Motif ID: ZBTB6.p2

Z-value: 1.531


Transcription factors associated with ZBTB6.p2:

Gene SymbolEntrez IDGene Name
ZBTB6 10773 zinc finger and BTB domain containing 6

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ZBTB6chr9_-_124715392-0.087.8e-01Click!


Activity profile for motif ZBTB6.p2.

activity profile for motif ZBTB6.p2


Sorted Z-values histogram for motif ZBTB6.p2

Sorted Z-values for motif ZBTB6.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZBTB6.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr22_-_37569962 2.137 NM_014293
 NPTXR
neuronal pentraxin receptor
chr2_-_233060774 2.039 NM_004826
 ECEL1
endothelin converting enzyme-like 1
chr14_+_28306633 1.888 FOXG1
forkhead box G1
chr8_+_104582151 1.785 NM_001100117
 RIMS2
regulating synaptic membrane exocytosis 2
chr10_-_99780574 1.644 NM_018058
 CRTAC1
cartilage acidic protein 1
chr8_-_21702273 1.543 NM_001165038
NM_001165039
NM_001495
 GFRA2


GDNF family receptor alpha 2


chr3_-_62835601 1.436


chr20_-_4177519 1.421 NM_000678
 ADRA1D
adrenergic, alpha-1D-, receptor
chr14_-_59407103 1.380 NM_021136
 RTN1
reticulon 1
chr15_+_39573363 1.250 NM_002220
 ITPKA
inositol 1,4,5-trisphosphate 3-kinase A
chr12_+_47975168 1.238 NM_006262
 PRPH
peripherin
chr13_-_24643620 1.125 FAM123A
family with sequence similarity 123A
chr2_-_217267742 1.082 IGFBP5
insulin-like growth factor binding protein 5
chr15_-_27650218 1.079 NM_015307
 FAM189A1
family with sequence similarity 189, member A1
chr22_-_37569679 1.071


chr3_-_159306532 1.057 NM_001163678
NM_003030
NM_006884
 SHOX2


short stature homeobox 2


chr14_+_58174489 1.034 NM_001079520
NM_016651
 DACT1

dapper, antagonist of beta-catenin, homolog 1 (Xenopus laevis)

chr3_-_171786468 1.000 NM_020949
 SLC7A14
solute carrier family 7 (cationic amino acid transporter, y+ system), member 14
chr10_+_24023680 0.987 NM_001098500
 KIAA1217
KIAA1217
chr5_-_134397740 0.984 NM_002653
 PITX1
paired-like homeodomain 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 41 entries
enrichment   p-value GO term description
3.50 3.11e-02 GO:0071804 cellular potassium ion transport
3.50 3.11e-02 GO:0071805 potassium ion transmembrane transport
1.73 2.17e-04 GO:0007409 axonogenesis
1.72 3.09e-08 GO:0030182 neuron differentiation
1.71 3.84e-05 GO:0031175 neuron projection development
1.71 1.94e-04 GO:0048812 neuron projection morphogenesis
1.71 3.20e-04 GO:0048667 cell morphogenesis involved in neuron differentiation
1.66 3.41e-05 GO:0048666 neuron development
1.66 2.72e-04 GO:0000904 cell morphogenesis involved in differentiation
1.65 4.44e-02 GO:0007411 axon guidance
1.63 9.09e-09 GO:0048468 cell development
1.63 6.64e-08 GO:0048699 generation of neurons
1.62 2.24e-08 GO:0022008 neurogenesis
1.62 1.27e-03 GO:0032990 cell part morphogenesis
1.62 1.42e-03 GO:0007417 central nervous system development
1.62 1.52e-03 GO:0048858 cell projection morphogenesis
1.61 2.21e-14 GO:0007399 nervous system development
1.57 4.51e-02 GO:0007268 synaptic transmission
1.56 1.90e-02 GO:0019226 transmission of nerve impulse
1.56 1.90e-02 GO:0035637 multicellular organismal signaling

Gene overrepresentation in compartment category:

Showing 1 to 10 of 10 entries
enrichment   p-value GO term description
3.80 1.70e-02 GO:0046658 anchored to plasma membrane
2.38 9.74e-03 GO:0033267 axon part
2.38 4.62e-02 GO:0030426 growth cone
2.19 3.45e-02 GO:0008021 synaptic vesicle
1.93 3.15e-02 GO:0034703 cation channel complex
1.82 1.24e-04 GO:0044456 synapse part
1.80 2.38e-06 GO:0045202 synapse
1.80 3.26e-02 GO:0030424 axon
1.64 8.56e-04 GO:0043005 neuron projection
1.21 3.25e-02 GO:0044459 plasma membrane part

Gene overrepresentation in function category:

Showing 1 to 14 of 14 entries
enrichment   p-value GO term description
2.07 1.10e-02 GO:0005267 potassium channel activity
1.86 1.11e-02 GO:0005244 voltage-gated ion channel activity
1.86 1.11e-02 GO:0022832 voltage-gated channel activity
1.67 2.81e-02 GO:0005261 cation channel activity
1.61 4.13e-02 GO:0022836 gated channel activity
1.54 4.05e-02 GO:0022838 substrate-specific channel activity
1.44 8.64e-03 GO:0043565 sequence-specific DNA binding
1.43 1.52e-04 GO:0001071 nucleic acid binding transcription factor activity
1.43 1.52e-04 GO:0003700 sequence-specific DNA binding transcription factor activity
1.41 5.86e-04 GO:0030528 transcription regulator activity
1.39 6.50e-03 GO:0022891 substrate-specific transmembrane transporter activity
1.34 4.00e-02 GO:0022857 transmembrane transporter activity
1.32 4.43e-02 GO:0022892 substrate-specific transporter activity
1.11 8.31e-03 GO:0005515 protein binding