Motif ID: ESRRA.p2

Z-value: 3.193


Transcription factors associated with ESRRA.p2:

Gene SymbolEntrez IDGene Name
ESRRA 2101 estrogen-related receptor alpha

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ESRRAchr11_+_638296160.828.7e-05Click!


Activity profile for motif ESRRA.p2.

activity profile for motif ESRRA.p2


Sorted Z-values histogram for motif ESRRA.p2

Sorted Z-values for motif ESRRA.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ESRRA.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_-_143706265 8.301 PDE4DIP
phosphodiesterase 4D interacting protein
chr1_-_143706196 6.195 PDE4DIP
phosphodiesterase 4D interacting protein
chr22_-_22440054 5.295 NM_213720
 CHCHD10
coiled-coil-helix-coiled-coil-helix domain containing 10
chr2_-_175754366 5.120 NM_001002258
NM_001190329
NM_001689
 ATP5G3


ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)


chr1_+_29086206 4.831 EPB41
erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)
chr2_+_119905812 4.530 NM_183240
 TMEM37
transmembrane protein 37
chr1_+_29086156 4.529 NM_001166005
NM_001166007
NM_004437
NM_203342
NM_203343
 EPB41




erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)




chr12_-_52980984 4.366 NM_001136023
 NFE2
nuclear factor (erythroid-derived 2), 45kDa
chr12_-_52980914 4.194 NFE2
nuclear factor (erythroid-derived 2), 45kDa
chr6_+_34314545 4.123 NM_145905
 HMGA1
high mobility group AT-hook 1
chr3_-_49701085 3.939 NM_020998
 MST1
macrophage stimulating 1 (hepatocyte growth factor-like)
chr19_-_44518465 3.750 GMFG
glia maturation factor, gamma
chr15_-_89276657 3.523 NM_198527
 HDDC3
HD domain containing 3
chr4_-_40212670 3.372 NM_019027
 RBM47
RNA binding motif protein 47
chr19_-_44518516 3.223 NM_004877
 GMFG
glia maturation factor, gamma
chr12_-_55325912 3.221 ATP5B
ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide
chr5_-_1647617 3.063 SDHAP3
succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 3
chr20_+_37024383 3.059 NM_001190809
NM_021931
 DHX35

DEAH (Asp-Glu-Ala-His) box polypeptide 35

chr19_-_4486202 3.032 NM_001013706
 PLIN5
perilipin 5
chrX_+_65152004 3.029



Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 20 entries
enrichment   p-value GO term description
16.74 2.72e-02 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c
7.44 8.66e-03 GO:0015985 energy coupled proton transport, down electrochemical gradient
7.44 8.66e-03 GO:0015986 ATP synthesis coupled proton transport
7.23 3.45e-09 GO:0042773 ATP synthesis coupled electron transport
7.23 3.45e-09 GO:0042775 mitochondrial ATP synthesis coupled electron transport
6.83 3.22e-09 GO:0006119 oxidative phosphorylation
6.51 1.59e-05 GO:0006120 mitochondrial electron transport, NADH to ubiquinone
6.37 1.99e-16 GO:0022904 respiratory electron transport chain
6.09 4.58e-04 GO:0009060 aerobic respiration
5.49 2.57e-16 GO:0045333 cellular respiration
4.97 9.49e-14 GO:0022900 electron transport chain
4.92 4.18e-02 GO:0006084 acetyl-CoA metabolic process
3.65 5.81e-03 GO:0006839 mitochondrial transport
3.41 7.59e-12 GO:0015980 energy derivation by oxidation of organic compounds
2.91 2.51e-11 GO:0006091 generation of precursor metabolites and energy
2.59 1.57e-02 GO:0006732 coenzyme metabolic process
2.15 6.65e-11 GO:0055114 oxidation-reduction process
1.41 3.37e-05 GO:0006810 transport
1.39 1.22e-04 GO:0051234 establishment of localization
1.29 1.24e-02 GO:0051179 localization

Gene overrepresentation in compartment category:

Showing 1 to 20 of 22 entries
enrichment   p-value GO term description
6.89 1.11e-02 GO:0005753 mitochondrial proton-transporting ATP synthase complex
6.60 6.71e-13 GO:0070469 respiratory chain
6.59 8.44e-12 GO:0005746 mitochondrial respiratory chain
6.17 2.58e-02 GO:0045259 proton-transporting ATP synthase complex
6.01 9.06e-06 GO:0005747 mitochondrial respiratory chain complex I
6.01 9.06e-06 GO:0030964 NADH dehydrogenase complex
6.01 9.06e-06 GO:0045271 respiratory chain complex I
5.49 4.36e-17 GO:0044455 mitochondrial membrane part
4.43 4.59e-02 GO:0042645 mitochondrial nucleoid
4.28 2.06e-26 GO:0005743 mitochondrial inner membrane
4.03 3.10e-25 GO:0019866 organelle inner membrane
3.57 5.06e-25 GO:0031966 mitochondrial membrane
3.50 7.45e-25 GO:0005740 mitochondrial envelope
3.14 7.05e-28 GO:0044429 mitochondrial part
2.57 5.72e-17 GO:0031967 organelle envelope
2.55 6.88e-17 GO:0031975 envelope
2.54 4.06e-05 GO:0005759 mitochondrial matrix
2.39 5.92e-27 GO:0005739 mitochondrion
1.98 1.60e-02 GO:0005625 soluble fraction
1.45 9.26e-05 GO:0031090 organelle membrane

Gene overrepresentation in function category:

Showing 1 to 15 of 15 entries
enrichment   p-value GO term description
6.28 3.20e-03 GO:0004129 cytochrome-c oxidase activity
6.28 3.20e-03 GO:0015002 heme-copper terminal oxidase activity
6.28 3.20e-03 GO:0016675 oxidoreductase activity, acting on a heme group of donors
6.28 3.20e-03 GO:0016676 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
5.88 6.28e-05 GO:0003954 NADH dehydrogenase activity
5.88 6.28e-05 GO:0008137 NADH dehydrogenase (ubiquinone) activity
5.88 6.28e-05 GO:0050136 NADH dehydrogenase (quinone) activity
5.45 6.12e-05 GO:0016655 oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor
3.89 8.07e-06 GO:0015078 hydrogen ion transmembrane transporter activity
3.27 1.38e-02 GO:0016651 oxidoreductase activity, acting on NADH or NADPH
2.55 2.73e-03 GO:0015077 monovalent inorganic cation transmembrane transporter activity
2.49 3.10e-04 GO:0022890 inorganic cation transmembrane transporter activity
2.01 7.81e-07 GO:0016491 oxidoreductase activity
1.51 3.88e-02 GO:0022892 substrate-specific transporter activity
1.23 5.77e-04 GO:0003824 catalytic activity