Motif ID: ESR1.p2

Z-value: 2.321


Transcription factors associated with ESR1.p2:

Gene SymbolEntrez IDGene Name
ESR1 2099 estrogen receptor 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ESR1chr6_+_152053323-0.572.2e-02Click!


Activity profile for motif ESR1.p2.

activity profile for motif ESR1.p2


Sorted Z-values histogram for motif ESR1.p2

Sorted Z-values for motif ESR1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ESR1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_+_184257337 2.796 NM_024949
WWC2
WW and C2 domain containing 2
chr10_+_115428924 2.468 NM_033340
CASP7
caspase 7, apoptosis-related cysteine peptidase
chr7_+_1543644 2.409 MAFK
v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)
chr13_+_75108450 2.225 LMO7
LIM domain 7
chr4_+_151218862 2.153 NM_001040260
NM_001040261
DCLK2

doublecortin-like kinase 2

chr8_+_16929116 2.085 NM_181723
EFHA2
EF-hand domain family, member A2
chr13_-_32822759 2.074 STARD13
StAR-related lipid transfer (START) domain containing 13
chrX_+_117745551 2.067 NM_001560
IL13RA1
interleukin 13 receptor, alpha 1
chr3_-_129690056 1.980 NM_001145661
GATA2
GATA binding protein 2
chr9_+_89302574 1.873 NM_004938
DAPK1
death-associated protein kinase 1
chr7_+_45894480 1.746 NM_000596
IGFBP1
insulin-like growth factor binding protein 1
chr16_-_73842884 1.688 NM_001170717
NM_014567
BCAR1

breast cancer anti-estrogen resistance 1

chr2_+_238200922 1.674 NM_001137550
LRRFIP1
leucine rich repeat (in FLII) interacting protein 1
chr9_+_89302239 1.618 DAPK1
death-associated protein kinase 1
chr1_-_29322993 1.548 NM_001003682
TMEM200B
transmembrane protein 200B
chr12_-_123568781 1.528


chr19_+_15079141 1.478 NM_033025
SYDE1
synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chr17_-_30724732 1.464 NM_001104587
NM_001104588
NM_001104589
NM_001104590
NM_152270
SLFN11




schlafen family member 11




chr3_+_52504391 1.457 NM_015136
STAB1
stabilin 1
chr1_+_179148935 1.449 NM_020950
KIAA1614
KIAA1614

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
1.44 3.49e-02 GO:0032879 regulation of localization

Gene overrepresentation in compartment category:

Showing 1 to 5 of 5 entries
enrichment   p-value GO term description
3.46 3.55e-02 GO:0042641 actomyosin
1.73 2.87e-02 GO:0015629 actin cytoskeleton
1.13 9.92e-05 GO:0005737 cytoplasm
1.07 8.03e-03 GO:0044424 intracellular part
1.07 9.21e-03 GO:0005622 intracellular

Gene overrepresentation in function category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
1.45 3.87e-02 GO:0019899 enzyme binding
1.16 1.43e-05 GO:0005515 protein binding
1.08 2.62e-04 GO:0005488 binding