Motif ID: ATF5_CREB3.p2

Z-value: 4.250


Transcription factors associated with ATF5_CREB3.p2:

Gene SymbolEntrez IDGene Name
ATF5 22809 activating transcription factor 5
CREB3 10488 cAMP responsive element binding protein 3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ATF5chr19_+_55124211-0.862.2e-05Click!
CREB3chr9_+_357224900.263.2e-01Click!


Activity profile for motif ATF5_CREB3.p2.

activity profile for motif ATF5_CREB3.p2


Sorted Z-values histogram for motif ATF5_CREB3.p2

Sorted Z-values for motif ATF5_CREB3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ATF5_CREB3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_+_50663089 10.941 NM_001114171
NM_006732
FOSB

FBJ murine osteosarcoma viral oncogene homolog B

chr4_-_187884721 9.467


chr2_-_156897286 8.660 NM_006186
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr3_+_189354167 7.772 NM_001167672
LPP
LIM domain containing preferred translocation partner in lipoma
chr20_+_19863716 7.535 RIN2
Ras and Rab interactor 2
chr14_+_74815233 7.036 NM_005252
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr9_+_101623957 6.775 NM_006981
NM_173199
NR4A3

nuclear receptor subfamily 4, group A, member 3

chr2_-_216009015 6.399 NM_002026
NM_054034
NM_212474
NM_212476
NM_212478
NM_212482
FN1





fibronectin 1





chr11_+_12652427 6.260 NM_021961
TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr1_-_16355013 6.102 NM_004431
EPHA2
EPH receptor A2
chr10_+_102782151 5.936 SFXN3
sideroflexin 3
chr16_-_78192111 5.745 NM_001031804
NM_005360
MAF

v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)

chr18_+_44319365 5.722 NM_001142397
NM_014772
CTIF

CBP80/20-dependent translation initiation factor

chr8_+_94998258 5.588 NM_018444
NM_001161780
NM_001161779
NM_001161781
PDP1



pyruvate dehyrogenase phosphatase catalytic subunit 1



chr4_+_85723080 5.123 NM_001263
CDS1
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
chr4_+_75699652 4.887 NM_001657
AREG
amphiregulin
chr4_+_75529716 4.734 NM_001657
AREG
amphiregulin
chr5_-_57791544 4.589 NM_006622
PLK2
polo-like kinase 2
chr5_-_1935764 4.534 NM_016358
IRX4
iroquois homeobox 4
chr6_-_128883125 4.527 NM_002844
NM_001135648
PTPRK

protein tyrosine phosphatase, receptor type, K

chr20_+_19903778 4.477 RIN2
Ras and Rab interactor 2
chr1_-_208046011 4.348 NM_006147
IRF6
interferon regulatory factor 6
chr5_-_59100194 4.207 NM_001197218
PDE4D
phosphodiesterase 4D, cAMP-specific
chr12_-_121946581 4.147 VPS37B
vacuolar protein sorting 37 homolog B (S. cerevisiae)
chr3_-_189354510 4.135 LOC339929
hypothetical LOC339929
chr2_-_216008689 4.102 FN1
fibronectin 1
chr3_-_71196696 4.085 FOXP1
forkhead box P1
chr1_-_212791597 4.083 NM_005401
PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr1_+_85300580 4.082 NM_145172
WDR63
WD repeat domain 63
chrX_+_101910713 4.068 LOC100287765
hypothetical LOC100287765
chr1_-_212791467 4.025 PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr20_-_55718351 4.015 NM_020182
PMEPA1
prostate transmembrane protein, androgen induced 1
chr2_+_28469172 3.976 FOSL2
FOS-like antigen 2
chr4_-_88032570 3.955 NM_144645
C4orf36
chromosome 4 open reading frame 36
chr5_+_148186348 3.898 NM_000024
ADRB2
adrenergic, beta-2-, receptor, surface
chr12_+_12935619 3.892 GPRC5A
G protein-coupled receptor, family C, group 5, member A
chr12_+_12935222 3.888 NM_003979
GPRC5A
G protein-coupled receptor, family C, group 5, member A
chr4_+_152549776 3.873 NM_001109977
FAM160A1
family with sequence similarity 160, member A1
chr10_-_99436889 3.820 NM_021732
AVPI1
arginine vasopressin-induced 1
chr6_-_38715613 3.815 BTBD9
BTB (POZ) domain containing 9
chr21_+_32706615 3.802 NM_058187
C21orf63
chromosome 21 open reading frame 63
chr20_+_32610161 3.796 NM_032514
MAP1LC3A
microtubule-associated protein 1 light chain 3 alpha
chr1_-_184916044 3.737 NM_000963
PTGS2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
chr12_+_12935759 3.722 GPRC5A
G protein-coupled receptor, family C, group 5, member A
chr12_-_62902279 3.680 NM_152440
C12orf66
chromosome 12 open reading frame 66
chr6_-_38715901 3.680 NM_001099272
NM_052893
BTBD9

BTB (POZ) domain containing 9

chr12_-_113606322 3.633 NM_005996
NM_016569
TBX3

T-box 3

chr3_+_185538998 3.632 FAM131A
family with sequence similarity 131, member A
chr3_+_101462375 3.629 NM_018309
TBC1D23
TBC1 domain family, member 23
chr14_-_22458199 3.574 RBM23
RNA binding motif protein 23
chr13_-_20533703 3.547 NM_014572
LATS2
LATS, large tumor suppressor, homolog 2 (Drosophila)
chr14_-_22458134 3.527 RBM23
RNA binding motif protein 23
chr11_+_94141151 3.517 NM_130847
AMOTL1
angiomotin like 1
chr12_-_121946561 3.486


chr8_+_128875902 3.451 PVT1
Pvt1 oncogene (non-protein coding)
chrX_-_83644054 3.447 NM_001177478
NM_001177479
NM_144657
HDX


highly divergent homeobox


chr5_-_59100091 3.441 PDE4D
phosphodiesterase 4D, cAMP-specific
chr6_-_38715567 3.438 BTBD9
BTB (POZ) domain containing 9
chr7_-_27120015 3.417 HOXA3
homeobox A3
chr17_+_38831874 3.395 NM_001661
ARL4D
ADP-ribosylation factor-like 4D
chr7_+_28415495 3.386 LOC401317
hypothetical LOC401317
chr1_+_154297588 3.375 NM_020387
RAB25
RAB25, member RAS oncogene family
chr5_+_52812165 3.371 FST
follistatin
chr5_+_52812236 3.309 NM_006350
NM_013409
FST

follistatin

chr12_-_14847582 3.260 WBP11
WW domain binding protein 11
chr13_-_20533629 3.245 LATS2
LATS, large tumor suppressor, homolog 2 (Drosophila)
chr1_+_191044791 3.220 NM_002923
RGS2
regulator of G-protein signaling 2, 24kDa
chr12_-_121946635 3.215 NM_024667
VPS37B
vacuolar protein sorting 37 homolog B (S. cerevisiae)
chr10_+_102782156 3.205 SFXN3
sideroflexin 3
chr8_-_95343696 3.163 GEM
GTP binding protein overexpressed in skeletal muscle
chr6_+_30402986 3.162 NM_172016
TRIM39
tripartite motif containing 39
chr14_-_22458220 3.150 NM_001077351
NM_001077352
NM_018107
RBM23


RNA binding motif protein 23


chr5_-_58607673 3.098 NM_001197220
PDE4D
phosphodiesterase 4D, cAMP-specific
chr20_-_10602429 3.090 NM_000214
JAG1
jagged 1
chr17_+_8279860 3.082 NM_001025579
NM_030808
NDEL1

nudE nuclear distribution gene E homolog (A. nidulans)-like 1

chr3_-_64186151 3.076 NM_198859
PRICKLE2
prickle homolog 2 (Drosophila)
chr18_+_11841388 3.075 NM_020412
CHMP1B
chromatin modifying protein 1B
chrX_-_106846684 3.058 TSC22D3
TSC22 domain family, member 3
chr12_-_14847675 3.013 WBP11
WW domain binding protein 11
chr3_+_159771646 3.005 NM_001130156
NM_001130157
NM_001195432
NM_001195433
NM_001195434
NM_022443
MLF1





myeloid leukemia factor 1





chr10_-_90957028 3.004 NM_003956
CH25H
cholesterol 25-hydroxylase
chr12_-_14847634 2.977 NM_016312
WBP11
WW domain binding protein 11
chr2_+_28469199 2.974 FOSL2
FOS-like antigen 2
chr5_+_60663842 2.972 NM_020928
ZSWIM6
zinc finger, SWIM-type containing 6
chr13_+_72531098 2.952 NM_001730
KLF5
Kruppel-like factor 5 (intestinal)
chr8_-_95343716 2.942 NM_005261
NM_181702
GEM

GTP binding protein overexpressed in skeletal muscle

chr8_-_119192985 2.939 NM_000127
EXT1
exostosin 1
chr3_-_12775718 2.911 NM_018306
TMEM40
transmembrane protein 40
chr1_+_85819004 2.886 NM_001554
CYR61
cysteine-rich, angiogenic inducer, 61
chr1_+_19843261 2.870 NM_005380
NBL1
neuroblastoma, suppression of tumorigenicity 1
chr12_+_14847772 2.836 NM_175874
LOC100125871
C12orf60
hypothetical protein LOC100125871
chromosome 12 open reading frame 60
chr6_+_30402599 2.830 NM_021253
TRIM39
tripartite motif containing 39
chr3_-_53900888 2.817 NM_021237
SELK
selenoprotein K
chr9_-_98421894 2.809 NM_003671
NM_033331
CDC14B

CDC14 cell division cycle 14 homolog B (S. cerevisiae)

chr3_-_122951200 2.782 NM_004487
GOLGB1
golgin B1
chr21_-_42060266 2.770 NM_020639
RIPK4
receptor-interacting serine-threonine kinase 4
chr16_+_22733307 2.744 NM_006043
HS3ST2
heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr14_+_75521806 2.693 NM_001102564
NM_052873
C14orf179

chromosome 14 open reading frame 179

chr12_-_123568781 2.684


chr2_+_28469275 2.670 NM_005253
FOSL2
FOS-like antigen 2
chr14_+_67156405 2.653 ARG2
arginase, type II
chr4_+_52612197 2.653 NM_145263
SPATA18
spermatogenesis associated 18 homolog (rat)
chr20_+_51023159 2.653 TSHZ2
teashirt zinc finger homeobox 2
chr16_-_4528380 2.630 NM_001199054
C16orf5
chromosome 16 open reading frame 5
chr8_+_37672427 2.583 NM_025069
ZNF703
zinc finger protein 703
chr21_-_42060334 2.567 RIPK4
receptor-interacting serine-threonine kinase 4
chr8_-_48813256 2.553 NM_005195
CEBPD
CCAAT/enhancer binding protein (C/EBP), delta
chr20_+_55718619 2.550


chr14_+_67156386 2.543 ARG2
arginase, type II
chr10_+_103901922 2.516 NM_004741
NOLC1
nucleolar and coiled-body phosphoprotein 1
chr20_-_13567529 2.514 NM_017714
TASP1
taspase, threonine aspartase, 1
chr3_+_23962518 2.510 NM_001145425
NR1D2
nuclear receptor subfamily 1, group D, member 2
chr2_-_55090759 2.505 NM_007008
RTN4
reticulon 4
chr8_-_48813236 2.499 CEBPD
CCAAT/enhancer binding protein (C/EBP), delta
chr16_-_10581944 2.490 NM_001424
EMP2
epithelial membrane protein 2
chr17_+_2443652 2.489 NM_000430
PAFAH1B1
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
chr7_+_30140868 2.488 NM_152793
C7orf41
chromosome 7 open reading frame 41
chr12_+_970613 2.482 NM_178039
NM_178040
ERC1

ELKS/RAB6-interacting/CAST family member 1

chrX_+_100692071 2.473 NM_016608
ARMCX1
armadillo repeat containing, X-linked 1
chr12_+_109046522 2.473 NM_001143779
NM_014055
NM_031473
IFT81


intraflagellar transport 81 homolog (Chlamydomonas)


chr2_-_216944911 2.463 NM_020814
MARCH4
membrane-associated ring finger (C3HC4) 4
chr20_+_55718718 2.459


chr12_-_50871953 2.458 NM_001081492
NM_182507
KRT80

keratin 80

chr2_-_73193566 2.440 RAB11FIP5
RAB11 family interacting protein 5 (class I)
chr1_+_216585298 2.420 NM_001135599
NM_003238
TGFB2

transforming growth factor, beta 2

chr4_+_75393053 2.410 NM_001013442
EPGN
epithelial mitogen homolog (mouse)
chr4_-_119976736 2.395 NM_014822
SEC24D
SEC24 family, member D (S. cerevisiae)
chr3_-_109423858 2.395 NM_018010
IFT57
intraflagellar transport 57 homolog (Chlamydomonas)
chr12_+_55201854 2.395 NM_002898
RBMS2
RNA binding motif, single stranded interacting protein 2
chr9_-_14303509 2.394 NFIB
nuclear factor I/B
chr8_-_29263714 2.393 NM_001394
DUSP4
dual specificity phosphatase 4
chr4_-_119976631 2.371 SEC24D
SEC24 family, member D (S. cerevisiae)
chr7_-_36372971 2.369 NM_015314
KIAA0895
KIAA0895
chr14_+_67156323 2.346 NM_001172
ARG2
arginase, type II
chr5_+_56505412 2.341 NM_022913
GPBP1
GC-rich promoter binding protein 1
chr21_-_34820916 2.337 NM_203418
RCAN1
regulator of calcineurin 1
chr4_-_80079393 2.311 NM_001040202
PAQR3
progestin and adipoQ receptor family member III
chr7_-_129379947 2.307 NM_003344
NM_182697
UBE2H

ubiquitin-conjugating enzyme E2H (UBC8 homolog, yeast)

chr17_-_74348313 2.299 USP36
ubiquitin specific peptidase 36
chr7_+_22733290 2.279 NM_000600
IL6
interleukin 6 (interferon, beta 2)
chr7_-_106991941 2.259 NM_001161520
NM_006348
NM_181733
COG5


component of oligomeric golgi complex 5


chr18_+_7557313 2.250 NM_001105244
NM_002845
PTPRM

protein tyrosine phosphatase, receptor type, M

chr11_+_101291134 2.249 KIAA1377
KIAA1377
chr2_-_215711313 2.241 NM_173076
ABCA12
ATP-binding cassette, sub-family A (ABC1), member 12
chr11_+_110978309 2.240 NM_015191
SIK2
salt-inducible kinase 2
chr4_+_47181987 2.237 NM_020453
ATP10D
ATPase, class V, type 10D
chr6_+_116798791 2.235 NM_013352
DSE
dermatan sulfate epimerase
chr10_-_31360778 2.234 NM_001143766
NM_001143767
NM_001143768
NM_001143770
NM_001143771
NM_182755
ZNF438





zinc finger protein 438





chr8_+_38363150 2.228 NM_144652
LETM2
leucine zipper-EF-hand containing transmembrane protein 2
chrX_-_106846924 2.228 NM_004089
TSC22D3
TSC22 domain family, member 3
chr2_-_202354139 2.225 NM_001135745
NM_020919
ALS2

amyotrophic lateral sclerosis 2 (juvenile)

chr5_-_37875538 2.210 NM_000514
GDNF
glial cell derived neurotrophic factor
chr13_-_44461554 2.196 NM_012345
NUFIP1
nuclear fragile X mental retardation protein interacting protein 1
chr12_+_4300607 2.194 NM_020375
C12orf5
chromosome 12 open reading frame 5
chr6_+_89848229 2.180 PNRC1
proline-rich nuclear receptor coactivator 1
chr18_+_45342398 2.173 NM_006033
LIPG
lipase, endothelial
chr16_+_53522611 2.172 NM_005853
IRX5
iroquois homeobox 5
chr1_-_95165089 2.168 NM_001839
CNN3
calponin 3, acidic
chr1_+_156229934 2.166 KIRREL
kin of IRRE like (Drosophila)
chr3_+_186786655 2.165 NM_021627
SENP2
SUMO1/sentrin/SMT3 specific peptidase 2
chr3_-_59010740 2.158 NM_198463
C3orf67
chromosome 3 open reading frame 67
chr7_+_116447499 2.151 ST7
suppression of tumorigenicity 7
chr10_+_112247614 2.148 NM_004419
DUSP5
dual specificity phosphatase 5
chr7_-_121571472 2.142 NM_005763
AASS
aminoadipate-semialdehyde synthase
chr12_-_106011437 2.132 CRY1
cryptochrome 1 (photolyase-like)
chr7_+_143683365 2.126 NM_005435
ARHGEF5
Rho guanine nucleotide exchange factor (GEF) 5
chr1_-_8008934 2.120 ERRFI1
ERBB receptor feedback inhibitor 1
chr12_+_70519753 2.113 NM_001146213
NM_001146214
NM_022771
TBC1D15


TBC1 domain family, member 15


chr3_-_188945921 2.111 BCL6
B-cell CLL/lymphoma 6
chr7_+_27102508 2.103


chr1_+_156229686 2.088 NM_018240
KIRREL
kin of IRRE like (Drosophila)
chr13_-_79810972 2.086 SPRY2
sprouty homolog 2 (Drosophila)
chr3_-_59010797 2.074 C3orf67
chromosome 3 open reading frame 67
chr20_+_1254033 2.072 LOC100507495
hypothetical LOC100507495
chr16_+_20819488 2.072 NM_001128301
NM_001128302
LYRM1

LYR motif containing 1

chr5_+_102229612 2.072 PAM
peptidylglycine alpha-amidating monooxygenase
chr4_+_145786622 2.071 NM_022475
HHIP
hedgehog interacting protein
chr12_+_22669275 2.070 NM_001039481
NM_018638
ETNK1

ethanolamine kinase 1

chr12_+_22669352 2.065 ETNK1
ethanolamine kinase 1
chr9_+_111582317 2.062 NM_053016
NM_007203
NM_147150
PALM2
PALM2-AKAP2

paralemmin 2
PALM2-AKAP2 readthrough

chr20_-_42584006 2.061 SERINC3
serine incorporator 3
chr1_-_8008979 2.049 NM_018948
ERRFI1
ERBB receptor feedback inhibitor 1
chr2_-_222145240 2.049 NM_004438
EPHA4
EPH receptor A4
chr5_+_102229425 2.049 NM_000919
NM_001177306
NM_138766
NM_138821
NM_138822
PAM




peptidylglycine alpha-amidating monooxygenase




chr11_-_35503720 2.042 NM_001001991
NM_015430
PAMR1

peptidase domain containing associated with muscle regeneration 1

chr3_-_59010777 2.042 C3orf67
chromosome 3 open reading frame 67
chr7_-_143523582 2.040 NM_001003702
ARHGEF35
Rho guanine nucleotide exchange factor (GEF) 35
chr11_+_69165018 2.035 NM_053056
CCND1
cyclin D1
chrX_+_102498035 2.032 NM_001006612
NM_001006613
NM_001006614
NM_016303
WBP5



WW domain binding protein 5



chr1_-_95165037 2.026 CNN3
calponin 3, acidic
chr7_-_27108826 2.018 NM_006735
HOXA2
homeobox A2
chr16_+_85169615 2.017 NM_005250
FOXL1
forkhead box L1
chr9_-_101621964 2.014


chr22_+_29886224 2.009 RNF185
ring finger protein 185
chr8_-_18915443 2.006 NM_015310
PSD3
pleckstrin and Sec7 domain containing 3
chr17_-_8000362 2.001 PER1
period homolog 1 (Drosophila)
chr9_-_109291866 2.001 NM_004235
KLF4
Kruppel-like factor 4 (gut)
chr8_+_26296439 1.997 NM_004331
BNIP3L
BCL2/adenovirus E1B 19kDa interacting protein 3-like
chr6_+_139497933 1.980 NM_016217
HECA
headcase homolog (Drosophila)
chr6_-_18230829 1.970 NM_198586
NHLRC1
NHL repeat containing 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.39 5.78e-17 GO:0044260 cellular macromolecule metabolic process
1.32 1.27e-13 GO:0043170 macromolecule metabolic process
1.27 3.50e-13 GO:0044237 cellular metabolic process
1.44 1.04e-09 GO:0044267 cellular protein metabolic process
1.23 1.72e-09 GO:0044238 primary metabolic process
1.19 8.22e-08 GO:0008152 metabolic process
1.12 1.49e-07 GO:0009987 cellular process
1.48 6.61e-07 GO:0009059 macromolecule biosynthetic process
1.45 9.76e-07 GO:0010467 gene expression
1.55 1.23e-06 GO:0051641 cellular localization
1.47 1.55e-06 GO:0034645 cellular macromolecule biosynthetic process
1.66 3.91e-06 GO:0045184 establishment of protein localization
1.57 4.26e-06 GO:0051649 establishment of localization in cell
1.32 5.73e-06 GO:0019538 protein metabolic process
1.43 5.76e-06 GO:0006464 protein modification process
1.68 6.54e-06 GO:0046907 intracellular transport
1.65 7.71e-06 GO:0015031 protein transport
1.29 1.14e-05 GO:0060255 regulation of macromolecule metabolic process
1.28 1.25e-05 GO:0031323 regulation of cellular metabolic process
1.33 1.52e-05 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.56 1.61e-05 GO:0008104 protein localization
1.35 2.80e-05 GO:0048522 positive regulation of cellular process
1.49 3.77e-05 GO:0033036 macromolecule localization
1.36 3.89e-05 GO:0090304 nucleic acid metabolic process
1.26 9.51e-05 GO:0080090 regulation of primary metabolic process
1.28 1.13e-04 GO:0034641 cellular nitrogen compound metabolic process
1.38 1.30e-04 GO:0043412 macromolecule modification
1.40 1.50e-04 GO:0016070 RNA metabolic process
1.27 2.79e-04 GO:0006807 nitrogen compound metabolic process
1.29 5.27e-04 GO:0048518 positive regulation of biological process
1.23 7.37e-04 GO:0019222 regulation of metabolic process
1.31 7.42e-04 GO:0044249 cellular biosynthetic process
1.15 8.30e-04 GO:0050794 regulation of cellular process
1.28 1.27e-03 GO:0009889 regulation of biosynthetic process
1.71 1.47e-03 GO:0034613 cellular protein localization
1.28 1.67e-03 GO:0031326 regulation of cellular biosynthetic process
1.29 1.86e-03 GO:0009058 biosynthetic process
1.70 1.94e-03 GO:0070727 cellular macromolecule localization
1.29 2.28e-03 GO:0010556 regulation of macromolecule biosynthetic process
1.48 2.35e-03 GO:0032268 regulation of cellular protein metabolic process
1.30 2.35e-03 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.48 2.54e-03 GO:0007049 cell cycle
1.52 2.61e-03 GO:0006351 transcription, DNA-dependent
1.78 4.68e-03 GO:0006886 intracellular protein transport
1.47 5.75e-03 GO:0006793 phosphorus metabolic process
1.47 5.75e-03 GO:0006796 phosphate metabolic process
1.13 7.32e-03 GO:0050789 regulation of biological process
1.23 7.32e-03 GO:0071840 cellular component organization or biogenesis
1.44 7.51e-03 GO:0051246 regulation of protein metabolic process
1.27 1.23e-02 GO:0010468 regulation of gene expression
1.42 1.24e-02 GO:0010604 positive regulation of macromolecule metabolic process
1.46 1.25e-02 GO:0032774 RNA biosynthetic process
2.83 1.36e-02 GO:0002755 MyD88-dependent toll-like receptor signaling pathway
1.25 1.46e-02 GO:0071841 cellular component organization or biogenesis at cellular level
1.41 1.46e-02 GO:0044248 cellular catabolic process
1.22 1.49e-02 GO:0016043 cellular component organization
4.34 1.50e-02 GO:0000188 inactivation of MAPK activity
1.38 1.54e-02 GO:0035556 intracellular signal transduction
1.71 1.65e-02 GO:0007243 intracellular protein kinase cascade
1.71 1.65e-02 GO:0023014 signal transduction via phosphorylation event
1.60 1.73e-02 GO:0000278 mitotic cell cycle
2.86 1.87e-02 GO:0034130 toll-like receptor 1 signaling pathway
2.86 1.87e-02 GO:0034134 toll-like receptor 2 signaling pathway
1.52 1.92e-02 GO:0016192 vesicle-mediated transport
1.62 2.13e-02 GO:0044265 cellular macromolecule catabolic process
1.38 2.63e-02 GO:0009893 positive regulation of metabolic process
1.39 2.79e-02 GO:0031325 positive regulation of cellular metabolic process
1.24 3.54e-02 GO:0051171 regulation of nitrogen compound metabolic process
1.12 3.95e-02 GO:0065007 biological regulation
1.84 3.98e-02 GO:0010608 posttranscriptional regulation of gene expression
1.24 4.64e-02 GO:0071842 cellular component organization at cellular level
1.47 4.93e-02 GO:0022402 cell cycle process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.15 2.23e-18 GO:0005622 intracellular
1.16 7.82e-18 GO:0044424 intracellular part
1.20 6.58e-15 GO:0043227 membrane-bounded organelle
1.20 6.70e-15 GO:0043231 intracellular membrane-bounded organelle
1.17 3.39e-14 GO:0043229 intracellular organelle
1.17 4.50e-14 GO:0043226 organelle
1.26 6.97e-12 GO:0044422 organelle part
1.26 1.88e-11 GO:0044446 intracellular organelle part
1.18 2.60e-11 GO:0005737 cytoplasm
1.45 6.63e-10 GO:0044428 nuclear part
1.24 1.32e-09 GO:0005634 nucleus
1.46 3.49e-08 GO:0031981 nuclear lumen
1.37 5.83e-07 GO:0043233 organelle lumen
1.37 8.38e-07 GO:0070013 intracellular organelle lumen
1.19 9.57e-07 GO:0044444 cytoplasmic part
1.36 1.00e-06 GO:0031974 membrane-enclosed lumen
1.67 1.04e-05 GO:0015630 microtubule cytoskeleton
1.45 3.74e-05 GO:0005654 nucleoplasm
1.34 4.43e-05 GO:0005829 cytosol
1.27 5.25e-04 GO:0043228 non-membrane-bounded organelle
1.27 5.25e-04 GO:0043232 intracellular non-membrane-bounded organelle
1.23 2.78e-03 GO:0043234 protein complex
1.63 2.87e-03 GO:0005730 nucleolus
1.20 7.98e-03 GO:0032991 macromolecular complex
1.49 8.93e-03 GO:0044451 nucleoplasm part
1.72 1.08e-02 GO:0005815 microtubule organizing center
2.16 3.41e-02 GO:0016607 nuclear speck

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.24 6.05e-15 GO:0005515 protein binding
1.12 6.45e-11 GO:0005488 binding
1.41 1.32e-06 GO:0017076 purine nucleotide binding
1.41 1.40e-06 GO:0035639 purine ribonucleoside triphosphate binding
1.41 1.85e-06 GO:0032553 ribonucleotide binding
1.41 1.85e-06 GO:0032555 purine ribonucleotide binding
1.36 1.99e-06 GO:0000166 nucleotide binding
1.55 2.11e-04 GO:0003723 RNA binding
1.38 3.16e-04 GO:0030554 adenyl nucleotide binding
1.49 3.58e-04 GO:0001071 nucleic acid binding transcription factor activity
1.49 3.58e-04 GO:0003700 sequence-specific DNA binding transcription factor activity
1.38 4.80e-04 GO:0032559 adenyl ribonucleotide binding
1.38 5.38e-04 GO:0005524 ATP binding
1.23 1.66e-03 GO:0003676 nucleic acid binding
2.58 4.80e-03 GO:0017016 Ras GTPase binding
1.87 9.21e-03 GO:0003702 RNA polymerase II transcription factor activity
1.49 1.71e-02 GO:0043565 sequence-specific DNA binding
2.07 1.80e-02 GO:0004721 phosphoprotein phosphatase activity
1.83 2.41e-02 GO:0016791 phosphatase activity
2.33 3.36e-02 GO:0031267 small GTPase binding
1.44 3.47e-02 GO:0016462 pyrophosphatase activity
1.38 3.77e-02 GO:0030528 transcription regulator activity
1.43 4.12e-02 GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
1.43 4.89e-02 GO:0016817 hydrolase activity, acting on acid anhydrides