Motif ID: EP300.p2

Z-value: 3.190


Transcription factors associated with EP300.p2:

Gene SymbolEntrez IDGene Name
EP300 2033 E1A binding protein p300

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
EP300chr22_+_398177330.421.0e-01Click!


Activity profile for motif EP300.p2.

activity profile for motif EP300.p2


Sorted Z-values histogram for motif EP300.p2

Sorted Z-values for motif EP300.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of EP300.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_+_160964574 5.417 SCHIP1
schwannomin interacting protein 1
chr10_-_126839546 4.258 NM_001083914
 CTBP2
C-terminal binding protein 2
chr5_+_96024434 4.050 CAST
calpastatin
chr15_-_80125403 3.602 NM_032246
 MEX3B
mex-3 homolog B (C. elegans)
chr15_-_80125514 3.457 MEX3B
mex-3 homolog B (C. elegans)
chr13_+_113546841 3.388 NM_000820
 GAS6
growth arrest-specific 6
chr3_+_156280539 3.141 MME
membrane metallo-endopeptidase
chr8_-_145085616 3.023 NM_201384
 PLEC
plectin
chr13_+_113546897 2.941 GAS6
growth arrest-specific 6
chr8_+_106400322 2.918 NM_012082
 ZFPM2
zinc finger protein, multitype 2
chr1_+_179148935 2.882 NM_020950
 KIAA1614
KIAA1614
chr3_+_156280497 2.847 MME
membrane metallo-endopeptidase
chr13_-_43259032 2.780 NM_017993
 ENOX1
ecto-NOX disulfide-thiol exchanger 1
chr9_-_33437527 2.706 NM_004925
 AQP3
aquaporin 3 (Gill blood group)
chr8_+_22513043 2.678 NM_001013842
NM_001198827
NM_173686
 C8orf58


chromosome 8 open reading frame 58


chr4_+_183302105 2.565 ODZ3
odz, odd Oz/ten-m homolog 3 (Drosophila)
chr13_+_113546912 2.519 GAS6
growth arrest-specific 6
chr8_-_122722674 2.499 NM_005328
 HAS2
hyaluronan synthase 2
chr12_-_104153920 2.449 NM_018171
 APPL2
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
chr10_+_102782156 2.360 SFXN3
sideroflexin 3

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
1.23 6.74e-04 GO:0048522 positive regulation of cellular process
1.23 9.28e-03 GO:0030154 cell differentiation
1.22 1.28e-02 GO:0048869 cellular developmental process
1.21 7.69e-04 GO:0048518 positive regulation of biological process
1.12 3.76e-04 GO:0050794 regulation of cellular process
1.11 2.43e-04 GO:0065007 biological regulation
1.11 9.05e-04 GO:0050789 regulation of biological process

Gene overrepresentation in compartment category:

Showing 1 to 12 of 12 entries
enrichment   p-value GO term description
2.09 8.94e-04 GO:0030055 cell-substrate junction
2.09 6.92e-03 GO:0001726 ruffle
2.01 6.36e-03 GO:0005924 cell-substrate adherens junction
1.99 1.27e-02 GO:0005925 focal adhesion
1.92 6.46e-05 GO:0031252 cell leading edge
1.85 3.44e-03 GO:0005912 adherens junction
1.81 3.20e-03 GO:0070161 anchoring junction
1.67 3.67e-03 GO:0016323 basolateral plasma membrane
1.54 5.31e-06 GO:0030054 cell junction
1.54 2.37e-02 GO:0015629 actin cytoskeleton
1.27 7.08e-04 GO:0005856 cytoskeleton
1.12 2.90e-03 GO:0005634 nucleus

Gene overrepresentation in function category:

Showing 1 to 4 of 4 entries
enrichment   p-value GO term description
1.59 3.10e-03 GO:0003779 actin binding
1.51 2.25e-04 GO:0008092 cytoskeletal protein binding
1.11 3.97e-05 GO:0005515 protein binding
1.06 8.44e-04 GO:0005488 binding