Motif ID: TFAP4.p2

Z-value: 2.031


Transcription factors associated with TFAP4.p2:

Gene SymbolEntrez IDGene Name
TFAP4 7023 transcription factor AP-4 (activating enhancer binding protein 4)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TFAP4chr16_-_42626960.391.3e-01Click!


Activity profile for motif TFAP4.p2.

activity profile for motif TFAP4.p2


Sorted Z-values histogram for motif TFAP4.p2

Sorted Z-values for motif TFAP4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TFAP4.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr22_+_20068039 3.080 NM_001128635
 RIMBP3B
RIMS binding protein 3B
chr2_+_128119908 2.656 NM_001161415
NM_001161416
NM_001161417
NM_005291
 GPR17



G protein-coupled receptor 17



chr21_+_36429079 2.390 NM_001236
 CBR3
carbonyl reductase 3
chr22_-_20235372 2.320 NM_001128635
 RIMBP3B
RIMS binding protein 3B
chr5_+_129268352 2.039 NM_175856
 CHSY3
chondroitin sulfate synthase 3
chr7_-_27136876 1.908 NM_002141
 HOXA4
homeobox A4
chr1_+_43769065 1.835 NM_002840
NM_130440
 PTPRF

protein tyrosine phosphatase, receptor type, F

chr17_-_36528113 1.799 NM_033059
 KRTAP4-11
keratin associated protein 4-11
chr1_-_93919789 1.758 NM_003567
 BCAR3
breast cancer anti-estrogen resistance 3
chr2_+_159533329 1.747 NM_001145909
NM_033394
 TANC1

tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1

chr19_-_56841819 1.743 NM_001098612
 SIGLEC14
sialic acid binding Ig-like lectin 14
chr6_-_167491305 1.699 NM_005299
 GPR31
G protein-coupled receptor 31
chr2_+_187266899 1.557 NM_177454
 FAM171B
family with sequence similarity 171, member B
chr1_+_208472817 1.429 NM_019605
 SERTAD4
SERTA domain containing 4
chr6_-_160599779 1.321 NM_003058
 SLC22A2
solute carrier family 22 (organic cation transporter), member 2
chr19_-_55156118 1.278 NM_001135163
NM_052884
 SIGLEC11

sialic acid binding Ig-like lectin 11

chr5_-_112658200 1.274 MCC
mutated in colorectal cancers
chr18_-_53621277 1.240 NM_005603
 ATP8B1
ATPase, aminophospholipid transporter, class I, type 8B, member 1
chr19_-_56825400 1.214 NM_003830
 SIGLEC5
sialic acid binding Ig-like lectin 5
chr7_+_153633127 1.170 NM_001936
 DPP6
dipeptidyl-peptidase 6

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 4 of 4 entries
enrichment   p-value GO term description
1.41 1.61e-02 GO:0006915 apoptosis
1.39 2.51e-02 GO:0012501 programmed cell death
1.38 5.86e-03 GO:0016265 death
1.38 6.43e-03 GO:0008219 cell death

Gene overrepresentation in compartment category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
3.13 1.64e-10 GO:0045095 keratin filament
2.00 5.75e-05 GO:0005882 intermediate filament
1.94 2.95e-05 GO:0045111 intermediate filament cytoskeleton
1.57 3.52e-02 GO:0000323 lytic vacuole
1.57 3.52e-02 GO:0005764 lysosome
1.52 3.27e-02 GO:0005773 vacuole
1.10 1.82e-04 GO:0005737 cytoplasm
1.10 3.76e-02 GO:0044444 cytoplasmic part

Gene overrepresentation in function category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
1.10 2.01e-03 GO:0005515 protein binding