Motif ID: GATA6.p2

Z-value: 4.199


Transcription factors associated with GATA6.p2:

Gene SymbolEntrez IDGene Name
GATA6 2627 GATA binding protein 6

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
GATA6chr18_+_18003401-0.302.6e-01Click!


Activity profile for motif GATA6.p2.

activity profile for motif GATA6.p2


Sorted Z-values histogram for motif GATA6.p2

Sorted Z-values for motif GATA6.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GATA6.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_+_70745615 22.501 NM_033496
 HK1
hexokinase 1
chr7_-_100077072 19.613 NM_003227
 TFR2
transferrin receptor 2
chr12_-_52975823 15.622 NFE2
nuclear factor (erythroid-derived 2), 45kDa
chr12_-_52975777 15.473 NM_006163
 NFE2
nuclear factor (erythroid-derived 2), 45kDa
chr9_-_99740243 13.281 NM_197978
 HEMGN
hemogen
chr7_-_142369534 13.111 NM_000420
 KEL
Kell blood group, metallo-endopeptidase
chr7_-_142369519 12.823 KEL
Kell blood group, metallo-endopeptidase
chr11_+_118463906 10.504 NM_001024382
 HMBS
hydroxymethylbilane synthase
chr16_-_87570716 10.460 NM_005187
 CBFA2T3
core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr1_-_156923111 10.247 NM_003126
 SPTA1
spectrin, alpha, erythrocytic 1 (elliptocytosis 2)
chr6_-_49712483 10.206 NM_000324
 RHAG
Rh-associated glycoprotein
chr1_+_43063817 9.975 NM_018538
 ERMAP
erythroblast membrane-associated protein (Scianna blood group)
chr6_+_31782618 9.590 NM_001003693
 LY6G6F
lymphocyte antigen 6 complex, locus G6F
chrX_+_65152004 9.333


chr1_-_27113018 9.032 NM_021969
 NR0B2
nuclear receptor subfamily 0, group B, member 2
chr17_-_59437782 8.402 NM_000873
 ICAM2
intercellular adhesion molecule 2
chr1_+_181028016 8.136 NM_030769
 NPL
N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
chr19_-_12858956 8.039 NM_006563
 KLF1
Kruppel-like factor 1 (erythroid)
chr8_-_38127489 7.992 NM_000349
 STAR
steroidogenic acute regulatory protein
chr17_-_53764867 7.947



Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 34 entries
enrichment   p-value GO term description
12.46 3.08e-02 GO:0030299 intestinal cholesterol absorption
9.97 2.22e-02 GO:0044241 lipid digestion
9.38 1.26e-03 GO:0050892 intestinal absorption
8.21 1.95e-02 GO:0007597 blood coagulation, intrinsic pathway
7.98 5.71e-03 GO:0072378 blood coagulation, fibrin clot formation
6.45 9.44e-04 GO:0022600 digestive system process
4.88 3.27e-07 GO:0007586 digestion
3.94 9.24e-03 GO:0002576 platelet degranulation
3.15 5.79e-03 GO:0006805 xenobiotic metabolic process
3.15 5.79e-03 GO:0071466 cellular response to xenobiotic stimulus
3.13 6.54e-03 GO:0009410 response to xenobiotic stimulus
2.81 3.91e-04 GO:0008202 steroid metabolic process
2.71 1.38e-03 GO:0030168 platelet activation
2.60 7.72e-07 GO:0007608 sensory perception of smell
2.56 4.57e-02 GO:0003013 circulatory system process
2.56 4.57e-02 GO:0008015 blood circulation
2.46 1.74e-06 GO:0007606 sensory perception of chemical stimulus
2.19 3.27e-02 GO:0044057 regulation of system process
2.10 2.07e-03 GO:0001775 cell activation
2.03 5.80e-04 GO:0048878 chemical homeostasis

Gene overrepresentation in compartment category:

Showing 1 to 15 of 15 entries
enrichment   p-value GO term description
4.24 2.94e-02 GO:0031093 platelet alpha granule lumen
4.15 3.55e-02 GO:0034774 secretory granule lumen
4.13 8.03e-03 GO:0031091 platelet alpha granule
2.61 1.17e-02 GO:0016324 apical plasma membrane
2.46 7.04e-03 GO:0045177 apical part of cell
1.85 1.45e-04 GO:0005615 extracellular space
1.80 1.79e-05 GO:0044421 extracellular region part
1.71 3.65e-10 GO:0005576 extracellular region
1.47 6.53e-11 GO:0071944 cell periphery
1.46 1.81e-10 GO:0005886 plasma membrane
1.41 4.01e-03 GO:0044459 plasma membrane part
1.29 5.87e-06 GO:0031224 intrinsic to membrane
1.28 4.03e-05 GO:0016021 integral to membrane
1.26 8.62e-06 GO:0044425 membrane part
1.18 1.14e-03 GO:0016020 membrane

Gene overrepresentation in function category:

Showing 1 to 11 of 11 entries
enrichment   p-value GO term description
6.98 1.70e-02 GO:0001637 G-protein chemoattractant receptor activity
6.98 1.70e-02 GO:0004950 chemokine receptor activity
6.34 3.43e-02 GO:0019956 chemokine binding
2.73 3.50e-08 GO:0004984 olfactory receptor activity
2.15 7.92e-09 GO:0004930 G-protein coupled receptor activity
1.94 1.28e-09 GO:0004888 transmembrane receptor activity
1.91 3.05e-02 GO:0008289 lipid binding
1.81 4.33e-10 GO:0004872 receptor activity
1.63 1.44e-07 GO:0004871 signal transducer activity
1.63 1.44e-07 GO:0060089 molecular transducer activity
1.56 4.46e-02 GO:0005102 receptor binding