization
1.33	4.02e-05	GO:0031327	negative regulation of cellular biosynthetic process
1.32	4.12e-05	GO:0009890	negative regulation of biosynthetic process
1.33	5.12e-05	GO:0051254	positive regulation of RNA metabolic process
1.17	5.76e-05	GO:0006355	regulation of transcription, DNA-dependent
1.29	5.83e-05	GO:0051128	regulation of cellular component organization
1.16	8.00e-05	GO:0010556	regulation of macromolecule biosynthetic process
1.14	8.04e-05	GO:0019538	protein metabolic process
1.12	1.02e-04	GO:0023052	signaling
1.18	1.03e-04	GO:0048513	organ development
1.28	1.04e-04	GO:0006351	transcription, DNA-dependent
1.23	1.05e-04	GO:0051239	regulation of multicellular organismal process
1.32	1.21e-04	GO:0010558	negative regulation of macromolecule biosynthetic process
1.33	1.39e-04	GO:0045893	positive regulation of transcription, DNA-dependent
1.46	1.52e-04	GO:0001501	skeletal system development
1.29	1.53e-04	GO:0031399	regulation of protein modification process
1.33	1.63e-04	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.46	1.85e-04	GO:0032870	cellular response to hormone stimulus
1.13	1.86e-04	GO:0006807	nitrogen compound metabolic process
1.24	2.00e-04	GO:0051246	regulation of protein metabolic process
1.33	2.32e-04	GO:0051172	negative regulation of nitrogen compound metabolic process
1.53	2.65e-04	GO:0048568	embryonic organ development
1.42	2.72e-04	GO:0007420	brain development
1.44	2.76e-04	GO:0071495	cellular response to endogenous stimulus
1.41	3.57e-04	GO:0009792	embryo development ending in birth or egg hatching
1.44	4.30e-04	GO:0060284	regulation of cell development
1.41	4.51e-04	GO:0043009	chordate embryonic development
1.69	5.37e-04	GO:0048705	skeletal system morphogenesis
1.13	5.78e-04	GO:0034641	cellular nitrogen compound metabolic process
1.52	6.54e-04	GO:0071375	cellular response to peptide hormone stimulus
1.20	6.99e-04	GO:0065009	regulation of molecular function
1.25	8.11e-04	GO:0042127	regulation of cell proliferation
1.39	9.22e-04	GO:0000122	negative regulation of transcription from RNA polymerase II promoter
1.61	9.43e-04	GO:0048562	embryonic organ morphogenesis
1.20	1.01e-03	GO:0035556	intracellular signal transduction
1.14	1.23e-03	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.15	1.54e-03	GO:0044249	cellular biosynthetic process
1.15	1.56e-03	GO:0090304	nucleic acid metabolic process
1.12	2.01e-03	GO:0007165	signal transduction
1.10	2.25e-03	GO:0051716	cellular response to stimulus
1.34	2.52e-03	GO:0045944	positive regulation of transcription from RNA polymerase II promoter
1.23	2.54e-03	GO:0006793	phosphorus metabolic process
1.23	2.54e-03	GO:0006796	phosphate metabolic process
1.11	2.64e-03	GO:0051179	localization
1.13	2.82e-03	GO:0051234	establishment of localization
1.22	3.03e-03	GO:0010646	regulation of cell communication
1.42	3.49e-03	GO:0022603	regulation of anatomical structure morphogenesis
1.26	4.31e-03	GO:0051173	positive regulation of nitrogen compound metabolic process
1.26	4.41e-03	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.12	4.85e-03	GO:0006810	transport
1.21	4.94e-03	GO:0051649	establishment of localization in cell
1.54	4.98e-03	GO:0032869	cellular response to insulin stimulus
1.63	5.21e-03	GO:0030111	regulation of Wnt receptor signaling pathway
1.14	5.95e-03	GO:0009058	biosynthetic process
1.24	6.86e-03	GO:0031328	positive regulation of cellular biosynthetic process
1.20	8.82e-03	GO:0044248	cellular catabolic process
1.16	8.90e-03	GO:0016070	RNA metabolic process
1.19	1.03e-02	GO:0051641	cellular localization
1.46	1.11e-02	GO:0048011	nerve growth factor receptor signaling pathway
1.22	1.15e-02	GO:0032774	RNA biosynthetic process
1.28	1.25e-02	GO:0051726	regulation of cell cycle
1.38	1.27e-02	GO:0044257	cellular protein catabolic process
1.16	1.31e-02	GO:0034645	cellular macromolecule biosynthetic process
1.33	1.40e-02	GO:0010648	negative regulation of cell communication
1.38	1.43e-02	GO:0043632	modification-dependent macromolecule catabolic process
1.38	1.61e-02	GO:0019941	modification-dependent protein catabolic process
1.25	1.69e-02	GO:0006468	protein phosphorylation
1.25	1.70e-02	GO:0010557	positive regulation of macromolecule biosynthetic process
1.73	1.75e-02	GO:0060828	regulation of canonical Wnt receptor signaling pathway
1.37	1.78e-02	GO:0051603	proteolysis involved in cellular protein catabolic process
1.32	1.88e-02	GO:0023057	negative regulation of signaling
1.23	1.95e-02	GO:0009891	positive regulation of biosynthetic process
1.35	2.01e-02	GO:0051056	regulation of small GTPase mediated signal transduction
1.74	2.10e-02	GO:0021915	neural tube development
1.39	2.28e-02	GO:0048729	tissue morphogenesis
1.44	2.50e-02	GO:0002009	morphogenesis of an epithelium
1.16	2.54e-02	GO:0009059	macromolecule biosynthetic process
1.29	2.63e-02	GO:0044265	cellular macromolecule catabolic process
1.52	2.73e-02	GO:0009952	anterior/posterior pattern formation
1.35	2.80e-02	GO:0010551	regulation of gene-specific transcription from RNA polymerase II promoter
1.32	3.11e-02	GO:0032583	regulation of gene-specific transcription
1.23	3.20e-02	GO:0016310	phosphorylation
1.96	3.38e-02	GO:0001649	osteoblast differentiation
1.68	3.55e-02	GO:0021537	telencephalon development
1.20	3.56e-02	GO:0043067	regulation of programmed cell death
1.37	3.92e-02	GO:0006511	ubiquitin-dependent protein catabolic process
1.20	4.19e-02	GO:0010941	regulation of cell death
1.49	4.27e-02	GO:0030900	forebrain development
1.26	4.61e-02	GO:0009057	macromolecule catabolic process
1.84	4.98e-02	GO:0001889	liver development

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.10	3.51e-34	GO:0005622	intracellular
1.10	3.91e-32	GO:0044424	intracellular part
1.12	7.22e-22	GO:0005737	cytoplasm
1.10	3.69e-21	GO:0043226	organelle
1.10	4.59e-21	GO:0043229	intracellular organelle
1.11	4.94e-20	GO:0043231	intracellular membrane-bounded organelle
1.11	5.01e-20	GO:0043227	membrane-bounded organelle
1.13	2.50e-12	GO:0005634	nucleus
1.11	6.31e-10	GO:0044444	cytoplasmic part
1.12	9.31e-10	GO:0044446	intracellular organelle part
1.12	9.60e-10	GO:0044422	organelle part
1.03	3.88e-08	GO:0044464	cell part
1.03	4.29e-08	GO:0005623	cell
1.19	2.17e-07	GO:0044428	nuclear part
1.18	1.31e-05	GO:0031981	nuclear lumen
1.21	4.55e-05	GO:0005654	nucleoplasm
1.16	5.92e-05	GO:0070013	intracellular organelle lumen
1.15	1.02e-04	GO:0043233	organelle lumen
1.15	1.18e-04	GO:0031974	membrane-enclosed lumen
1.56	1.32e-04	GO:0031252	cell leading edge
1.16	2.27e-04	GO:0005829	cytosol
1.59	3.24e-04	GO:0005912	adherens junction
1.90	5.28e-04	GO:0031256	leading edge membrane
1.55	6.57e-04	GO:0070161	anchoring junction
1.14	1.30e-03	GO:0031090	organelle membrane
1.26	7.14e-03	GO:0030054	cell junction
1.40	8.26e-03	GO:0005667	transcription factor complex
1.15	1.93e-02	GO:0012505	endomembrane system
1.30	1.98e-02	GO:0043005	neuron projection
1.10	2.15e-02	GO:0043234	protein complex
1.22	2.77e-02	GO:0044451	nucleoplasm part
1.18	3.05e-02	GO:0005794	Golgi apparatus
1.65	3.83e-02	GO:0031461	cullin-RING ubiquitin ligase complex

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.15	1.74e-25	GO:0005515	protein binding
1.08	1.54e-21	GO:0005488	binding
1.31	1.19e-08	GO:0001071	nucleic acid binding transcription factor activity
1.31	1.19e-08	GO:0003700	sequence-specific DNA binding transcription factor activity
1.27	1.54e-06	GO:0030528	transcription regulator activity
1.48	6.41e-06	GO:0016563	transcription activator activity
1.17	1.20e-05	GO:0000166	nucleotide binding
1.29	1.39e-05	GO:0016301	kinase activity
1.30	2.19e-05	GO:0016773	phosphotransferase activity, alcohol group as acceptor
1.30	6.00e-05	GO:0043565	sequence-specific DNA binding
1.31	1.26e-04	GO:0004672	protein kinase activity
1.16	7.84e-04	GO:0017076	purine nucleotide binding
1.15	1.89e-03	GO:0032553	ribonucleotide binding
1.15	1.89e-03	GO:0032555	purine ribonucleotide binding
1.11	2.18e-03	GO:0003676	nucleic acid binding
1.14	2.29e-03	GO:0003677	DNA binding
1.08	3.32e-03	GO:0003824	catalytic activity
1.15	3.61e-03	GO:0035639	purine ribonucleoside triphosphate binding
1.47	3.81e-03	GO:0000975	regulatory region DNA binding
1.47	3.81e-03	GO:0001067	regulatory region nucleic acid binding
1.47	3.81e-03	GO:0044212	transcription regulatory region DNA binding
1.24	4.03e-03	GO:0019899	enzyme binding
1.22	4.10e-03	GO:0016772	transferase activity, transferring phosphorus-containing groups
1.32	4.51e-03	GO:0004674	protein serine/threonine kinase activity
1.17	4.58e-03	GO:0030554	adenyl nucleotide binding
1.16	1.04e-02	GO:0032559	adenyl ribonucleotide binding
1.45	1.20e-02	GO:0010843	promoter binding
1.15	1.20e-02	GO:0016740	transferase activity
1.66	1.38e-02	GO:0000981	sequence-specific DNA binding RNA polymerase II transcription factor activity
1.15	2.27e-02	GO:0005524	ATP binding
1.66	3.56e-02	GO:0003705	sequence-specific enhancer binding RNA polymerase II transcription factor activity

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