Motif ID: ATF6.p2

Z-value: 2.544


Transcription factors associated with ATF6.p2:

Gene SymbolEntrez IDGene Name
ATF6 22926 activating transcription factor 6

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ATF6chr1_+_160002733-0.621.1e-02Click!


Activity profile for motif ATF6.p2.

activity profile for motif ATF6.p2


Sorted Z-values histogram for motif ATF6.p2

Sorted Z-values for motif ATF6.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ATF6.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr13_-_20533629 4.934 LATS2
LATS, large tumor suppressor, homolog 2 (Drosophila)
chr19_+_54723044 3.882 RCN3
reticulocalbin 3, EF-hand calcium binding domain
chr2_+_28469275 3.843 NM_005253
FOSL2
FOS-like antigen 2
chr7_+_27191534 3.755 HOXA11-AS1
HOXA11 antisense RNA 1 (non-protein coding)
chr2_+_28469199 3.642 FOSL2
FOS-like antigen 2
chr2_+_28469172 3.389 FOSL2
FOS-like antigen 2
chr16_-_71639670 3.034 NM_006885
ZFHX3
zinc finger homeobox 3
chr8_+_26296439 2.921 NM_004331
BNIP3L
BCL2/adenovirus E1B 19kDa interacting protein 3-like
chr13_-_35818777 2.911 NM_001142295
SPG20
spastic paraplegia 20 (Troyer syndrome)
chr4_-_186693574 2.844 NM_001114107
NM_014476
PDLIM3

PDZ and LIM domain 3

chr10_-_62373828 2.740 NM_014836
RHOBTB1
Rho-related BTB domain containing 1
chr13_-_35818603 2.687 NM_001142296
NM_015087
SPG20

spastic paraplegia 20 (Troyer syndrome)

chr9_+_35528890 2.680 RUSC2
RUN and SH3 domain containing 2
chr6_+_144649142 2.674 UTRN
utrophin
chr17_-_13445942 2.617 NM_006042
HS3ST3A1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
chr13_-_20533703 2.584 NM_014572
LATS2
LATS, large tumor suppressor, homolog 2 (Drosophila)
chrX_+_100692071 2.578 NM_016608
ARMCX1
armadillo repeat containing, X-linked 1
chr9_+_35896188 2.524 NM_001039792
HRCT1
histidine rich carboxyl terminus 1
chr7_-_27191287 2.503 NM_005523
HOXA11
homeobox A11
chr13_-_35818491 2.475 SPG20
spastic paraplegia 20 (Troyer syndrome)

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 48 entries
enrichment   p-value GO term description
8.71 1.51e-05 GO:0048199 vesicle targeting, to, from or within Golgi
6.34 2.85e-04 GO:0006903 vesicle targeting
5.94 2.11e-02 GO:0006901 vesicle coating
5.70 3.10e-02 GO:0006900 membrane budding
4.90 2.72e-03 GO:0051650 establishment of vesicle localization
3.89 4.66e-02 GO:0051648 vesicle localization
3.12 4.77e-04 GO:0048193 Golgi vesicle transport
2.03 2.63e-04 GO:0070727 cellular macromolecule localization
2.01 4.79e-04 GO:0034613 cellular protein localization
1.96 3.27e-02 GO:0006886 intracellular protein transport
1.92 1.73e-06 GO:0015031 protein transport
1.91 2.06e-06 GO:0045184 establishment of protein localization
1.85 3.53e-07 GO:0008104 protein localization
1.83 2.68e-02 GO:0010942 positive regulation of cell death
1.76 2.39e-07 GO:0033036 macromolecule localization
1.75 7.00e-04 GO:0006351 transcription, DNA-dependent
1.73 4.01e-03 GO:0046907 intracellular transport
1.70 1.79e-02 GO:0016192 vesicle-mediated transport
1.66 6.18e-05 GO:0051641 cellular localization
1.61 1.51e-02 GO:0032774 RNA biosynthetic process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 23 entries
enrichment   p-value GO term description
6.79 4.77e-02 GO:0030663 COPI coated vesicle membrane
4.06 4.58e-02 GO:0030120 vesicle coat
1.84 5.96e-03 GO:0000139 Golgi membrane
1.76 4.27e-03 GO:0044431 Golgi apparatus part
1.62 8.52e-04 GO:0005794 Golgi apparatus
1.59 2.69e-02 GO:0031410 cytoplasmic vesicle
1.58 2.55e-02 GO:0031982 vesicle
1.56 2.47e-03 GO:0005783 endoplasmic reticulum
1.47 1.12e-03 GO:0012505 endomembrane system
1.44 9.63e-05 GO:0031090 organelle membrane
1.37 2.14e-02 GO:0031981 nuclear lumen
1.36 5.31e-03 GO:0044428 nuclear part
1.28 2.73e-07 GO:0044446 intracellular organelle part
1.28 2.82e-07 GO:0044422 organelle part
1.25 3.50e-05 GO:0005634 nucleus
1.24 9.69e-06 GO:0044444 cytoplasmic part
1.23 1.33e-11 GO:0043227 membrane-bounded organelle
1.23 1.64e-11 GO:0043231 intracellular membrane-bounded organelle
1.19 1.31e-09 GO:0043226 organelle
1.19 1.32e-09 GO:0043229 intracellular organelle

Gene overrepresentation in function category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
2.00 3.45e-02 GO:0005083 small GTPase regulator activity
1.69 8.46e-05 GO:0001071 nucleic acid binding transcription factor activity
1.69 8.46e-05 GO:0003700 sequence-specific DNA binding transcription factor activity
1.68 1.13e-04 GO:0030528 transcription regulator activity
1.66 1.62e-02 GO:0043565 sequence-specific DNA binding
1.31 4.13e-02 GO:0003677 DNA binding
1.23 3.56e-07 GO:0005515 protein binding
1.11 2.16e-04 GO:0005488 binding