Motif ID: GLI1..3.p2

Z-value: 1.238


Transcription factors associated with GLI1..3.p2:

Gene SymbolEntrez IDGene Name
GLI1 2735 glioma-associated oncogene homolog 1 (zinc finger protein)
GLI2 2736 GLI-Kruppel family member GLI2
GLI3 2737 GLI-Kruppel family member GLI3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
GLI2chr2_+_1212713360.322.3e-01Click!
GLI3chr7_-_42243142-0.224.2e-01Click!
GLI1chr12_+_56140184-0.077.9e-01Click!


Activity profile for motif GLI1..3.p2.

activity profile for motif GLI1..3.p2


Sorted Z-values histogram for motif GLI1..3.p2

Sorted Z-values for motif GLI1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GLI1..3.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr16_+_48865521 1.036 ADCY7
adenylate cyclase 7
chr19_-_15436333 1.030 NM_022904
RASAL3
RAS protein activator like 3
chr11_-_60880799 0.970 NM_001161452
CYBASC3
cytochrome b, ascorbate dependent 3
chr12_-_3732614 0.900 NM_001144958
NM_001144959
NM_032680
EFCAB4B


EF-hand calcium binding domain 4B


chr12_+_110328126 0.880 NM_005475
SH2B3
SH2B adaptor protein 3
chr2_-_231498184 0.797 NM_005683
GPR55
G protein-coupled receptor 55
chr12_-_3732478 0.765 EFCAB4B
EF-hand calcium binding domain 4B
chr11_-_72057755 0.764 NM_001146209
PDE2A
phosphodiesterase 2A, cGMP-stimulated
chr1_-_209818675 0.759 NM_021194
SLC30A1
solute carrier family 30 (zinc transporter), member 1
chr19_+_3129735 0.734 NM_003775
S1PR4
sphingosine-1-phosphate receptor 4
chr1_+_148388719 0.681 NM_016274
PLEKHO1
pleckstrin homology domain containing, family O member 1
chr6_-_32892705 0.669 NM_002120
HLA-DOB
major histocompatibility complex, class II, DO beta
chr9_+_89302239 0.657 DAPK1
death-associated protein kinase 1
chr19_-_52307642 0.651


chr16_+_29581783 0.650 NM_001030288
SPN
sialophorin
chr1_-_209818576 0.645 SLC30A1
solute carrier family 30 (zinc transporter), member 1
chr22_-_49317408 0.617 ODF3B
outer dense fiber of sperm tails 3B
chr17_+_4795128 0.594 NM_001193503
NM_001976
NM_053013
ENO3


enolase 3 (beta, muscle)


chr16_+_66153810 0.594 NM_001191022
NM_006565
CTCF

CCCTC-binding factor (zinc finger protein)

chr5_-_156935283 0.585



Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
1.81 5.24e-05 GO:0016568 chromatin modification
1.65 5.92e-04 GO:0006325 chromatin organization
1.52 3.96e-03 GO:0051276 chromosome organization

Nothing significant found in compartment category.

Gene overrepresentation in function category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
1.89 4.14e-03 GO:0003682 chromatin binding
1.62 2.00e-02 GO:0016563 transcription activator activity
1.13 4.94e-05 GO:0005515 protein binding