Motif ID: ELK1,4_GABP{A,B1}.p3

Z-value: 4.011


Transcription factors associated with ELK1,4_GABP{A,B1}.p3:

Gene SymbolEntrez IDGene Name
ELK1 2002 ELK1, member of ETS oncogene family
ELK4 2005 ELK4, ETS-domain protein (SRF accessory protein 1)
GABPA 2551 GA binding protein transcription factor, alpha subunit 60kDa
GABPB1 2553 GA binding protein transcription factor, beta subunit 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
GABPAchr21_+_260291280.543.1e-02Click!
GABPB1chr15_-_48434567-0.421.0e-01Click!
ELK4chr1_-_203868622-0.194.9e-01Click!
ELK1chrX_-_47394937-0.068.1e-01Click!


Activity profile for motif ELK1,4_GABP{A,B1}.p3.

activity profile for motif ELK1,4_GABP{A,B1}.p3


Sorted Z-values histogram for motif ELK1,4_GABP{A,B1}.p3

Sorted Z-values for motif ELK1,4_GABP{A,B1}.p3



Network of associatons between targets according to the STRING database.



First level regulatory network of ELK1,4_GABP{A,B1}.p3

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_+_50318801 4.864 IKZF1
IKAROS family zinc finger 1 (Ikaros)
chr8_+_30721208 4.255 NM_005671
 UBXN8
UBX domain protein 8
chr1_+_20385164 4.128 NM_152376
 UBXN10
UBX domain protein 10
chr12_-_53153639 3.891 NM_144594
 GTSF1
gametocyte specific factor 1
chr12_-_53153613 3.850 GTSF1
gametocyte specific factor 1
chr12_+_118590039 3.673 NM_006253
 PRKAB1
protein kinase, AMP-activated, beta 1 non-catalytic subunit
chr9_-_133141726 3.600 NM_033387
 FAM78A
family with sequence similarity 78, member A
chr2_+_113648036 3.463 PSD4
pleckstrin and Sec7 domain containing 4
chr6_-_28475478 3.401 NM_001163391
 ZSCAN12
zinc finger and SCAN domain containing 12
chr19_+_17723285 3.391 NM_001161359
NM_015122
 FCHO1

FCH domain only 1

chr3_+_47004457 3.306 NBEAL2
neurobeachin-like 2
chr6_-_31728447 3.299 NM_004639
NM_080702
NM_080703
 BAG6


BCL2-associated athanogene 6


chr22_+_20350272 3.279 NM_014337
NM_148175
NM_148176
 PPIL2


peptidylprolyl isomerase (cyclophilin)-like 2


chrX_-_153632355 3.230 NM_001081573
NM_080612
 GAB3

GRB2-associated binding protein 3

chr15_+_72620570 3.215 NM_006465
 ARID3B
AT rich interactive domain 3B (BRIGHT-like)
chr2_+_169367345 3.073 NM_001039724
NM_001171632
NM_052946
 NOSTRIN


nitric oxide synthase trafficker


chr5_+_82409072 3.054 NM_003401
NM_022406
NM_022550
 XRCC4


X-ray repair complementing defective repair in Chinese hamster cells 4


chr10_-_43212681 3.036 HNRNPF
heterogeneous nuclear ribonucleoprotein F
chr6_-_33347563 2.951 NM_022553
 VPS52
vacuolar protein sorting 52 homolog (S. cerevisiae)
chr6_-_31728418 2.898 BAG6
BCL2-associated athanogene 6

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 134 entries
enrichment   p-value GO term description
2.69 1.32e-09 GO:0019080 viral genome expression
2.69 1.32e-09 GO:0019083 viral transcription
2.59 8.48e-09 GO:0006415 translational termination
2.53 1.61e-09 GO:0006414 translational elongation
2.49 1.52e-08 GO:0043241 protein complex disassembly
2.49 1.52e-08 GO:0043624 cellular protein complex disassembly
2.34 4.78e-15 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.34 4.78e-15 GO:0000398 nuclear mRNA splicing, via spliceosome
2.34 1.02e-07 GO:0032984 macromolecular complex disassembly
2.34 1.02e-07 GO:0034623 cellular macromolecular complex disassembly
2.32 3.52e-15 GO:0000375 RNA splicing, via transesterification reactions
2.28 3.95e-08 GO:0042254 ribosome biogenesis
2.28 2.07e-04 GO:0000216 M/G1 transition of mitotic cell cycle
2.28 3.21e-03 GO:0071158 positive regulation of cell cycle arrest
2.24 2.01e-08 GO:0019058 viral infectious cycle
2.24 1.09e-02 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
2.24 1.09e-02 GO:0072395 signal transduction involved in cell cycle checkpoint
2.24 1.09e-02 GO:0072401 signal transduction involved in DNA integrity checkpoint
2.24 1.09e-02 GO:0072404 signal transduction involved in G1/S transition checkpoint
2.24 1.09e-02 GO:0072413 signal transduction involved in mitotic cell cycle checkpoint

Gene overrepresentation in compartment category:

Showing 1 to 20 of 49 entries
enrichment   p-value GO term description
3.72 2.87e-02 GO:0005732 small nucleolar ribonucleoprotein complex
2.71 6.32e-04 GO:0022625 cytosolic large ribosomal subunit
2.64 9.87e-03 GO:0030532 small nuclear ribonucleoprotein complex
2.59 1.13e-08 GO:0071013 catalytic step 2 spliceosome
2.54 1.22e-02 GO:0022627 cytosolic small ribosomal subunit
2.52 2.87e-07 GO:0022626 cytosolic ribosome
2.46 3.15e-05 GO:0015934 large ribosomal subunit
2.32 2.42e-03 GO:0015935 small ribosomal subunit
2.29 4.07e-10 GO:0005681 spliceosomal complex
2.14 3.98e-11 GO:0005840 ribosome
2.11 8.69e-31 GO:0030529 ribonucleoprotein complex
2.06 4.11e-03 GO:0016591 DNA-directed RNA polymerase II, holoenzyme
2.04 2.47e-07 GO:0044445 cytosolic part
1.76 4.80e-14 GO:0005730 nucleolus
1.72 5.64e-05 GO:0016604 nuclear body
1.72 4.07e-02 GO:0016607 nuclear speck
1.56 6.94e-32 GO:0031981 nuclear lumen
1.53 3.20e-34 GO:0044428 nuclear part
1.52 2.57e-35 GO:0070013 intracellular organelle lumen
1.52 3.61e-19 GO:0005654 nucleoplasm

Gene overrepresentation in function category:

Showing 1 to 15 of 15 entries
enrichment   p-value GO term description
2.21 8.63e-10 GO:0003735 structural constituent of ribosome
1.91 6.87e-06 GO:0008168 methyltransferase activity
1.85 2.93e-05 GO:0016741 transferase activity, transferring one-carbon groups
1.65 2.35e-17 GO:0003723 RNA binding
1.29 1.92e-17 GO:0003676 nucleic acid binding
1.22 3.06e-05 GO:0000166 nucleotide binding
1.19 7.07e-23 GO:0005515 protein binding
1.19 2.63e-03 GO:0008270 zinc ion binding
1.19 1.00e-02 GO:0035639 purine ribonucleoside triphosphate binding
1.19 1.08e-02 GO:0017076 purine nucleotide binding
1.19 1.65e-02 GO:0032553 ribonucleotide binding
1.19 1.65e-02 GO:0032555 purine ribonucleotide binding
1.18 3.12e-03 GO:0003677 DNA binding
1.10 2.89e-02 GO:0003824 catalytic activity
1.09 2.82e-14 GO:0005488 binding