Motif ID: ZBTB16.p2

Z-value: 1.859


Transcription factors associated with ZBTB16.p2:

Gene SymbolEntrez IDGene Name
ZBTB16 7704 zinc finger and BTB domain containing 16

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ZBTB16chr11_+_113436438-0.439.4e-02Click!


Activity profile for motif ZBTB16.p2.

activity profile for motif ZBTB16.p2


Sorted Z-values histogram for motif ZBTB16.p2

Sorted Z-values for motif ZBTB16.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZBTB16.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr12_-_10453409 2.826 NM_013431
 KLRC4-KLRK1
KLRC4
KLRC4-KLRK1 read-through transcript
killer cell lectin-like receptor subfamily C, member 4
chr5_+_57823017 2.798 NM_152687
 GAPT
GRB2-binding adaptor protein, transmembrane
chr9_-_21340885 2.734 NM_021002
 IFNA6
interferon, alpha 6
chr4_-_77176163 2.564 NM_005409
 CXCL11
chemokine (C-X-C motif) ligand 11
chr7_-_92693716 2.553 NM_001039372
 HEPACAM2
HEPACAM family member 2
chr4_+_74520796 2.223 NM_001134
 AFP
alpha-fetoprotein
chr4_-_38460983 2.174 NM_001017388
NM_001195106
NM_001195107
NM_001195108
NM_030956
 TLR10




toll-like receptor 10




chr9_-_21375258 2.079 NM_000605
 IFNA2
interferon, alpha 2
chr12_-_9987277 2.072 LOC100506159
hypothetical LOC100506159
chr18_+_59733724 2.057 NM_005024
 SERPINB10
serpin peptidase inhibitor, clade B (ovalbumin), member 10
chr7_+_99263571 2.027 NM_022820
NM_057095
NM_057096
 CYP3A43


cytochrome P450, family 3, subfamily A, polypeptide 43


chr2_-_135498716 1.997 NM_001018046
NM_025052
 YSK4

YSK4 Sps1/Ste20-related kinase homolog (S. cerevisiae)

chr5_-_176760242 1.995 NM_001029886
 PFN3
profilin 3
chr16_-_70168449 1.942 NM_000353
 TAT
tyrosine aminotransferase
chr17_+_29621352 1.877 NM_006273
 CCL7
chemokine (C-C motif) ligand 7
chr14_+_28311740 1.862 C14orf23
chromosome 14 open reading frame 23
chr12_+_10351683 1.814 NM_002262
NM_007334
 KLRD1

killer cell lectin-like receptor subfamily D, member 1

chr4_-_90978469 1.791 NM_001146055
 SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr9_+_21430439 1.725 NM_024013
 IFNA1
interferon, alpha 1
chr15_-_72446979 1.637 NM_000781
 CYP11A1
cytochrome P450, family 11, subfamily A, polypeptide 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 20 entries
enrichment   p-value GO term description
5.51 3.55e-04 GO:0060338 regulation of type I interferon-mediated signaling pathway
3.69 1.95e-03 GO:0060337 type I interferon-mediated signaling pathway
3.69 1.95e-03 GO:0071357 cellular response to type I interferon
3.63 2.53e-03 GO:0034340 response to type I interferon
3.28 4.22e-02 GO:0001959 regulation of cytokine-mediated signaling pathway
2.56 2.42e-03 GO:0009615 response to virus
2.47 2.43e-10 GO:0007608 sensory perception of smell
2.44 2.26e-11 GO:0007606 sensory perception of chemical stimulus
2.04 1.55e-04 GO:0051707 response to other organism
1.98 1.21e-02 GO:0031347 regulation of defense response
1.92 2.12e-04 GO:0009607 response to biotic stimulus
1.91 2.02e-08 GO:0007600 sensory perception
1.87 2.35e-02 GO:0045087 innate immune response
1.85 6.30e-03 GO:0050776 regulation of immune response
1.77 5.07e-05 GO:0006955 immune response
1.66 1.00e-03 GO:0006952 defense response
1.51 4.66e-04 GO:0050877 neurological system process
1.48 6.28e-03 GO:0002376 immune system process
1.40 7.00e-03 GO:0003008 system process
1.17 6.64e-03 GO:0050896 response to stimulus

Gene overrepresentation in compartment category:

Showing 1 to 6 of 6 entries
enrichment   p-value GO term description
1.77 1.33e-06 GO:0005615 extracellular space
1.61 1.40e-05 GO:0044421 extracellular region part
1.42 1.11e-05 GO:0005576 extracellular region
1.27 7.29e-06 GO:0005886 plasma membrane
1.27 9.67e-06 GO:0071944 cell periphery
1.14 9.74e-03 GO:0044425 membrane part

Gene overrepresentation in function category:

Showing 1 to 9 of 9 entries
enrichment   p-value GO term description
11.12 7.49e-05 GO:0005132 interferon-alpha/beta receptor binding
2.56 1.21e-11 GO:0004984 olfactory receptor activity
2.34 1.39e-03 GO:0005126 cytokine receptor binding
2.24 2.80e-03 GO:0005125 cytokine activity
1.95 1.81e-10 GO:0004930 G-protein coupled receptor activity
1.67 1.95e-08 GO:0004888 transmembrane receptor activity
1.56 3.10e-08 GO:0004872 receptor activity
1.44 3.97e-06 GO:0004871 signal transducer activity
1.44 3.97e-06 GO:0060089 molecular transducer activity