Motif ID: bHLH_family.p2

Z-value: 2.035


Transcription factors associated with bHLH_family.p2:

Gene SymbolEntrez IDGene Name
ARNTL 406 aryl hydrocarbon receptor nuclear translocator-like
ARNTL2 56938 aryl hydrocarbon receptor nuclear translocator-like 2
CLOCK 9575 clock homolog (mouse)
HES6 55502 hairy and enhancer of split 6 (Drosophila)
HEY1 23462 hairy/enhancer-of-split related with YRPW motif 1
HEY2 23493 hairy/enhancer-of-split related with YRPW motif 2
HEYL 26508 hairy/enhancer-of-split related with YRPW motif-like
ID1 3397 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
MITF 4286 microphthalmia-associated transcription factor
MLXIPL 51085 MLX interacting protein-like
MNT 4335 MAX binding protein
MXD3 83463 MAX dimerization protein 3
MXD4 10608 MAX dimerization protein 4
MXI1 4601 MAX interactor 1
NPAS2 4862 neuronal PAS domain protein 2
OLIG1 116448 oligodendrocyte transcription factor 1
OLIG2 10215 oligodendrocyte lineage transcription factor 2
TFE3 7030 transcription factor binding to IGHM enhancer 3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
OLIG1chr21_+_333643160.871.3e-05Click!
HEY2chr6_+_1261125880.731.4e-03Click!
ARNTL2chr12_+_27377034-0.721.6e-03Click!
MLXIPLchr7_-_726767500.711.9e-03Click!
MXD3chr5_-_1766718970.638.2e-03Click!
MXI1chr10_+_1119572920.591.7e-02Click!
HES6chr2_-_2388132840.458.2e-02Click!
HEYLchr1_-_39871226-0.391.4e-01Click!
TFE3chrX_-_48787876-0.371.5e-01Click!
ARNTLchr11_+_132559520.371.5e-01Click!
HEY1chr8_-_808424520.332.1e-01Click!
MNTchr17_-_22509670.253.5e-01Click!
OLIG2chr21_+_333200800.233.8e-01Click!
MITFchr3_+_70068440-0.204.6e-01Click!
MXD4chr4_-_22335040.136.4e-01Click!
CLOCKchr4_-_561077250.126.5e-01Click!
ID1chr20_+_296567440.116.9e-01Click!
NPAS2chr2_+_1008029230.077.9e-01Click!


Activity profile for motif bHLH_family.p2.

activity profile for motif bHLH_family.p2


Sorted Z-values histogram for motif bHLH_family.p2

Sorted Z-values for motif bHLH_family.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of bHLH_family.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr22_+_38720881 6.242 NM_138435
FAM83F
family with sequence similarity 83, member F
chr1_+_148521852 3.365 NM_144697
C1orf51
chromosome 1 open reading frame 51
chr8_+_120289735 3.328 NM_052886
MAL2
mal, T-cell differentiation protein 2 (gene/pseudogene)
chr15_-_81113676 3.275 NM_030594
CPEB1
cytoplasmic polyadenylation element binding protein 1
chr2_+_176680251 2.656 NM_021192
HOXD11
homeobox D11
chr13_+_32488477 2.606 NM_004795
KL
klotho
chrX_-_107866262 2.532 NM_003604
IRS4
insulin receptor substrate 4
chr2_+_74594093 2.520 TLX2
T-cell leukemia homeobox 2
chr5_+_132176921 2.501 NM_175873
ANKRD43
ankyrin repeat domain 43
chr1_+_237616457 2.447 CHRM3
cholinergic receptor, muscarinic 3
chr2_-_172675480 2.446 NM_004405
DLX2
distal-less homeobox 2
chr5_-_132976121 2.405 NM_015082
FSTL4
follistatin-like 4
chr17_-_37586716 2.321 NM_012285
KCNH4
potassium voltage-gated channel, subfamily H (eag-related), member 4
chr8_+_85258257 2.234 RALYL
RALY RNA binding protein-like
chr17_-_29930431 2.163 NM_207454
C17orf102
chromosome 17 open reading frame 102
chr1_-_92721633 2.117 GFI1
growth factor independent 1 transcription repressor
chrX_-_131919896 2.066 HS6ST2
heparan sulfate 6-O-sulfotransferase 2
chr11_+_45900731 2.023 GYLTL1B
glycosyltransferase-like 1B
chr11_-_61441536 2.017 NM_013401
RAB3IL1
RAB3A interacting protein (rabin3)-like 1
chr8_+_85258056 1.973 NM_173848
RALYL
RALY RNA binding protein-like
chr2_-_217267742 1.949 IGFBP5
insulin-like growth factor binding protein 5
chr2_-_172675873 1.943 DLX2
distal-less homeobox 2
chr1_-_92721943 1.938 NM_001127215
GFI1
growth factor independent 1 transcription repressor
chr5_+_89890366 1.883 NM_032119
GPR98
G protein-coupled receptor 98
chr8_+_85258007 1.870 NM_001100392
NM_001100393
RALYL

RALY RNA binding protein-like

chr1_-_92722088 1.851 GFI1
growth factor independent 1 transcription repressor
chr19_-_19599973 1.845 NM_004720
LPAR2
lysophosphatidic acid receptor 2
chr5_-_132976094 1.835 FSTL4
follistatin-like 4
chr10_+_22674379 1.821 NM_012443
NM_172242
SPAG6

sperm associated antigen 6

chr13_-_49597776 1.785 DLEU2
deleted in lymphocytic leukemia 2 (non-protein coding)
chr17_-_7138590 1.767 NM_015982
YBX2
Y box binding protein 2
chr4_+_54660954 1.749 NM_133267
GSX2
GS homeobox 2
chr1_+_26609893 1.728 LIN28A
lin-28 homolog A (C. elegans)
chr12_+_52713098 1.716 NM_018953
HOXC5
homeobox C5
chr17_-_7138535 1.713 YBX2
Y box binding protein 2
chr1_-_40555511 1.707 NM_001852
COL9A2
collagen, type IX, alpha 2
chr13_+_111769913 1.701 NM_005986
SOX1
SRY (sex determining region Y)-box 1
chr11_+_125279481 1.696 NM_013264
DDX25
DEAD (Asp-Glu-Ala-Asp) box polypeptide 25
chr1_-_40555413 1.675 COL9A2
collagen, type IX, alpha 2
chr3_-_172109119 1.655 NM_020390
EIF5A2
eukaryotic translation initiation factor 5A2
chr19_-_15204194 1.647 NM_024794
EPHX3
epoxide hydrolase 3
chr9_+_966963 1.629 NM_021240
DMRT3
doublesex and mab-3 related transcription factor 3
chr4_-_109307325 1.628 NM_001166119
LEF1
lymphoid enhancer-binding factor 1
chr19_+_54149941 1.615 BAX
BCL2-associated X protein
chr14_+_102458745 1.614 NM_030943
AMN
amnionless homolog (mouse)
chr17_-_42250961 1.581 NM_030753
WNT3
wingless-type MMTV integration site family, member 3
chr19_+_10392128 1.575 NM_001111307
PDE4A
phosphodiesterase 4A, cAMP-specific
chr19_-_19233370 1.567 HAPLN4
hyaluronan and proteoglycan link protein 4
chr8_-_75396016 1.556 NM_020647
JPH1
junctophilin 1
chr3_-_69064364 1.554 NM_001005527
NM_182522
FAM19A4

family with sequence similarity 19 (chemokine (C-C motif)-like), member A4

chr18_-_55091596 1.551 NM_013435
RAX
retina and anterior neural fold homeobox
chr1_+_208178160 1.542 NM_001146261
NM_001146262
NM_001146264
NM_153262
SYT14



synaptotagmin XIV



chr13_+_27392136 1.524 NM_000209
PDX1
pancreatic and duodenal homeobox 1
chr19_-_10625449 1.517 LOC147727
hypothetical LOC147727
chr3_+_148609841 1.514 NM_003412
ZIC1
Zic family member 1 (odd-paired homolog, Drosophila)
chr17_+_44429748 1.511 NM_001160423
NM_006546
IGF2BP1

insulin-like growth factor 2 mRNA binding protein 1

chr2_-_154043403 1.507 NM_019845
RPRM
reprimo, TP53 dependent G2 arrest mediator candidate
chr5_+_80292213 1.506 RASGRF2
Ras protein-specific guanine nucleotide-releasing factor 2
chr16_+_53522611 1.504 NM_005853
IRX5
iroquois homeobox 5
chr2_-_50428395 1.494 NM_138735
NRXN1
neurexin 1
chr7_-_72822471 1.489 NM_001306
CLDN3
claudin 3
chr1_+_26609819 1.488 NM_024674
LIN28A
lin-28 homolog A (C. elegans)
chr12_-_61615124 1.482 PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr8_-_121893468 1.470 NM_021021
SNTB1
syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
chr3_+_138965844 1.468 SOX14
SRY (sex determining region Y)-box 14
chr10_+_94823636 1.460 NM_000783
CYP26A1
cytochrome P450, family 26, subfamily A, polypeptide 1
chr14_-_46190690 1.457 NM_080746
RPL10L
ribosomal protein L10-like
chr19_+_54149963 1.455 BAX
BCL2-associated X protein
chr19_+_54149843 1.455 NM_004324
NM_138761
NM_138763
NM_138764
BAX



BCL2-associated X protein



chr3_-_71916877 1.431 NM_001126128
NM_021935
PROK2

prokineticin 2

chr3_-_172109075 1.420 EIF5A2
eukaryotic translation initiation factor 5A2
chr10_+_101079099 1.404 CNNM1
cyclin M1
chr8_+_21937533 1.392 NPM2
nucleophosmin/nucleoplasmin 2
chr9_+_70107602 1.391 NM_199135
FOXD4L3
FOXD4L6
forkhead box D4-like 3
forkhead box D4-like 6
chr12_+_48641545 1.382 NM_001651
AQP5
aquaporin 5
chr17_+_77925441 1.353 NM_018949
UTS2R
urotensin 2 receptor
chr2_+_26249463 1.349 NM_001168241
FAM59B
family with sequence similarity 59, member B
chr1_+_229365296 1.348 NM_001004342
TRIM67
tripartite motif containing 67
chr5_+_150807380 1.324 SLC36A1
solute carrier family 36 (proton/amino acid symporter), member 1
chr1_-_109458001 1.316 NM_001122961
C1orf194
chromosome 1 open reading frame 194
chr10_+_112826774 1.316 NM_000681
ADRA2A
adrenergic, alpha-2A-, receptor
chr3_+_23961739 1.312 NM_005126
NR1D2
nuclear receptor subfamily 1, group D, member 2
chr4_+_115739006 1.311 NM_001128174
UGT8
UDP glycosyltransferase 8
chr1_-_29321599 1.293 NM_001171868
TMEM200B
transmembrane protein 200B
chr3_+_127743868 1.290 CHST13
carbohydrate (chondroitin 4) sulfotransferase 13
chr12_-_56432385 1.286 NM_000075
CDK4
cyclin-dependent kinase 4
chr16_-_52876390 1.284 IRX3
iroquois homeobox 3
chr3_+_98016114 1.284 NM_001080448
EPHA6
EPH receptor A6
chr2_-_278181 1.284 NM_001002919
FAM150B
family with sequence similarity 150, member B
chr3_-_123995216 1.275 NM_024610
HSPBAP1
HSPB (heat shock 27kDa) associated protein 1
chr5_+_80292313 1.272 NM_006909
RASGRF2
Ras protein-specific guanine nucleotide-releasing factor 2
chr10_-_91285290 1.266 NM_213606
SLC16A12
solute carrier family 16, member 12 (monocarboxylic acid transporter 12)
chr1_+_177979113 1.264 FAM163A
family with sequence similarity 163, member A
chr12_-_61832856 1.263 NM_000706
AVPR1A
arginine vasopressin receptor 1A
chrX_+_117992603 1.254 LONRF3
LON peptidase N-terminal domain and ring finger 3
chr1_+_1971762 1.250 NM_002744
PRKCZ
protein kinase C, zeta
chr11_+_18300689 1.247 GTF2H1
general transcription factor IIH, polypeptide 1, 62kDa
chr1_+_20385164 1.245 NM_152376
UBXN10
UBX domain protein 10
chr3_+_139636104 1.244 NM_031913
ESYT3
extended synaptotagmin-like protein 3
chr17_-_7138620 1.235 YBX2
Y box binding protein 2
chr5_+_150807331 1.234 NM_078483
SLC36A1
solute carrier family 36 (proton/amino acid symporter), member 1
chr12_-_33483847 1.232 NM_198992
SYT10
synaptotagmin X
chr3_+_134239860 1.225 NM_001136469
NM_023943
TMEM108

transmembrane protein 108

chr4_-_15694407 1.222 PROM1
prominin 1
chr17_+_5913149 1.221 WSCD1
WSC domain containing 1
chr2_-_219633481 1.219 NM_002181
IHH
Indian hedgehog
chr9_+_128416542 1.209 NM_001174146
NM_001174147
NM_002316
LMX1B


LIM homeobox transcription factor 1, beta


chr11_+_7491789 1.208 PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr3_+_134239906 1.205 TMEM108
transmembrane protein 108
chr1_+_177979037 1.201 FAM163A
family with sequence similarity 163, member A
chr11_-_3620060 1.201 NM_053017
NM_001079536
ART5

ADP-ribosyltransferase 5

chr20_-_538909 1.199 NM_004609
TCF15
transcription factor 15 (basic helix-loop-helix)
chr13_-_19665036 1.183 GJB2
gap junction protein, beta 2, 26kDa
chrX_+_152562013 1.181 DUSP9
dual specificity phosphatase 9
chr19_+_10625896 1.181 NM_001137673
NM_004516
NM_012218
NM_017620
NM_153464
ILF3




interleukin enhancer binding factor 3, 90kDa




chr17_-_37828643 1.176 NM_012232
PTRF
polymerase I and transcript release factor
chr13_-_27572646 1.176 NM_004119
FLT3
fms-related tyrosine kinase 3
chr6_+_105511615 1.174 NM_001004317
LIN28B
lin-28 homolog B (C. elegans)
chr19_+_45799060 1.173 NM_001042545
LTBP4
latent transforming growth factor beta binding protein 4
chr8_+_98857190 1.165 LAPTM4B
lysosomal protein transmembrane 4 beta
chr4_+_164484540 1.161 NM_006174
NPY5R
neuropeptide Y receptor Y5
chr3_+_139636111 1.161 ESYT3
extended synaptotagmin-like protein 3
chr19_+_5632016 1.154 NM_198704
NM_198705
NM_198533
NM_198707
NM_198706
NM_198708
HSD11B1L





hydroxysteroid (11-beta) dehydrogenase 1-like





chr17_+_7225088 1.154 NM_003985
TNK1
tyrosine kinase, non-receptor, 1
chr1_+_222870573 1.152 CNIH3
cornichon homolog 3 (Drosophila)
chr11_+_32993973 1.144 NM_001077242
DEPDC7
DEP domain containing 7
chr20_-_3097070 1.142 NM_014731
ProSAPiP1
ProSAPiP1 protein
chr14_-_64416307 1.136 SPTB
spectrin, beta, erythrocytic
chr3_-_144164867 1.119 NM_198504
PAQR9
progestin and adipoQ receptor family member IX
chr9_-_108416 1.102 NM_207305
FOXD4
forkhead box D4
chr1_+_177978920 1.101 NM_173509
FAM163A
family with sequence similarity 163, member A
chr12_+_52618815 1.101 NM_017410
HOXC13
homeobox C13
chr4_-_15694691 1.099 NM_001145847
NM_001145848
PROM1

prominin 1

chr2_+_219991342 1.097 NM_001927
DES
desmin
chr5_-_172687798 1.093 STC2
stanniocalcin 2
chr2_+_113973130 1.088 NM_012184
FOXD4L1
forkhead box D4-like 1
chr14_-_64638974 1.085 NM_002382
NM_145112
NM_145113
NM_145114
NM_145116
NM_197957
MAX





MYC associated factor X





chr1_+_50286272 1.079 NM_001144777
ELAVL4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr12_-_56432375 1.077 CDK4
cyclin-dependent kinase 4
chr6_+_73388529 1.072 KCNQ5
potassium voltage-gated channel, KQT-like subfamily, member 5
chr8_-_109165012 1.071 NM_178565
RSPO2
R-spondin 2 homolog (Xenopus laevis)
chr9_+_37069882 1.069 LOC100506710
hypothetical LOC100506710
chr1_+_109458030 1.066 KIAA1324
KIAA1324
chr13_-_78075683 1.063 NM_006237
POU4F1
POU class 4 homeobox 1
chr10_+_94823221 1.063 NM_057157
CYP26A1
cytochrome P450, family 26, subfamily A, polypeptide 1
chr19_+_37528340 1.062 NM_001136156
NM_014910
ZNF507

zinc finger protein 507

chr1_+_109458093 1.061 NM_020775
KIAA1324
KIAA1324
chr14_-_63830830 1.061 NM_001040275
NM_001437
ESR2

estrogen receptor 2 (ER beta)

chr1_+_109458299 1.059 KIAA1324
KIAA1324
chr17_-_44058612 1.057 NM_024017
HOXB9
homeobox B9
chr1_-_111019148 1.057 NM_002232
KCNA3
potassium voltage-gated channel, shaker-related subfamily, member 3
chr7_-_124192265 1.055 GPR37
G protein-coupled receptor 37 (endothelin receptor type B-like)
chr1_-_21868380 1.054 NM_001145657
NM_002885
RAP1GAP

RAP1 GTPase activating protein

chr15_+_48261649 1.051 NM_001159629
NM_003645
SLC27A2

solute carrier family 27 (fatty acid transporter), member 2

chr3_-_171786468 1.050 NM_020949
SLC7A14
solute carrier family 7 (cationic amino acid transporter, y+ system), member 14
chr5_-_1348103 1.047 NM_001193376
NM_198253
TERT

telomerase reverse transcriptase

chr11_+_18300370 1.045 NM_001142307
NM_005316
GTF2H1

general transcription factor IIH, polypeptide 1, 62kDa

chrX_+_23262905 1.044 NM_173495
PTCHD1
patched domain containing 1
chrX_+_117992623 1.040 NM_001031855
NM_024778
LONRF3

LON peptidase N-terminal domain and ring finger 3

chr9_+_967386 1.038 DMRT3
doublesex and mab-3 related transcription factor 3
chr8_+_38950824 1.032 NM_153692
HTRA4
HtrA serine peptidase 4
chr4_-_13158391 1.030 LOC285548
hypothetical LOC285548
chr13_-_45640679 1.024 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr4_-_5942818 1.024 CRMP1
collapsin response mediator protein 1
chr5_+_150807397 1.018 SLC36A1
solute carrier family 36 (proton/amino acid symporter), member 1
chr22_-_49317408 1.017 ODF3B
outer dense fiber of sperm tails 3B
chr19_-_7845325 1.006 NM_001190467
FLJ22184
hypothetical protein FLJ22184
chr16_+_3002457 1.004 NM_020982
CLDN9
claudin 9
chr17_+_4434582 1.004 NM_001114974
SMTNL2
smoothelin-like 2
chr4_+_186176988 1.002 NM_001029887
HELT
HES/HEY-like transcription factor
chr10_+_101078784 0.995 NM_020348
CNNM1
cyclin M1
chr14_-_76807302 0.989 NM_021257
NGB
neuroglobin
chr19_-_9908014 0.987 NM_058164
OLFM2
olfactomedin 2
chr14_+_76634323 0.983 NM_033426
KIAA1737
KIAA1737
chr19_+_52215982 0.977 NM_002517
NPAS1
neuronal PAS domain protein 1
chr10_-_16604009 0.977 NM_001010908
C1QL3
complement component 1, q subcomponent-like 3
chr12_+_56299959 0.975 NM_133489
SLC26A10
solute carrier family 26, member 10
chr10_-_102978678 0.967 NM_006562
LBX1
ladybird homeobox 1
chr10_-_103991219 0.965 NM_005029
PITX3
paired-like homeodomain 3
chr3_-_126414252 0.965 NM_024628
SLC12A8
solute carrier family 12 (potassium/chloride transporters), member 8
chr14_+_51850754 0.962 NM_000956
PTGER2
prostaglandin E receptor 2 (subtype EP2), 53kDa
chr17_+_1120607 0.961 NM_001164405
BHLHA9
basic helix-loop-helix family, member a9
chr8_+_144428083 0.961 GLI4
GLI family zinc finger 4
chr11_-_66482366 0.957 NM_000920
NM_001040716
PC

pyruvate carboxylase

chr18_+_30810889 0.957 NM_001143826
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr1_+_175407153 0.953 NM_021165
FAM5B
family with sequence similarity 5, member B
chr8_-_17702991 0.953


chr12_-_61614930 0.951 NM_020700
PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr2_-_119322228 0.942 NM_001426
EN1
engrailed homeobox 1
chr17_-_34084682 0.941 NM_001130677
C17orf96
chromosome 17 open reading frame 96
chr2_+_5750229 0.932 NM_003108
SOX11
SRY (sex determining region Y)-box 11
chr7_-_82630063 0.932 NM_014510
NM_033026
PCLO

piccolo (presynaptic cytomatrix protein)

chr12_+_6514645 0.930 GAPDH
glyceraldehyde-3-phosphate dehydrogenase
chr16_-_65742323 0.928 NM_033309
B3GNT9
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9
chr12_-_56432377 0.920 CDK4
cyclin-dependent kinase 4
chr11_+_7491576 0.920 NM_003621
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr4_+_172971149 0.917 NM_001034845
GALNTL6
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 6
chr5_+_3649167 0.908 NM_024337
IRX1
iroquois homeobox 1
chr12_-_56432292 0.908 CDK4
cyclin-dependent kinase 4
chr14_-_90953883 0.907 NM_001080414
CCDC88C
coiled-coil domain containing 88C

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.11 2.73e-12 GO:0009987 cellular process
1.31 4.40e-10 GO:0048731 system development
1.28 1.62e-09 GO:0048856 anatomical structure development
1.43 3.02e-09 GO:0007399 nervous system development
1.26 5.77e-09 GO:0007275 multicellular organismal development
1.23 4.58e-08 GO:0032502 developmental process
1.32 8.71e-07 GO:0030154 cell differentiation
1.55 6.90e-06 GO:0010628 positive regulation of gene expression
1.29 9.08e-06 GO:0048869 cellular developmental process
1.30 1.84e-05 GO:0048513 organ development
1.11 9.59e-05 GO:0065007 biological regulation
1.45 1.19e-04 GO:0031328 positive regulation of cellular biosynthetic process
1.59 1.22e-04 GO:0007417 central nervous system development
1.60 1.55e-04 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.41 1.63e-04 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.52 2.07e-04 GO:0045893 positive regulation of transcription, DNA-dependent
1.11 3.64e-04 GO:0050789 regulation of biological process
1.22 3.74e-04 GO:0048518 positive regulation of biological process
1.42 4.49e-04 GO:0009891 positive regulation of biosynthetic process
1.48 5.29e-04 GO:0051254 positive regulation of RNA metabolic process
1.45 5.32e-04 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.44 6.42e-04 GO:0051173 positive regulation of nitrogen compound metabolic process
1.12 7.89e-04 GO:0050794 regulation of cellular process
1.25 1.01e-03 GO:0065008 regulation of biological quality
1.44 1.12e-03 GO:0010557 positive regulation of macromolecule biosynthetic process
1.22 1.96e-03 GO:0048522 positive regulation of cellular process
1.38 2.21e-03 GO:0022008 neurogenesis
1.32 3.28e-03 GO:0009893 positive regulation of metabolic process
1.38 6.45e-03 GO:0048699 generation of neurons
1.36 7.48e-03 GO:0048468 cell development
1.32 8.11e-03 GO:0010604 positive regulation of macromolecule metabolic process
1.59 8.65e-03 GO:0007420 brain development
1.53 9.56e-03 GO:0032583 regulation of gene-specific transcription
1.38 1.04e-02 GO:0055085 transmembrane transport
1.13 1.08e-02 GO:0032501 multicellular organismal process
1.43 1.50e-02 GO:0048878 chemical homeostasis
1.16 2.28e-02 GO:0051179 localization
1.56 2.38e-02 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
1.30 2.56e-02 GO:0031325 positive regulation of cellular metabolic process
1.14 3.83e-02 GO:0051716 cellular response to stimulus
1.28 4.07e-02 GO:0010033 response to organic substance

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.10 6.61e-05 GO:0005737 cytoplasm
1.06 4.93e-04 GO:0044424 intracellular part
1.06 6.61e-04 GO:0005622 intracellular
1.11 1.49e-03 GO:0044444 cytoplasmic part
1.07 4.22e-03 GO:0043226 organelle
1.37 4.80e-03 GO:0031988 membrane-bounded vesicle
1.11 5.99e-03 GO:0044422 organelle part
1.20 7.15e-03 GO:0044459 plasma membrane part
1.07 7.65e-03 GO:0043229 intracellular organelle
1.11 9.83e-03 GO:0044446 intracellular organelle part
1.34 1.05e-02 GO:0031982 vesicle
1.35 1.95e-02 GO:0016023 cytoplasmic membrane-bounded vesicle
1.33 2.48e-02 GO:0031410 cytoplasmic vesicle

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.62 4.17e-09 GO:0043565 sequence-specific DNA binding
1.42 5.82e-06 GO:0030528 transcription regulator activity
1.38 1.65e-04 GO:0001071 nucleic acid binding transcription factor activity
1.38 1.65e-04 GO:0003700 sequence-specific DNA binding transcription factor activity
1.11 1.88e-04 GO:0005515 protein binding
1.68 2.43e-04 GO:0016563 transcription activator activity
1.35 2.36e-03 GO:0022857 transmembrane transporter activity
1.40 7.44e-03 GO:0046983 protein dimerization activity
1.34 7.79e-03 GO:0022891 substrate-specific transmembrane transporter activity
1.05 8.95e-03 GO:0005488 binding
1.28 1.38e-02 GO:0005215 transporter activity
1.28 4.76e-02 GO:0022892 substrate-specific transporter activity