Motif ID: TFDP1.p2

Z-value: 2.634


Transcription factors associated with TFDP1.p2:

Gene SymbolEntrez IDGene Name
TFDP1 7027 transcription factor Dp-1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TFDP1chr13_+_113286979-0.552.6e-02Click!


Activity profile for motif TFDP1.p2.

activity profile for motif TFDP1.p2


Sorted Z-values histogram for motif TFDP1.p2

Sorted Z-values for motif TFDP1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TFDP1.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr22_+_27609889 2.798 NM_032173
ZNRF3
zinc and ring finger 3
chr19_-_15421761 2.535 NM_021241
WIZ
widely interspaced zinc finger motifs
chr1_-_32002222 2.505 NM_001703
BAI2
brain-specific angiogenesis inhibitor 2
chr7_+_116099648 2.339 NM_000245
NM_001127500
MET

met proto-oncogene (hepatocyte growth factor receptor)

chr11_-_46896484 2.086 NM_002334
LRP4
low density lipoprotein receptor-related protein 4
chr9_-_98421894 2.016 NM_003671
NM_033331
CDC14B

CDC14 cell division cycle 14 homolog B (S. cerevisiae)

chr14_+_20608179 1.907 NM_018071
ARHGEF40
Rho guanine nucleotide exchange factor (GEF) 40
chr3_+_160964574 1.821 SCHIP1
schwannomin interacting protein 1
chr3_-_51976428 1.772 NM_020418
NM_001174100
NM_033008
PCBP4


poly(rC) binding protein 4


chr22_-_34754343 1.717 NM_001082578
NM_001082579
RBFOX2

RNA binding protein, fox-1 homolog (C. elegans) 2

chr6_+_45497796 1.661 NM_004348
RUNX2
runt-related transcription factor 2
chr3_-_187025501 1.661 NM_001007225
NM_006548
IGF2BP2

insulin-like growth factor 2 mRNA binding protein 2

chr1_+_2149993 1.632 NM_003036
SKI
v-ski sarcoma viral oncogene homolog (avian)
chr19_+_39664706 1.626 NM_001080436
WTIP
Wilms tumor 1 interacting protein
chr7_-_525556 1.584 PDGFA
platelet-derived growth factor alpha polypeptide
chr2_-_171725150 1.563 TLK1
tousled-like kinase 1
chr3_-_187025438 1.544 IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr1_-_223907283 1.511 NM_001008493
NM_018212
ENAH

enabled homolog (Drosophila)

chr3_-_185461768 1.497 NM_033259
CAMK2N2
calcium/calmodulin-dependent protein kinase II inhibitor 2
chr5_+_52812236 1.494 NM_006350
NM_013409
FST

follistatin

chr6_-_99904251 1.460 NM_032511
C6orf168
chromosome 6 open reading frame 168
chr21_-_39607288 1.427 BRWD1
bromodomain and WD repeat domain containing 1
chr2_-_168812132 1.403 NM_013233
STK39
serine threonine kinase 39
chr5_+_52812165 1.402 FST
follistatin
chr22_+_27798887 1.389 NM_001039570
NM_032045
KREMEN1

kringle containing transmembrane protein 1

chr12_-_87498225 1.357 NM_000899
NM_003994
KITLG

KIT ligand

chr9_+_129414287 1.301 NM_001032221
NM_003165
STXBP1

syntaxin binding protein 1

chr10_+_59942874 1.293 NM_001080512
BICC1
bicaudal C homolog 1 (Drosophila)
chr2_+_178767317 1.292 NM_032523
OSBPL6
oxysterol binding protein-like 6
chr5_+_72957736 1.289 NM_001080479
NM_001177693
RGNEF

190 kDa guanine nucleotide exchange factor

chr7_-_525336 1.280 PDGFA
platelet-derived growth factor alpha polypeptide
chr13_-_76499270 1.277 FBXL3
F-box and leucine-rich repeat protein 3
chr8_+_30361485 1.277 NM_001008710
NM_001008711
NM_001008712
NM_006867
RBPMS



RNA binding protein with multiple splicing



chr1_+_64983312 1.258 NM_018211
RAVER2
ribonucleoprotein, PTB-binding 2
chr9_-_111300350 1.237 NM_001145368
NM_002829
PTPN3

protein tyrosine phosphatase, non-receptor type 3

chr12_+_120944174 1.215 NM_001024808
NM_020993
BCL7A

B-cell CLL/lymphoma 7A

chr14_+_104402626 1.189 NM_001112726
NM_015005
KIAA0284

KIAA0284

chr7_-_28186671 1.188 JAZF1
JAZF zinc finger 1
chr1_+_232107170 1.185 NM_173508
SLC35F3
solute carrier family 35, member F3
chr19_+_47480445 1.161 NM_015125
CIC
capicua homolog (Drosophila)
chr2_+_159533329 1.161 NM_001145909
NM_033394
TANC1

tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1

chr7_+_33911636 1.138 NM_133468
BMPER
BMP binding endothelial regulator
chr12_-_51912101 1.129 NM_000966
RARG
retinoic acid receptor, gamma
chr2_+_242146791 1.128 NM_032515
BOK
BCL2-related ovarian killer
chr6_-_18095672 1.126 NM_001105566
NM_001105567
NM_001105568
NM_022113
KIF13A



kinesin family member 13A



chr15_-_58671929 1.110 NM_134262
RORA
RAR-related orphan receptor A
chr20_-_60375695 1.107 NM_005560
LAMA5
laminin, alpha 5
chr11_+_10283171 1.093 NM_001124
ADM
adrenomedullin
chr1_-_232811846 1.086 NM_001077397
NM_182972
IRF2BP2

interferon regulatory factor 2 binding protein 2

chr6_-_91063181 1.081 NM_021813
BACH2
BTB and CNC homology 1, basic leucine zipper transcription factor 2
chr16_-_65287967 1.077 NM_178818
NM_181521
CMTM4

CKLF-like MARVEL transmembrane domain containing 4

chr4_+_72271218 1.055 NM_001098484
NM_001134742
SLC4A4

solute carrier family 4, sodium bicarbonate cotransporter, member 4

chr17_+_14145051 1.043 NM_006041
HS3ST3B1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
chr4_+_3264509 1.042 RGS12
regulator of G-protein signaling 12
chr1_+_28867876 1.032 GMEB1
glucocorticoid modulatory element binding protein 1
chr19_-_17217022 1.027 NM_005234
NR2F6
nuclear receptor subfamily 2, group F, member 6
chr20_-_60074237 1.027 NM_003185
TAF4
TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa
chr2_-_224612177 1.021 NM_001136528
NM_006216
SERPINE2

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2

chr9_-_112840064 1.017 NM_001401
NM_057159
LPAR1

lysophosphatidic acid receptor 1

chr16_-_8964751 1.013 NM_003470
USP7
ubiquitin specific peptidase 7 (herpes virus-associated)
chr1_-_226202210 1.008 NM_003395
WNT9A
wingless-type MMTV integration site family, member 9A
chr2_-_160972606 1.007 RBMS1
RNA binding motif, single stranded interacting protein 1
chr17_+_77582774 0.976 NM_005052
RAC3
ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
chr9_+_128128913 0.974 NM_001011703
NM_033446
FAM125B

family with sequence similarity 125, member B

chr4_+_85723080 0.960 NM_001263
CDS1
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
chr14_-_88328848 0.948 NM_183387
EML5
echinoderm microtubule associated protein like 5
chr10_-_25052549 0.948 NM_020824
ARHGAP21
Rho GTPase activating protein 21
chr7_-_28186867 0.947 NM_175061
JAZF1
JAZF zinc finger 1
chr19_-_36531958 0.939 NM_020856
TSHZ3
teashirt zinc finger homeobox 3
chr9_-_109291575 0.916 KLF4
Kruppel-like factor 4 (gut)
chr1_+_19843261 0.913 NM_005380
NBL1
neuroblastoma, suppression of tumorigenicity 1
chr14_-_88953059 0.913 NM_005197
FOXN3
forkhead box N3
chr17_-_6400470 0.909 NM_001165966
NM_031220
PITPNM3

PITPNM family member 3

chr15_-_27901628 0.906 TJP1
tight junction protein 1 (zona occludens 1)
chr2_+_206255597 0.904 NRP2
neuropilin 2
chr18_-_72336133 0.899 NM_014643
ZNF516
zinc finger protein 516
chr12_-_24606616 0.898 NM_152989
SOX5
SRY (sex determining region Y)-box 5
chr22_+_48966394 0.894 TRABD
TraB domain containing
chr11_-_94603857 0.893 NM_144665
SESN3
sestrin 3
chr20_-_62071584 0.890 NM_020713
ZNF512B
zinc finger protein 512B
chr16_-_62573 0.884 NM_022450
RHBDF1
rhomboid 5 homolog 1 (Drosophila)
chr1_+_26895108 0.884 NM_006015
NM_139135
ARID1A

AT rich interactive domain 1A (SWI-like)

chr19_+_56506907 0.879 NM_001101372
IGLON5
IgLON family member 5
chr17_+_24742068 0.877 NM_020791
TAOK1
TAO kinase 1
chr11_+_67984758 0.866 NM_001164160
NM_001164161
NM_001164162
NM_001164163
NM_001164164
NM_018312
PPP6R3





protein phosphatase 6, regulatory subunit 3





chr10_-_123347493 0.862 NM_000141
NM_001144917
NM_001144918
NM_001144919
NM_022970
FGFR2




fibroblast growth factor receptor 2




chr18_+_65219114 0.862 NM_152721
DOK6
docking protein 6
chr2_-_47986160 0.859 NM_001190274
FBXO11
F-box protein 11
chr2_+_36436316 0.850 CRIM1
cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr11_+_12652427 0.847 NM_021961
TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr9_-_79835970 0.847 NM_002072
GNAQ
guanine nucleotide binding protein (G protein), q polypeptide
chr6_-_128883125 0.841 NM_002844
NM_001135648
PTPRK

protein tyrosine phosphatase, receptor type, K

chr18_-_12874140 0.841 NM_002828
NM_080422
NM_080423
PTPN2


protein tyrosine phosphatase, non-receptor type 2


chr7_-_100262971 0.834 NM_004444
EPHB4
EPH receptor B4
chr9_-_109291866 0.821 NM_004235
KLF4
Kruppel-like factor 4 (gut)
chr9_+_95378492 0.821 NM_005392
PHF2
PHD finger protein 2
chr12_-_103055924 0.818 NM_006166
NFYB
nuclear transcription factor Y, beta
chr4_-_86106567 0.815 NM_014991
WDFY3
WD repeat and FYVE domain containing 3
chr16_+_51722285 0.813 CHD9
chromodomain helicase DNA binding protein 9
chr4_-_123092358 0.811 NM_001130698
TRPC3
transient receptor potential cation channel, subfamily C, member 3
chr8_+_37672427 0.806 NM_025069
ZNF703
zinc finger protein 703
chr9_+_102275310 0.803 NM_003692
TMEFF1
transmembrane protein with EGF-like and two follistatin-like domains 1
chr2_-_235070431 0.802 NM_005737
ARL4C
ADP-ribosylation factor-like 4C
chr2_+_46378405 0.801 EPAS1
endothelial PAS domain protein 1
chr17_+_31975611 0.799 GGNBP2
gametogenetin binding protein 2
chr2_+_206255376 0.798 NM_003872
NM_018534
NM_201264
NM_201266
NM_201267
NM_201279
NRP2





neuropilin 2





chr17_-_40263124 0.798 NM_005497
GJC1
gap junction protein, gamma 1, 45kDa
chr4_-_119493322 0.793 NM_003619
PRSS12
protease, serine, 12 (neurotrypsin, motopsin)
chr1_+_109594163 0.784 NM_001408
CELSR2
cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)
chr18_-_28304392 0.778 NM_022751
FAM59A
family with sequence similarity 59, member A
chr12_+_64504408 0.774 NM_003483
NM_003484
HMGA2

high mobility group AT-hook 2

chr14_-_102593264 0.771


chr10_+_124211353 0.770 HTRA1
HtrA serine peptidase 1
chr1_+_182622987 0.770 C1orf21
chromosome 1 open reading frame 21
chr22_+_39677319 0.768 RBX1
ring-box 1, E3 ubiquitin protein ligase
chr14_-_60260211 0.768 NM_017420
SIX4
SIX homeobox 4
chr3_-_71196696 0.766 FOXP1
forkhead box P1
chr4_+_184257337 0.763 NM_024949
WWC2
WW and C2 domain containing 2
chr3_+_30623376 0.756 TGFBR2
transforming growth factor, beta receptor II (70/80kDa)
chr22_-_32646325 0.752 NM_004737
NM_133642
LARGE

like-glycosyltransferase

chr11_+_129823667 0.747 NM_139055
ADAMTS15
ADAM metallopeptidase with thrombospondin type 1 motif, 15
chr1_+_64012154 0.741 NM_001083592
NM_005012
ROR1

receptor tyrosine kinase-like orphan receptor 1

chr13_-_76499297 0.738 NM_012158
FBXL3
F-box and leucine-rich repeat protein 3
chr14_+_93710401 0.736 NM_020958
NM_058237
PPP4R4

protein phosphatase 4, regulatory subunit 4

chr5_-_9599157 0.730 NM_003966
SEMA5A
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr4_-_99798563 0.729 NM_005723
TSPAN5
tetraspanin 5
chr3_-_52694554 0.728 NM_018313
PBRM1
polybromo 1
chr12_+_2032649 0.723 NM_000719
NM_001129827
NM_001129829
NM_001129830
NM_001129831
NM_001129832
NM_001129833
NM_001129834
NM_001129835
NM_001129836
NM_001129837
NM_001129838
NM_001129839
NM_001129840
NM_001129841
NM_001129842
NM_001129843
NM_001129844
NM_001129846
NM_001167623
NM_001167624
NM_001167625
NM_199460
CACNA1C






















calcium channel, voltage-dependent, L type, alpha 1C subunit






















chr18_-_44189625 0.716 ZBTB7C
zinc finger and BTB domain containing 7C
chr10_-_75304225 0.716 NM_001222
NM_172169
NM_172171
NM_172173
NM_172170
CAMK2G




calcium/calmodulin-dependent protein kinase II gamma




chr14_-_88090641 0.715 NM_007039
PTPN21
protein tyrosine phosphatase, non-receptor type 21
chr22_+_39677274 0.714 NM_014248
RBX1
ring-box 1, E3 ubiquitin protein ligase
chr9_+_130354490 0.705 NM_001130438
NM_001195532
NM_003127
SPTAN1


spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)


chr7_+_139124502 0.703 NM_001130966
NM_001166254
TBXAS1

thromboxane A synthase 1 (platelet)

chr15_+_94674849 0.699 NM_021005
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr12_+_8741746 0.698 NM_020734
RIMKLB
ribosomal modification protein rimK-like family member B
chr1_+_28867801 0.689 NM_006582
NM_024482
GMEB1

glucocorticoid modulatory element binding protein 1

chr3_-_114898003 0.689 NM_001009899
KIAA2018
KIAA2018
chr19_+_12966970 0.688 NM_002501
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr7_-_526005 0.687 NM_002607
NM_033023
PDGFA

platelet-derived growth factor alpha polypeptide

chr6_-_136913235 0.686 MAP7
microtubule-associated protein 7
chr7_-_44891471 0.685 NM_033224
PURB
purine-rich element binding protein B
chr11_-_133786935 0.685 NM_018644
NM_054025
B3GAT1

beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)

chr15_-_43602293 0.684 NM_013309
SLC30A4
solute carrier family 30 (zinc transporter), member 4
chr18_-_9604454 0.683 PPP4R1
protein phosphatase 4, regulatory subunit 1
chr20_-_3714905 0.682 NM_001810
CENPB
centromere protein B, 80kDa
chr8_+_95977135 0.681 C8orf38
chromosome 8 open reading frame 38
chr1_+_85819004 0.676 NM_001554
CYR61
cysteine-rich, angiogenic inducer, 61
chr9_+_136358134 0.676 NM_002957
RXRA
retinoid X receptor, alpha
chr2_+_20510312 0.675 NM_004040
RHOB
ras homolog gene family, member B
chr14_-_102593384 0.673 NM_006035
CDC42BPB
CDC42 binding protein kinase beta (DMPK-like)
chr5_+_172000793 0.672 NM_001142651
NEURL1B
neuralized homolog 1B (Drosophila)
chr21_-_39607415 0.671 NM_001007246
NM_018963
NM_033656
BRWD1


bromodomain and WD repeat domain containing 1


chr5_-_16989371 0.668 NM_012334
MYO10
myosin X
chr13_-_105985313 0.666 NM_004093
EFNB2
ephrin-B2
chr5_-_111782637 0.665 NM_022140
EPB41L4A
erythrocyte membrane protein band 4.1 like 4A
chr19_+_40451720 0.664 NM_003367
NM_207291
USF2

upstream transcription factor 2, c-fos interacting

chrX_-_41667174 0.664 NM_001126054
NM_001126055
NM_003688
CASK


calcium/calmodulin-dependent serine protein kinase (MAGUK family)


chr3_-_13896618 0.663 NM_004625
WNT7A
wingless-type MMTV integration site family, member 7A
chr7_-_42243318 0.662 GLI3
GLI family zinc finger 3
chr2_-_61551403 0.661 USP34
ubiquitin specific peptidase 34
chr2_-_183611470 0.660 NM_013436
NM_205842
NCKAP1

NCK-associated protein 1

chr1_+_33494745 0.657 NM_152493
ZNF362
zinc finger protein 362
chr2_+_85051942 0.656 KCMF1
potassium channel modulatory factor 1
chr8_-_67687980 0.655 NM_001080416
NM_001144755
MYBL1

LOC645895
v-myb myeloblastosis viral oncogene homolog (avian)-like 1

hypothetical LOC645895
chr19_+_40451842 0.654 USF2
upstream transcription factor 2, c-fos interacting
chr7_-_127833231 0.653 NM_001142573
NM_001142574
NM_001142575
IMPDH1


IMP (inosine 5'-monophosphate) dehydrogenase 1


chr11_-_44928803 0.652 NM_001076787
NM_006034
TP53I11

tumor protein p53 inducible protein 11

chr3_-_15875932 0.650 NM_015199
ANKRD28
ankyrin repeat domain 28
chr22_-_45311730 0.650 NM_014246
CELSR1
cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila)
chr2_-_25749786 0.649 NM_021907
NM_033147
NM_033148
NM_183360
NM_183361
DTNB




dystrobrevin, beta




chr1_+_182622751 0.646 NM_030806
C1orf21
chromosome 1 open reading frame 21
chr16_-_2204776 0.645 NM_001042371
PGP
phosphoglycolate phosphatase
chr3_-_126257425 0.645 NM_020733
HEG1
HEG homolog 1 (zebrafish)
chr2_+_28469864 0.643 FOSL2
FOS-like antigen 2
chr9_+_131974506 0.641 NM_014286
NCS1
neuronal calcium sensor 1
chr10_+_86078136 0.641 NM_018999
FAM190B
family with sequence similarity 190, member B
chr8_+_98857190 0.640 LAPTM4B
lysosomal protein transmembrane 4 beta
chr2_-_109728693 0.640 SEPT10
septin 10
chr17_+_35472566 0.640 NM_001190918
NM_003250
NM_199334
THRA


thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian)


chr12_-_28014151 0.637 NM_198964
NM_198966
PTHLH

parathyroid hormone-like hormone

chr1_+_218768146 0.637 MARK1
MAP/microtubule affinity-regulating kinase 1
chr2_-_109728958 0.636 NM_144710
NM_178584
SEPT10

septin 10

chr3_+_50167851 0.633 NM_004186
SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr3_+_37878647 0.633 NM_001008392
NM_005808
CTDSPL

CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like

chr16_-_23068010 0.627 NM_020718
USP31
ubiquitin specific peptidase 31
chr4_-_122063118 0.619 NM_018699
PRDM5
PR domain containing 5
chr19_+_38979502 0.619 NM_001129994
NM_001129995
NM_024076
KCTD15


potassium channel tetramerisation domain containing 15


chr3_-_137953876 0.619 NM_005862
STAG1
stromal antigen 1
chr3_+_52694975 0.618 NM_014366
NM_206825
NM_206826
GNL3


guanine nucleotide binding protein-like 3 (nucleolar)


chr6_+_132170847 0.618 NM_006208
ENPP1
ectonucleotide pyrophosphatase/phosphodiesterase 1
chr11_-_114880275 0.617 NM_001098517
NM_014333
CADM1

cell adhesion molecule 1

chr19_-_52426055 0.615 NM_014417
BBC3
BCL2 binding component 3
chr4_-_122213018 0.615 NM_024574
C4orf31
chromosome 4 open reading frame 31
chr15_+_83092854 0.614 ZNF592
zinc finger protein 592
chr1_+_16046945 0.612 NM_015001
SPEN
spen homolog, transcriptional regulator (Drosophila)
chr2_-_183610992 0.609 NCKAP1
NCK-associated protein 1
chr1_+_6767968 0.609 NM_001195563
NM_015215
CAMTA1

calmodulin binding transcription activator 1

chr9_-_93225780 0.608 NFIL3
nuclear factor, interleukin 3 regulated
chr4_+_26471410 0.608 NM_001169117
NM_001169118
NM_020860
STIM2


stromal interaction molecule 2



Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.26 6.87e-38 GO:0044260 cellular macromolecule metabolic process
1.11 2.50e-35 GO:0009987 cellular process
1.18 7.72e-32 GO:0044237 cellular metabolic process
1.20 1.24e-25 GO:0043170 macromolecule metabolic process
1.36 4.92e-25 GO:0006464 protein modification process
1.29 1.61e-23 GO:0044267 cellular protein metabolic process
1.16 4.70e-23 GO:0044238 primary metabolic process
1.28 6.23e-23 GO:0071842 cellular component organization at cellular level
1.33 5.67e-22 GO:0043412 macromolecule modification
1.14 3.41e-21 GO:0008152 metabolic process
1.23 4.52e-21 GO:0016043 cellular component organization
1.26 5.59e-21 GO:0071841 cellular component organization or biogenesis at cellular level
1.22 3.85e-19 GO:0071840 cellular component organization or biogenesis
1.13 8.19e-19 GO:0050794 regulation of cellular process
1.12 4.57e-16 GO:0050789 regulation of biological process
1.31 5.31e-16 GO:0006996 organelle organization
1.23 9.10e-16 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.25 1.01e-15 GO:0048522 positive regulation of cellular process
1.22 5.83e-14 GO:0048518 positive regulation of biological process
1.18 1.25e-13 GO:0031323 regulation of cellular metabolic process
1.10 3.27e-13 GO:0065007 biological regulation
1.28 6.46e-13 GO:0034645 cellular macromolecule biosynthetic process
1.20 7.94e-13 GO:0019538 protein metabolic process
1.28 1.13e-12 GO:0009059 macromolecule biosynthetic process
1.30 1.76e-12 GO:0009966 regulation of signal transduction
1.24 1.97e-12 GO:0048523 negative regulation of cellular process
1.18 2.02e-12 GO:0060255 regulation of macromolecule metabolic process
1.17 2.12e-12 GO:0019222 regulation of metabolic process
1.19 3.17e-12 GO:0006807 nitrogen compound metabolic process
1.19 3.19e-12 GO:0034641 cellular nitrogen compound metabolic process
1.18 5.27e-12 GO:0080090 regulation of primary metabolic process
1.23 2.00e-11 GO:0090304 nucleic acid metabolic process
1.21 2.18e-11 GO:0044249 cellular biosynthetic process
1.34 2.27e-11 GO:0007049 cell cycle
1.32 8.37e-11 GO:0010604 positive regulation of macromolecule metabolic process
1.31 1.17e-10 GO:0031325 positive regulation of cellular metabolic process
1.16 1.17e-10 GO:0032502 developmental process
1.30 1.59e-10 GO:0009893 positive regulation of metabolic process
1.21 1.68e-10 GO:0048519 negative regulation of biological process
1.26 1.98e-10 GO:0023051 regulation of signaling
1.20 4.86e-10 GO:0009058 biosynthetic process
1.33 7.40e-10 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.16 1.55e-09 GO:0007275 multicellular organismal development
1.26 3.40e-09 GO:0009653 anatomical structure morphogenesis
1.34 4.38e-09 GO:0006351 transcription, DNA-dependent
1.17 8.13e-09 GO:0048856 anatomical structure development
1.40 8.66e-09 GO:0030030 cell projection organization
1.33 9.66e-09 GO:0048468 cell development
1.31 1.44e-08 GO:0006793 phosphorus metabolic process
1.31 1.44e-08 GO:0006796 phosphate metabolic process
1.44 1.99e-08 GO:0031175 neuron projection development
1.36 2.23e-08 GO:0006468 protein phosphorylation
1.41 2.29e-08 GO:0000278 mitotic cell cycle
1.39 2.33e-08 GO:0051276 chromosome organization
1.34 2.41e-08 GO:0022402 cell cycle process
1.18 2.44e-08 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.25 2.69e-08 GO:0007399 nervous system development
1.43 8.32e-08 GO:0000904 cell morphogenesis involved in differentiation
1.37 8.87e-08 GO:0051254 positive regulation of RNA metabolic process
1.31 1.11e-07 GO:0010605 negative regulation of macromolecule metabolic process
1.17 1.12e-07 GO:0051171 regulation of nitrogen compound metabolic process
1.34 1.16e-07 GO:0051173 positive regulation of nitrogen compound metabolic process
1.34 1.36e-07 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.38 1.63e-07 GO:0000902 cell morphogenesis
1.30 1.68e-07 GO:0032774 RNA biosynthetic process
1.36 2.07e-07 GO:0010628 positive regulation of gene expression
1.25 2.24e-07 GO:0035556 intracellular signal transduction
1.49 2.40e-07 GO:0051301 cell division
1.37 3.41e-07 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.16 3.51e-07 GO:0048731 system development
1.35 4.11e-07 GO:0022403 cell cycle phase
1.37 4.32e-07 GO:0045893 positive regulation of transcription, DNA-dependent
1.45 4.73e-07 GO:0007409 axonogenesis
1.35 5.15e-07 GO:0009890 negative regulation of biosynthetic process
1.29 5.26e-07 GO:0009892 negative regulation of metabolic process
1.36 5.62e-07 GO:0010558 negative regulation of macromolecule biosynthetic process
1.18 7.03e-07 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.17 7.68e-07 GO:0010468 regulation of gene expression
1.43 9.56e-07 GO:0048667 cell morphogenesis involved in neuron differentiation
1.38 1.02e-06 GO:0048666 neuron development
1.31 1.13e-06 GO:0033554 cellular response to stress
1.34 1.21e-06 GO:0031327 negative regulation of cellular biosynthetic process
1.20 1.21e-06 GO:0010467 gene expression
1.40 1.34e-06 GO:0032990 cell part morphogenesis
1.29 1.45e-06 GO:0022008 neurogenesis
1.39 1.78e-06 GO:0044265 cellular macromolecule catabolic process
1.42 1.84e-06 GO:0048812 neuron projection morphogenesis
1.30 1.90e-06 GO:0016265 death
1.21 2.01e-06 GO:0016070 RNA metabolic process
1.35 2.19e-06 GO:0032989 cellular component morphogenesis
1.30 2.26e-06 GO:0008219 cell death
1.36 2.27e-06 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.35 2.28e-06 GO:0007167 enzyme linked receptor protein signaling pathway
1.39 2.93e-06 GO:0048858 cell projection morphogenesis
1.29 2.94e-06 GO:0031324 negative regulation of cellular metabolic process
1.32 4.96e-06 GO:0010557 positive regulation of macromolecule biosynthetic process
1.29 6.29e-06 GO:0016310 phosphorylation
1.35 6.42e-06 GO:0051172 negative regulation of nitrogen compound metabolic process
1.49 6.98e-06 GO:0048285 organelle fission
1.16 7.86e-06 GO:0010556 regulation of macromolecule biosynthetic process
1.29 8.74e-06 GO:0048699 generation of neurons
1.47 9.84e-06 GO:0043632 modification-dependent macromolecule catabolic process
1.17 1.05e-05 GO:0051252 regulation of RNA metabolic process
1.47 1.07e-05 GO:0019941 modification-dependent protein catabolic process
1.43 1.22e-05 GO:0007264 small GTPase mediated signal transduction
1.46 1.28e-05 GO:0070647 protein modification by small protein conjugation or removal
1.23 1.50e-05 GO:0033036 macromolecule localization
1.46 1.52e-05 GO:0051603 proteolysis involved in cellular protein catabolic process
1.33 1.97e-05 GO:0051726 regulation of cell cycle
1.31 1.98e-05 GO:0012501 programmed cell death
1.47 2.16e-05 GO:0000087 M phase of mitotic cell cycle
1.51 2.75e-05 GO:0016567 protein ubiquitination
1.46 2.83e-05 GO:0006511 ubiquitin-dependent protein catabolic process
1.48 3.07e-05 GO:0000280 nuclear division
1.48 3.07e-05 GO:0007067 mitosis
1.33 3.07e-05 GO:0009057 macromolecule catabolic process
1.28 3.52e-05 GO:0031328 positive regulation of cellular biosynthetic process
1.25 3.54e-05 GO:0008104 protein localization
1.43 3.62e-05 GO:0016568 chromatin modification
1.28 3.93e-05 GO:0009891 positive regulation of biosynthetic process
1.44 4.54e-05 GO:0044257 cellular protein catabolic process
1.30 4.91e-05 GO:0006915 apoptosis
1.17 4.97e-05 GO:0048869 cellular developmental process
1.25 5.42e-05 GO:0032268 regulation of cellular protein metabolic process
1.48 5.64e-05 GO:0032446 protein modification by small protein conjugation
1.33 5.71e-05 GO:0010629 negative regulation of gene expression
1.15 5.74e-05 GO:0031326 regulation of cellular biosynthetic process
1.11 6.39e-05 GO:0051716 cellular response to stimulus
1.38 6.70e-05 GO:0000279 M phase
1.14 7.90e-05 GO:0009889 regulation of biosynthetic process
1.36 8.79e-05 GO:0006325 chromatin organization
1.35 9.91e-05 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.43 1.15e-04 GO:0007411 axon guidance
1.30 1.16e-04 GO:0030182 neuron differentiation
1.12 1.42e-04 GO:0007165 signal transduction
1.12 1.47e-04 GO:0023052 signaling
1.34 1.52e-04 GO:0051253 negative regulation of RNA metabolic process
1.27 1.72e-04 GO:0046907 intracellular transport
1.29 1.84e-04 GO:0019220 regulation of phosphate metabolic process
1.29 1.84e-04 GO:0051174 regulation of phosphorus metabolic process
1.34 2.00e-04 GO:0010942 positive regulation of cell death
1.22 2.09e-04 GO:0044248 cellular catabolic process
1.51 2.26e-04 GO:0048011 nerve growth factor receptor signaling pathway
1.33 2.36e-04 GO:0045892 negative regulation of transcription, DNA-dependent
1.16 2.79e-04 GO:0030154 cell differentiation
1.34 2.86e-04 GO:0043068 positive regulation of programmed cell death
1.16 3.03e-04 GO:0006355 regulation of transcription, DNA-dependent
1.33 4.23e-04 GO:0043065 positive regulation of apoptosis
1.25 4.46e-04 GO:0050793 regulation of developmental process
1.26 4.48e-04 GO:0051128 regulation of cellular component organization
1.22 5.29e-04 GO:0051246 regulation of protein metabolic process
1.26 6.16e-04 GO:0031399 regulation of protein modification process
1.30 7.06e-04 GO:0006259 DNA metabolic process
1.25 7.87e-04 GO:0045184 establishment of protein localization
1.28 8.21e-04 GO:0045595 regulation of cell differentiation
1.20 8.35e-04 GO:0051641 cellular localization
1.28 9.71e-04 GO:0042325 regulation of phosphorylation
1.11 1.02e-03 GO:0051179 localization
1.38 1.32e-03 GO:0030163 protein catabolic process
1.33 1.40e-03 GO:0072358 cardiovascular system development
1.33 1.40e-03 GO:0072359 circulatory system development
1.27 1.42e-03 GO:0009790 embryo development
1.21 2.46e-03 GO:0022607 cellular component assembly
1.69 3.83e-03 GO:0040029 regulation of gene expression, epigenetic
1.25 4.28e-03 GO:0071844 cellular component assembly at cellular level
1.21 4.52e-03 GO:0010646 regulation of cell communication
1.32 4.71e-03 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.61 4.85e-03 GO:0006403 RNA localization
1.61 5.56e-03 GO:0050657 nucleic acid transport
1.61 5.56e-03 GO:0050658 RNA transport
1.61 5.56e-03 GO:0051236 establishment of RNA localization
1.36 5.86e-03 GO:0018193 peptidyl-amino acid modification
1.23 6.25e-03 GO:0015031 protein transport
1.21 6.33e-03 GO:0010941 regulation of cell death
1.21 6.60e-03 GO:0043067 regulation of programmed cell death
1.41 6.75e-03 GO:0035295 tube development
1.63 7.71e-03 GO:0051028 mRNA transport
1.21 8.81e-03 GO:0042981 regulation of apoptosis
1.76 1.05e-02 GO:0007173 epidermal growth factor receptor signaling pathway
1.26 1.10e-02 GO:0001932 regulation of protein phosphorylation
1.25 1.31e-02 GO:0065003 macromolecular complex assembly
1.37 1.45e-02 GO:0051325 interphase
1.17 1.55e-02 GO:0009056 catabolic process
1.15 1.58e-02 GO:0048583 regulation of response to stimulus
1.21 1.58e-02 GO:0042127 regulation of cell proliferation
1.48 1.79e-02 GO:0006913 nucleocytoplasmic transport
1.38 1.96e-02 GO:0006366 transcription from RNA polymerase II promoter
1.89 1.97e-02 GO:0033044 regulation of chromosome organization
1.47 2.07e-02 GO:0016569 covalent chromatin modification
1.53 2.31e-02 GO:0015931 nucleobase, nucleoside, nucleotide and nucleic acid transport
1.37 2.41e-02 GO:0051329 interphase of mitotic cell cycle
1.40 2.59e-02 GO:0009100 glycoprotein metabolic process
1.23 2.69e-02 GO:2000026 regulation of multicellular organismal development
1.95 3.19e-02 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process
1.47 3.36e-02 GO:0016570 histone modification
1.47 3.36e-02 GO:0051169 nuclear transport
1.37 3.57e-02 GO:0001944 vasculature development
1.46 3.82e-02 GO:0006260 DNA replication
1.28 3.97e-02 GO:0009967 positive regulation of signal transduction
1.33 3.98e-02 GO:0006917 induction of apoptosis
1.34 4.05e-02 GO:0033043 regulation of organelle organization
1.33 4.91e-02 GO:0012502 induction of programmed cell death

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.14 2.65e-76 GO:0005622 intracellular
1.14 4.73e-73 GO:0044424 intracellular part
1.15 1.88e-53 GO:0043226 organelle
1.15 6.41e-53 GO:0043229 intracellular organelle
1.17 5.13e-52 GO:0043227 membrane-bounded organelle
1.17 1.26e-51 GO:0043231 intracellular membrane-bounded organelle
1.16 2.55e-41 GO:0005737 cytoplasm
1.22 6.56e-41 GO:0005634 nucleus
1.35 1.33e-30 GO:0044428 nuclear part
1.19 8.34e-29 GO:0044446 intracellular organelle part
1.18 1.98e-28 GO:0044422 organelle part
1.36 7.82e-27 GO:0031981 nuclear lumen
1.43 1.00e-26 GO:0005654 nucleoplasm
1.05 3.85e-23 GO:0005623 cell
1.05 5.48e-23 GO:0044464 cell part
1.29 1.14e-22 GO:0070013 intracellular organelle lumen
1.15 4.12e-22 GO:0044444 cytoplasmic part
1.28 3.20e-21 GO:0043233 organelle lumen
1.28 5.10e-21 GO:0031974 membrane-enclosed lumen
1.29 1.42e-19 GO:0005829 cytosol
1.40 3.89e-12 GO:0044451 nucleoplasm part
1.43 2.85e-10 GO:0005694 chromosome
1.24 2.20e-09 GO:0012505 endomembrane system
1.44 5.02e-09 GO:0044427 chromosomal part
1.16 6.11e-08 GO:0043228 non-membrane-bounded organelle
1.16 6.11e-08 GO:0043232 intracellular non-membrane-bounded organelle
1.60 1.52e-07 GO:0000228 nuclear chromosome
1.13 6.93e-07 GO:0032991 macromolecular complex
1.17 7.71e-07 GO:0031090 organelle membrane
1.14 1.57e-06 GO:0043234 protein complex
1.88 6.12e-06 GO:0000790 nuclear chromatin
1.35 1.30e-05 GO:0000139 Golgi membrane
1.58 2.15e-05 GO:0044454 nuclear chromosome part
1.49 2.71e-05 GO:0000785 chromatin
1.31 4.27e-05 GO:0044431 Golgi apparatus part
1.28 4.78e-05 GO:0015630 microtubule cytoskeleton
1.77 7.24e-05 GO:0016585 chromatin remodeling complex
1.53 1.21e-04 GO:0031252 cell leading edge
1.58 1.70e-04 GO:0005912 adherens junction
1.22 2.84e-04 GO:0005794 Golgi apparatus
1.46 2.89e-04 GO:0016604 nuclear body
1.51 1.04e-03 GO:0070161 anchoring junction
1.41 2.18e-03 GO:0005635 nuclear envelope
1.55 2.50e-03 GO:0031301 integral to organelle membrane
1.52 3.39e-03 GO:0031965 nuclear membrane
1.45 4.59e-03 GO:0005819 spindle
1.33 5.23e-03 GO:0005815 microtubule organizing center
1.82 1.02e-02 GO:0034708 methyltransferase complex
1.82 1.02e-02 GO:0035097 histone methyltransferase complex
1.15 1.22e-02 GO:0005856 cytoskeleton
1.31 1.54e-02 GO:0048471 perinuclear region of cytoplasm
1.37 1.65e-02 GO:0005667 transcription factor complex
1.91 1.76e-02 GO:0008287 protein serine/threonine phosphatase complex
2.33 3.67e-02 GO:0030530 heterogeneous nuclear ribonucleoprotein complex
1.44 3.89e-02 GO:0031300 intrinsic to organelle membrane
1.67 4.29e-02 GO:0000922 spindle pole
2.03 4.94e-02 GO:0005720 nuclear heterochromatin
1.45 4.99e-02 GO:0000775 chromosome, centromeric region

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.20 7.39e-54 GO:0005515 protein binding
1.09 1.55e-35 GO:0005488 binding
1.19 7.60e-14 GO:0003676 nucleic acid binding
1.21 1.81e-11 GO:0000166 nucleotide binding
1.33 3.37e-10 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.19 2.66e-09 GO:0003677 DNA binding
1.30 3.25e-09 GO:0030528 transcription regulator activity
1.22 4.55e-09 GO:0016740 transferase activity
1.33 1.48e-08 GO:0016301 kinase activity
1.33 6.25e-08 GO:0019899 enzyme binding
1.33 9.13e-08 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.36 1.98e-07 GO:0004672 protein kinase activity
1.41 6.20e-07 GO:0019904 protein domain specific binding
1.19 2.04e-06 GO:0035639 purine ribonucleoside triphosphate binding
1.51 2.38e-06 GO:0016881 acid-amino acid ligase activity
1.18 5.25e-06 GO:0017076 purine nucleotide binding
1.31 5.34e-06 GO:0043565 sequence-specific DNA binding
1.18 5.49e-06 GO:0032553 ribonucleotide binding
1.18 5.49e-06 GO:0032555 purine ribonucleotide binding
1.52 9.05e-06 GO:0019787 small conjugating protein ligase activity
1.09 2.04e-05 GO:0003824 catalytic activity
1.44 3.42e-05 GO:0016879 ligase activity, forming carbon-nitrogen bonds
1.24 3.87e-05 GO:0001071 nucleic acid binding transcription factor activity
1.24 3.87e-05 GO:0003700 sequence-specific DNA binding transcription factor activity
1.37 4.03e-05 GO:0004674 protein serine/threonine kinase activity
1.51 4.96e-05 GO:0004842 ubiquitin-protein ligase activity
1.41 2.20e-04 GO:0016564 transcription repressor activity
1.42 2.64e-04 GO:0008134 transcription factor binding
2.05 4.80e-04 GO:0046332 SMAD binding
1.24 6.11e-04 GO:0003723 RNA binding
1.32 7.88e-04 GO:0030695 GTPase regulator activity
1.17 1.12e-03 GO:0005524 ATP binding
1.31 1.24e-03 GO:0060589 nucleoside-triphosphatase regulator activity
1.16 1.72e-03 GO:0030554 adenyl nucleotide binding
1.16 2.22e-03 GO:0032559 adenyl ribonucleotide binding
1.51 2.62e-03 GO:0004721 phosphoprotein phosphatase activity
1.30 2.99e-03 GO:0016874 ligase activity
1.33 3.97e-03 GO:0000988 protein binding transcription factor activity
1.33 3.97e-03 GO:0000989 transcription factor binding transcription factor activity
1.32 5.34e-03 GO:0003712 transcription cofactor activity
1.13 5.35e-03 GO:0008270 zinc ion binding
1.35 8.00e-03 GO:0016563 transcription activator activity
1.24 9.41e-03 GO:0046983 protein dimerization activity
1.43 9.62e-03 GO:0000975 regulatory region DNA binding
1.43 9.62e-03 GO:0001067 regulatory region nucleic acid binding
1.43 9.62e-03 GO:0044212 transcription regulatory region DNA binding
1.51 1.02e-02 GO:0008022 protein C-terminus binding
1.36 4.48e-02 GO:0016791 phosphatase activity
1.40 4.89e-02 GO:0010843 promoter binding