Motif ID: ZIC1..3.p2

Z-value: 2.829


Transcription factors associated with ZIC1..3.p2:

Gene SymbolEntrez IDGene Name
ZIC1 7545 Zic family member 1 (odd-paired homolog, Drosophila)
ZIC2 7546 Zic family member 2 (odd-paired homolog, Drosophila)
ZIC3 7547 Zic family member 3 (odd-paired homolog, Drosophila)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ZIC3chrX_+_1364763530.861.7e-05Click!
ZIC1chr3_+_1486105160.665.6e-03Click!
ZIC2chr13_+_994322580.665.8e-03Click!


Activity profile for motif ZIC1..3.p2.

activity profile for motif ZIC1..3.p2


Sorted Z-values histogram for motif ZIC1..3.p2

Sorted Z-values for motif ZIC1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZIC1..3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_+_28306633 5.997 FOXG1
forkhead box G1
chr4_-_174687104 4.636 HAND2
heart and neural crest derivatives expressed 2
chrX_-_107866262 4.462 NM_003604
IRS4
insulin receptor substrate 4
chr14_-_103058568 4.080 CKB
creatine kinase, brain
chr1_-_38285033 3.406 NM_002699
POU3F1
POU class 3 homeobox 1
chr4_-_174686918 3.214 HAND2
heart and neural crest derivatives expressed 2
chr11_-_75056761 3.011 MAP6
microtubule-associated protein 6
chr10_-_95350949 2.976 NM_006744
RBP4
retinol binding protein 4, plasma
chr12_-_42231990 2.870 NM_025003
ADAMTS20
ADAM metallopeptidase with thrombospondin type 1 motif, 20
chr13_-_52320774 2.750 NM_002590
NM_032949
PCDH8

protocadherin 8

chr16_-_47872880 2.737


chr9_+_99656013 2.692


chr19_+_10404110 2.589 NM_001111309
PDE4A
phosphodiesterase 4A, cAMP-specific
chr14_+_100362236 2.507 MEG3
maternally expressed 3 (non-protein coding)
chr8_+_1937711 2.504 KBTBD11
kelch repeat and BTB (POZ) domain containing 11
chr14_+_100362204 2.482 MEG3
maternally expressed 3 (non-protein coding)
chr14_-_103058865 2.478 NM_001823
CKB
creatine kinase, brain
chr11_-_75057062 2.475 NM_033063
NM_207577
MAP6

microtubule-associated protein 6

chr9_+_78824390 2.462 NM_001013735
FOXB2
forkhead box B2
chr3_-_73756668 2.334 NM_015009
PDZRN3
PDZ domain containing ring finger 3
chr16_-_47872973 2.331 CBLN1
cerebellin 1 precursor
chr17_-_72045218 2.297 NM_134268
CYGB
cytoglobin
chr2_+_219991342 2.260 NM_001927
DES
desmin
chr7_-_150737980 2.232 NM_198285
WDR86
WD repeat domain 86
chr20_+_36786540 2.174 SLC32A1
solute carrier family 32 (GABA vesicular transporter), member 1
chr2_+_137239583 2.173 THSD7B
thrombospondin, type I, domain containing 7B
chr7_-_27191287 2.146 NM_005523
HOXA11
homeobox A11
chr20_+_36786518 2.098 NM_080552
SLC32A1
solute carrier family 32 (GABA vesicular transporter), member 1
chr11_-_75057299 2.095 MAP6
microtubule-associated protein 6
chr17_-_25642962 2.069 NM_000386
BLMH
bleomycin hydrolase
chr8_+_31616809 2.014 NM_013962
NRG1
neuregulin 1
chr2_+_15999599 1.977 MYCN
v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
chr3_+_171619346 1.967 NM_005602
CLDN11
claudin 11
chrX_+_106057984 1.947 CLDN2
claudin 2
chr16_+_54247852 1.924 NM_001043
NM_001172504
SLC6A2

solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2

chr14_+_100263066 1.920 DLK1
delta-like 1 homolog (Drosophila)
chr3_-_130807865 1.911 NM_015103
PLXND1
plexin D1
chr19_-_51856129 1.897 NM_145056
DACT3
dapper, antagonist of beta-catenin, homolog 3 (Xenopus laevis)
chr6_-_85529884 1.884 TBX18
T-box 18
chr11_+_111288669 1.828 NM_001541
HSPB2-C11ORF52
HSPB2
HSPB2-C11orf52 read-through transcript
heat shock 27kDa protein 2
chr13_+_32488477 1.793 NM_004795
KL
klotho
chr9_-_72673753 1.779 NM_001007470
NM_020952
NM_024971
NM_206944
NM_206945
NM_206946
NM_206947
NM_206948
TRPM3







transient receptor potential cation channel, subfamily M, member 3







chr2_+_96355661 1.773 NM_178495
NM_001163524
ITPRIPL1

inositol 1,4,5-triphosphate receptor interacting protein-like 1

chrX_-_30237403 1.747 NM_000475
NR0B1
nuclear receptor subfamily 0, group B, member 1
chr15_+_58083798 1.733 FOXB1
forkhead box B1
chr5_-_132189762 1.728 NM_133456
SHROOM1
shroom family member 1
chr16_+_54247400 1.715 SLC6A2
solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
chr4_+_72271218 1.701 NM_001098484
NM_001134742
SLC4A4

solute carrier family 4, sodium bicarbonate cotransporter, member 4

chr12_+_56140184 1.691 NM_001160045
NM_001167609
NM_005269
GLI1


GLI family zinc finger 1


chr2_+_200031333 1.689


chr11_+_19691397 1.676 NM_145117
NM_182964
NAV2

neuron navigator 2

chr11_+_111288686 1.675 HSPB2-C11ORF52
HSPB2
HSPB2-C11orf52 read-through transcript
heat shock 27kDa protein 2
chrX_+_90576252 1.668 NM_080832
PABPC5
poly(A) binding protein, cytoplasmic 5
chr15_+_58083737 1.665


chr18_-_30057166 1.658 NOL4
nucleolar protein 4
chr22_-_36809094 1.656 NM_013356
SLC16A8
solute carrier family 16, member 8 (monocarboxylic acid transporter 3)
chr4_+_4912272 1.643 NM_002448
MSX1
msh homeobox 1
chr14_+_64077171 1.642 HSPA2
heat shock 70kDa protein 2
chr5_+_71438796 1.640 NM_005909
MAP1B
microtubule-associated protein 1B
chr5_-_577444 1.639 NM_004174
SLC9A3
solute carrier family 9 (sodium/hydrogen exchanger), member 3
chrX_+_72140076 1.630 NM_001042506
PABPC1L2B
poly(A) binding protein, cytoplasmic 1-like 2B
chrX_-_114374860 1.604 NM_020871
LRCH2
leucine-rich repeats and calponin homology (CH) domain containing 2
chr15_+_58083712 1.601 NM_012182
FOXB1
forkhead box B1
chr15_+_72208751 1.586 NM_001130136
ISLR2
immunoglobulin superfamily containing leucine-rich repeat 2
chr18_+_53170718 1.583 NM_015879
ST8SIA3
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr16_+_85158357 1.582 NM_005251
FOXC2
forkhead box C2 (MFH-1, mesenchyme forkhead 1)
chr10_-_99780574 1.581 NM_018058
CRTAC1
cartilage acidic protein 1
chrX_+_101792949 1.569 NM_001099410
NM_001099411
NM_014710
NM_001184727
GPRASP1



G protein-coupled receptor associated sorting protein 1



chr7_-_27180398 1.564 NM_018951
HOXA10
homeobox A10
chr8_+_19841209 1.563 LPL
lipoprotein lipase
chr6_-_33268177 1.561 NM_001163771
NM_080679
NM_080680
NM_080681
COL11A2



collagen, type XI, alpha 2



chr17_-_47592159 1.549 NM_001082533
CA10
carbonic anhydrase X
chr2_-_133144094 1.530 LYPD1
LY6/PLAUR domain containing 1
chr5_+_167889123 1.516


chr11_-_132318741 1.512 OPCML
opioid binding protein/cell adhesion molecule-like
chr10_-_62373828 1.508 NM_014836
RHOBTB1
Rho-related BTB domain containing 1
chr7_-_4867963 1.504 NM_020144
PAPOLB
poly(A) polymerase beta (testis specific)
chr9_-_138757175 1.491 NM_001001712
LCN10
lipocalin 10
chr12_-_3732478 1.486 EFCAB4B
EF-hand calcium binding domain 4B
chr3_+_49566901 1.482 NM_003458
BSN
bassoon (presynaptic cytomatrix protein)
chr17_+_56884560 1.482 TBX4
T-box 4
chr3_-_166397142 1.479 NM_014926
SLITRK3
SLIT and NTRK-like family, member 3
chr17_-_47592341 1.476 NM_001082534
CA10
carbonic anhydrase X
chr17_-_47591949 1.472 CA10
carbonic anhydrase X
chr9_-_121171400 1.467 NM_014618
DBC1
deleted in bladder cancer 1
chr2_+_176695658 1.457 NM_014213
HOXD9
homeobox D9
chr15_+_72209039 1.446 NM_001130137
ISLR2
immunoglobulin superfamily containing leucine-rich repeat 2
chr16_+_66244314 1.444 RLTPR
RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing
chr3_+_63238854 1.442 NM_001130003
SYNPR
synaptoporin
chr17_-_6887965 1.430 NM_153357
SLC16A11
solute carrier family 16, member 11 (monocarboxylic acid transporter 11)
chr14_+_28305922 1.424 NM_005249
FOXG1
forkhead box G1
chr1_-_39877883 1.422 HEYL
hairy/enhancer-of-split related with YRPW motif-like
chr2_+_15999396 1.415 MYCN
v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
chr3_+_134601479 1.413 NM_003571
BFSP2
beaded filament structural protein 2, phakinin
chr18_-_30057512 1.405 NM_001198546
NM_001198548
NM_003787
NOL4


nucleolar protein 4


chr21_+_33364420 1.403 OLIG1
oligodendrocyte transcription factor 1
chr1_+_11674365 1.403 NM_198545
C1orf187
chromosome 1 open reading frame 187
chr3_+_148610516 1.402 ZIC1
Zic family member 1 (odd-paired homolog, Drosophila)
chrX_-_24941098 1.395 ARX
aristaless related homeobox
chr3_+_185580554 1.388 NM_003741
CHRD
chordin
chr14_+_100270222 1.386 DLK1
delta-like 1 homolog (Drosophila)
chr22_-_43783449 1.383 PHF21B
PHD finger protein 21B
chrX_-_107221405 1.374 NM_002814
NM_170750
PSMD10

proteasome (prosome, macropain) 26S subunit, non-ATPase, 10

chrX_+_107221552 1.359 NM_052936
NM_178270
ATG4A

ATG4 autophagy related 4 homolog A (S. cerevisiae)

chr12_-_43556220 1.354 NELL2
NEL-like 2 (chicken)
chr19_-_13478037 1.354 NM_000068
NM_001127221
NM_001127222
NM_001174080
NM_023035
CACNA1A




calcium channel, voltage-dependent, P/Q type, alpha 1A subunit




chr1_-_39877928 1.342 NM_014571
HEYL
hairy/enhancer-of-split related with YRPW motif-like
chr17_-_47591691 1.334 CA10
carbonic anhydrase X
chr12_-_3732614 1.333 NM_001144958
NM_001144959
NM_032680
EFCAB4B


EF-hand calcium binding domain 4B


chr14_-_50631407 1.329 TRIM9
tripartite motif containing 9
chr17_+_56832492 1.325 TBX2
T-box 2
chr8_-_132122016 1.324 NM_001115
ADCY8
adenylate cyclase 8 (brain)
chr8_+_19841120 1.323 LPL
lipoprotein lipase
chr3_+_3816079 1.319 NM_020873
LRRN1
leucine rich repeat neuronal 1
chr19_+_19510098 1.311 CILP2
cartilage intermediate layer protein 2
chr1_-_29321599 1.308 NM_001171868
TMEM200B
transmembrane protein 200B
chr5_-_83715947 1.308 EDIL3
EGF-like repeats and discoidin I-like domains 3
chr1_-_90955365 1.293 NM_020063
BARHL2
BarH-like homeobox 2
chrX_+_101853912 1.288 NM_001004051
NM_001184874
NM_001184875
NM_001184876
NM_138437
GPRASP2




G protein-coupled receptor associated sorting protein 2




chr12_-_43556338 1.286 NELL2
NEL-like 2 (chicken)
chr13_-_24643620 1.279 FAM123A
family with sequence similarity 123A
chr6_+_101948102 1.278


chr4_+_156808261 1.258 NM_001130684
GUCY1A3
guanylate cyclase 1, soluble, alpha 3
chr2_-_144991386 1.253 ZEB2
zinc finger E-box binding homeobox 2
chr11_-_126375864 1.250 KIRREL3
kin of IRRE like 3 (Drosophila)
chr16_+_65840275 1.244 NM_004594
SLC9A5
solute carrier family 9 (sodium/hydrogen exchanger), member 5
chr12_+_79625538 1.244 NM_002469
MYF6
myogenic factor 6 (herculin)
chr17_+_70244945 1.241 NM_001006638
NM_001163990
RAB37

RAB37, member RAS oncogene family

chr22_-_42589543 1.236 NM_014351
SULT4A1
sulfotransferase family 4A, member 1
chr19_+_19510056 1.236 NM_153221
CILP2
cartilage intermediate layer protein 2
chr5_-_174803768 1.232 NM_000794
DRD1
dopamine receptor D1
chr15_+_39573363 1.225 NM_002220
ITPKA
inositol 1,4,5-trisphosphate 3-kinase A
chr20_-_22512893 1.218 FOXA2
forkhead box A2
chr11_+_122806196 1.214 LOC100128242
hypothetical LOC100128242
chrX_-_134013644 1.213 NM_001078172
NM_001134321
FAM127B

family with sequence similarity 127, member B

chr9_+_135389698 1.212 NM_014694
ADAMTSL2
ADAMTS-like 2
chr7_+_44110470 1.209 NM_001129
AEBP1
AE binding protein 1
chr11_-_67163600 1.196 NM_005995
TBX10
T-box 10
chr8_+_19841010 1.194 LPL
lipoprotein lipase
chr7_-_150306169 1.192 KCNH2
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr3_+_53504070 1.184 NM_000720
NM_001128839
NM_001128840
CACNA1D


calcium channel, voltage-dependent, L type, alpha 1D subunit


chr12_+_5411534 1.177 NM_001102654
NTF3
neurotrophin 3
chr6_+_72653126 1.171 RIMS1
regulating synaptic membrane exocytosis 1
chr2_+_74595073 1.169 NM_016170
TLX2
T-cell leukemia homeobox 2
chrX_-_20044670 1.166 NM_001168467
MAP7D2
MAP7 domain containing 2
chrX_-_53367246 1.160 NM_001111125
IQSEC2
IQ motif and Sec7 domain 2
chrX_-_13866565 1.158 NM_001001994
GPM6B
glycoprotein M6B
chr12_-_56312696 1.158 B4GALNT1
beta-1,4-N-acetyl-galactosaminyl transferase 1
chr2_-_74580173 1.157 LBX2
ladybird homeobox 2
chr11_-_32413486 1.153 WT1
Wilms tumor 1
chr22_-_17891777 1.151 CLDN5
claudin 5
chr5_-_44424423 1.140 NM_004465
FGF10
fibroblast growth factor 10
chr2_-_27339278 1.138 NM_003459
SLC30A3
solute carrier family 30 (zinc transporter), member 3
chr9_-_35948150 1.137 NM_019897
OR2S2
olfactory receptor, family 2, subfamily S, member 2
chr12_-_131256525 1.136 NM_021808
GALNT9
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 9 (GalNAc-T9)
chr19_-_11452439 1.135 NM_001420
NM_032281
ELAVL3

ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)

chr20_-_22514092 1.133 NM_153675
FOXA2
forkhead box A2
chr8_+_1909437 1.128 NM_014867
KBTBD11
kelch repeat and BTB (POZ) domain containing 11
chr16_+_1979959 1.126 NM_004209
SYNGR3
synaptogyrin 3
chr17_+_70244553 1.124 NM_001163989
RAB37
RAB37, member RAS oncogene family
chr11_+_67871999 1.124 LRP5
low density lipoprotein receptor-related protein 5
chr4_-_5940893 1.121 CRMP1
collapsin response mediator protein 1
chr3_+_112273464 1.119 NM_015480
PVRL3
poliovirus receptor-related 3
chr11_-_2115086 1.118 IGF2
insulin-like growth factor 2 (somatomedin A)
chr7_+_68702252 1.118 AUTS2
autism susceptibility candidate 2
chr16_-_265868 1.113 NM_003834
NM_183337
RGS11

regulator of G-protein signaling 11

chr17_+_42686217 1.111 ITGB3
integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
chr14_+_101097440 1.107 NM_001362
DIO3
deiodinase, iodothyronine, type III
chr21_+_33364316 1.104 NM_138983
OLIG1
oligodendrocyte transcription factor 1
chr20_-_1922393 1.102 NM_001190900
PDYN
prodynorphin
chr12_-_80676562 1.099 PPFIA2
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chr2_-_51112743 1.095 NRXN1
neurexin 1
chr6_+_99389318 1.095 POU3F2
POU class 3 homeobox 2
chr1_+_168899936 1.084 NM_006902
NM_022716
PRRX1

paired related homeobox 1

chr11_+_43920385 1.078 NM_001145033
C11orf96
chromosome 11 open reading frame 96
chr1_-_111018798 1.078 KCNA3
potassium voltage-gated channel, shaker-related subfamily, member 3
chr9_+_831689 1.077 NM_021951
DMRT1
doublesex and mab-3 related transcription factor 1
chr3_+_112273352 1.074 PVRL3
poliovirus receptor-related 3
chr11_-_289518 1.072 NM_001025295
IFITM5
interferon induced transmembrane protein 5
chrX_-_13866366 1.069


chr10_-_132999973 1.067 NM_174937
TCERG1L
transcription elongation regulator 1-like
chr13_-_24643778 1.066 NM_152704
NM_199138
FAM123A

family with sequence similarity 123A

chr7_+_44110527 1.064 AEBP1
AE binding protein 1
chr11_-_27697768 1.062 NM_001143807
BDNF
brain-derived neurotrophic factor
chr18_-_68685789 1.062 NM_138966
NETO1
neuropilin (NRP) and tolloid (TLL)-like 1
chr12_-_21985433 1.051 ABCC9
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr6_+_19946591 1.051


chr5_+_170779664 1.048 FGF18
fibroblast growth factor 18
chr16_+_30952382 1.048 NM_004604
STX4
syntaxin 4
chr9_+_130909926 1.046


chr6_-_166502119 1.043 NM_003181
T
T, brachyury homolog (mouse)
chr22_-_29231597 1.042 NM_001161368
NM_174977
SEC14L4

SEC14-like 4 (S. cerevisiae)

chr14_+_100262916 1.042 DLK1
delta-like 1 homolog (Drosophila)
chr9_-_103289154 1.042 NM_032342
C9orf125
chromosome 9 open reading frame 125
chr22_-_17892001 1.039 CLDN5
claudin 5
chr15_-_39593285 1.037 NM_001135685
NM_002344
NM_206961
LTK


leukocyte receptor tyrosine kinase


chr5_+_176170041 1.035 NM_133369
UNC5A
unc-5 homolog A (C. elegans)
chr2_-_192767844 1.032 NM_016192
TMEFF2
transmembrane protein with EGF-like and two follistatin-like domains 2
chr12_+_117903682 1.029 NM_194286
SRRM4
serine/arginine repetitive matrix 4
chr4_+_156807311 1.026 NM_000856
NM_001130682
NM_001130686
NM_001130687
NM_001130683
NM_001130685
GUCY1A3





guanylate cyclase 1, soluble, alpha 3






Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.39 1.42e-15 GO:0032502 developmental process
1.68 3.54e-15 GO:0007399 nervous system development
1.42 9.71e-15 GO:0048856 anatomical structure development
1.40 9.92e-15 GO:0007275 multicellular organismal development
1.45 2.81e-14 GO:0048731 system development
1.54 1.15e-13 GO:0030154 cell differentiation
1.52 2.63e-13 GO:0048869 cellular developmental process
1.79 1.36e-10 GO:0048699 generation of neurons
1.76 1.81e-10 GO:0022008 neurogenesis
1.85 1.06e-09 GO:0030182 neuron differentiation
1.25 1.81e-09 GO:0032501 multicellular organismal process
1.17 3.61e-08 GO:0065007 biological regulation
1.18 1.91e-07 GO:0050794 regulation of cellular process
1.17 5.18e-07 GO:0050789 regulation of biological process
1.63 7.31e-07 GO:0048468 cell development
1.47 8.49e-07 GO:0009653 anatomical structure morphogenesis
1.10 1.23e-06 GO:0009987 cellular process
1.77 6.45e-06 GO:0048666 neuron development
1.55 7.27e-05 GO:0050793 regulation of developmental process
1.29 1.02e-04 GO:0048518 positive regulation of biological process
1.63 1.41e-04 GO:0045595 regulation of cell differentiation
1.74 1.98e-04 GO:0031175 neuron projection development
1.35 2.83e-04 GO:0048513 organ development
1.71 4.44e-04 GO:0007417 central nervous system development
1.49 4.83e-04 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.77 4.92e-04 GO:0048667 cell morphogenesis involved in neuron differentiation
1.88 5.79e-04 GO:0007411 axon guidance
1.76 8.63e-04 GO:0007409 axonogenesis
1.28 9.98e-04 GO:0048522 positive regulation of cellular process
1.55 1.11e-03 GO:2000026 regulation of multicellular organismal development
1.22 1.28e-03 GO:0023052 signaling
1.69 1.30e-03 GO:0000904 cell morphogenesis involved in differentiation
1.57 1.47e-03 GO:0009790 embryo development
1.80 1.65e-03 GO:0007420 brain development
2.10 1.72e-03 GO:0045664 regulation of neuron differentiation
1.83 1.80e-03 GO:0007389 pattern specification process
1.45 1.92e-03 GO:0010646 regulation of cell communication
1.71 2.11e-03 GO:0048812 neuron projection morphogenesis
1.54 2.24e-03 GO:0010557 positive regulation of macromolecule biosynthetic process
1.49 2.69e-03 GO:0040011 locomotion
1.84 2.85e-03 GO:0001501 skeletal system development
1.39 4.40e-03 GO:0051239 regulation of multicellular organismal process
6.79 4.45e-03 GO:0042026 protein refolding
1.82 5.39e-03 GO:0060284 regulation of cell development
1.68 5.59e-03 GO:0051094 positive regulation of developmental process
1.79 6.45e-03 GO:0045597 positive regulation of cell differentiation
1.56 7.01e-03 GO:0030030 cell projection organization
1.21 8.20e-03 GO:0016043 cellular component organization
1.39 1.03e-02 GO:0010604 positive regulation of macromolecule metabolic process
1.47 1.04e-02 GO:0009891 positive regulation of biosynthetic process
1.47 1.12e-02 GO:0031328 positive regulation of cellular biosynthetic process
1.72 1.16e-02 GO:0009792 embryo development ending in birth or egg hatching
1.91 1.45e-02 GO:0003002 regionalization
1.72 1.50e-02 GO:0048598 embryonic morphogenesis
1.83 1.51e-02 GO:0051960 regulation of nervous system development
1.37 1.52e-02 GO:0009893 positive regulation of metabolic process
1.56 1.54e-02 GO:0000902 cell morphogenesis
1.79 1.71e-02 GO:0022603 regulation of anatomical structure morphogenesis
1.60 1.80e-02 GO:0032990 cell part morphogenesis
1.60 2.29e-02 GO:0048858 cell projection morphogenesis
1.37 2.66e-02 GO:0031325 positive regulation of cellular metabolic process
1.64 2.70e-02 GO:0032583 regulation of gene-specific transcription
1.20 2.90e-02 GO:0051179 localization
1.69 2.93e-02 GO:0043009 chordate embryonic development
1.47 3.22e-02 GO:0007267 cell-cell signaling
1.52 3.27e-02 GO:0032989 cellular component morphogenesis
1.84 4.09e-02 GO:0050767 regulation of neurogenesis
1.42 4.13e-02 GO:0006811 ion transport

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.33 1.15e-05 GO:0044459 plasma membrane part
2.26 8.14e-04 GO:0034703 cation channel complex
1.69 1.23e-03 GO:0045202 synapse
1.96 1.62e-03 GO:0034702 ion channel complex
1.17 4.38e-03 GO:0005886 plasma membrane
1.16 1.14e-02 GO:0071944 cell periphery
2.37 1.89e-02 GO:0008021 synaptic vesicle
1.75 2.49e-02 GO:0005667 transcription factor complex
1.69 2.51e-02 GO:0044456 synapse part

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.62 1.29e-08 GO:0001071 nucleic acid binding transcription factor activity
1.62 1.29e-08 GO:0003700 sequence-specific DNA binding transcription factor activity
1.77 1.32e-08 GO:0043565 sequence-specific DNA binding
1.14 1.71e-05 GO:0005515 protein binding
1.93 3.00e-04 GO:0005261 cation channel activity
1.62 3.11e-04 GO:0008324 cation transmembrane transporter activity
1.45 3.67e-04 GO:0030528 transcription regulator activity
2.21 1.82e-03 GO:0022843 voltage-gated cation channel activity
1.75 6.25e-03 GO:0022836 gated channel activity
1.70 1.63e-02 GO:0016563 transcription activator activity
1.58 1.76e-02 GO:0019904 protein domain specific binding
1.91 2.19e-02 GO:0005244 voltage-gated ion channel activity
1.91 2.19e-02 GO:0022832 voltage-gated channel activity
1.06 2.26e-02 GO:0005488 binding
1.43 3.05e-02 GO:0015075 ion transmembrane transporter activity
1.57 4.03e-02 GO:0015267 channel activity
1.57 4.39e-02 GO:0022803 passive transmembrane transporter activity
2.42 4.49e-02 GO:0005262 calcium channel activity
1.58 4.86e-02 GO:0005216 ion channel activity