Motif ID: ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2

Z-value: 2.599


Transcription factors associated with ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2:

Gene SymbolEntrez IDGene Name
ARNT 405 aryl hydrocarbon receptor nuclear translocator
ARNT2 9915 aryl-hydrocarbon receptor nuclear translocator 2
BHLHB2 8553 basic helix-loop-helix domain containing, class B, 2
MAX 4149 MYC associated factor X
MYC 4609 v-myc myelocytomatosis viral oncogene homolog (avian)
USF1 7391 upstream transcription factor 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MYCchr8_+_128817494-0.665.0e-03Click!
BHLHE40chr3_+_4996305-0.552.6e-02Click!
USF1chr1_-_1592823760.421.1e-01Click!
ARNT2chr15_+_78483624-0.411.1e-01Click!
MAXchr14_-_64638974-0.312.5e-01Click!
ARNTchr1_-_149115835-0.273.1e-01Click!


Activity profile for motif ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2.

activity profile for motif ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2


Sorted Z-values histogram for motif ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2

Sorted Z-values for motif ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr17_-_53764867 9.225


chr12_-_56432292 8.512 CDK4
cyclin-dependent kinase 4
chr17_-_73636362 8.153 TMC6
transmembrane channel-like 6
chr12_-_56432377 7.453 CDK4
cyclin-dependent kinase 4
chr12_-_56432375 7.411 CDK4
cyclin-dependent kinase 4
chr12_-_56432385 6.824 NM_000075
 CDK4
cyclin-dependent kinase 4
chr1_+_20385164 6.803 NM_152376
 UBXN10
UBX domain protein 10
chr17_-_73636386 5.616 NM_001127198
 TMC6
transmembrane channel-like 6
chr11_-_61441536 5.241 NM_013401
 RAB3IL1
RAB3A interacting protein (rabin3)-like 1
chr8_+_142471290 5.023


chr7_+_101860958 4.258 NM_001126340
NM_032831
 ORAI2

ORAI calcium release-activated calcium modulator 2

chr17_+_73638430 4.199 NM_152468
 TMC8
transmembrane channel-like 8
chr1_-_152797820 4.183 UBE2Q1
ubiquitin-conjugating enzyme E2Q family member 1
chr6_-_43305156 4.139 NM_006443
NM_199184
 C6orf108

chromosome 6 open reading frame 108

chr16_-_1465021 4.122 CLCN7
chloride channel 7
chr7_+_101861007 3.886 ORAI2
ORAI calcium release-activated calcium modulator 2
chr16_-_1465007 3.811 CLCN7
chloride channel 7
chr11_-_71491983 3.744 LAMTOR1
late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
chr11_-_71491942 3.714 LAMTOR1
late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
chr17_-_44010543 3.492 NM_024015
 HOXB4
homeobox B4

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 28 entries
enrichment   p-value GO term description
2.83 3.76e-02 GO:0006839 mitochondrial transport
2.55 3.83e-02 GO:0009260 ribonucleotide biosynthetic process
2.34 3.12e-02 GO:0072522 purine-containing compound biosynthetic process
2.21 8.62e-03 GO:0034404 nucleobase, nucleoside and nucleotide biosynthetic process
2.21 8.62e-03 GO:0034654 nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process
2.17 4.26e-02 GO:0006732 coenzyme metabolic process
2.09 1.17e-02 GO:0051186 cofactor metabolic process
2.08 7.27e-03 GO:0018130 heterocycle biosynthetic process
1.88 4.16e-03 GO:0044271 cellular nitrogen compound biosynthetic process
1.73 8.03e-03 GO:0044283 small molecule biosynthetic process
1.65 2.21e-04 GO:0055085 transmembrane transport
1.47 4.53e-11 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.47 5.03e-08 GO:0090304 nucleic acid metabolic process
1.46 2.03e-05 GO:0016070 RNA metabolic process
1.45 2.29e-12 GO:0034641 cellular nitrogen compound metabolic process
1.45 1.36e-05 GO:0010467 gene expression
1.43 7.92e-12 GO:0006807 nitrogen compound metabolic process
1.42 3.17e-07 GO:0044249 cellular biosynthetic process
1.40 8.78e-07 GO:0009058 biosynthetic process
1.40 2.26e-03 GO:0034645 cellular macromolecule biosynthetic process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 37 entries
enrichment   p-value GO term description
5.52 3.93e-03 GO:0030530 heterogeneous nuclear ribonucleoprotein complex
2.45 4.33e-08 GO:0000323 lytic vacuole
2.45 4.33e-08 GO:0005764 lysosome
2.36 1.18e-08 GO:0005773 vacuole
2.31 3.55e-02 GO:0005765 lysosomal membrane
2.25 4.21e-03 GO:0044437 vacuolar part
2.21 1.16e-02 GO:0005774 vacuolar membrane
1.85 1.34e-05 GO:0030529 ribonucleoprotein complex
1.71 1.44e-03 GO:0005730 nucleolus
1.60 4.54e-02 GO:0005740 mitochondrial envelope
1.54 6.44e-03 GO:0031967 organelle envelope
1.52 7.70e-03 GO:0031975 envelope
1.52 1.62e-02 GO:0044429 mitochondrial part
1.48 5.11e-05 GO:0005654 nucleoplasm
1.47 4.60e-02 GO:0044451 nucleoplasm part
1.46 1.59e-09 GO:0031974 membrane-enclosed lumen
1.46 3.93e-09 GO:0070013 intracellular organelle lumen
1.45 1.38e-06 GO:0031981 nuclear lumen
1.44 1.36e-08 GO:0043233 organelle lumen
1.40 3.06e-06 GO:0044428 nuclear part

Gene overrepresentation in function category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
1.77 1.02e-07 GO:0003723 RNA binding
1.74 2.85e-02 GO:0022804 active transmembrane transporter activity
1.31 2.67e-02 GO:0016740 transferase activity
1.28 6.65e-03 GO:0000166 nucleotide binding
1.23 6.61e-03 GO:0003676 nucleic acid binding
1.17 3.24e-03 GO:0003824 catalytic activity
1.16 7.79e-05 GO:0005515 protein binding
1.07 1.03e-02 GO:0005488 binding