Motif ID: GATA1..3.p2

Z-value: 2.454


Transcription factors associated with GATA1..3.p2:

Gene SymbolEntrez IDGene Name
GATA1 2623 GATA binding protein 1 (globin transcription factor 1)
GATA2 2624 GATA binding protein 2
GATA3 2625 GATA binding protein 3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
GATA3chr10_+_8136639-0.273.1e-01Click!
GATA1chrX_+_485299050.185.2e-01Click!
GATA2chr3_-_1296947170.107.1e-01Click!


Activity profile for motif GATA1..3.p2.

activity profile for motif GATA1..3.p2


Sorted Z-values histogram for motif GATA1..3.p2

Sorted Z-values for motif GATA1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GATA1..3.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr17_+_39990124 2.602 NM_001466
FZD2
frizzled homolog 2 (Drosophila)
chr6_-_74284522 2.401 EEF1A1
eukaryotic translation elongation factor 1 alpha 1
chr8_-_108579270 2.392 NM_001146
ANGPT1
angiopoietin 1
chr11_-_85107569 2.316 NM_206929
SYTL2
synaptotagmin-like 2
chr9_-_16717887 2.184 BNC2
basonuclin 2
chr15_+_41597097 2.128 NM_002373
MAP1A
microtubule-associated protein 1A
chr9_+_70161634 2.112 NM_021965
PGM5
phosphoglucomutase 5
chr6_-_119137923 2.038 NM_001178035
C6orf204
chromosome 6 open reading frame 204
chr1_-_85816520 1.880 NM_001134445
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr5_+_140871107 1.800


chr1_+_66772393 1.797 NM_032291
SGIP1
SH3-domain GRB2-like (endophilin) interacting protein 1
chr7_+_143263191 1.775 NM_001004685
OR2F2
olfactory receptor, family 2, subfamily F, member 2
chr2_-_189752575 1.753 NM_000393
COL5A2
collagen, type V, alpha 2
chr12_-_48902692 1.681 NM_001113547
LIMA1
LIM domain and actin binding 1
chr17_-_45629401 1.641


chr7_-_5534252 1.610 ACTB
actin, beta
chr5_+_140870881 1.583


chr5_-_141973875 1.564 NM_033137
FGF1
fibroblast growth factor 1 (acidic)
chr8_-_93099040 1.487 NM_175636
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr10_+_35524060 1.478 NM_182717
NM_182718
NM_182719
NM_182720
CREM



cAMP responsive element modulator




Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 85 entries
enrichment   p-value GO term description
1.96 8.60e-04 GO:0034728 nucleosome organization
1.95 4.30e-03 GO:0006334 nucleosome assembly
1.85 2.46e-02 GO:0031497 chromatin assembly
1.84 6.02e-04 GO:0006333 chromatin assembly or disassembly
1.83 9.83e-03 GO:0071824 protein-DNA complex subunit organization
1.81 2.50e-02 GO:0065004 protein-DNA complex assembly
1.48 1.25e-04 GO:0006325 chromatin organization
1.48 1.19e-02 GO:0007411 axon guidance
1.44 1.77e-04 GO:0051253 negative regulation of RNA metabolic process
1.43 5.50e-04 GO:0045892 negative regulation of transcription, DNA-dependent
1.43 1.09e-02 GO:0007409 axonogenesis
1.42 1.58e-04 GO:0010629 negative regulation of gene expression
1.42 1.12e-02 GO:0048667 cell morphogenesis involved in neuron differentiation
1.42 3.01e-02 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.40 4.48e-04 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.40 2.71e-02 GO:0007268 synaptic transmission
1.40 3.13e-02 GO:0032583 regulation of gene-specific transcription
1.39 1.01e-04 GO:0030182 neuron differentiation
1.39 7.42e-04 GO:0051172 negative regulation of nitrogen compound metabolic process
1.39 1.87e-03 GO:0048666 neuron development

Gene overrepresentation in compartment category:

Showing 1 to 9 of 9 entries
enrichment   p-value GO term description
2.13 1.86e-03 GO:0000786 nucleosome
1.56 2.19e-02 GO:0030424 axon
1.40 6.71e-03 GO:0043005 neuron projection
1.15 1.09e-05 GO:0032991 macromolecular complex
1.13 6.28e-03 GO:0043234 protein complex
1.09 2.55e-03 GO:0005634 nucleus
1.04 4.23e-02 GO:0044424 intracellular part
1.03 1.57e-04 GO:0044464 cell part
1.03 1.67e-04 GO:0005623 cell

Gene overrepresentation in function category:

Showing 1 to 12 of 12 entries
enrichment   p-value GO term description
3.09 3.03e-02 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity
1.55 2.17e-02 GO:0010843 promoter binding
1.53 2.87e-02 GO:0000975 regulatory region DNA binding
1.53 2.87e-02 GO:0001067 regulatory region nucleic acid binding
1.53 2.87e-02 GO:0044212 transcription regulatory region DNA binding
1.46 1.46e-02 GO:0008134 transcription factor binding
1.43 5.95e-07 GO:0043565 sequence-specific DNA binding
1.43 2.87e-02 GO:0016564 transcription repressor activity
1.36 1.37e-07 GO:0030528 transcription regulator activity
1.27 1.46e-03 GO:0001071 nucleic acid binding transcription factor activity
1.27 1.46e-03 GO:0003700 sequence-specific DNA binding transcription factor activity
1.10 4.77e-07 GO:0005515 protein binding