Motif ID: FEV.p2

Z-value: 2.954


Transcription factors associated with FEV.p2:

Gene SymbolEntrez IDGene Name
FEV 54738 FEV (ETS oncogene family)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
FEVchr2_-_2195585170.029.3e-01Click!


Activity profile for motif FEV.p2.

activity profile for motif FEV.p2


Sorted Z-values histogram for motif FEV.p2

Sorted Z-values for motif FEV.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FEV.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr22_+_25398690 6.601 LOC388889
hypothetical LOC388889
chr5_+_61910318 4.787 NM_181506
LRRC70
leucine rich repeat containing 70
chr11_-_72111027 3.601 NM_001135190
NM_015242
ARAP1

ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1

chr21_-_38792173 3.530 NM_001136155
NM_182918
ERG

v-ets erythroblastosis virus E26 oncogene homolog (avian)

chr3_-_184756101 3.500 NM_130446
KLHL6
kelch-like 6 (Drosophila)
chr13_+_110653407 3.420 ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr3_-_122862447 3.349 NM_005335
HCLS1
hematopoietic cell-specific Lyn substrate 1
chr5_+_40877053 3.245 NM_032587
CARD6
caspase recruitment domain family, member 6
chr3_+_120495906 3.217 NM_020754
ARHGAP31
Rho GTPase activating protein 31
chr3_-_122862391 3.199 HCLS1
hematopoietic cell-specific Lyn substrate 1
chr20_+_19818209 3.061 NM_018993
RIN2
Ras and Rab interactor 2
chr2_+_161701711 3.005 NM_004180
NM_133484
TANK

TRAF family member-associated NFKB activator

chr9_-_116190038 2.976 AKNA
AT-hook transcription factor
chr6_+_153060722 2.937 NM_025107
MYCT1
myc target 1
chr2_-_225519974 2.815 DOCK10
dedicator of cytokinesis 10
chr5_-_88214720 2.791 MEF2C
myocyte enhancer factor 2C
chr11_+_65164167 2.764 NM_153253
SIPA1
signal-induced proliferation-associated 1
chr4_-_153820535 2.669 NM_152680
TMEM154
transmembrane protein 154
chr6_-_32268267 2.631 GPSM3
G-protein signaling modulator 3
chr6_-_32268615 2.587 GPSM3
G-protein signaling modulator 3
chr1_-_79244948 2.578 NM_022159
ELTD1
EGF, latrophilin and seven transmembrane domain containing 1
chr13_-_32658215 2.569 NM_178007
STARD13
StAR-related lipid transfer (START) domain containing 13
chr3_-_150533948 2.569 NM_001184723
NM_138786
TM4SF18

transmembrane 4 L six family member 18

chr3_+_120799411 2.523 NM_015900
PLA1A
phospholipase A1 member A
chr10_-_98021144 2.486 NM_001114094
NM_013314
BLNK

B-cell linker

chr8_+_75066117 2.485 NM_001195797
NM_015364
LY96

lymphocyte antigen 96

chr14_+_62740878 2.342 NM_020663
RHOJ
ras homolog gene family, member J
chr12_+_12829807 2.303 NM_030817
APOLD1
apolipoprotein L domain containing 1
chr13_-_42464301 2.290 NM_001002264
NM_033255
EPSTI1

epithelial stromal interaction 1 (breast)

chr6_-_119137923 2.184 NM_001178035
C6orf204
chromosome 6 open reading frame 204
chr21_-_14840506 2.112 NM_022136
SAMSN1
SAM domain, SH3 domain and nuclear localization signals 1
chr5_-_54317102 2.105 NM_001135604
NM_007036
ESM1

endothelial cell-specific molecule 1

chr10_+_129735796 2.089 NM_130435
PTPRE
protein tyrosine phosphatase, receptor type, E
chr4_-_101658094 2.061 NM_001159694
NM_016242
EMCN

endomucin

chr6_+_139391570 2.047 C6orf115
chromosome 6 open reading frame 115
chrX_+_11687655 2.044 NM_006800
MSL3
male-specific lethal 3 homolog (Drosophila)
chr19_-_1083109 2.020 NM_001100122
SBNO2
strawberry notch homolog 2 (Drosophila)
chr22_+_35586950 2.005 NM_000631
NM_013416
NCF4

neutrophil cytosolic factor 4, 40kDa

chr2_-_45648608 1.961 SRBD1
S1 RNA binding domain 1
chr1_+_170077234 1.888 NM_001136127
NM_015569
DNM3

dynamin 3

chr7_+_18515488 1.870 HDAC9
histone deacetylase 9
chr17_-_59451662 1.863 NM_001099786
NM_001099787
NM_001099788
NM_001099789
ICAM2



intercellular adhesion molecule 2



chr11_-_65412409 1.855 NM_004214
NM_198897
FIBP

fibroblast growth factor (acidic) intracellular binding protein

chr7_+_18515440 1.850 HDAC9
histone deacetylase 9
chr12_+_74160779 1.846 NM_006851
GLIPR1
GLI pathogenesis-related 1
chr17_-_31441390 1.839 NM_002983
CCL3
chemokine (C-C motif) ligand 3
chr3_+_120496180 1.836 ARHGAP31
Rho GTPase activating protein 31
chr7_+_143683365 1.831 NM_005435
ARHGEF5
Rho guanine nucleotide exchange factor (GEF) 5
chr15_+_79376295 1.822 NM_004513
IL16
interleukin 16 (lymphocyte chemoattractant factor)
chr7_-_92615593 1.795 NM_152703
SAMD9L
sterile alpha motif domain containing 9-like
chr6_+_139391511 1.763 NM_021243
C6orf115
chromosome 6 open reading frame 115
chr12_-_6103945 1.753 NM_000552
VWF
von Willebrand factor
chr14_+_20319049 1.745 NM_005615
RNASE6
ribonuclease, RNase A family, k6
chr3_+_11242666 1.739 NM_001098211
HRH1
histamine receptor H1
chr12_-_52939584 1.714 NM_001127322
CBX5
chromobox homolog 5
chr6_-_111995213 1.709 NM_001164283
TRAF3IP2
TRAF3 interacting protein 2
chrX_-_44945025 1.682 NM_024689
NM_176819
CXorf36

chromosome X open reading frame 36

chr1_+_167604056 1.664 BLZF1
basic leucine zipper nuclear factor 1
chr1_+_167603817 1.659 NM_003666
BLZF1
basic leucine zipper nuclear factor 1
chr3_-_13032130 1.641


chr1_+_202000906 1.632 NM_001136190
NM_017773
LAX1

lymphocyte transmembrane adaptor 1

chr21_+_25856311 1.628 MIR155HG
MIR155 host gene (non-protein coding)
chr1_+_68070573 1.617


chr14_-_37795290 1.613 NM_175060
CLEC14A
C-type lectin domain family 14, member A
chr3_+_114733907 1.593 NM_017699
SIDT1
SID1 transmembrane family, member 1
chr11_-_76059435 1.589 NM_001128922
LRRC32
leucine rich repeat containing 32
chr19_-_56567602 1.574 NM_005601
NKG7
natural killer cell group 7 sequence
chr12_-_56157898 1.551 NM_001080156
ARHGAP9
Rho GTPase activating protein 9
chr2_+_45732416 1.541 NM_005400
PRKCE
protein kinase C, epsilon
chrX_-_50403412 1.540 SHROOM4
shroom family member 4
chr4_+_91035025 1.535 NM_007351
MMRN1
multimerin 1
chr1_-_23376860 1.526 LUZP1
leucine zipper protein 1
chr3_-_11585264 1.518 NM_001128221
VGLL4
vestigial like 4 (Drosophila)
chr10_+_35524835 1.514 NM_182721
NM_182722
NM_182723
NM_182724
NM_182725
CREM




cAMP responsive element modulator




chr6_+_10663934 1.493 NM_001491
GCNT2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr12_+_50592379 1.480 NM_001077401
ACVRL1
activin A receptor type II-like 1
chr7_-_3049872 1.477 NM_032415
CARD11
caspase recruitment domain family, member 11
chr2_+_134728299 1.476 NM_002410
MGAT5
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
chr15_-_68971665 1.473 NM_020147
THAP10
THAP domain containing 10
chr8_+_42248008 1.461 NM_001190721
IKBKB
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
chr7_-_143523582 1.458 NM_001003702
ARHGEF35
Rho guanine nucleotide exchange factor (GEF) 35
chr1_-_149004879 1.451 CTSS
cathepsin S
chr9_-_35744271 1.451 NM_001044264
MSMP
microseminoprotein, prostate associated
chr1_-_205161821 1.440 NM_001193338
NM_001142473
NM_005449
FAIM3


Fas apoptotic inhibitory molecule 3


chr17_-_26665220 1.433 NM_006495
EVI2B
ecotropic viral integration site 2B
chr12_-_15005761 1.424 NM_001175
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr1_-_167603623 1.419 NM_013330
NM_197972
NME7

non-metastatic cells 7, protein expressed in (nucleoside-diphosphate kinase)

chr4_+_39874921 1.418 NM_004310
RHOH
ras homolog gene family, member H
chr17_-_26672757 1.399 NM_001003927
NM_014210
EVI2A

ecotropic viral integration site 2A

chr11_+_101693403 1.398 NM_001165
NM_182962
BIRC3

baculoviral IAP repeat containing 3

chr1_+_43539239 1.366 NM_005424
TIE1
tyrosine kinase with immunoglobulin-like and EGF-like domains 1
chr5_-_59100091 1.365 PDE4D
phosphodiesterase 4D, cAMP-specific
chr2_-_175207521 1.361 NM_003387
WIPF1
WAS/WASL interacting protein family, member 1
chr7_+_134114701 1.359 NM_004342
NM_033138
NM_033157
CALD1


caldesmon 1


chr8_+_42247991 1.355 NM_001190720
IKBKB
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
chr3_-_120878910 1.343 NM_005694
COX17
COX17 cytochrome c oxidase assembly homolog (S. cerevisiae)
chr1_-_31003260 1.329 NM_006762
LAPTM5
lysosomal protein transmembrane 5
chr3_+_47004457 1.318 NBEAL2
neurobeachin-like 2
chr10_+_49562866 1.317 WDFY4
WDFY family member 4
chr17_-_26665194 1.316 EVI2B
ecotropic viral integration site 2B
chr3_+_25445071 1.314 RARB
retinoic acid receptor, beta
chr2_+_33514896 1.306 NM_170672
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr20_+_33223434 1.304 NM_006404
PROCR
protein C receptor, endothelial
chr6_-_31658044 1.299 NM_002341
NM_009588
LTB

lymphotoxin beta (TNF superfamily, member 3)

chr17_-_26665213 1.291 EVI2B
ecotropic viral integration site 2B
chrX_+_128741562 1.284 NM_018990
SASH3
SAM and SH3 domain containing 3
chr19_-_44518465 1.270 GMFG
glia maturation factor, gamma
chr1_+_159943385 1.268 NM_001184866
NM_001184867
NM_001184870
NM_001184871
NM_001184872
NM_001184873
NM_032738
FCRLA






Fc receptor-like A






chr6_-_42527760 1.262 NM_033502
TRERF1
transcriptional regulating factor 1
chr19_-_6432765 1.254 NM_024898
DENND1C
DENN/MADD domain containing 1C
chr2_+_130846263 1.252 PTPN18
protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
chr10_+_70517823 1.245 NM_002727
SRGN
serglycin
chr22_-_35970230 1.244 NM_002872
RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr8_+_42247954 1.236 NM_001190722
NM_001556
IKBKB

inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta

chrX_+_128741578 1.234 SASH3
SAM and SH3 domain containing 3
chr1_+_111544469 1.234


chr5_-_138842526 1.233 NM_198282
TMEM173
transmembrane protein 173
chr3_-_71262426 1.231 FOXP1
forkhead box P1
chr12_+_99118692 1.226 NM_022496
ACTR6
ARP6 actin-related protein 6 homolog (yeast)
chr19_-_51820133 1.225 NM_000960
PTGIR
prostaglandin I2 (prostacyclin) receptor (IP)
chr5_-_138842408 1.217 TMEM173
transmembrane protein 173
chr1_+_15955719 1.216 FBLIM1
filamin binding LIM protein 1
chr10_+_70517863 1.216 SRGN
serglycin
chr3_-_11598829 1.206 NM_001128220
VGLL4
vestigial like 4 (Drosophila)
chr3_-_46224791 1.199 NM_001295
CCR1
chemokine (C-C motif) receptor 1
chr17_-_40843530 1.197 ARHGAP27
Rho GTPase activating protein 27
chr1_+_32489426 1.195 NM_005356
LCK
lymphocyte-specific protein tyrosine kinase
chr17_-_26665144 1.193 EVI2B
ecotropic viral integration site 2B
chr17_-_16816113 1.189 NM_012452
TNFRSF13B
tumor necrosis factor receptor superfamily, member 13B
chr1_-_149004852 1.188 CTSS
cathepsin S
chr18_-_59137488 1.185 NM_000633
NM_000657
BCL2

B-cell CLL/lymphoma 2

chr8_+_42247978 1.185 IKBKB
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
chr2_-_175170674 1.176 WIPF1
WAS/WASL interacting protein family, member 1
chr22_-_35970133 1.168 RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chrX_-_43717864 1.166 NM_000266
NDP
Norrie disease (pseudoglioma)
chr2_-_242205556 1.162 NM_001164356
THAP4
THAP domain containing 4
chr6_-_30760413 1.159 KIAA1949
KIAA1949
chr3_+_52504391 1.159 NM_015136
STAB1
stabilin 1
chr9_+_115396020 1.158 NM_144489
RGS3
regulator of G-protein signaling 3
chr11_+_65164767 1.157 SIPA1
signal-induced proliferation-associated 1
chr1_+_109892708 1.157 NM_006496
GNAI3
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
chr1_-_246869181 1.154 NM_001001827
OR2T35
olfactory receptor, family 2, subfamily T, member 35
chr11_+_65026382 1.145


chr4_-_38482805 1.138 NM_003263
TLR1
toll-like receptor 1
chr11_-_101292462 1.136 NM_178127
ANGPTL5
angiopoietin-like 5
chr16_+_1523667 1.135 TMEM204
transmembrane protein 204
chr1_+_109892772 1.129 GNAI3
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
chr5_+_96237923 1.127 ERAP2
endoplasmic reticulum aminopeptidase 2
chr1_+_109892760 1.125 GNAI3
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
chr12_-_56159895 1.123 NM_032496
ARHGAP9
Rho GTPase activating protein 9
chr4_+_100957003 1.122 NM_014395
DAPP1
dual adaptor of phosphotyrosine and 3-phosphoinositides
chr1_-_111544603 1.116


chr1_+_109892741 1.116 GNAI3
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
chr22_-_39189369 1.110 MKL1
megakaryoblastic leukemia (translocation) 1
chr1_-_205012348 1.108 NM_000572
IL10
interleukin 10
chr3_+_52504410 1.106 STAB1
stabilin 1
chr15_+_68971835 1.094 NM_001199017
NM_017691
NM_001199018
LRRC49


leucine rich repeat containing 49


chrX_+_114734074 1.093 NM_001136025
NM_001172335
PLS3

plastin 3

chr19_+_17495109 1.090 NM_001098524
NM_173544
FAM129C

family with sequence similarity 129, member C

chr19_-_47328399 1.089 NM_002698
POU2F2
POU class 2 homeobox 2
chr13_-_27967215 1.089 NM_001159920
NM_001160030
NM_001160031
NM_002019
FLT1



fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)



chr16_+_1523658 1.088 TMEM204
transmembrane protein 204
chr4_-_152368492 1.087 SH3D19
SH3 domain containing 19
chr4_+_56509793 1.087 NM_025009
CEP135
centrosomal protein 135kDa
chr10_-_88707299 1.081 NM_024756
MMRN2
multimerin 2
chr19_-_4510713 1.080 SEMA6B
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
chr10_+_26767657 1.073 APBB1IP
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr12_-_68369322 1.073 NM_152439
BEST3
bestrophin 3
chr17_-_1495742 1.070 NM_003693
NM_145350
NM_145352
SCARF1


scavenger receptor class F, member 1


chr1_+_154389945 1.069 NM_001193300
NM_022367
NM_001193302
SEMA4A


sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A


chr12_-_52939636 1.066 NM_001127321
CBX5
chromobox homolog 5
chr9_-_129707392 1.061 LOC100131355
ST6GALNAC6
hypothetical protein LOC100131355
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr1_-_148936123 1.057 NM_018178
GOLPH3L
golgi phosphoprotein 3-like
chr10_+_49563520 1.055 NM_020945
WDFY4
WDFY family member 4
chr12_-_107745455 1.054 NM_001161331
SSH1
slingshot homolog 1 (Drosophila)
chr1_-_181826292 1.051 NM_000433
NM_001190789
NM_001190794
NCF2


neutrophil cytosolic factor 2


chr19_-_44518516 1.047 NM_004877
GMFG
glia maturation factor, gamma
chr7_-_143622188 1.046 ARHGEF5
Rho guanine nucleotide exchange factor (GEF) 5
chr17_-_60208083 1.045 LOC146880
hypothetical LOC146880
chr15_-_75259714 1.042 PEAK1
NKF3 kinase family member
chr1_-_208024491 1.037 NM_152485
C1orf74
chromosome 1 open reading frame 74
chr13_-_40454360 1.037 NM_001145353
ELF1
E74-like factor 1 (ets domain transcription factor)
chr10_-_13789628 1.033 FRMD4A
FERM domain containing 4A
chr12_-_47396724 1.029 NM_001240
CCNT1
cyclin T1
chr1_-_152394215 1.026 NM_001159484
NM_207308
NUP210L

nucleoporin 210kDa-like

chr4_+_74953971 1.025 NM_001511
CXCL1
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chr7_+_143028663 1.019 NM_173678
FAM115C
family with sequence similarity 115, member C
chr15_-_32398220 1.016 NM_005135
SLC12A6
solute carrier family 12 (potassium/chloride transporters), member 6
chr3_-_114176401 1.008 NM_138806
NM_138939
NM_138940
NM_170780
CD200R1



CD200 receptor 1



chr12_-_6642513 1.008 NM_001127582
NM_001127583
NM_001127584
NM_001127585
NM_001127586
NM_016162
ING4





inhibitor of growth family, member 4





chr9_+_94766379 1.008 FGD3
FYVE, RhoGEF and PH domain containing 3
chr1_-_149004916 1.007 NM_004079
CTSS
cathepsin S
chr15_-_78050515 0.991 NM_001114735
NM_004049
BCL2A1

BCL2-related protein A1

chr7_-_44985175 0.989 MYO1G
myosin IG
chr7_-_26870572 0.986 NM_003930
SKAP2
src kinase associated phosphoprotein 2
chr1_+_149309703 0.986 NM_144618
GABPB2
GA binding protein transcription factor, beta subunit 2
chr21_+_29439768 0.984 C21orf7
chromosome 21 open reading frame 7
chr1_-_173428455 0.984 NM_001162895
NM_014656
NM_001162893
NM_001162894
KIAA0040



KIAA0040



chr7_-_44985202 0.981 NM_033054
MYO1G
myosin IG
chr4_-_38710376 0.974 NM_024943
TMEM156
transmembrane protein 156

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.78 1.24e-13 GO:0001775 cell activation
1.22 1.88e-12 GO:0044260 cellular macromolecule metabolic process
1.96 1.68e-09 GO:0045321 leukocyte activation
1.20 2.10e-09 GO:0051716 cellular response to stimulus
1.29 2.18e-09 GO:0090304 nucleic acid metabolic process
1.25 3.44e-09 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.08 1.87e-08 GO:0009987 cellular process
1.17 2.08e-08 GO:0043170 macromolecule metabolic process
1.29 2.72e-07 GO:0048583 regulation of response to stimulus
1.20 3.55e-07 GO:0007165 signal transduction
1.93 1.39e-06 GO:0046649 lymphocyte activation
1.24 1.98e-06 GO:0006950 response to stress
2.33 2.10e-06 GO:0050851 antigen receptor-mediated signaling pathway
1.28 2.22e-06 GO:0006464 protein modification process
1.42 3.64e-06 GO:0033554 cellular response to stress
1.55 3.81e-06 GO:0006974 response to DNA damage stimulus
1.84 3.95e-06 GO:0048011 nerve growth factor receptor signaling pathway
1.32 4.38e-06 GO:0035556 intracellular signal transduction
1.26 4.64e-06 GO:0043412 macromolecule modification
1.28 8.67e-06 GO:0016070 RNA metabolic process
1.21 1.08e-05 GO:0071841 cellular component organization or biogenesis at cellular level
1.18 1.22e-05 GO:0071840 cellular component organization or biogenesis
1.58 2.48e-05 GO:0016032 viral reproduction
1.11 3.22e-05 GO:0050794 regulation of cellular process
2.15 3.23e-05 GO:0002768 immune response-regulating cell surface receptor signaling pathway
1.31 5.01e-05 GO:0002376 immune system process
1.17 5.41e-05 GO:0023052 signaling
1.86 5.63e-05 GO:0002764 immune response-regulating signaling pathway
1.41 6.34e-05 GO:0006955 immune response
2.14 6.94e-05 GO:0002429 immune response-activating cell surface receptor signaling pathway
1.11 8.31e-05 GO:0044237 cellular metabolic process
1.21 9.17e-05 GO:0044267 cellular protein metabolic process
1.30 1.13e-04 GO:0051641 cellular localization
1.85 1.14e-04 GO:0002757 immune response-activating signal transduction
1.74 1.25e-04 GO:0030168 platelet activation
2.00 1.36e-04 GO:0002521 leukocyte differentiation
1.10 1.47e-04 GO:0050789 regulation of biological process
1.32 1.76e-04 GO:0051649 establishment of localization in cell
2.14 2.19e-04 GO:0030098 lymphocyte differentiation
1.51 3.38e-04 GO:0050776 regulation of immune response
1.38 3.48e-04 GO:0046907 intracellular transport
1.56 4.44e-04 GO:0044419 interspecies interaction between organisms
1.19 4.54e-04 GO:0048518 positive regulation of biological process
1.50 4.92e-04 GO:0002684 positive regulation of immune system process
1.47 4.97e-04 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.09 5.06e-04 GO:0065007 biological regulation
1.16 5.42e-04 GO:0016043 cellular component organization
1.27 6.03e-04 GO:0009966 regulation of signal transduction
1.82 6.06e-04 GO:0051251 positive regulation of lymphocyte activation
1.25 6.43e-04 GO:0006996 organelle organization
1.19 6.47e-04 GO:0071842 cellular component organization at cellular level
2.26 8.60e-04 GO:0042113 B cell activation
1.23 8.87e-04 GO:0010467 gene expression
2.23 9.07e-04 GO:0050852 T cell receptor signaling pathway
1.76 9.64e-04 GO:0050867 positive regulation of cell activation
1.46 9.82e-04 GO:0007599 hemostasis
1.77 1.05e-03 GO:0002696 positive regulation of leukocyte activation
1.46 1.09e-03 GO:0007596 blood coagulation
1.46 1.09e-03 GO:0050817 coagulation
1.66 1.35e-03 GO:0002694 regulation of leukocyte activation
1.19 2.13e-03 GO:0048522 positive regulation of cellular process
1.94 2.40e-03 GO:0042110 T cell activation
1.34 2.52e-03 GO:0015031 protein transport
1.68 2.67e-03 GO:0051249 regulation of lymphocyte activation
1.41 2.91e-03 GO:0050878 regulation of body fluid levels
1.85 3.08e-03 GO:0050870 positive regulation of T cell activation
1.51 3.31e-03 GO:0051056 regulation of small GTPase mediated signal transduction
1.37 3.43e-03 GO:0002682 regulation of immune system process
1.23 4.04e-03 GO:0009059 macromolecule biosynthetic process
1.62 4.27e-03 GO:0050865 regulation of cell activation
1.35 4.59e-03 GO:0016192 vesicle-mediated transport
1.30 4.59e-03 GO:0006793 phosphorus metabolic process
1.30 4.59e-03 GO:0006796 phosphate metabolic process
1.32 4.82e-03 GO:0045184 establishment of protein localization
1.23 4.88e-03 GO:0034645 cellular macromolecule biosynthetic process
1.40 5.40e-03 GO:0006259 DNA metabolic process
1.33 5.90e-03 GO:0022402 cell cycle process
1.29 6.24e-03 GO:0008104 protein localization
1.09 8.74e-03 GO:0044238 primary metabolic process
1.55 1.22e-02 GO:0050778 positive regulation of immune response
1.47 1.68e-02 GO:0007264 small GTPase mediated signal transduction
1.28 1.70e-02 GO:0007049 cell cycle
1.22 1.88e-02 GO:0023051 regulation of signaling
1.37 1.96e-02 GO:0042060 wound healing
2.18 2.09e-02 GO:0030217 T cell differentiation
1.35 2.14e-02 GO:0007167 enzyme linked receptor protein signaling pathway
1.15 2.38e-02 GO:0034641 cellular nitrogen compound metabolic process
1.25 2.63e-02 GO:0044085 cellular component biogenesis
1.69 2.73e-02 GO:0050863 regulation of T cell activation
1.90 3.06e-02 GO:0050670 regulation of lymphocyte proliferation
1.72 3.81e-02 GO:0002697 regulation of immune effector process
1.87 3.87e-02 GO:0070663 regulation of leukocyte proliferation
1.88 4.13e-02 GO:0032944 regulation of mononuclear cell proliferation
1.44 4.62e-02 GO:0006886 intracellular protein transport
1.27 4.98e-02 GO:0032774 RNA biosynthetic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.09 1.48e-15 GO:0005622 intracellular
1.09 2.72e-13 GO:0044424 intracellular part
1.30 9.70e-11 GO:0044428 nuclear part
1.32 1.87e-10 GO:0031981 nuclear lumen
1.28 1.33e-08 GO:0005829 cytosol
1.35 1.37e-08 GO:0005654 nucleoplasm
1.15 1.39e-08 GO:0044446 intracellular organelle part
1.15 1.97e-08 GO:0005634 nucleus
1.14 3.29e-08 GO:0044422 organelle part
1.22 1.47e-07 GO:0043228 non-membrane-bounded organelle
1.22 1.47e-07 GO:0043232 intracellular non-membrane-bounded organelle
1.24 2.38e-07 GO:0043233 organelle lumen
1.08 2.89e-07 GO:0043226 organelle
1.08 3.24e-07 GO:0043229 intracellular organelle
1.24 3.97e-07 GO:0031974 membrane-enclosed lumen
1.24 4.30e-07 GO:0070013 intracellular organelle lumen
1.09 8.96e-07 GO:0005737 cytoplasm
1.17 8.76e-06 GO:0032991 macromolecular complex
1.08 1.51e-05 GO:0043227 membrane-bounded organelle
1.08 2.28e-05 GO:0043231 intracellular membrane-bounded organelle
1.03 1.90e-04 GO:0044464 cell part
1.03 2.02e-04 GO:0005623 cell
1.33 1.81e-03 GO:0044451 nucleoplasm part
1.15 1.91e-03 GO:0043234 protein complex
1.22 2.90e-03 GO:0005856 cytoskeleton
1.39 5.01e-03 GO:0005730 nucleolus
1.09 1.15e-02 GO:0044444 cytoplasmic part
1.61 1.48e-02 GO:0031252 cell leading edge
1.80 1.77e-02 GO:0030055 cell-substrate junction
1.82 2.23e-02 GO:0005925 focal adhesion
1.33 2.55e-02 GO:0005694 chromosome
1.34 2.84e-02 GO:0030529 ribonucleoprotein complex
1.78 3.51e-02 GO:0005924 cell-substrate adherens junction

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.16 2.29e-16 GO:0005515 protein binding
1.06 9.14e-07 GO:0005488 binding
1.49 4.09e-05 GO:0060589 nucleoside-triphosphatase regulator activity
1.49 6.27e-05 GO:0030695 GTPase regulator activity
1.82 2.35e-04 GO:0005085 guanyl-nucleotide exchange factor activity
1.50 9.76e-03 GO:0005083 small GTPase regulator activity
2.04 1.15e-02 GO:0005089 Rho guanyl-nucleotide exchange factor activity
1.88 2.45e-02 GO:0005088 Ras guanyl-nucleotide exchange factor activity
1.40 4.86e-02 GO:0000988 protein binding transcription factor activity
1.40 4.86e-02 GO:0000989 transcription factor binding transcription factor activity