Motif ID: ELF1,2,4.p2

Z-value: 2.718


Transcription factors associated with ELF1,2,4.p2:

Gene SymbolEntrez IDGene Name
ELF1 1997 E74-like factor 1 (ets domain transcription factor)
ELF2 1998 E74-like factor 2 (ets domain transcription factor)
ELF4 2000 E74-like factor 4 (ets domain transcription factor)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ELF1chr13_-_404541880.836.6e-05Click!
ELF2chr4_-_140317686-0.485.8e-02Click!
ELF4chrX_-_129072333-0.146.1e-01Click!


Activity profile for motif ELF1,2,4.p2.

activity profile for motif ELF1,2,4.p2


Sorted Z-values histogram for motif ELF1,2,4.p2

Sorted Z-values for motif ELF1,2,4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ELF1,2,4.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr13_+_110653407 3.818 ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr3_-_184756101 3.129 NM_130446
 KLHL6
kelch-like 6 (Drosophila)
chr1_+_32489426 2.865 NM_005356
 LCK
lymphocyte-specific protein tyrosine kinase
chr5_+_61910318 2.825 NM_181506
 LRRC70
leucine rich repeat containing 70
chr17_-_59451662 2.673 NM_001099786
NM_001099787
NM_001099788
NM_001099789
 ICAM2



intercellular adhesion molecule 2



chr17_-_18890963 2.628 NM_006613
 GRAP
GRB2-related adaptor protein
chr14_+_75058518 2.243 NM_006399
 BATF
basic leucine zipper transcription factor, ATF-like
chr14_+_75058591 2.243 BATF
basic leucine zipper transcription factor, ATF-like
chr7_+_150044530 2.122 NM_130759
 GIMAP1
GTPase, IMAP family member 1
chr2_-_242205556 1.993 NM_001164356
 THAP4
THAP domain containing 4
chr16_+_48865521 1.973 ADCY7
adenylate cyclase 7
chr9_-_116190038 1.938 AKNA
AT-hook transcription factor
chr9_+_115303527 1.880 NM_130795
 RGS3
regulator of G-protein signaling 3
chr3_+_120799411 1.875 NM_015900
 PLA1A
phospholipase A1 member A
chr21_+_25856311 1.866 MIR155HG
MIR155 host gene (non-protein coding)
chr3_-_50335113 1.846 NM_003773
NM_033158
 HYAL2

hyaluronoglucosaminidase 2

chr3_+_120495906 1.819 NM_020754
 ARHGAP31
Rho GTPase activating protein 31
chr12_-_6668880 1.742 NM_001039917
NM_001039919
NM_001039920
NM_001135734
 ZNF384



zinc finger protein 384



chr9_-_122731263 1.733 NM_001190945
 TRAF1
TNF receptor-associated factor 1
chr1_-_224993498 1.702 NM_002221
 ITPKB
inositol 1,4,5-trisphosphate 3-kinase B

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 74 entries
enrichment   p-value GO term description
2.02 3.86e-02 GO:0006368 transcription elongation from RNA polymerase II promoter
1.94 1.46e-02 GO:0006354 transcription elongation, DNA-dependent
1.72 8.38e-03 GO:0019058 viral infectious cycle
1.65 2.80e-03 GO:0006260 DNA replication
1.62 3.18e-02 GO:0022415 viral reproductive process
1.61 1.26e-03 GO:0071156 regulation of cell cycle arrest
1.61 1.56e-03 GO:0000075 cell cycle checkpoint
1.58 1.36e-02 GO:0000375 RNA splicing, via transesterification reactions
1.58 1.71e-02 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
1.58 1.71e-02 GO:0000398 nuclear mRNA splicing, via spliceosome
1.56 6.38e-07 GO:0016032 viral reproduction
1.56 3.37e-04 GO:0006366 transcription from RNA polymerase II promoter
1.51 5.92e-05 GO:0006397 mRNA processing
1.50 3.72e-03 GO:0008380 RNA splicing
1.48 1.64e-06 GO:0016071 mRNA metabolic process
1.47 6.19e-06 GO:0006974 response to DNA damage stimulus
1.47 1.22e-02 GO:0006412 translation
1.44 9.91e-07 GO:0006396 RNA processing
1.44 7.06e-06 GO:0000278 mitotic cell cycle
1.39 3.42e-04 GO:0006259 DNA metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 37 entries
enrichment   p-value GO term description
2.32 3.25e-02 GO:0030532 small nuclear ribonucleoprotein complex
2.01 2.71e-03 GO:0030117 membrane coat
2.01 2.71e-03 GO:0048475 coated membrane
1.79 1.17e-04 GO:0005681 spliceosomal complex
1.62 7.96e-13 GO:0030529 ribonucleoprotein complex
1.55 8.55e-03 GO:0005840 ribosome
1.40 3.19e-02 GO:0015629 actin cytoskeleton
1.39 5.83e-05 GO:0005694 chromosome
1.38 3.82e-04 GO:0005730 nucleolus
1.37 1.14e-17 GO:0031981 nuclear lumen
1.36 1.83e-11 GO:0005654 nucleoplasm
1.35 6.84e-20 GO:0044428 nuclear part
1.34 1.02e-02 GO:0044427 chromosomal part
1.33 4.00e-19 GO:0043233 organelle lumen
1.33 5.09e-19 GO:0031974 membrane-enclosed lumen
1.32 1.37e-17 GO:0070013 intracellular organelle lumen
1.28 1.66e-11 GO:0005829 cytosol
1.27 8.02e-03 GO:0044451 nucleoplasm part
1.25 4.66e-02 GO:0016023 cytoplasmic membrane-bounded vesicle
1.22 1.47e-09 GO:0043228 non-membrane-bounded organelle

Gene overrepresentation in function category:

Showing 1 to 9 of 9 entries
enrichment   p-value GO term description
1.92 1.01e-02 GO:0047485 protein N-terminus binding
1.55 2.92e-03 GO:0003713 transcription coactivator activity
1.48 1.82e-12 GO:0003723 RNA binding
1.40 7.29e-03 GO:0003712 transcription cofactor activity
1.39 8.57e-03 GO:0000988 protein binding transcription factor activity
1.39 8.57e-03 GO:0000989 transcription factor binding transcription factor activity
1.21 1.58e-11 GO:0003676 nucleic acid binding
1.16 4.75e-22 GO:0005515 protein binding
1.07 1.15e-10 GO:0005488 binding