Motif ID: GFI1.p2

Z-value: 1.778


Transcription factors associated with GFI1.p2:

Gene SymbolEntrez IDGene Name
GFI1 2672 growth factor independent 1 transcription repressor

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
GFI1chr1_-_92725017-0.233.9e-01Click!


Activity profile for motif GFI1.p2.

activity profile for motif GFI1.p2


Sorted Z-values histogram for motif GFI1.p2

Sorted Z-values for motif GFI1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GFI1.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_183302105 4.175 ODZ3
odz, odd Oz/ten-m homolog 3 (Drosophila)
chr12_-_28016182 2.597 NM_002820
NM_198965
PTHLH

parathyroid hormone-like hormone

chr5_+_66160359 2.346 NM_015183
MAST4
microtubule associated serine/threonine kinase family member 4
chr11_-_127897098 2.290 ETS1
v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)
chr3_+_112876212 2.245 NM_001185106
NM_153268
PLCXD2

phosphatidylinositol-specific phospholipase C, X domain containing 2

chr3_+_173951163 2.209 ECT2
epithelial cell transforming sequence 2 oncogene
chr1_-_205272619 2.144 NM_001083924
NM_023938
C1orf116

chromosome 1 open reading frame 116

chr6_+_26333361 2.107 NM_003532
HIST1H3E
histone cluster 1, H3e
chr6_-_26379567 1.978 NM_003534
HIST1H3G
histone cluster 1, H3g
chr1_+_112740322 1.953 NM_018704
CTTNBP2NL
CTTNBP2 N-terminal like
chr1_+_112740378 1.926


chr6_+_26153590 1.907 NM_003531
HIST1H3C
histone cluster 1, H3c
chr8_-_41286088 1.889 NM_003012
SFRP1
secreted frizzled-related protein 1
chr21_-_42789369 1.886 NM_080860
RSPH1
radial spoke head 1 homolog (Chlamydomonas)
chr17_+_17816851 1.885 NM_001130090
NM_001130091
NM_001130092
NM_031294
LRRC48



leucine rich repeat containing 48



chr11_-_127897271 1.839 NM_001162422
NM_005238
ETS1

v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)

chr1_+_112740380 1.825 LOC100129406
CTTNBP2NL
hypothetical protein LOC100129406
CTTNBP2 N-terminal like
chr17_-_17816425 1.765 NM_001033551
NM_001082968
TOM1L2

target of myb1-like 2 (chicken)

chr6_-_30289092 1.718 NM_003449
TRIM26
tripartite motif containing 26
chr8_-_49996353 1.644 NM_003068
SNAI2
snail homolog 2 (Drosophila)
chr10_+_102782156 1.563 SFXN3
sideroflexin 3
chr8_+_102573837 1.431 NM_024915
GRHL2
grainyhead-like 2 (Drosophila)
chr17_-_67628523 1.426 FLJ37644
hypothetical LOC400618
chr17_+_67628749 1.418 NM_000346
SOX9
SRY (sex determining region Y)-box 9
chr1_-_93919789 1.409 NM_003567
BCAR3
breast cancer anti-estrogen resistance 3
chr17_+_67628772 1.387 SOX9
SRY (sex determining region Y)-box 9
chr8_+_102574012 1.361 GRHL2
grainyhead-like 2 (Drosophila)
chr4_+_38860418 1.356 NM_025132
WDR19
WD repeat domain 19
chr1_-_36688556 1.333 NM_145047
NM_206837
OSCP1

organic solute carrier partner 1

chr18_+_27281729 1.330 NM_001944
DSG3
desmoglein 3
chr19_-_11352850 1.325 EPOR
erythropoietin receptor
chr10_-_123346148 1.324 NM_001144915
FGFR2
fibroblast growth factor receptor 2
chr18_+_19706979 1.288 NM_000227
NM_001127718
LAMA3

laminin, alpha 3

chrX_+_56275510 1.276 NM_007250
NM_001159296
KLF8

Kruppel-like factor 8

chrX_+_17665483 1.273 NM_001037535
NM_001037536
NM_001037540
NM_006746
SCML1



sex comb on midleg-like 1 (Drosophila)



chr16_+_49333461 1.272 NM_001042355
NM_015247
CYLD

cylindromatosis (turban tumor syndrome)

chr10_+_102782151 1.271 SFXN3
sideroflexin 3
chr17_+_67628763 1.268 SOX9
SRY (sex determining region Y)-box 9
chr12_+_4300607 1.268 NM_020375
C12orf5
chromosome 12 open reading frame 5
chr10_-_101680645 1.266 DNMBP
dynamin binding protein
chr16_+_49333513 1.244 NM_001042412
CYLD
cylindromatosis (turban tumor syndrome)
chr4_+_47181987 1.244 NM_020453
ATP10D
ATPase, class V, type 10D
chr1_+_85300580 1.234 NM_145172
WDR63
WD repeat domain 63
chr6_-_10520264 1.214 TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr16_+_67236730 1.201 CDH3
cadherin 3, type 1, P-cadherin (placental)
chr5_+_3649167 1.195 NM_024337
IRX1
iroquois homeobox 1
chr4_-_115120251 1.193 NM_024590
ARSJ
arylsulfatase family, member J
chr16_+_67236699 1.182 CDH3
cadherin 3, type 1, P-cadherin (placental)
chr14_+_20580224 1.172 NM_032572
RNASE7
ribonuclease, RNase A family, 7
chr5_-_124108672 1.171 NM_020747
ZNF608
zinc finger protein 608
chr9_-_23816062 1.148 NM_004432
ELAVL2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr11_-_8849485 1.148 ST5
suppression of tumorigenicity 5
chr7_-_27162688 1.148 NM_006896
HOXA7
homeobox A7
chr11_+_13255836 1.132 NM_001030272
NM_001030273
NM_001178
ARNTL


aryl hydrocarbon receptor nuclear translocator-like


chr8_+_42129620 1.127 NM_001134296
NM_006803
AP3M2

adaptor-related protein complex 3, mu 2 subunit

chr18_-_43711143 1.117 SMAD2
SMAD family member 2
chr14_-_90596665 1.111 NM_004755
NM_182398
RPS6KA5

ribosomal protein S6 kinase, 90kDa, polypeptide 5

chr7_-_121571472 1.104 NM_005763
AASS
aminoadipate-semialdehyde synthase
chr11_-_117640407 1.096 NM_005797
NM_144765
MPZL2

myelin protein zero-like 2

chr15_+_83724743 1.090 NM_006738
NM_007200
AKAP13

A kinase (PRKA) anchor protein 13

chr4_+_77829634 1.089 SHROOM3
shroom family member 3
chr3_-_71196696 1.089 FOXP1
forkhead box P1
chr4_-_122063118 1.082 NM_018699
PRDM5
PR domain containing 5
chr19_+_45976001 1.078 NM_016154
RAB4B-EGLN2
RAB4B
RAB4B-EGLN2 read-through transcript
RAB4B, member RAS oncogene family
chr12_+_52733927 1.069 NM_153633
HOXC4
HOXC6
homeobox C4
homeobox C6
chr19_+_13767207 1.061 NM_023072
ZSWIM4
zinc finger, SWIM-type containing 4
chr9_-_34319151 1.058 NM_194313
KIF24
kinesin family member 24
chr4_+_120167264 1.058 SYNPO2
synaptopodin 2
chr11_-_72111027 1.034 NM_001135190
NM_015242
ARAP1

ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1

chr15_+_39032927 1.029 NM_001142776
NM_024111
CHAC1

ChaC, cation transport regulator homolog 1 (E. coli)

chr7_-_27153892 1.020 NM_024014
HOXA6
homeobox A6
chr12_-_45759691 1.019 NM_001143668
NM_181847
AMIGO2

adhesion molecule with Ig-like domain 2

chr9_+_130485754 1.012 NM_001122821
SET
SET nuclear oncogene
chr9_+_129605275 1.004 NM_001018078
FPGS
folylpolyglutamate synthase
chr6_-_26125939 1.000 NM_005325
HIST1H1A
histone cluster 1, H1a
chr18_+_45342398 0.997 NM_006033
LIPG
lipase, endothelial
chr2_+_98070026 0.990 NM_144992
VWA3B
von Willebrand factor A domain containing 3B
chr7_+_65307816 0.980 TPST1
tyrosylprotein sulfotransferase 1
chr9_+_115367122 0.979 NM_134427
RGS3
regulator of G-protein signaling 3
chr8_-_28403652 0.979 NM_172366
FBXO16
ZNF395
F-box protein 16
zinc finger protein 395
chr6_+_36752244 0.974 NM_078467
CDKN1A
cyclin-dependent kinase inhibitor 1A (p21, Cip1)
chr8_-_119192985 0.970 NM_000127
EXT1
exostosin 1
chr7_-_86686754 0.969 NM_024315
C7orf23
chromosome 7 open reading frame 23
chr19_-_1993022 0.968 MKNK2
MAP kinase interacting serine/threonine kinase 2
chr11_+_13255967 0.967 ARNTL
aryl hydrocarbon receptor nuclear translocator-like
chr4_-_76774594 0.965 NM_003948
CDKL2
cyclin-dependent kinase-like 2 (CDC2-related kinase)
chr9_+_130485926 0.962 SET
SET nuclear oncogene
chr9_+_34319503 0.949 NM_001161
NM_147172
NM_147173
NUDT2


nudix (nucleoside diphosphate linked moiety X)-type motif 2


chr3_-_87122958 0.947 VGLL3
vestigial like 3 (Drosophila)
chr5_+_142130154 0.944 ARHGAP26
Rho GTPase activating protein 26
chr9_+_129605349 0.937 FPGS
folylpolyglutamate synthase
chr11_+_13255905 0.937 ARNTL
aryl hydrocarbon receptor nuclear translocator-like
chr6_+_32970477 0.936 LOC100294145
hypothetical LOC100294145
chr4_+_167013859 0.936 NM_012464
TLL1
tolloid-like 1
chr10_-_123347493 0.927 NM_000141
NM_001144917
NM_001144918
NM_001144919
NM_022970
FGFR2




fibroblast growth factor receptor 2




chr15_-_81744469 0.915 NM_001717
BNC1
basonuclin 1
chr4_+_8251818 0.911 NM_018986
SH3TC1
SH3 domain and tetratricopeptide repeats 1
chr7_+_65307691 0.910 NM_003596
TPST1
tyrosylprotein sulfotransferase 1
chr4_+_77829743 0.905 SHROOM3
shroom family member 3
chr12_+_27568311 0.900 NM_001198915
NM_001198916
NM_003622
NM_177444
PPFIBP1



PTPRF interacting protein, binding protein 1 (liprin beta 1)



chr11_+_43658718 0.895 NM_016142
HSD17B12
hydroxysteroid (17-beta) dehydrogenase 12
chr9_-_98841186 0.894 NM_001333
CTSL2
cathepsin L2
chr6_+_26381122 0.891 NM_003525
HIST1H2BI
histone cluster 1, H2bi
chr9_+_129604962 0.885 NM_004957
FPGS
folylpolyglutamate synthase
chr17_+_56109940 0.882 NM_001099432
NM_017679
BCAS3

breast carcinoma amplified sequence 3

chr16_+_81218074 0.878 NM_001257
CDH13
cadherin 13, H-cadherin (heart)
chr5_-_73973004 0.872 NM_003633
ENC1
ectodermal-neural cortex 1 (with BTB-like domain)
chr3_-_116348780 0.871 NM_015642
ZBTB20
zinc finger and BTB domain containing 20
chr18_-_46978029 0.869 NM_016626
MEX3C
mex-3 homolog C (C. elegans)
chr1_-_20931288 0.868 SH2D5
SH2 domain containing 5
chr5_-_127901633 0.868 NM_001999
FBN2
fibrillin 2
chr11_+_13255925 0.865 ARNTL
aryl hydrocarbon receptor nuclear translocator-like
chrX_-_10548458 0.864 NM_000381
NM_033289
MID1

midline 1 (Opitz/BBB syndrome)

chr11_+_13255913 0.860 ARNTL
aryl hydrocarbon receptor nuclear translocator-like
chr5_+_174084137 0.858 NM_002449
MSX2
msh homeobox 2
chr1_-_68470585 0.857 NM_001002292
NM_001193334
NM_024911
WLS


wntless homolog (Drosophila)


chr11_-_58099884 0.851 NM_004811
LPXN
leupaxin
chr3_-_87122936 0.845 NM_016206
VGLL3
vestigial like 3 (Drosophila)
chr1_+_101474892 0.843 NM_001400
S1PR1
sphingosine-1-phosphate receptor 1
chr1_+_24518501 0.842 NM_001195010
GRHL3
grainyhead-like 3 (Drosophila)
chr7_-_42243318 0.839 GLI3
GLI family zinc finger 3
chr4_-_35922288 0.837 NM_015230
ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr19_+_45973139 0.833 NM_006533
MIA
melanoma inhibitory activity
chr14_+_105028614 0.831 NM_001134875
NM_001134876
C14orf80

chromosome 14 open reading frame 80

chr5_+_140835788 0.831 PCDHGC3
protocadherin gamma subfamily C, 3
chr4_-_151990061 0.828 LRBA
LPS-responsive vesicle trafficking, beach and anchor containing
chr3_-_173911467 0.825 NM_001146276
NM_001146277
NM_001146278
NM_020792
NCEH1



neutral cholesterol ester hydrolase 1



chr18_-_46977687 0.824 MEX3C
mex-3 homolog C (C. elegans)
chr3_+_115258348 0.821 QTRTD1
queuine tRNA-ribosyltransferase domain containing 1
chr6_+_21701942 0.815 NM_003107
SOX4
SRY (sex determining region Y)-box 4
chr5_+_142130475 0.813 NM_001135608
NM_015071
ARHGAP26

Rho GTPase activating protein 26

chr1_-_208046011 0.811 NM_006147
IRF6
interferon regulatory factor 6
chr20_+_54637714 0.799 NM_003222
TFAP2C
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
chrX_-_62891667 0.798 ARHGEF9
Cdc42 guanine nucleotide exchange factor (GEF) 9
chr6_+_26128656 0.797 NM_003529
HIST1H3A
histone cluster 1, H3a
chr11_+_13255952 0.790 ARNTL
aryl hydrocarbon receptor nuclear translocator-like
chr5_+_102229612 0.789 PAM
peptidylglycine alpha-amidating monooxygenase
chr22_-_26527469 0.787 NM_002430
MN1
meningioma (disrupted in balanced translocation) 1
chr3_-_48607596 0.786 NM_000094
COL7A1
collagen, type VII, alpha 1
chr2_+_74539039 0.781 NM_012477
WBP1
WW domain binding protein 1
chr9_+_91115924 0.780 NM_001827
CKS2
CDC28 protein kinase regulatory subunit 2
chr16_+_67328805 0.778 CDH1
cadherin 1, type 1, E-cadherin (epithelial)
chr6_+_30565161 0.775 NM_005516
HLA-E
major histocompatibility complex, class I, E
chr11_+_13255948 0.773 ARNTL
aryl hydrocarbon receptor nuclear translocator-like
chr19_+_18164989 0.773 NM_032683
MPV17L2
MPV17 mitochondrial membrane protein-like 2
chr14_+_73621408 0.769 NM_001024674
LIN52
lin-52 homolog (C. elegans)
chr6_+_114285209 0.764 NM_002356
MARCKS
myristoylated alanine-rich protein kinase C substrate
chr1_-_27212035 0.763 FAM46B
family with sequence similarity 46, member B
chr9_-_35062545 0.760 VCP
valosin containing protein
chr3_-_115960807 0.758 NM_001164344
NM_001164345
ZBTB20

zinc finger and BTB domain containing 20

chr5_+_140835727 0.757 NM_002588
NM_032402
NM_032403
PCDHGC3


protocadherin gamma subfamily C, 3


chr1_-_27211913 0.756 NM_052943
FAM46B
family with sequence similarity 46, member B
chr15_-_71712711 0.754 NM_001161363
NM_001161364
NM_012428
NM_017455
NPTN



neuroplastin



chr11_+_58631190 0.753 NM_001142703
NM_001142704
NM_198947
FAM111B


family with sequence similarity 111, member B


chr2_-_189752575 0.753 NM_000393
COL5A2
collagen, type V, alpha 2
chrX_-_62891730 0.753 NM_001173480
NM_015185
ARHGEF9

Cdc42 guanine nucleotide exchange factor (GEF) 9

chr5_+_102229425 0.746 NM_000919
NM_001177306
NM_138766
NM_138821
NM_138822
PAM




peptidylglycine alpha-amidating monooxygenase




chr7_-_42243142 0.745 NM_000168
GLI3
GLI family zinc finger 3
chr3_-_69517913 0.741 FRMD4B
FERM domain containing 4B
chr4_-_5761194 0.738 NM_147127
EVC2
Ellis van Creveld syndrome 2
chr1_+_218768423 0.733 MARK1
MAP/microtubule affinity-regulating kinase 1
chr6_+_46728590 0.727 NM_004277
SLC25A27
solute carrier family 25, member 27
chr6_-_166960649 0.721 RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr3_-_198948110 0.713 NM_014687
KIAA0226
KIAA0226
chrX_-_62891712 0.712 ARHGEF9
Cdc42 guanine nucleotide exchange factor (GEF) 9
chr18_+_42780784 0.709 NM_031303
KATNAL2
katanin p60 subunit A-like 2
chr15_-_97607108 0.708 NM_001040655
NM_001040656
NM_001040657
NM_001040658
NM_001040659
NM_001040660
NM_022905
TTC23






tetratricopeptide repeat domain 23






chr17_-_30783631 0.708 NM_018042
SLFN12
schlafen family member 12
chr5_-_112658200 0.704 MCC
mutated in colorectal cancers
chr4_+_155884564 0.694 LRAT
lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase)
chr3_-_109423858 0.694 NM_018010
IFT57
intraflagellar transport 57 homolog (Chlamydomonas)
chr5_-_112658456 0.692 NM_002387
MCC
mutated in colorectal cancers
chr5_-_54866126 0.690 NM_003711
NM_176895
RNF138P1
PPAP2A

ring finger protein 138 pseudogene 1
phosphatidic acid phosphatase type 2A

chr22_+_40107878 0.681 NM_003216
TEF
thyrotrophic embryonic factor
chr3_+_50248749 0.680 GNAI2
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
chr19_-_52709975 0.679 NAPA
N-ethylmaleimide-sensitive factor attachment protein, alpha
chr21_+_29439768 0.679 C21orf7
chromosome 21 open reading frame 7
chr4_+_155884600 0.677 NM_004744
LRAT
lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase)
chr1_+_101475149 0.677 S1PR1
sphingosine-1-phosphate receptor 1
chr6_-_10520592 0.676 NM_001032280
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chrX_-_131451675 0.675 NM_001170704
MBNL3
muscleblind-like 3 (Drosophila)
chr1_+_27062215 0.670 NM_006142
SFN
stratifin
chr9_+_123083540 0.670 GSN
gelsolin
chrX_-_103060777 0.668 LOC100128594
hypothetical LOC100128594
chr16_+_67328715 0.664 CDH1
cadherin 1, type 1, E-cadherin (epithelial)
chr2_-_85969527 0.663 NM_003896
ST3GAL5
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr16_-_78192111 0.662 NM_001031804
NM_005360
MAF

v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)

chr4_+_995395 0.661 FGFRL1
fibroblast growth factor receptor-like 1
chr1_-_95165037 0.661 CNN3
calponin 3, acidic
chr12_-_26877189 0.661 NM_002223
ITPR2
inositol 1,4,5-triphosphate receptor, type 2
chr14_+_75197409 0.660 TTLL5
tubulin tyrosine ligase-like family, member 5
chr16_+_67328693 0.659 NM_004360
CDH1
cadherin 1, type 1, E-cadherin (epithelial)
chr3_-_64186151 0.659 NM_198859
PRICKLE2
prickle homolog 2 (Drosophila)
chr1_-_150232927 0.658 S100A10
S100 calcium binding protein A10
chr19_-_63643400 0.658 NM_003433
ZNF132
zinc finger protein 132
chr17_+_19222319 0.654 NM_002749
NM_139034
MAPK7

mitogen-activated protein kinase 7

chr12_-_22378833 0.652 NM_003034
ST8SIA1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
chr16_+_67328737 0.640 CDH1
cadherin 1, type 1, E-cadherin (epithelial)
chr9_+_81376666 0.637 NM_007005
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chrX_-_47394937 0.635 NM_001114123
NM_005229
ELK1

ELK1, member of ETS oncogene family


Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.21 1.13e-07 GO:0005634 nucleus
1.10 7.09e-07 GO:0005622 intracellular
1.09 1.58e-05 GO:0044424 intracellular part
1.11 3.37e-05 GO:0043229 intracellular organelle
1.11 5.31e-05 GO:0043226 organelle
1.12 7.05e-05 GO:0043227 membrane-bounded organelle
1.12 7.15e-05 GO:0043231 intracellular membrane-bounded organelle

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.07 1.12e-02 GO:0005488 binding
1.11 3.00e-02 GO:0005515 protein binding