Motif ID: ZNF423.p2

Z-value: 2.474


Transcription factors associated with ZNF423.p2:

Gene SymbolEntrez IDGene Name
ZNF423 23090 zinc finger protein 423

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ZNF423chr16_-_48418418-0.505.0e-02Click!


Activity profile for motif ZNF423.p2.

activity profile for motif ZNF423.p2


Sorted Z-values histogram for motif ZNF423.p2

Sorted Z-values for motif ZNF423.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZNF423.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_-_33178987 4.727 HNF1B
HNF1 homeobox B
chr5_+_170668892 4.372 NM_021025
TLX3
T-cell leukemia homeobox 3
chr20_-_21326046 4.110 NM_033176
NKX2-4
NK2 homeobox 4
chr7_-_19151509 3.499 NM_152898
FERD3L
Fer3-like (Drosophila)
chr12_+_109956210 3.336 NM_015267
CUX2
cut-like homeobox 2
chr15_-_81113676 3.039 NM_030594
CPEB1
cytoplasmic polyadenylation element binding protein 1
chr15_+_62230962 2.927 NM_024798
SNX22
sorting nexin 22
chr17_-_35017650 2.866 NEUROD2
neurogenic differentiation 2
chr19_+_19510056 2.799 NM_153221
CILP2
cartilage intermediate layer protein 2
chr19_+_14405100 2.784 NM_002741
PKN1
protein kinase N1
chr19_+_19510098 2.779 CILP2
cartilage intermediate layer protein 2
chr8_-_144313293 2.770 NM_001130478
LY6H
lymphocyte antigen 6 complex, locus H
chr17_-_35017691 2.582 NM_006160
NEUROD2
neurogenic differentiation 2
chr22_+_38183480 2.572 MGAT3
mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
chrX_-_48713194 2.530 NM_004979
KCND1
potassium voltage-gated channel, Shal-related subfamily, member 1
chr3_+_6877797 2.470 NM_000844
NM_181874
GRM7

glutamate receptor, metabotropic 7

chrX_+_136475979 2.462 NM_003413
ZIC3
Zic family member 3 (odd-paired homolog, Drosophila)
chr3_+_6877812 2.384 GRM7
glutamate receptor, metabotropic 7
chr10_-_120345148 2.347 NM_004248
PRLHR
prolactin releasing hormone receptor
chr19_-_55524445 2.314 NM_004977
KCNC3
potassium voltage-gated channel, Shaw-related subfamily, member 3
chrX_-_138114100 2.259 FGF13
fibroblast growth factor 13
chr8_-_133561738 2.244 KCNQ3
potassium voltage-gated channel, KQT-like subfamily, member 3
chr4_+_61749540 2.243 LPHN3
latrophilin 3
chr3_+_134947940 2.239 TF
transferrin
chrX_+_136476353 2.219 ZIC3
Zic family member 3 (odd-paired homolog, Drosophila)
chr8_-_133561933 2.207 KCNQ3
potassium voltage-gated channel, KQT-like subfamily, member 3
chrX_-_19050499 2.205 NM_001079858
NM_001079859
NM_001079860
NM_001184833
NM_001184834
NM_001184835
NM_001184836
NM_001184837
NM_005756
GPR64








G protein-coupled receptor 64








chr1_+_226261374 2.183 NM_033131
WNT3A
wingless-type MMTV integration site family, member 3A
chr12_-_42231990 2.173 NM_025003
ADAMTS20
ADAM metallopeptidase with thrombospondin type 1 motif, 20
chr5_-_1498510 2.168 NM_001044
SLC6A3
solute carrier family 6 (neurotransmitter transporter, dopamine), member 3
chr3_+_134947894 2.165 TF
transferrin
chr2_-_42574587 2.125 NM_133329
NM_172344
KCNG3

potassium voltage-gated channel, subfamily G, member 3

chr17_-_33179118 2.085 NM_000458
NM_001165923
HNF1B

HNF1 homeobox B

chr11_-_2248374 2.061 ASCL2
achaete-scute complex homolog 2 (Drosophila)
chr4_-_44145266 2.060 KCTD8
potassium channel tetramerisation domain containing 8
chr17_-_10042579 2.055 NM_201433
GAS7
growth arrest-specific 7
chr3_-_129694717 2.049 NM_032638
GATA2
GATA binding protein 2
chr5_+_68823874 2.043 NM_002538
OCLN
occludin
chr11_-_60819273 2.043 NM_152718
VWCE
von Willebrand factor C and EGF domains
chr13_-_50315832 2.013 NM_198989
DLEU7
deleted in lymphocytic leukemia, 7
chr15_-_93671314 1.988 LOC400456
hypothetical LOC400456
chrX_+_113724806 1.933 NM_000868
HTR2C
5-hydroxytryptamine (serotonin) receptor 2C
chr4_-_154929657 1.917 NM_003013
SFRP2
secreted frizzled-related protein 2
chr8_-_121892877 1.903 SNTB1
syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
chr10_-_118022965 1.890 NM_005264
GFRA1
GDNF family receptor alpha 1
chr1_-_23623713 1.865 NM_003196
TCEA3
transcription elongation factor A (SII), 3
chr20_+_22963949 1.852 NM_001052
SSTR4
somatostatin receptor 4
chr5_+_68824143 1.835 OCLN
occludin
chr11_+_17714070 1.826 NM_001112741
NM_004976
KCNC1

potassium voltage-gated channel, Shaw-related subfamily, member 1

chr4_-_20594645 1.790 KCNIP4
Kv channel interacting protein 4
chr16_+_170334 1.786 NM_005331
HBQ1
hemoglobin, theta 1
chr14_+_91859904 1.774 NM_153646
SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr6_+_168584678 1.771 NM_001166412
NM_022138
SMOC2

SPARC related modular calcium binding 2

chr19_-_3737279 1.759 MATK
megakaryocyte-associated tyrosine kinase
chr8_-_133562185 1.757 NM_004519
KCNQ3
potassium voltage-gated channel, KQT-like subfamily, member 3
chr22_+_38183262 1.709 NM_002409
MGAT3
mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
chr18_-_5533967 1.701 NM_012307
EPB41L3
erythrocyte membrane protein band 4.1-like 3
chr22_+_28446288 1.694 NM_182527
CABP7
calcium binding protein 7
chr1_-_210939820 1.694 BATF3
basic leucine zipper transcription factor, ATF-like 3
chr8_+_65656164 1.684 BHLHE22
basic helix-loop-helix family, member e22
chr19_-_11550765 1.668 NM_001111035
NM_001111036
ACP5

acid phosphatase 5, tartrate resistant

chr9_-_138234707 1.667 NM_014564
LHX3
LIM homeobox 3
chr6_+_168584722 1.654 SMOC2
SPARC related modular calcium binding 2
chr7_-_100091912 1.647 ACTL6B
actin-like 6B
chr7_-_100092003 1.643 NM_016188
ACTL6B
actin-like 6B
chr19_+_59158101 1.635 NM_031895
CACNG8
calcium channel, voltage-dependent, gamma subunit 8
chr19_+_14405216 1.616 PKN1
protein kinase N1
chr1_+_205885080 1.586 NM_175710
CR1L
complement component (3b/4b) receptor 1-like
chr22_-_42589543 1.582 NM_014351
SULT4A1
sulfotransferase family 4A, member 1
chr14_+_101097440 1.562 NM_001362
DIO3
deiodinase, iodothyronine, type III
chr10_+_3099708 1.545 NM_002627
PFKP
phosphofructokinase, platelet
chr9_-_90983195 1.535 SHC3
SHC (Src homology 2 domain containing) transforming protein 3
chr16_+_66236512 1.530 NM_001013838
RLTPR
RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing
chr3_+_138965844 1.529 SOX14
SRY (sex determining region Y)-box 14
chr13_+_95541093 1.528 NM_153456
HS6ST3
heparan sulfate 6-O-sulfotransferase 3
chr7_+_6622051 1.525 NM_017560
ZNF853
zinc finger protein 853
chr12_-_131415854 1.511 NM_001122636
GALNT9
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 9 (GalNAc-T9)
chr2_-_144991386 1.509 ZEB2
zinc finger E-box binding homeobox 2
chr11_+_92342436 1.508 NM_005959
MTNR1B
melatonin receptor 1B
chr3_-_129690056 1.498 NM_001145661
GATA2
GATA binding protein 2
chr6_+_168584706 1.497 SMOC2
SPARC related modular calcium binding 2
chrX_-_102205736 1.494 BEX1
brain expressed, X-linked 1
chr17_-_76754466 1.483 NM_001080395
AATK
apoptosis-associated tyrosine kinase
chr8_-_144313100 1.479 NM_001135655
LY6H
lymphocyte antigen 6 complex, locus H
chr12_+_63504618 1.472 NM_015279
TBC1D30
TBC1 domain family, member 30
chr1_-_40026718 1.461 BMP8B
bone morphogenetic protein 8b
chr5_-_45731976 1.457 NM_021072
HCN1
hyperpolarization activated cyclic nucleotide-gated potassium channel 1
chr19_+_52214885 1.441 NPAS1
neuronal PAS domain protein 1
chr5_+_32747194 1.435 NM_000908
NPR3
natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)
chr1_+_26609893 1.433 LIN28A
lin-28 homolog A (C. elegans)
chr12_+_63504708 1.429 TBC1D30
TBC1 domain family, member 30
chr5_-_45731588 1.423 HCN1
hyperpolarization activated cyclic nucleotide-gated potassium channel 1
chr20_-_25010756 1.414 NM_014588
NM_199425
VSX1

visual system homeobox 1

chr19_-_11452439 1.413 NM_001420
NM_032281
ELAVL3

ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)

chr10_-_118022707 1.408 NM_001145453
GFRA1
GDNF family receptor alpha 1
chr17_+_70244553 1.394 NM_001163989
RAB37
RAB37, member RAS oncogene family
chr14_-_76807302 1.386 NM_021257
NGB
neuroglobin
chr10_-_108914277 1.370 NM_001013031
NM_052918
SORCS1

sortilin-related VPS10 domain containing receptor 1

chr17_-_34014390 1.364 SRCIN1
SRC kinase signaling inhibitor 1
chr17_+_41432452 1.347 NM_001007532
STH
saitohin
chr9_-_16860719 1.329 NM_017637
BNC2
basonuclin 2
chrX_-_135941498 1.324 NM_054021
GPR101
G protein-coupled receptor 101
chr19_-_3737221 1.320 MATK
megakaryocyte-associated tyrosine kinase
chr19_+_53589943 1.317 NM_000836
GRIN2D
glutamate receptor, ionotropic, N-methyl D-aspartate 2D
chr9_+_139892049 1.314 NM_000718
CACNA1B
calcium channel, voltage-dependent, N type, alpha 1B subunit
chr11_+_76561471 1.297 MYO7A
myosin VIIA
chr18_+_75967902 1.296 NM_014913
ADNP2
ADNP homeobox 2
chr9_+_134027154 1.288 NM_032536
NTNG2
netrin G2
chr15_+_24662958 1.280 NM_000810
GABRA5
gamma-aminobutyric acid (GABA) A receptor, alpha 5
chrX_+_106050261 1.277 NM_020384
CLDN2
claudin 2
chr11_-_60819110 1.275 VWCE
von Willebrand factor C and EGF domains
chr18_+_74841262 1.272 NM_171999
SALL3
sal-like 3 (Drosophila)
chr19_-_11550576 1.271 NM_001111034
ACP5
acid phosphatase 5, tartrate resistant
chr15_-_75711743 1.271 NM_032808
LINGO1
leucine rich repeat and Ig domain containing 1
chr12_-_131256525 1.270 NM_021808
GALNT9
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 9 (GalNAc-T9)
chr17_+_70244945 1.256 NM_001006638
NM_001163990
RAB37

RAB37, member RAS oncogene family

chr10_-_95350949 1.254 NM_006744
RBP4
retinol binding protein 4, plasma
chr18_-_42590989 1.242 NM_013305
ST8SIA5
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
chrX_-_18282698 1.238 NM_006089
SCML2
sex comb on midleg-like 2 (Drosophila)
chr1_+_26609819 1.235 NM_024674
LIN28A
lin-28 homolog A (C. elegans)
chr21_+_25856311 1.234 MIR155HG
MIR155 host gene (non-protein coding)
chr8_-_144313053 1.228 LY6H
lymphocyte antigen 6 complex, locus H
chr9_-_37024358 1.225 NM_016734
PAX5
paired box 5
chrX_-_101297417 1.220 NM_001159560
NM_001012978
BEX5

brain expressed, X-linked 5

chr11_-_14621738 1.217 NM_148976
PSMA1
proteasome (prosome, macropain) subunit, alpha type, 1
chr8_+_121892719 1.212


chr15_+_24663199 1.204 NM_001165037
GABRA5
gamma-aminobutyric acid (GABA) A receptor, alpha 5
chr16_-_27982277 1.203 NM_001109763
GSG1L
GSG1-like
chr17_+_45993338 1.200 NM_018896
NM_198376
NM_198377
NM_198378
NM_198379
NM_198380
NM_198382
NM_198383
NM_198384
NM_198385
NM_198386
NM_198387
NM_198388
NM_198396
NM_198397
CACNA1G














calcium channel, voltage-dependent, T type, alpha 1G subunit














chr11_+_14621914 1.176 PDE3B
phosphodiesterase 3B, cGMP-inhibited
chr11_-_29995063 1.174 NM_002233
KCNA4
potassium voltage-gated channel, shaker-related subfamily, member 4
chr5_-_134397740 1.168 NM_002653
PITX1
paired-like homeodomain 1
chr12_-_48387394 1.159 FMNL3
formin-like 3
chr11_+_14621884 1.159 PDE3B
phosphodiesterase 3B, cGMP-inhibited
chr11_+_14621844 1.158 NM_000922
PDE3B
phosphodiesterase 3B, cGMP-inhibited
chr10_+_134823925 1.157 NM_152643
KNDC1
kinase non-catalytic C-lobe domain (KIND) containing 1
chr4_+_8633116 1.148 NM_080819
GPR78
G protein-coupled receptor 78
chr19_-_13478037 1.147 NM_000068
NM_001127221
NM_001127222
NM_001174080
NM_023035
CACNA1A




calcium channel, voltage-dependent, P/Q type, alpha 1A subunit




chr19_-_55763091 1.144 NM_001080457
LRRC4B
leucine rich repeat containing 4B
chr20_-_49592444 1.141 NFATC2
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
chr21_+_25933637 1.139 JAM2
junctional adhesion molecule 2
chr7_+_103756339 1.131 NM_199000
LHFPL3
lipoma HMGIC fusion partner-like 3
chr19_-_54005916 1.123 NM_001164773
NM_001190
BCAT2

branched chain amino-acid transaminase 2, mitochondrial

chr20_+_41978195 1.114 NM_001098796
NM_032883
TOX2

TOX high mobility group box family member 2

chr20_-_42872295 1.113 NM_182970
RIMS4
regulating synaptic membrane exocytosis 4
chr3_-_58538110 1.110 FAM107A
family with sequence similarity 107, member A
chr21_+_25933916 1.104 JAM2
junctional adhesion molecule 2
chr12_-_116021473 1.100 NM_001168325
NM_017899
TESC

tescalcin

chr16_+_53915971 1.099 NM_024335
IRX6
iroquois homeobox 6
chr16_-_2186465 1.098 NM_020764
CASKIN1
CASK interacting protein 1
chr17_+_73638430 1.098 NM_152468
TMC8
transmembrane channel-like 8
chr16_+_57055717 1.091 NDRG4
NDRG family member 4
chr3_+_185430910 1.090 NM_138345
VWA5B2
von Willebrand factor A domain containing 5B2
chr15_+_82113813 1.083 NM_207517
ADAMTSL3
ADAMTS-like 3
chr15_-_77169894 1.079 RASGRF1
Ras protein-specific guanine nucleotide-releasing factor 1
chr9_-_138236775 1.071 NM_178138
LHX3
LIM homeobox 3
chr16_-_87297525 1.065 NM_001171816
RNF166
ring finger protein 166
chr21_+_25933938 1.058 JAM2
junctional adhesion molecule 2
chr17_+_19377732 1.058 NM_018242
SLC47A1
solute carrier family 47, member 1
chr16_+_66236559 1.055 RLTPR
RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing
chr15_-_75711785 1.052 LINGO1
leucine rich repeat and Ig domain containing 1
chr6_+_111515341 1.052 SLC16A10
solute carrier family 16, member 10 (aromatic amino acid transporter)
chr11_-_132318080 1.041 NM_002545
OPCML
opioid binding protein/cell adhesion molecule-like
chr9_+_137107222 1.037 OLFM1
olfactomedin 1
chr6_+_39868126 1.035 DAAM2
dishevelled associated activator of morphogenesis 2
chr19_-_5291700 1.035 NM_002850
NM_130853
NM_130854
NM_130855
PTPRS



protein tyrosine phosphatase, receptor type, S



chrX_+_152562013 1.035 DUSP9
dual specificity phosphatase 9
chr1_-_210939929 1.032 NM_018664
BATF3
basic leucine zipper transcription factor, ATF-like 3
chr1_-_210939727 1.031


chr7_-_71439678 1.029 CALN1
calneuron 1
chr5_-_136862317 1.025 SPOCK1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
chr18_+_2896178 1.017 EMILIN2
elastin microfibril interfacer 2
chr12_-_48387233 1.014


chr15_+_77362200 1.006 NM_001146341
ANKRD34C
ankyrin repeat domain 34C
chr1_-_38285033 1.002 NM_002699
POU3F1
POU class 3 homeobox 1
chr5_-_136862786 0.997 NM_004598
SPOCK1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
chr6_+_39868116 0.995


chr10_+_135190855 0.992 NM_000773
CYP2E1
cytochrome P450, family 2, subfamily E, polypeptide 1
chr11_-_117173004 0.983 DSCAML1
Down syndrome cell adhesion molecule like 1
chr17_+_50698169 0.980 HLF
hepatic leukemia factor
chr21_+_45699830 0.976 NM_030582
NM_130444
COL18A1

collagen, type XVIII, alpha 1

chr19_-_3737382 0.973 NM_139354
NM_139355
MATK

megakaryocyte-associated tyrosine kinase

chr3_-_13436725 0.973 NUP210
nucleoporin 210kDa
chr3_+_37468542 0.971 NM_002207
ITGA9
integrin, alpha 9
chrX_+_30175191 0.970 NM_177404
MAGEB1
melanoma antigen family B, 1
chr14_+_103674812 0.961 NM_015656
KIF26A
kinesin family member 26A
chr12_-_63801539 0.947 WIF1
WNT inhibitory factor 1
chr4_-_46086528 0.946 NM_000807
GABRA2
gamma-aminobutyric acid (GABA) A receptor, alpha 2
chr12_-_48387459 0.940 NM_175736
NM_198900
FMNL3

formin-like 3

chr22_-_36153449 0.939 NM_052906
ELFN2
extracellular leucine-rich repeat and fibronectin type III domain containing 2
chr1_+_16247870 0.933 NM_001165945
CLCNKB
chloride channel Kb
chr3_-_124228999 0.931 SEMA5B
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B
chrX_+_152413646 0.929 BGN
biglycan
chrX_+_151975518 0.927 PNMA3
paraneoplastic antigen MA3
chr17_+_8865547 0.925 NM_004822
NTN1
netrin 1
chr7_-_156495985 0.919 NM_005515
MNX1
motor neuron and pancreas homeobox 1
chr3_+_123385870 0.915 NM_001178065
CASR
calcium-sensing receptor
chr5_+_175241449 0.908 CPLX2
complexin 2
chr18_+_11741470 0.906 NM_001142339
NM_002071
GNAL

guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type

chr16_-_3131348 0.903



Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.63 1.70e-07 GO:0007399 nervous system development
1.17 2.75e-04 GO:0065007 biological regulation
1.16 2.80e-03 GO:0050789 regulation of biological process
1.31 3.02e-03 GO:0048731 system development
1.26 4.21e-03 GO:0032502 developmental process
1.17 4.23e-03 GO:0050794 regulation of cellular process
1.29 4.95e-03 GO:0048856 anatomical structure development
1.35 1.82e-02 GO:0030154 cell differentiation
1.25 2.78e-02 GO:0007275 multicellular organismal development
1.33 3.39e-02 GO:0048869 cellular developmental process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
2.42 1.76e-02 GO:0031225 anchored to membrane
1.88 2.44e-02 GO:0044456 synapse part
1.11 3.34e-02 GO:0005737 cytoplasm
1.72 3.53e-02 GO:0045202 synapse
1.28 4.06e-02 GO:0044459 plasma membrane part

Nothing significant found in function category.