Motif ID: ATF6.p2

Z-value: 2.544


Transcription factors associated with ATF6.p2:

Gene SymbolEntrez IDGene Name
ATF6 22926 activating transcription factor 6

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ATF6chr1_+_160002733-0.621.1e-02Click!


Activity profile for motif ATF6.p2.

activity profile for motif ATF6.p2


Sorted Z-values histogram for motif ATF6.p2

Sorted Z-values for motif ATF6.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ATF6.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr13_-_20533629 4.934 LATS2
LATS, large tumor suppressor, homolog 2 (Drosophila)
chr19_+_54723044 3.882 RCN3
reticulocalbin 3, EF-hand calcium binding domain
chr2_+_28469275 3.843 NM_005253
FOSL2
FOS-like antigen 2
chr7_+_27191534 3.755 HOXA11-AS1
HOXA11 antisense RNA 1 (non-protein coding)
chr2_+_28469199 3.642 FOSL2
FOS-like antigen 2
chr2_+_28469172 3.389 FOSL2
FOS-like antigen 2
chr16_-_71639670 3.034 NM_006885
ZFHX3
zinc finger homeobox 3
chr8_+_26296439 2.921 NM_004331
BNIP3L
BCL2/adenovirus E1B 19kDa interacting protein 3-like
chr13_-_35818777 2.911 NM_001142295
SPG20
spastic paraplegia 20 (Troyer syndrome)
chr4_-_186693574 2.844 NM_001114107
NM_014476
PDLIM3

PDZ and LIM domain 3

chr10_-_62373828 2.740 NM_014836
RHOBTB1
Rho-related BTB domain containing 1
chr13_-_35818603 2.687 NM_001142296
NM_015087
SPG20

spastic paraplegia 20 (Troyer syndrome)

chr9_+_35528890 2.680 RUSC2
RUN and SH3 domain containing 2
chr6_+_144649142 2.674 UTRN
utrophin
chr17_-_13445942 2.617 NM_006042
HS3ST3A1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
chr13_-_20533703 2.584 NM_014572
LATS2
LATS, large tumor suppressor, homolog 2 (Drosophila)
chrX_+_100692071 2.578 NM_016608
ARMCX1
armadillo repeat containing, X-linked 1
chr9_+_35896188 2.524 NM_001039792
HRCT1
histidine rich carboxyl terminus 1
chr7_-_27191287 2.503 NM_005523
HOXA11
homeobox A11
chr13_-_35818491 2.475 SPG20
spastic paraplegia 20 (Troyer syndrome)
chr17_-_44043361 2.445 NM_004502
HOXB7
homeobox B7
chr9_+_35528628 2.422 NM_001135999
RUSC2
RUN and SH3 domain containing 2
chr12_-_123568781 2.402


chr13_-_35818396 2.350 SPG20
spastic paraplegia 20 (Troyer syndrome)
chr3_-_73756668 2.347 NM_015009
PDZRN3
PDZ domain containing ring finger 3
chr3_+_44878380 2.286 NM_144638
TMEM42
transmembrane protein 42
chr17_-_44043278 2.278 HOXB7
homeobox B7
chr8_-_38245694 2.273 NM_001102559
NM_001102560
NM_032483
PPAPDC1B


phosphatidic acid phosphatase type 2 domain containing 1B


chr16_+_415606 2.247 RAB11FIP3
RAB11 family interacting protein 3 (class II)
chr8_+_106400322 2.202 NM_012082
ZFPM2
zinc finger protein, multitype 2
chr11_+_119701047 2.185 NM_001198670
NM_001198671
NM_001198672
NM_001198673
NM_001198674
NM_001198675
NM_174926
TMEM136






transmembrane protein 136






chr16_-_65742323 2.117 NM_033309
B3GNT9
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9
chr6_-_128883125 2.073 NM_002844
NM_001135648
PTPRK

protein tyrosine phosphatase, receptor type, K

chr5_-_172130766 2.060 NM_004417
DUSP1
dual specificity phosphatase 1
chr12_+_54396099 2.046 BLOC1S1-RDH5
BLOC1S1
BLOC1S1-RDH5 read-through transcript
biogenesis of lysosomal organelles complex-1, subunit 1
chr8_-_82186832 2.033 NM_018440
PAG1
phosphoprotein associated with glycosphingolipid microdomains 1
chr1_+_220857774 2.003 NM_198551
MIA3
melanoma inhibitory activity family, member 3
chr1_+_110328850 1.985 AHCYL1
adenosylhomocysteinase-like 1
chrX_-_34585287 1.975 NM_031442
TMEM47
transmembrane protein 47
chr3_+_150330060 1.963 NM_032383
HPS3
Hermansky-Pudlak syndrome 3
chr12_+_54396118 1.927 BLOC1S1
biogenesis of lysosomal organelles complex-1, subunit 1
chr5_+_102229425 1.925 NM_000919
NM_001177306
NM_138766
NM_138821
NM_138822
PAM




peptidylglycine alpha-amidating monooxygenase




chr12_+_54396086 1.890 NM_001487
BLOC1S1
biogenesis of lysosomal organelles complex-1, subunit 1
chr1_+_110328922 1.888 AHCYL1
adenosylhomocysteinase-like 1
chr15_-_38000379 1.878 NM_007223
GPR176
G protein-coupled receptor 176
chr10_+_102749597 1.851 LZTS2
leucine zipper, putative tumor suppressor 2
chr7_-_6490375 1.846 KDELR2
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
chr9_+_101623957 1.842 NM_006981
NM_173199
NR4A3

nuclear receptor subfamily 4, group A, member 3

chr12_-_105165805 1.837 NM_006825
CKAP4
cytoskeleton-associated protein 4
chr7_-_6490214 1.835 NM_001100603
NM_006854
KDELR2

KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2

chr7_+_93861808 1.830 NM_000089
COL1A2
collagen, type I, alpha 2
chr4_-_187884721 1.821


chr3_-_131312963 1.779


chr15_-_80125514 1.777 MEX3B
mex-3 homolog B (C. elegans)
chr15_-_80125403 1.777 NM_032246
MEX3B
mex-3 homolog B (C. elegans)
chr7_+_28415495 1.773 LOC401317
hypothetical LOC401317
chr7_-_19123787 1.764 NM_000474
TWIST1
twist homolog 1 (Drosophila)
chr18_+_7557313 1.742 NM_001105244
NM_002845
PTPRM

protein tyrosine phosphatase, receptor type, M

chr7_+_128257698 1.737 NM_001127487
NM_001458
FLNC

filamin C, gamma

chr14_+_22375753 1.735 MMP14
matrix metallopeptidase 14 (membrane-inserted)
chr7_-_19123765 1.726 TWIST1
twist homolog 1 (Drosophila)
chr16_+_55580910 1.724 NM_032206
NLRC5
NLR family, CARD domain containing 5
chr5_+_102229612 1.704 PAM
peptidylglycine alpha-amidating monooxygenase
chr5_+_149845503 1.701 NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr3_-_75566781 1.688 FAM86DP
family with sequence similarity 86, member D, pseudogene
chr15_-_99609197 1.687 CHSY1
chondroitin sulfate synthase 1
chr3_+_173240126 1.667 FNDC3B
fibronectin type III domain containing 3B
chr20_+_32610161 1.658 NM_032514
MAP1LC3A
microtubule-associated protein 1 light chain 3 alpha
chr9_-_72218098 1.653 KLF9
Kruppel-like factor 9
chr1_-_206484258 1.633 NM_025179
PLXNA2
plexin A2
chr3_-_8518327 1.623 LOC100288428
hypothetical LOC100288428
chr4_-_141293572 1.622 MAML3
mastermind-like 3 (Drosophila)
chr14_+_22375632 1.606 NM_004995
MMP14
matrix metallopeptidase 14 (membrane-inserted)
chr6_-_127822227 1.585 NM_014702
KIAA0408
KIAA0408
chr14_+_22375747 1.575 MMP14
matrix metallopeptidase 14 (membrane-inserted)
chr1_+_110328830 1.571 NM_006621
AHCYL1
adenosylhomocysteinase-like 1
chr11_+_119701214 1.571 TMEM136
transmembrane protein 136
chr17_+_56884560 1.569 TBX4
T-box 4
chr16_+_66855827 1.558 NM_001076785
NM_003983
SLC7A6

solute carrier family 7 (cationic amino acid transporter, y+ system), member 6

chr17_-_44042924 1.548 HOXB7
homeobox B7
chr4_-_111763655 1.541 NM_000325
PITX2
paired-like homeodomain 2
chr3_-_131313010 1.537


chr4_-_111763356 1.531 PITX2
paired-like homeodomain 2
chr15_-_53668341 1.531 NM_015617
PYGO1
pygopus homolog 1 (Drosophila)
chr14_+_22375656 1.526 MMP14
matrix metallopeptidase 14 (membrane-inserted)
chr20_-_39379533 1.520 ZHX3
zinc fingers and homeoboxes 3
chr10_+_112247614 1.517 NM_004419
DUSP5
dual specificity phosphatase 5
chr3_+_173240107 1.511 NM_022763
FNDC3B
fibronectin type III domain containing 3B
chr16_-_78192111 1.505 NM_001031804
NM_005360
MAF

v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)

chr20_+_32755778 1.503 NM_021202
TP53INP2
tumor protein p53 inducible nuclear protein 2
chr1_+_110328941 1.497 AHCYL1
adenosylhomocysteinase-like 1
chr14_+_58174489 1.486 NM_001079520
NM_016651
DACT1

dapper, antagonist of beta-catenin, homolog 1 (Xenopus laevis)

chr6_+_151602787 1.479 NM_005100
AKAP12
A kinase (PRKA) anchor protein 12
chr5_+_60663842 1.457 NM_020928
ZSWIM6
zinc finger, SWIM-type containing 6
chr17_-_37828643 1.456 NM_012232
PTRF
polymerase I and transcript release factor
chr12_-_113328271 1.453 NM_181486
TBX5
T-box 5
chr8_+_133856738 1.450 NM_016018
NM_032205
NM_198513
PHF20L1


PHD finger protein 20-like 1


chr5_+_170221584 1.444 NM_022897
RANBP17
RAN binding protein 17
chr11_+_69165119 1.443 CCND1
cyclin D1
chr8_+_22479115 1.427 NM_001018003
SORBS3
sorbin and SH3 domain containing 3
chr8_+_37672427 1.427 NM_025069
ZNF703
zinc finger protein 703
chr10_-_118022965 1.425 NM_005264
GFRA1
GDNF family receptor alpha 1
chr22_-_29833484 1.412 NM_080430
SELM
selenoprotein M
chr5_-_99898788 1.399


chr6_-_75972473 1.397 COL12A1
collagen, type XII, alpha 1
chr3_+_127118130 1.394 LOC100125556
family with sequence similarity 86, member A pseudogene
chr15_+_76952356 1.394 MORF4L1
mortality factor 4 like 1
chr14_+_100362204 1.394 MEG3
maternally expressed 3 (non-protein coding)
chr20_+_43895802 1.374 NM_001042632
NM_001042633
NM_033421
NM_152897
SNX21



sorting nexin family member 21



chrX_+_102749489 1.373 NM_001006933
NM_032926
TCEAL3

transcription elongation factor A (SII)-like 3

chr16_-_4837266 1.372 NM_032569
GLYR1
glyoxylate reductase 1 homolog (Arabidopsis)
chr2_-_236741352 1.329 NM_001485
GBX2
gastrulation brain homeobox 2
chr8_+_133856793 1.326 PHF20L1
PHD finger protein 20-like 1
chr11_+_69165065 1.317 CCND1
cyclin D1
chr2_-_216008689 1.317 FN1
fibronectin 1
chr15_-_99609648 1.313 NM_014918
CHSY1
chondroitin sulfate synthase 1
chr21_-_37366684 1.309 NM_153681
PIGP
phosphatidylinositol glycan anchor biosynthesis, class P
chr2_-_216009015 1.303 NM_002026
NM_054034
NM_212474
NM_212476
NM_212478
NM_212482
FN1





fibronectin 1





chr3_+_150191884 1.280 NM_001184720
NM_001184721
NM_004130
GYG1


glycogenin 1


chr21_-_37367259 1.278 NM_153682
PIGP
phosphatidylinositol glycan anchor biosynthesis, class P
chr11_+_117948350 1.273 ARCN1
archain 1
chr16_-_69277355 1.269 NM_138383
MTSS1L
metastasis suppressor 1-like
chr9_-_35062643 1.267 NM_007126
VCP
valosin containing protein
chr11_+_117948301 1.265 NM_001142281
NM_001655
ARCN1

archain 1

chr3_+_173240136 1.260 FNDC3B
fibronectin type III domain containing 3B
chr1_-_143750988 1.259 NM_001198832
PDE4DIP
phosphodiesterase 4D interacting protein
chr10_-_14090459 1.239 FRMD4A
FERM domain containing 4A
chr6_+_158990982 1.233 NM_001009991
SYTL3
synaptotagmin-like 3
chr11_+_32068990 1.232 NM_002901
RCN1
reticulocalbin 1, EF-hand calcium binding domain
chr2_+_190916571 1.231 INPP1
inositol polyphosphate-1-phosphatase
chr11_+_69165018 1.226 NM_053056
CCND1
cyclin D1
chr3_-_39124124 1.224 NM_031899
GORASP1
golgi reassembly stacking protein 1, 65kDa
chr3_-_49370682 1.218 GPX1
glutathione peroxidase 1
chr14_+_23905984 1.215 NM_001136022
NM_001198967
NFATC4

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4

chr9_-_35062545 1.212 VCP
valosin containing protein
chr3_-_109423858 1.207 NM_018010
IFT57
intraflagellar transport 57 homolog (Chlamydomonas)
chr19_-_18493886 1.207 NM_006532
ELL
elongation factor RNA polymerase II
chr12_+_58276114 1.196 SLC16A7
solute carrier family 16, member 7 (monocarboxylic acid transporter 2)
chr9_-_35062596 1.194 VCP
valosin containing protein
chr14_-_34253473 1.184 NM_138638
CFL2
cofilin 2 (muscle)
chr17_-_77824849 1.183 NM_001893
NM_139062
CSNK1D

casein kinase 1, delta

chr3_-_49370755 1.180 NM_000581
NM_201397
GPX1

glutathione peroxidase 1

chr3_+_39124155 1.164 NM_001105513
NM_145755
TTC21A

tetratricopeptide repeat domain 21A

chr12_+_120635021 1.163 NM_001080825
TMEM120B
transmembrane protein 120B
chr7_-_130443379 1.133 FLJ43663
hypothetical LOC378805
chr7_-_37922902 1.126 SFRP4
secreted frizzled-related protein 4
chr22_+_34107087 1.124 HMOX1
heme oxygenase (decycling) 1
chr9_-_35062578 1.118 VCP
valosin containing protein
chr12_+_970613 1.114 NM_178039
NM_178040
ERC1

ELKS/RAB6-interacting/CAST family member 1

chr21_+_37367432 1.102 NM_001001894
TTC3
tetratricopeptide repeat domain 3
chr14_+_100362236 1.096 MEG3
maternally expressed 3 (non-protein coding)
chr11_+_69165159 1.094 CCND1
cyclin D1
chr1_-_158091296 1.079 C1orf204
chromosome 1 open reading frame 204
chr3_-_39124036 1.075 GORASP1
golgi reassembly stacking protein 1, 65kDa
chr7_-_129379947 1.065 NM_003344
NM_182697
UBE2H

ubiquitin-conjugating enzyme E2H (UBC8 homolog, yeast)

chr22_+_34107051 1.064 NM_002133
HMOX1
heme oxygenase (decycling) 1
chr7_-_37923040 1.058 NM_003014
SFRP4
secreted frizzled-related protein 4
chr18_+_54682261 1.056 ZNF532
zinc finger protein 532
chr2_-_1727292 1.055 NM_012293
PXDN
peroxidasin homolog (Drosophila)
chr6_+_1336077 1.053


chr17_+_77529070 1.049 ASPSCR1
alveolar soft part sarcoma chromosome region, candidate 1
chr13_-_44048391 1.035 TSC22D1
TSC22 domain family, member 1
chr16_-_65775326 1.020 NM_001040715
KIAA0895L
KIAA0895-like
chr21_-_43671355 1.016 NM_173354
SIK1
salt-inducible kinase 1
chr19_+_52451570 1.014 NM_015603
CCDC9
coiled-coil domain containing 9
chr14_+_92869317 1.013 NM_020818
KIAA1409
KIAA1409
chr5_+_170221441 1.008 RANBP17
RAN binding protein 17
chr19_+_52451642 1.001 CCDC9
coiled-coil domain containing 9
chr3_+_101694098 1.001 NM_018004
TMEM45A
transmembrane protein 45A
chr10_-_98336548 0.997 TM9SF3
transmembrane 9 superfamily member 3
chr1_-_59020875 0.994 JUN
jun proto-oncogene
chr7_+_128166581 0.988 NM_001130674
NM_001219
CALU

calumenin

chr2_-_198248828 0.985 NM_144629
RFTN2
raftlin family member 2
chr6_-_75972286 0.985 NM_004370
NM_080645
COL12A1

collagen, type XII, alpha 1

chr22_+_37193961 0.984 NM_006855
NM_016657
KDELR3

KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3

chr9_-_74169649 0.984 NM_001102420
NM_001102421
NM_006007
ZFAND5


zinc finger, AN1-type domain 5


chr19_-_45888259 0.983 NM_004756
NUMBL
numb homolog (Drosophila)-like
chr20_-_2769245 0.983 NM_022760
FAM113A
family with sequence similarity 113, member A
chr12_+_20413445 0.979 NM_000921
PDE3A
phosphodiesterase 3A, cGMP-inhibited
chr6_-_86409701 0.973 NM_001159677
NM_006372
SYNCRIP

synaptotagmin binding, cytoplasmic RNA interacting protein

chr6_-_33864863 0.971 LEMD2
LEM domain containing 2
chr19_-_18493847 0.970 ELL
elongation factor RNA polymerase II
chr7_+_30140868 0.967 NM_152793
C7orf41
chromosome 7 open reading frame 41
chr16_+_2510323 0.966 NM_001145815
NM_015944
AMDHD2

amidohydrolase domain containing 2

chr6_-_90119068 0.961 UBE2J1
ubiquitin-conjugating enzyme E2, J1 (UBC6 homolog, yeast)
chr10_+_99486881 0.961 ZFYVE27
zinc finger, FYVE domain containing 27
chr12_-_51759400 0.960 SPRYD3
SPRY domain containing 3
chr4_-_119976736 0.959 NM_014822
SEC24D
SEC24 family, member D (S. cerevisiae)
chr4_-_119976631 0.957 SEC24D
SEC24 family, member D (S. cerevisiae)
chr7_+_150560459 0.957 NM_019015
CHPF2
chondroitin polymerizing factor 2
chr16_+_15435825 0.956 NM_033201
C16orf45
chromosome 16 open reading frame 45
chr11_+_101291134 0.954 KIAA1377
KIAA1377
chr18_+_9903954 0.954 NM_003574
NM_194434
VAPA

VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa

chr5_+_53849251 0.952 NM_001145427
NM_001102575
NM_052870
SNX18


sorting nexin 18


chr15_-_53667800 0.951 PYGO1
pygopus homolog 1 (Drosophila)
chr10_-_131652364 0.945 EBF3
early B-cell factor 3
chr12_+_70434927 0.945 RAB21
RAB21, member RAS oncogene family
chr16_-_5087740 0.937 NM_201400
NM_201598
FAM86A

family with sequence similarity 86, member A

chr6_-_90119158 0.937 UBE2J1
ubiquitin-conjugating enzyme E2, J1 (UBC6 homolog, yeast)
chr4_-_114901789 0.927 CAMK2D
calcium/calmodulin-dependent protein kinase II delta

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.76 2.39e-07 GO:0033036 macromolecule localization
1.85 3.53e-07 GO:0008104 protein localization
1.92 1.73e-06 GO:0015031 protein transport
1.91 2.06e-06 GO:0045184 establishment of protein localization
8.71 1.51e-05 GO:0048199 vesicle targeting, to, from or within Golgi
1.13 1.92e-05 GO:0009987 cellular process
1.31 4.94e-05 GO:0044260 cellular macromolecule metabolic process
1.22 5.51e-05 GO:0050794 regulation of cellular process
1.66 6.18e-05 GO:0051641 cellular localization
1.41 1.21e-04 GO:0048518 positive regulation of biological process
1.27 1.97e-04 GO:0043170 macromolecule metabolic process
1.43 2.24e-04 GO:0048522 positive regulation of cellular process
2.03 2.63e-04 GO:0070727 cellular macromolecule localization
6.34 2.85e-04 GO:0006903 vesicle targeting
3.12 4.77e-04 GO:0048193 Golgi vesicle transport
2.01 4.79e-04 GO:0034613 cellular protein localization
1.75 7.00e-04 GO:0006351 transcription, DNA-dependent
1.19 8.32e-04 GO:0050789 regulation of biological process
1.33 8.44e-04 GO:0080090 regulation of primary metabolic process
1.18 9.54e-04 GO:0065007 biological regulation
1.32 1.29e-03 GO:0031323 regulation of cellular metabolic process
4.90 2.72e-03 GO:0051650 establishment of vesicle localization
1.21 3.65e-03 GO:0044237 cellular metabolic process
1.28 3.97e-03 GO:0019222 regulation of metabolic process
1.73 4.01e-03 GO:0046907 intracellular transport
1.59 5.43e-03 GO:0051649 establishment of localization in cell
1.45 1.08e-02 GO:0009059 macromolecule biosynthetic process
1.35 1.12e-02 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.45 1.46e-02 GO:0034645 cellular macromolecule biosynthetic process
1.61 1.51e-02 GO:0032774 RNA biosynthetic process
1.39 1.56e-02 GO:0048523 negative regulation of cellular process
1.34 1.65e-02 GO:0031326 regulation of cellular biosynthetic process
1.70 1.79e-02 GO:0016192 vesicle-mediated transport
1.33 1.79e-02 GO:0051171 regulation of nitrogen compound metabolic process
1.19 1.82e-02 GO:0044238 primary metabolic process
5.94 2.11e-02 GO:0006901 vesicle coating
1.35 2.15e-02 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.47 2.60e-02 GO:0009653 anatomical structure morphogenesis
1.83 2.68e-02 GO:0010942 positive regulation of cell death
5.70 3.10e-02 GO:0006900 membrane budding
1.41 3.21e-02 GO:0010467 gene expression
1.96 3.27e-02 GO:0006886 intracellular protein transport
1.32 3.41e-02 GO:0009889 regulation of biosynthetic process
1.60 3.92e-02 GO:0050793 regulation of developmental process
1.28 4.07e-02 GO:0060255 regulation of macromolecule metabolic process
1.40 4.60e-02 GO:0006464 protein modification process
3.89 4.66e-02 GO:0051648 vesicle localization
1.33 4.70e-02 GO:0010468 regulation of gene expression

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.18 8.18e-13 GO:0044424 intracellular part
1.16 4.77e-12 GO:0005622 intracellular
1.23 1.33e-11 GO:0043227 membrane-bounded organelle
1.23 1.64e-11 GO:0043231 intracellular membrane-bounded organelle
1.19 1.31e-09 GO:0043226 organelle
1.19 1.32e-09 GO:0043229 intracellular organelle
1.28 2.73e-07 GO:0044446 intracellular organelle part
1.28 2.82e-07 GO:0044422 organelle part
1.19 1.30e-06 GO:0005737 cytoplasm
1.24 9.69e-06 GO:0044444 cytoplasmic part
1.25 3.50e-05 GO:0005634 nucleus
1.44 9.63e-05 GO:0031090 organelle membrane
1.62 8.52e-04 GO:0005794 Golgi apparatus
1.47 1.12e-03 GO:0012505 endomembrane system
1.56 2.47e-03 GO:0005783 endoplasmic reticulum
1.76 4.27e-03 GO:0044431 Golgi apparatus part
1.36 5.31e-03 GO:0044428 nuclear part
1.84 5.96e-03 GO:0000139 Golgi membrane
1.37 2.14e-02 GO:0031981 nuclear lumen
1.58 2.55e-02 GO:0031982 vesicle
1.59 2.69e-02 GO:0031410 cytoplasmic vesicle
4.06 4.58e-02 GO:0030120 vesicle coat
6.79 4.77e-02 GO:0030663 COPI coated vesicle membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.23 3.56e-07 GO:0005515 protein binding
1.69 8.46e-05 GO:0001071 nucleic acid binding transcription factor activity
1.69 8.46e-05 GO:0003700 sequence-specific DNA binding transcription factor activity
1.68 1.13e-04 GO:0030528 transcription regulator activity
1.11 2.16e-04 GO:0005488 binding
1.66 1.62e-02 GO:0043565 sequence-specific DNA binding
2.00 3.45e-02 GO:0005083 small GTPase regulator activity
1.31 4.13e-02 GO:0003677 DNA binding