Motif ID: AIRE.p2

Z-value: 1.066


Transcription factors associated with AIRE.p2:

Gene SymbolEntrez IDGene Name
AIRE 326 autoimmune regulator

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
AIREchr21_+_445345750.273.1e-01Click!


Activity profile for motif AIRE.p2.

activity profile for motif AIRE.p2


Sorted Z-values histogram for motif AIRE.p2

Sorted Z-values for motif AIRE.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of AIRE.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr13_-_40454188 1.920 ELF1
E74-like factor 1 (ets domain transcription factor)
chr5_+_75734759 1.830 NM_006633
 IQGAP2
IQ motif containing GTPase activating protein 2
chr22_-_34886727 1.555 NM_145640
 APOL3
apolipoprotein L, 3
chr13_-_40454360 1.543 NM_001145353
 ELF1
E74-like factor 1 (ets domain transcription factor)
chr19_-_53444733 1.434 NM_001184901
NM_001184903
NM_014959
 CARD8


caspase recruitment domain family, member 8


chr16_+_20328355 1.300 NM_017888
 ACSM5
acyl-CoA synthetase medium-chain family member 5
chr4_+_69716298 1.235 NM_001075
NM_001144767
 UGT2B10

UDP glucuronosyltransferase 2 family, polypeptide B10

chr19_+_55627971 1.169 NM_004533
 MYBPC2
myosin binding protein C, fast type
chr11_-_73371531 1.128 NM_003355
 UCP2
uncoupling protein 2 (mitochondrial, proton carrier)
chr13_-_40491491 1.118 NM_172373
 ELF1
E74-like factor 1 (ets domain transcription factor)
chr19_+_18069596 1.104 NM_015016
 MAST3
microtubule associated serine/threonine kinase 3
chr4_-_139382672 1.016 NM_014331
 SLC7A11
solute carrier family 7, (cationic amino acid transporter, y+ system) member 11
chr16_-_3567354 1.008 NM_178844
 NLRC3
NLR family, CARD domain containing 3
chr7_-_149960612 0.863 NM_024711
 GIMAP6
GTPase, IMAP family member 6
chr19_-_6621078 0.858 TNFSF14
tumor necrosis factor (ligand) superfamily, member 14
chr2_-_190336168 0.852 NM_022353
 OSGEPL1
O-sialoglycoprotein endopeptidase-like 1
chr6_+_10629550 0.848 NM_145649
 GCNT2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr13_-_40491405 0.846 ELF1
E74-like factor 1 (ets domain transcription factor)
chr1_+_153222464 0.824 FLAD1
FAD1 flavin adenine dinucleotide synthetase homolog (S. cerevisiae)
chr19_-_44518516 0.817 NM_004877
 GMFG
glia maturation factor, gamma

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
2.04 7.24e-03 GO:0006952 defense response
2.03 4.93e-02 GO:0002682 regulation of immune system process

Nothing significant found in compartment category.

Nothing significant found in function category.