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• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: GTF2I.p2

Z-value: 1.746

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr11_-_66897584	3.421	NM_013246	CLCF1	cardiotrophin-like cytokine factor 1
chr11_-_66898223	2.639	NM_001166212	CLCF1	cardiotrophin-like cytokine factor 1
chr2_-_227371698	2.506	NM_005544	IRS1	insulin receptor substrate 1
chr12_-_113606322	2.419	NM_005996 NM_016569	TBX3	T-box 3
chr9_+_108665168	2.010	NM_021224	ZNF462	zinc finger protein 462
chr15_+_41597097	1.817	NM_002373	MAP1A	microtubule-associated protein 1A
chr2_-_19421852	1.816	NM_145260	OSR1	odd-skipped related 1 (Drosophila)
chr11_-_56846246	1.730		TNKS1BP1	tankyrase 1 binding protein 1, 182kDa
chr16_+_84202515	1.728	NM_001134473	KIAA0182	KIAA0182
chr3_-_187025438	1.696		IGF2BP2	insulin-like growth factor 2 mRNA binding protein 2
chr9_+_138341752	1.638	NM_001145638 NM_015597	GPSM1	G-protein signaling modulator 1
chr19_-_36531958	1.540	NM_020856	TSHZ3	teashirt zinc finger homeobox 3
chr1_+_221955876	1.525	NM_001146068	CAPN2	calpain 2, (m/II) large subunit
chr11_+_12355600	1.509	NM_018222	PARVA	parvin, alpha
chr3_-_187025501	1.484	NM_001007225 NM_006548	IGF2BP2	insulin-like growth factor 2 mRNA binding protein 2
chr2_-_200030944	1.455	NM_001172509	SATB2	SATB homeobox 2
chr11_-_78829342	1.449	NM_001098816	ODZ4	odz, odd Oz/ten-m homolog 4 (Drosophila)
chr17_+_58058774	1.435		MRC2	mannose receptor, C type 2
chr6_+_1335067	1.403	NM_001452	FOXF2	forkhead box F2
chr12_-_24606616	1.401	NM_152989	SOX5	SRY (sex determining region Y)-box 5
chr18_+_44319365	1.387	NM_001142397 NM_014772	CTIF	CBP80/20-dependent translation initiation factor
chr12_+_6363482	1.341	NM_002342	LTBR	lymphotoxin beta receptor (TNFR superfamily, member 3)
chr2_-_144994038	1.325		ZEB2	zinc finger E-box binding homeobox 2
chr6_+_33495824	1.322	NM_006772	SYNGAP1	synaptic Ras GTPase activating protein 1
chr4_-_177950658	1.320	NM_005429	VEGFC	vascular endothelial growth factor C
chr1_-_68470585	1.287	NM_001002292 NM_001193334 NM_024911	WLS	wntless homolog (Drosophila)
chr17_-_7061641	1.275	NM_001128827	DLG4	discs, large homolog 4 (Drosophila)
chr1_-_20684858	1.246		CAMK2N1	calcium/calmodulin-dependent protein kinase II inhibitor 1
chr16_-_63713466	1.243		CDH11	cadherin 11, type 2, OB-cadherin (osteoblast)
chr17_+_58058783	1.241		MRC2	mannose receptor, C type 2
chr17_-_43977273	1.237	NM_002145	HOXB2	homeobox B2
chr16_-_63713485	1.236		CDH11	cadherin 11, type 2, OB-cadherin (osteoblast)
chr16_-_63713382	1.223	NM_001797	CDH11	cadherin 11, type 2, OB-cadherin (osteoblast)
chr8_+_22513043	1.207	NM_001013842 NM_001198827 NM_173686	C8orf58	chromosome 8 open reading frame 58
chr13_+_113574925	1.196	NM_001143945	GAS6	growth arrest-specific 6
chr2_+_200031333	1.191
chr12_+_46133	1.178	NM_001170738	IQSEC3	IQ motif and Sec7 domain 3
chr17_+_58058479	1.162	NM_006039	MRC2	mannose receptor, C type 2
chr5_+_148766632	1.150		LOC728264	hypothetical LOC728264
chr1_-_29322993	1.143	NM_001003682	TMEM200B	transmembrane protein 200B
chr14_-_60260211	1.125	NM_017420	SIX4	SIX homeobox 4
chr19_+_60691733	1.120		SSC5D	scavenger receptor cysteine rich domain containing (5 domains)
chr11_-_122571046	1.105		CLMP	CXADR-like membrane protein
chr12_+_92488932	1.103		SOCS2	suppressor of cytokine signaling 2
chr17_+_7682355	1.095
chr1_+_168898898	1.087		PRRX1	paired related homeobox 1
chr11_-_122571198	1.087	NM_024769	CLMP	CXADR-like membrane protein
chr1_-_72521079	1.083
chr1_-_27802688	1.081	NM_001029882	AHDC1	AT hook, DNA binding motif, containing 1
chr19_-_60573552	1.055	NM_000641	IL11	interleukin 11
chr2_-_144994349	1.026	NM_001171653 NM_014795	ZEB2	zinc finger E-box binding homeobox 2
chr22_-_34754343	1.024	NM_001082578 NM_001082579	RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2
chr1_-_20685314	1.013	NM_018584	CAMK2N1	calcium/calmodulin-dependent protein kinase II inhibitor 1
chr12_+_47495567	0.985		CACNB3	calcium channel, voltage-dependent, beta 3 subunit
chr1_-_32940943	0.943	NM_001161708 NM_030786	SYNC	syncoilin, intermediate filament protein
chr1_+_85819004	0.928	NM_001554	CYR61	cysteine-rich, angiogenic inducer, 61
chr1_+_199884152	0.914		NAV1	neuron navigator 1
chrX_+_73557809	0.912	NM_006517	SLC16A2	solute carrier family 16, member 2 (monocarboxylic acid transporter 8)
chr8_-_122722674	0.906	NM_005328	HAS2	hyaluronan synthase 2
chr16_+_56219802	0.904	NM_001145771 NM_001145772 NM_001145773 NM_201524 NM_201525	GPR56	G protein-coupled receptor 56
chr2_-_144991556	0.886		ZEB2	zinc finger E-box binding homeobox 2
chr19_-_54557450	0.871	NM_003598	TEAD2	TEA domain family member 2
chr1_+_162795538	0.859		PBX1	pre-B-cell leukemia homeobox 1
chr8_+_22078817	0.848		BMP1	bone morphogenetic protein 1
chr14_-_60260780	0.845		SIX4	SIX homeobox 4
chr22_-_28972683	0.842	NM_002309	LIF	leukemia inhibitory factor (cholinergic differentiation factor)
chr7_+_93862137	0.841		COL1A2 PLAG1	collagen, type I, alpha 2 pleiomorphic adenoma gene 1
chr21_-_27139563	0.840	NM_006988	ADAMTS1	ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr8_+_22078622	0.839		BMP1	bone morphogenetic protein 1
chr8_-_116750427	0.839		TRPS1	trichorhinophalangeal syndrome I
chr9_+_101623957	0.838	NM_006981 NM_173199	NR4A3	nuclear receptor subfamily 4, group A, member 3
chr7_-_150283794	0.831	NM_172057	KCNH2	potassium voltage-gated channel, subfamily H (eag-related), member 2
chr12_-_52179462	0.827	NM_001193511 NM_006301	MAP3K12	mitogen-activated protein kinase kinase kinase 12
chr17_-_44058612	0.824	NM_024017	HOXB9	homeobox B9
chr9_-_16860719	0.824	NM_017637	BNC2	basonuclin 2
chr1_-_32940850	0.820		SYNC	syncoilin, intermediate filament protein
chr3_-_121652183	0.804	NM_007085	FSTL1	follistatin-like 1
chr2_+_27046952	0.804	NM_012326	MAPRE3	microtubule-associated protein, RP/EB family, member 3
chr2_-_200030412	0.801		SATB2	SATB homeobox 2
chr1_+_201862845	0.795		ATP2B4	ATPase, Ca++ transporting, plasma membrane 4
chr1_-_212791597	0.793	NM_005401	PTPN14	protein tyrosine phosphatase, non-receptor type 14
chr10_+_88506320	0.789	NM_004329	BMPR1A	bone morphogenetic protein receptor, type IA
chr8_-_145090045	0.789	NM_201382	PLEC	plectin
chr12_+_8958397	0.782	NM_004426	PHC1	polyhomeotic homolog 1 (Drosophila)
chr2_-_218575922	0.778		TNS1	tensin 1
chr1_+_199884072	0.772	NM_020443	NAV1	neuron navigator 1
chr21_-_27139143	0.771		ADAMTS1	ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr12_+_55201854	0.769	NM_002898	RBMS2	RNA binding motif, single stranded interacting protein 2
chr12_-_92489652	0.767		LOC144481	hypothetical protein LOC144481
chr9_-_112381593	0.761	NM_153366	SVEP1	sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
chr8_-_9045548	0.754	NM_024607	PPP1R3B	protein phosphatase 1, regulatory (inhibitor) subunit 3B
chr22_-_34566210	0.753		RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2
chr19_+_60691671	0.751	NM_001144950 NM_001195267	SSC5D	scavenger receptor cysteine rich domain containing (5 domains)
chr1_-_212791467	0.746		PTPN14	protein tyrosine phosphatase, non-receptor type 14
chr22_-_34566276	0.746		RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2
chr6_+_149109841	0.745	NM_005715	UST	uronyl-2-sulfotransferase
chr6_-_75972473	0.744		COL12A1	collagen, type XII, alpha 1
chr11_+_129823667	0.737	NM_139055	ADAMTS15	ADAM metallopeptidase with thrombospondin type 1 motif, 15
chr5_-_178704934	0.736		ADAMTS2	ADAM metallopeptidase with thrombospondin type 1 motif, 2
chr8_-_93184629	0.736	NM_001198633 NM_175634	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr6_+_108988761	0.736	NM_001455	FOXO3	forkhead box O3
chr1_+_156229934	0.735		KIRREL	kin of IRRE like (Drosophila)
chr20_-_61755145	0.723	NM_015894	STMN3	stathmin-like 3
chr1_+_162795328	0.720	NM_002585	PBX1	pre-B-cell leukemia homeobox 1
chr6_-_153494076	0.719	NM_012419	RGS17	regulator of G-protein signaling 17
chr3_+_189354167	0.718	NM_001167672	LPP	LIM domain containing preferred translocation partner in lipoma
chr8_-_116750277	0.718	NM_014112	TRPS1	trichorhinophalangeal syndrome I
chr7_-_5429702	0.711	NM_001080495	TNRC18	trinucleotide repeat containing 18
chr4_-_140696740	0.711	NM_030648	SETD7	SET domain containing (lysine methyltransferase) 7
chr7_-_112513379	0.707	NM_001146266 NM_001146267	GPR85	G protein-coupled receptor 85
chr1_+_168899936	0.704	NM_006902 NM_022716	PRRX1	paired related homeobox 1
chr7_-_139987044	0.700		DENND2A	DENN/MADD domain containing 2A
chr7_+_93861808	0.697	NM_000089	COL1A2	collagen, type I, alpha 2
chr9_+_35528890	0.694		RUSC2	RUN and SH3 domain containing 2
chr20_+_43468617	0.689	NM_001048223 NM_001048224	DBNDD2	dysbindin (dystrobrevin binding protein 1) domain containing 2
chr22_-_19180075	0.678	NM_032775	KLHL22	kelch-like 22 (Drosophila)
chr1_-_212791188	0.678		PTPN14	protein tyrosine phosphatase, non-receptor type 14
chr7_+_105304445	0.677		LOC100506768 CDHR3	hypothetical LOC100506768 cadherin-related family member 3
chr17_-_55824359	0.671	NM_032582	USP32	ubiquitin specific peptidase 32
chr16_+_85101605	0.667	NM_001451	FOXF1	forkhead box F1
chr11_-_8849485	0.667		ST5	suppression of tumorigenicity 5
chr2_+_220033777	0.663	NM_001173476	SPEG	SPEG complex locus
chr14_+_20608179	0.661	NM_018071	ARHGEF40	Rho guanine nucleotide exchange factor (GEF) 40
chr6_-_42527760	0.659	NM_033502	TRERF1	transcriptional regulating factor 1
chr1_-_150232900	0.648		S100A10	S100 calcium binding protein A10
chr19_-_242168	0.647	NM_177543	PPAP2C	phosphatidic acid phosphatase type 2C
chr18_+_3439972	0.643	NM_173209 NM_173208 NM_003244	TGIF1	TGFB-induced factor homeobox 1
chr10_+_114699953	0.642	NM_001146274 NM_001146283 NM_001146284 NM_001146285 NM_001146286 NM_001198525 NM_001198526 NM_001198527 NM_001198528 NM_001198529 NM_001198530 NM_001198531 NM_030756	TCF7L2	transcription factor 7-like 2 (T-cell specific, HMG-box)
chr14_-_60185659	0.640	NM_005982	SIX1	SIX homeobox 1
chr6_-_35572694	0.640	NM_003214	TEAD3	TEA domain family member 3
chr15_+_90197884	0.639	NM_001145044 NM_013272	SLCO3A1	solute carrier organic anion transporter family, member 3A1
chr12_-_51912101	0.637	NM_000966	RARG	retinoic acid receptor, gamma
chr9_-_16860664	0.637		BNC2	basonuclin 2
chr19_-_53950458	0.637	NM_000148	FUT1	fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
chr6_+_45498354	0.633		RUNX2	runt-related transcription factor 2
chr6_-_10520592	0.631	NM_001032280	TFAP2A	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr9_+_129414287	0.627	NM_001032221 NM_003165	STXBP1	syntaxin binding protein 1
chr1_-_150233337	0.626	NM_002966	S100A10	S100 calcium binding protein A10
chr16_+_85101734	0.618		FOXF1	forkhead box F1
chr9_+_35528628	0.616	NM_001135999	RUSC2	RUN and SH3 domain containing 2
chr9_+_124177421	0.615		PTGS1	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr5_-_38881636	0.611
chr1_-_72520735	0.609	NM_173808	NEGR1	neuronal growth regulator 1
chr12_+_51777715	0.609		IGFBP6	insulin-like growth factor binding protein 6
chr12_+_47494882	0.608		CACNB3	calcium channel, voltage-dependent, beta 3 subunit
chr18_-_21184824	0.607
chr7_-_105304159	0.606	NM_020725 NM_152749	ATXN7L1	ataxin 7-like 1
chr2_-_158440587	0.603	NM_001111067	ACVR1	activin A receptor, type I
chr14_+_23907065	0.602	NM_001198965 NM_004554	NFATC4	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
chr1_-_27802947	0.593		AHDC1	AT hook, DNA binding motif, containing 1
chr1_+_144183811	0.590		ANKRD34A	ankyrin repeat domain 34A
chr5_+_38881716	0.588	NM_001168355	OSMR	oncostatin M receptor
chr10_-_126839546	0.588	NM_001083914	CTBP2	C-terminal binding protein 2
chr3_+_77171938	0.584	NM_002942	ROBO2	roundabout, axon guidance receptor, homolog 2 (Drosophila)
chr4_-_140317686	0.580		ELF2	E74-like factor 2 (ets domain transcription factor)
chr2_+_182464910	0.580		SSFA2	sperm specific antigen 2
chr10_+_20145350	0.580	NM_032812	PLXDC2	plexin domain containing 2
chr12_-_21818881	0.579	NM_004982	KCNJ8	potassium inwardly-rectifying channel, subfamily J, member 8
chr9_+_117955890	0.576	NM_002581	PAPPA	pregnancy-associated plasma protein A, pappalysin 1
chr14_+_74815233	0.576	NM_005252	FOS	FBJ murine osteosarcoma viral oncogene homolog
chr7_+_33911636	0.574	NM_133468	BMPER	BMP binding endothelial regulator
chr5_-_146813343	0.573	NM_001387	DPYSL3	dihydropyrimidinase-like 3
chr12_+_54423330	0.573	NM_005811	GDF11	growth differentiation factor 11
chr14_+_31615922	0.572		ARHGAP5	Rho GTPase activating protein 5
chr5_+_135392482	0.564	NM_000358	TGFBI	transforming growth factor, beta-induced, 68kDa
chr13_+_99431417	0.563
chr5_+_38881719	0.561	NM_003999	OSMR	oncostatin M receptor
chr4_-_16509126	0.561		LDB2	LIM domain binding 2
chr1_+_28458546	0.560	NM_031459	SESN2	sestrin 2
chr16_+_68516401	0.559	NM_199424	WWP2	WW domain containing E3 ubiquitin protein ligase 2
chr8_-_82916982	0.553	NM_022133 NM_152836 NM_152837	SNX16	sorting nexin 16
chr5_-_64813459	0.550	NM_197941	ADAMTS6	ADAM metallopeptidase with thrombospondin type 1 motif, 6
chr12_+_51777684	0.549	NM_002178	IGFBP6	insulin-like growth factor binding protein 6
chr7_+_150390566	0.547		SLC4A2	solute carrier family 4, anion exchanger, member 2 (erythrocyte membrane protein band 3-like 1)
chr10_-_33663777	0.544	NM_001024628 NM_001024629 NM_003873	NRP1	neuropilin 1
chr12_+_52696908	0.543	NM_014620 NM_153693	HOXC4 HOXC6	homeobox C4 homeobox C6
chr19_-_56178882	0.543	NM_139277 NM_005046	KLK7	kallikrein-related peptidase 7
chr18_-_51406359	0.541		TCF4	transcription factor 4
chr10_-_126839056	0.538	NM_001329	CTBP2	C-terminal binding protein 2
chr1_-_68071635	0.535	NM_018841	GNG12	guanine nucleotide binding protein (G protein), gamma 12
chr4_+_184257337	0.533	NM_024949	WWC2	WW and C2 domain containing 2
chr19_-_242335	0.533	NM_003712 NM_177526	PPAP2C	phosphatidic acid phosphatase type 2C
chr2_+_188864975	0.530		GULP1	GULP, engulfment adaptor PTB domain containing 1
chr1_+_148747208	0.529		ECM1	extracellular matrix protein 1
chr5_+_38882017	0.528		OSMR	oncostatin M receptor
chr7_+_90731671	0.526	NM_003505	FZD1	frizzled homolog 1 (Drosophila)
chr6_+_108987703	0.525	NM_201559	FOXO3	forkhead box O3
chr7_-_27120015	0.523		HOXA3	homeobox A3
chr22_-_34566367	0.519	NM_001031695 NM_001082576 NM_001082577 NM_014309	RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2
chr2_+_27154938	0.519	NM_007046	EMILIN1	elastin microfibril interfacer 1
chr5_-_72780107	0.515	NM_004472	FOXD1	forkhead box D1
chr15_-_58477407	0.514	NM_001002857 NM_001002858 NM_001136015 NM_004039	ANXA2	annexin A2
chr1_-_225572419	0.514	NM_003607 NM_014826	CDC42BPA	CDC42 binding protein kinase alpha (DMPK-like)
chr19_-_51608665	0.511	NM_032040	CCDC8	coiled-coil domain containing 8
chr1_+_156229686	0.511	NM_018240	KIRREL	kin of IRRE like (Drosophila)
chr17_-_55824083	0.509		USP32	ubiquitin specific peptidase 32
chr10_-_62373828	0.508	NM_014836	RHOBTB1	Rho-related BTB domain containing 1
chr1_-_1465602	0.504	NM_001114748	C1orf70	chromosome 1 open reading frame 70
chr2_-_144991386	0.503		ZEB2	zinc finger E-box binding homeobox 2
chr12_+_51728999	0.501	NM_015319	TENC1	tensin like C1 domain containing phosphatase (tensin 2)

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.18	3.82e-28	GO:0050794	regulation of cellular process
1.17	4.51e-27	GO:0050789	regulation of biological process
1.15	1.39e-24	GO:0065007	biological regulation
1.24	9.48e-21	GO:0032502	developmental process
1.42	1.40e-20	GO:0007399	nervous system development
1.42	1.78e-20	GO:0009653	anatomical structure morphogenesis
1.26	2.41e-20	GO:0007275	multicellular organismal development
1.29	2.58e-20	GO:0048731	system development
1.26	1.44e-18	GO:0048856	anatomical structure development
1.23	1.08e-17	GO:0023052	signaling
1.49	1.31e-16	GO:0022008	neurogenesis
1.26	6.81e-16	GO:0048518	positive regulation of biological process
1.48	1.05e-14	GO:0048699	generation of neurons
1.22	2.13e-14	GO:0007165	signal transduction
1.29	2.27e-13	GO:0030154	cell differentiation
1.28	2.64e-13	GO:0048523	negative regulation of cellular process
1.28	4.74e-13	GO:0048869	cellular developmental process
1.26	1.71e-12	GO:0048519	negative regulation of biological process
1.25	1.84e-12	GO:0048522	positive regulation of cellular process
1.59	2.26e-12	GO:0000904	cell morphogenesis involved in differentiation
1.54	3.07e-12	GO:0000902	cell morphogenesis
1.52	3.98e-12	GO:0032989	cellular component morphogenesis
1.62	8.68e-12	GO:0048812	neuron projection morphogenesis
1.18	1.94e-11	GO:0051716	cellular response to stimulus
1.56	7.46e-11	GO:0048858	cell projection morphogenesis
1.41	7.72e-11	GO:0048468	cell development
1.61	8.34e-11	GO:0007409	axonogenesis
1.47	9.25e-11	GO:0030182	neuron differentiation
1.55	1.11e-10	GO:0032990	cell part morphogenesis
1.56	1.13e-10	GO:0031175	neuron projection development
1.59	1.20e-10	GO:0048667	cell morphogenesis involved in neuron differentiation
1.48	2.37e-10	GO:0030030	cell projection organization
1.29	3.95e-10	GO:0023051	regulation of signaling
1.51	4.49e-10	GO:0048666	neuron development
1.07	1.09e-09	GO:0009987	cellular process
1.31	1.27e-09	GO:0009966	regulation of signal transduction
1.25	7.12e-09	GO:0048513	organ development
1.37	1.89e-08	GO:0050793	regulation of developmental process
1.39	2.44e-08	GO:0051128	regulation of cellular component organization
1.18	2.80e-08	GO:0016043	cellular component organization
1.62	4.52e-08	GO:0001501	skeletal system development
1.24	5.25e-08	GO:0048583	regulation of response to stimulus
1.17	5.57e-08	GO:0071840	cellular component organization or biogenesis
1.30	9.33e-08	GO:0009893	positive regulation of metabolic process
1.31	1.17e-07	GO:0010604	positive regulation of macromolecule metabolic process
1.41	2.19e-07	GO:0045595	regulation of cell differentiation
1.32	4.22e-07	GO:0010646	regulation of cell communication
1.16	5.66e-07	GO:0060255	regulation of macromolecule metabolic process
1.38	6.39e-07	GO:2000026	regulation of multicellular organismal development
1.16	7.91e-07	GO:0080090	regulation of primary metabolic process
1.16	8.24e-07	GO:0031323	regulation of cellular metabolic process
1.29	9.09e-07	GO:0031325	positive regulation of cellular metabolic process
1.42	1.16e-06	GO:0009887	organ morphogenesis
1.28	1.45e-06	GO:0051239	regulation of multicellular organismal process
1.38	1.64e-06	GO:0009790	embryo development
1.56	1.72e-06	GO:0007411	axon guidance
1.57	1.72e-06	GO:0060284	regulation of cell development
1.44	3.38e-06	GO:0007417	central nervous system development
1.59	5.26e-06	GO:0061061	muscle structure development
1.29	5.63e-06	GO:0051246	regulation of protein metabolic process
1.37	7.64e-06	GO:0010628	positive regulation of gene expression
1.30	8.63e-06	GO:0032268	regulation of cellular protein metabolic process
1.38	1.16e-05	GO:0007167	enzyme linked receptor protein signaling pathway
1.30	1.25e-05	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.49	3.33e-05	GO:0007420	brain development
1.13	4.11e-05	GO:0019222	regulation of metabolic process
1.47	6.80e-05	GO:0009792	embryo development ending in birth or egg hatching
1.31	7.10e-05	GO:0009888	tissue development
1.20	1.07e-04	GO:0007166	cell surface receptor linked signaling pathway
1.11	1.19e-04	GO:0032501	multicellular organismal process
1.16	1.32e-04	GO:0071842	cellular component organization at cellular level
1.44	1.32e-04	GO:0009968	negative regulation of signal transduction
1.46	1.77e-04	GO:0043009	chordate embryonic development
1.28	1.78e-04	GO:0032879	regulation of localization
1.42	1.88e-04	GO:0023057	negative regulation of signaling
1.36	2.13e-04	GO:0010629	negative regulation of gene expression
1.57	2.30e-04	GO:0048568	embryonic organ development
1.42	2.32e-04	GO:0010648	negative regulation of cell communication
1.35	3.05e-04	GO:0045893	positive regulation of transcription, DNA-dependent
1.31	3.10e-04	GO:0051173	positive regulation of nitrogen compound metabolic process
1.45	3.29e-04	GO:0048598	embryonic morphogenesis
2.01	3.39e-04	GO:0022612	gland morphogenesis
1.38	3.43e-04	GO:0006935	chemotaxis
1.38	3.43e-04	GO:0042330	taxis
1.28	3.59e-04	GO:0010605	negative regulation of macromolecule metabolic process
1.15	3.84e-04	GO:0071841	cellular component organization or biogenesis at cellular level
1.30	3.86e-04	GO:0031399	regulation of protein modification process
1.39	5.04e-04	GO:0072358	cardiovascular system development
1.39	5.04e-04	GO:0072359	circulatory system development
1.36	5.53e-04	GO:0051253	negative regulation of RNA metabolic process
1.50	5.73e-04	GO:0001944	vasculature development
1.38	6.00e-04	GO:0048585	negative regulation of response to stimulus
1.31	6.08e-04	GO:0010557	positive regulation of macromolecule biosynthetic process
1.49	6.22e-04	GO:0051130	positive regulation of cellular component organization
1.32	6.36e-04	GO:0031327	negative regulation of cellular biosynthetic process
1.22	6.66e-04	GO:0035556	intracellular signal transduction
2.00	6.90e-04	GO:2000027	regulation of organ morphogenesis
1.37	6.92e-04	GO:0045892	negative regulation of transcription, DNA-dependent
1.48	7.28e-04	GO:0022603	regulation of anatomical structure morphogenesis
1.32	8.11e-04	GO:0009890	negative regulation of biosynthetic process
1.32	9.38e-04	GO:0051254	positive regulation of RNA metabolic process
2.59	9.94e-04	GO:0060688	regulation of morphogenesis of a branching structure
1.30	1.00e-03	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.38	1.04e-03	GO:0045944	positive regulation of transcription from RNA polymerase II promoter
1.33	1.08e-03	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
1.32	1.13e-03	GO:0010558	negative regulation of macromolecule biosynthetic process
1.26	1.62e-03	GO:0009892	negative regulation of metabolic process
2.08	1.63e-03	GO:0090101	negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
1.54	1.71e-03	GO:0002009	morphogenesis of an epithelium
1.71	1.83e-03	GO:0048705	skeletal system morphogenesis
1.57	1.95e-03	GO:0044087	regulation of cellular component biogenesis
1.32	2.14e-03	GO:0001932	regulation of protein phosphorylation
1.36	2.22e-03	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
1.31	2.34e-03	GO:0009719	response to endogenous stimulus
1.25	2.48e-03	GO:0007154	cell communication
1.27	2.58e-03	GO:0040011	locomotion
1.66	2.72e-03	GO:0034330	cell junction organization
1.34	3.06e-03	GO:0023056	positive regulation of signaling
1.26	3.22e-03	GO:0031324	negative regulation of cellular metabolic process
1.48	3.26e-03	GO:0035295	tube development
1.48	3.26e-03	GO:0051960	regulation of nervous system development
1.44	3.57e-03	GO:0051093	negative regulation of developmental process
1.51	3.60e-03	GO:0050767	regulation of neurogenesis
1.30	4.05e-03	GO:0019220	regulation of phosphate metabolic process
1.30	4.05e-03	GO:0051174	regulation of phosphorus metabolic process
1.46	4.05e-03	GO:0040012	regulation of locomotion
1.72	4.38e-03	GO:0090092	regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
1.57	4.64e-03	GO:0048732	gland development
1.34	4.81e-03	GO:0010647	positive regulation of cell communication
1.24	4.91e-03	GO:0009605	response to external stimulus
1.48	5.42e-03	GO:0045596	negative regulation of cell differentiation
1.26	5.43e-03	GO:0009891	positive regulation of biosynthetic process
1.14	5.57e-03	GO:0010468	regulation of gene expression
1.30	5.63e-03	GO:0042325	regulation of phosphorylation
1.45	6.22e-03	GO:0048729	tissue morphogenesis
1.26	6.74e-03	GO:0031328	positive regulation of cellular biosynthetic process
1.28	7.78e-03	GO:0016192	vesicle-mediated transport
1.34	8.72e-03	GO:0009967	positive regulation of signal transduction
1.39	9.22e-03	GO:0007264	small GTPase mediated signal transduction
1.66	9.33e-03	GO:0034329	cell junction assembly
1.31	9.60e-03	GO:0009725	response to hormone stimulus
1.14	9.83e-03	GO:0031326	regulation of cellular biosynthetic process
1.15	9.84e-03	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.35	1.00e-02	GO:0048646	anatomical structure formation involved in morphogenesis
1.30	1.10e-02	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.14	1.15e-02	GO:0010556	regulation of macromolecule biosynthetic process
1.30	1.32e-02	GO:0051172	negative regulation of nitrogen compound metabolic process
1.46	1.39e-02	GO:0001568	blood vessel development
1.13	1.42e-02	GO:0009889	regulation of biosynthetic process
1.59	1.61e-02	GO:0048562	embryonic organ morphogenesis
1.20	1.63e-02	GO:0051641	cellular localization
1.56	1.86e-02	GO:0030900	forebrain development
1.52	2.22e-02	GO:0007517	muscle organ development
1.26	2.53e-02	GO:0007267	cell-cell signaling
1.15	2.64e-02	GO:0065008	regulation of biological quality
1.39	3.11e-02	GO:0007389	pattern specification process
1.34	3.21e-02	GO:0051094	positive regulation of developmental process
1.44	3.34e-02	GO:0030334	regulation of cell migration
1.44	3.55e-02	GO:2000145	regulation of cell motility
1.56	3.94e-02	GO:0006813	potassium ion transport
1.13	3.95e-02	GO:0051171	regulation of nitrogen compound metabolic process
1.10	4.03e-02	GO:0044260	cellular macromolecule metabolic process
1.22	4.23e-02	GO:0042127	regulation of cell proliferation
1.13	4.55e-02	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.50	1.42e-11	GO:0030054	cell junction
1.21	2.73e-08	GO:0044459	plasma membrane part
1.73	3.76e-07	GO:0031252	cell leading edge
1.08	1.39e-06	GO:0005737	cytoplasm
1.52	9.26e-06	GO:0015629	actin cytoskeleton
1.44	1.36e-05	GO:0045202	synapse
1.43	2.32e-05	GO:0043005	neuron projection
1.29	4.03e-05	GO:0042995	cell projection
1.68	8.20e-05	GO:0005912	adherens junction
1.42	1.07e-04	GO:0031012	extracellular matrix
1.25	2.30e-04	GO:0005794	Golgi apparatus
1.62	2.61e-04	GO:0070161	anchoring junction
1.19	3.45e-04	GO:0005856	cytoskeleton
1.05	3.48e-04	GO:0044424	intracellular part
1.04	4.63e-04	GO:0005622	intracellular
1.16	5.53e-04	GO:0005829	cytosol
1.74	7.35e-04	GO:0030055	cell-substrate junction
1.77	9.80e-04	GO:0005925	focal adhesion
1.30	1.67e-03	GO:0044431	Golgi apparatus part
1.78	2.31e-03	GO:0001726	ruffle
1.71	2.69e-03	GO:0005924	cell-substrate adherens junction
1.38	6.18e-03	GO:0044433	cytoplasmic vesicle part
1.51	8.36e-03	GO:0030424	axon
1.44	1.03e-02	GO:0016323	basolateral plasma membrane
1.23	1.10e-02	GO:0031982	vesicle
1.85	1.12e-02	GO:0031256	leading edge membrane
1.11	1.35e-02	GO:0043234	protein complex
1.37	1.35e-02	GO:0005578	proteinaceous extracellular matrix
1.23	2.12e-02	GO:0031410	cytoplasmic vesicle
1.47	2.23e-02	GO:0030425	dendrite
1.29	2.49e-02	GO:0000139	Golgi membrane
1.74	4.49e-02	GO:0042383	sarcolemma

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.16	5.09e-25	GO:0005515	protein binding
1.07	2.26e-14	GO:0005488	binding
1.45	2.05e-10	GO:0043565	sequence-specific DNA binding
1.30	1.35e-06	GO:0030528	transcription regulator activity
1.29	4.41e-06	GO:0001071	nucleic acid binding transcription factor activity
1.29	4.41e-06	GO:0003700	sequence-specific DNA binding transcription factor activity
1.27	1.55e-03	GO:0019899	enzyme binding
1.31	3.18e-03	GO:0008092	cytoskeletal protein binding
1.52	6.55e-03	GO:0005244	voltage-gated ion channel activity
1.52	6.55e-03	GO:0022832	voltage-gated channel activity
1.33	8.33e-03	GO:0019904	protein domain specific binding
1.42	9.24e-03	GO:0005261	cation channel activity
1.39	1.16e-02	GO:0022836	gated channel activity
1.58	1.18e-02	GO:0022843	voltage-gated cation channel activity
1.38	1.42e-02	GO:0003779	actin binding
1.37	2.22e-02	GO:0016563	transcription activator activity
1.33	2.38e-02	GO:0005216	ion channel activity