Motif ID: TP53.p2

Z-value: 1.116


Transcription factors associated with TP53.p2:

Gene SymbolEntrez IDGene Name
TP53 7157 tumor protein p53

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TP53chr17_-_75314560.136.4e-01Click!


Activity profile for motif TP53.p2.

activity profile for motif TP53.p2


Sorted Z-values histogram for motif TP53.p2

Sorted Z-values for motif TP53.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TP53.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_+_36752244 3.569 NM_078467
CDKN1A
cyclin-dependent kinase inhibitor 1A (p21, Cip1)
chr1_+_3597092 1.655 NM_001126240
NM_001126241
NM_001126242
TP73


tumor protein p73


chr6_-_138470160 1.356 NM_022121
PERP
PERP, TP53 apoptosis effector
chr16_-_66558197 1.266 NM_001145964
SLC12A4
solute carrier family 12 (potassium/chloride transporters), member 4
chr6_+_24511123 1.089 NM_020662
MRS2
MRS2 magnesium homeostasis factor homolog (S. cerevisiae)
chr15_-_50608296 1.050 NM_000259
NM_001142495
MYO5A

myosin VA (heavy chain 12, myoxin)

chr1_-_2447848 0.968 NM_018216
PANK4
pantothenate kinase 4
chr6_+_116798791 0.961 NM_013352
DSE
dermatan sulfate epimerase
chr22_-_18687511 0.948 NM_033257
DGCR6L
DiGeorge syndrome critical region gene 6-like
chr11_-_72986738 0.890 NM_015159
FAM168A
family with sequence similarity 168, member A
chr10_-_30388439 0.890 NM_020848
KIAA1462
KIAA1462
chr7_-_74705276 0.885 NM_001145064
GATSL2
GATS protein-like 2
chr6_-_167491305 0.787 NM_005299
GPR31
G protein-coupled receptor 31
chr1_+_153799637 0.763 LOC645676
hypothetical LOC645676
chr1_+_32443822 0.753 NM_001160042
NM_018134
IQCC

IQ motif containing C

chr20_-_32354736 0.746 NM_000687
AHCY
adenosylhomocysteinase
chr14_-_30959487 0.717 HEATR5A
HEAT repeat containing 5A
chr2_-_26058941 0.707 NM_002254
KIF3C
kinesin family member 3C
chr16_-_14695930 0.637 NM_003561
PLA2G10
phospholipase A2, group X
chr4_+_148872902 0.636 NM_024605
ARHGAP10
Rho GTPase activating protein 10

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
3.95 9.33e-03 GO:0009116 nucleoside metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 12 of 12 entries
enrichment   p-value GO term description
1.65 8.93e-03 GO:0005794 Golgi apparatus
1.40 1.81e-02 GO:0005829 cytosol
1.37 4.91e-02 GO:0031090 organelle membrane
1.35 1.82e-09 GO:0044444 cytoplasmic part
1.23 1.85e-07 GO:0005737 cytoplasm
1.20 4.07e-02 GO:0044446 intracellular organelle part
1.14 1.36e-02 GO:0043227 membrane-bounded organelle
1.14 1.62e-02 GO:0043231 intracellular membrane-bounded organelle
1.12 1.76e-03 GO:0044424 intracellular part
1.12 2.47e-02 GO:0043226 organelle
1.12 2.69e-02 GO:0043229 intracellular organelle
1.11 3.82e-03 GO:0005622 intracellular

Gene overrepresentation in function category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
21.83 2.07e-03 GO:0004594 pantothenate kinase activity