Motif ID: CREB1.p2

Z-value: 1.808


Transcription factors associated with CREB1.p2:

Gene SymbolEntrez IDGene Name
CREB1 1385 cAMP responsive element binding protein 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
CREB1chr2_+_208103001-0.039.2e-01Click!


Activity profile for motif CREB1.p2.

activity profile for motif CREB1.p2


Sorted Z-values histogram for motif CREB1.p2

Sorted Z-values for motif CREB1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of CREB1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr19_+_58750305 2.302 NM_001079907
 ZNF331
zinc finger protein 331
chr2_-_156897286 2.004 NM_006186
 NR4A2
nuclear receptor subfamily 4, group A, member 2
chr5_+_148186348 1.563 NM_000024
 ADRB2
adrenergic, beta-2-, receptor, surface
chr12_-_113328271 1.480 NM_181486
 TBX5
T-box 5
chr4_+_75529716 1.458 NM_001657
 AREG
amphiregulin
chr19_+_50663089 1.446 NM_001114171
NM_006732
 FOSB

FBJ murine osteosarcoma viral oncogene homolog B

chr1_+_204875374 1.361 NM_001004023
NM_003582
 DYRK3

dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3

chr11_-_119504726 1.313 TRIM29
tripartite motif containing 29
chr19_-_10202947 1.301 NM_004230
 S1PR2
sphingosine-1-phosphate receptor 2
chr20_+_51023159 1.282 TSHZ2
teashirt zinc finger homeobox 2
chr1_+_119484529 1.265


chr12_-_10657397 1.251 NM_018048
 MAGOHB
mago-nashi homolog B (Drosophila)
chr5_-_133332173 1.241 NM_020199
 C5orf15
chromosome 5 open reading frame 15
chr4_-_187884721 1.218


chr14_-_49399317 1.215 RN7SL2
RNA, 7SL, cytoplasmic 2
chr1_-_119484733 1.178 NM_015836
NM_201263
 WARS2

tryptophanyl tRNA synthetase 2, mitochondrial

chr11_-_116474196 1.166 NM_025164
 SIK3
SIK family kinase 3
chr1_+_204875671 1.136 DYRK3
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
chr4_+_75699652 1.116 NM_001657
 AREG
amphiregulin
chr4_+_152549776 1.089 NM_001109977
 FAM160A1
family with sequence similarity 160, member A1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 33 entries
enrichment   p-value GO term description
3.30 1.07e-04 GO:0051028 mRNA transport
3.03 3.83e-04 GO:0006403 RNA localization
3.02 7.08e-04 GO:0050657 nucleic acid transport
3.02 7.08e-04 GO:0050658 RNA transport
3.02 7.08e-04 GO:0051236 establishment of RNA localization
2.60 1.39e-02 GO:0015931 nucleobase, nucleoside, nucleotide and nucleic acid transport
2.50 1.00e-03 GO:0000375 RNA splicing, via transesterification reactions
2.49 1.55e-03 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.49 1.55e-03 GO:0000398 nuclear mRNA splicing, via spliceosome
2.11 2.79e-04 GO:0006397 mRNA processing
2.08 8.75e-03 GO:0008380 RNA splicing
2.04 2.34e-02 GO:0006366 transcription from RNA polymerase II promoter
1.96 6.59e-06 GO:0006396 RNA processing
1.80 8.36e-03 GO:0016071 mRNA metabolic process
1.59 2.73e-02 GO:0033554 cellular response to stress
1.58 1.15e-09 GO:0090304 nucleic acid metabolic process
1.57 2.11e-07 GO:0010467 gene expression
1.56 4.53e-06 GO:0009059 macromolecule biosynthetic process
1.56 5.61e-06 GO:0034645 cellular macromolecule biosynthetic process
1.55 5.12e-06 GO:0016070 RNA metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 26 entries
enrichment   p-value GO term description
2.47 1.33e-02 GO:0005681 spliceosomal complex
2.12 1.09e-02 GO:0016604 nuclear body
2.06 1.45e-06 GO:0005730 nucleolus
1.75 8.57e-10 GO:0005654 nucleoplasm
1.72 1.36e-13 GO:0031981 nuclear lumen
1.68 7.06e-15 GO:0044428 nuclear part
1.65 2.30e-03 GO:0044451 nucleoplasm part
1.61 2.39e-12 GO:0070013 intracellular organelle lumen
1.58 7.70e-12 GO:0031974 membrane-enclosed lumen
1.58 1.31e-11 GO:0043233 organelle lumen
1.36 6.09e-15 GO:0005634 nucleus
1.35 5.36e-14 GO:0044446 intracellular organelle part
1.34 1.41e-13 GO:0044422 organelle part
1.34 2.01e-06 GO:0032991 macromolecular complex
1.34 4.85e-03 GO:0005829 cytosol
1.31 3.67e-04 GO:0043234 protein complex
1.29 1.02e-22 GO:0043231 intracellular membrane-bounded organelle
1.29 1.53e-22 GO:0043227 membrane-bounded organelle
1.23 6.40e-17 GO:0043229 intracellular organelle
1.23 1.89e-06 GO:0044444 cytoplasmic part

Gene overrepresentation in function category:

Showing 1 to 11 of 11 entries
enrichment   p-value GO term description
1.61 2.13e-03 GO:0003723 RNA binding
1.41 5.71e-04 GO:0035639 purine ribonucleoside triphosphate binding
1.39 1.54e-03 GO:0017076 purine nucleotide binding
1.39 1.64e-03 GO:0032553 ribonucleotide binding
1.39 1.64e-03 GO:0032555 purine ribonucleotide binding
1.38 1.49e-04 GO:0000166 nucleotide binding
1.37 4.53e-02 GO:0005524 ATP binding
1.30 3.22e-04 GO:0003676 nucleic acid binding
1.21 6.66e-04 GO:0003824 catalytic activity
1.20 1.12e-06 GO:0005515 protein binding
1.09 7.35e-04 GO:0005488 binding