Motif ID: ZEB1.p2

Z-value: 3.290


Transcription factors associated with ZEB1.p2:

Gene SymbolEntrez IDGene Name
ZEB1 6935 zinc finger E-box binding homeobox 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ZEB1chr10_+_31650069-0.504.7e-02Click!


Activity profile for motif ZEB1.p2.

activity profile for motif ZEB1.p2


Sorted Z-values histogram for motif ZEB1.p2

Sorted Z-values for motif ZEB1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZEB1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr19_+_6415259 9.760 NM_139161
NM_174881
 CRB3

crumbs homolog 3 (Drosophila)

chr22_+_38720881 9.737 NM_138435
 FAM83F
family with sequence similarity 83, member F
chr1_-_3556420 8.743 NM_017818
 WDR8
WD repeat domain 8
chr8_+_120289735 6.657 NM_052886
 MAL2
mal, T-cell differentiation protein 2 (gene/pseudogene)
chr7_-_22363036 5.608 NM_012294
 RAPGEF5
Rap guanine nucleotide exchange factor (GEF) 5
chr17_+_26839143 5.366 RAB11FIP4
RAB11 family interacting protein 4 (class II)
chr1_+_60053050 5.270 NM_015888
 HOOK1
hook homolog 1 (Drosophila)
chr2_-_73350103 5.095 NM_001080410
 FBXO41
F-box protein 41
chr1_+_1971762 5.011 NM_002744
 PRKCZ
protein kinase C, zeta
chr2_+_74595073 4.853 NM_016170
 TLX2
T-cell leukemia homeobox 2
chr3_-_42280442 4.364 NM_001174138
 CCK
cholecystokinin
chr11_+_45900731 3.899 GYLTL1B
glycosyltransferase-like 1B
chr4_-_5942818 3.898 CRMP1
collapsin response mediator protein 1
chr18_-_45975163 3.868 NM_001080467
 MYO5B
myosin VB
chr11_-_65895640 3.793 NM_001532
 SLC29A2
solute carrier family 29 (nucleoside transporters), member 2
chr19_+_40431618 3.729 LSR
lipolysis stimulated lipoprotein receptor
chr19_+_7566698 3.726 NM_001080429
NM_020902
 KIAA1543

KIAA1543

chr19_+_40431359 3.700 NM_015925
NM_205834
NM_205835
 LSR


lipolysis stimulated lipoprotein receptor


chr19_+_40431122 3.628 LSR
lipolysis stimulated lipoprotein receptor
chr21_-_38954433 3.614 ERG
v-ets erythroblastosis virus E26 oncogene homolog (avian)

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 27 entries
enrichment   p-value GO term description
3.65 7.71e-03 GO:0016338 calcium-independent cell-cell adhesion
1.58 4.30e-02 GO:0060284 regulation of cell development
1.42 5.95e-03 GO:0030182 neuron differentiation
1.38 4.05e-03 GO:0048699 generation of neurons
1.37 1.83e-06 GO:0007399 nervous system development
1.35 8.57e-03 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.35 1.84e-02 GO:0022008 neurogenesis
1.34 4.22e-04 GO:0051239 regulation of multicellular organismal process
1.33 3.81e-02 GO:0048468 cell development
1.33 4.44e-02 GO:0050793 regulation of developmental process
1.28 1.54e-03 GO:0023051 regulation of signaling
1.27 2.22e-02 GO:0009966 regulation of signal transduction
1.26 1.48e-03 GO:0048583 regulation of response to stimulus
1.25 4.09e-06 GO:0048518 positive regulation of biological process
1.24 1.55e-05 GO:0048731 system development
1.23 5.33e-06 GO:0048856 anatomical structure development
1.22 1.27e-03 GO:0048522 positive regulation of cellular process
1.22 2.42e-02 GO:0030154 cell differentiation
1.21 2.45e-05 GO:0007275 multicellular organismal development
1.21 4.14e-02 GO:0048869 cellular developmental process

Gene overrepresentation in compartment category:

Showing 1 to 10 of 10 entries
enrichment   p-value GO term description
1.66 2.72e-02 GO:0005911 cell-cell junction
1.52 1.67e-05 GO:0030054 cell junction
1.49 8.45e-03 GO:0043005 neuron projection
1.33 9.25e-03 GO:0005626 insoluble fraction
1.32 1.99e-02 GO:0005624 membrane fraction
1.30 4.76e-08 GO:0044459 plasma membrane part
1.29 7.28e-03 GO:0000267 cell fraction
1.12 2.72e-02 GO:0005886 plasma membrane
1.12 2.82e-02 GO:0071944 cell periphery
1.10 3.13e-05 GO:0005737 cytoplasm

Gene overrepresentation in function category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
1.45 2.50e-04 GO:0043565 sequence-specific DNA binding
1.10 2.18e-03 GO:0005515 protein binding