Motif ID: ETS1,2.p2

Z-value: 2.644


Transcription factors associated with ETS1,2.p2:

Gene SymbolEntrez IDGene Name
ETS1 2113 v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)
ETS2 2114 v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ETS2chr21_+_39099717-0.543.2e-02Click!
ETS1chr11_-_1278970980.381.5e-01Click!


Activity profile for motif ETS1,2.p2.

activity profile for motif ETS1,2.p2


Sorted Z-values histogram for motif ETS1,2.p2

Sorted Z-values for motif ETS1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ETS1,2.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_+_49562866 5.399 WDFY4
WDFY family member 4
chr1_-_31003260 4.945 NM_006762
 LAPTM5
lysosomal protein transmembrane 5
chr3_-_184756101 4.891 NM_130446
 KLHL6
kelch-like 6 (Drosophila)
chr1_-_31003181 4.860 LAPTM5
lysosomal protein transmembrane 5
chr9_-_129707392 4.763 LOC100131355
ST6GALNAC6
hypothetical protein LOC100131355
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr4_+_2783764 4.275 SH3BP2
SH3-domain binding protein 2
chr4_+_2783743 3.927 NM_001145855
 SH3BP2
SH3-domain binding protein 2
chr19_-_10311262 3.835 NM_002162
 ICAM3
intercellular adhesion molecule 3
chr22_+_35586950 3.709 NM_000631
NM_013416
 NCF4

neutrophil cytosolic factor 4, 40kDa

chr14_+_20319049 3.689 NM_005615
 RNASE6
ribonuclease, RNase A family, k6
chr16_+_29581783 3.689 NM_001030288
 SPN
sialophorin
chr7_+_50318801 3.682 IKZF1
IKAROS family zinc finger 1 (Ikaros)
chr3_+_120799411 3.665 NM_015900
 PLA1A
phospholipase A1 member A
chr6_-_11490487 3.487 NM_001142393
 NEDD9
neural precursor cell expressed, developmentally down-regulated 9
chrX_+_65152004 3.310


chr3_+_47004457 3.103 NBEAL2
neurobeachin-like 2
chr16_-_29664765 3.093 NM_175900
 C16orf54
chromosome 16 open reading frame 54
chr7_-_3049872 3.069 NM_032415
 CARD11
caspase recruitment domain family, member 11
chr8_+_75066117 3.006 NM_001195797
NM_015364
 LY96

lymphocyte antigen 96

chr2_-_242205556 2.991 NM_001164356
 THAP4
THAP domain containing 4

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 72 entries
enrichment   p-value GO term description
3.90 1.96e-02 GO:0050853 B cell receptor signaling pathway
2.74 5.55e-05 GO:0042113 B cell activation
2.47 3.29e-02 GO:0050864 regulation of B cell activation
2.32 1.82e-03 GO:0050851 antigen receptor-mediated signaling pathway
2.23 1.91e-03 GO:0002768 immune response-regulating cell surface receptor signaling pathway
2.20 5.75e-03 GO:0002429 immune response-activating cell surface receptor signaling pathway
2.14 2.46e-06 GO:0046649 lymphocyte activation
2.14 1.67e-02 GO:0032944 regulation of mononuclear cell proliferation
2.14 2.92e-02 GO:0030098 lymphocyte differentiation
2.11 2.29e-03 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB cascade
2.10 3.64e-02 GO:0050670 regulation of lymphocyte proliferation
2.08 3.51e-02 GO:0070663 regulation of leukocyte proliferation
2.04 7.57e-07 GO:0045321 leukocyte activation
2.03 3.48e-04 GO:0051251 positive regulation of lymphocyte activation
2.03 5.67e-03 GO:0050870 positive regulation of T cell activation
2.01 5.37e-03 GO:0043122 regulation of I-kappaB kinase/NF-kappaB cascade
1.99 2.71e-02 GO:0002521 leukocyte differentiation
1.97 5.66e-04 GO:0050867 positive regulation of cell activation
1.96 7.47e-04 GO:0002696 positive regulation of leukocyte activation
1.94 1.43e-04 GO:0051249 regulation of lymphocyte activation

Gene overrepresentation in compartment category:

Showing 1 to 4 of 4 entries
enrichment   p-value GO term description
1.26 1.56e-02 GO:0005654 nucleoplasm
1.11 1.60e-02 GO:0005634 nucleus
1.06 2.84e-04 GO:0005622 intracellular
1.06 4.39e-04 GO:0044424 intracellular part

Gene overrepresentation in function category:

Showing 1 to 4 of 4 entries
enrichment   p-value GO term description
1.83 1.59e-02 GO:0005085 guanyl-nucleotide exchange factor activity
1.46 1.75e-02 GO:0060589 nucleoside-triphosphatase regulator activity
1.17 7.59e-12 GO:0005515 protein binding
1.06 4.04e-04 GO:0005488 binding