Motif ID: GTF2I.p2

Z-value: 1.746


Transcription factors associated with GTF2I.p2:

Gene SymbolEntrez IDGene Name
GTF2I 2969 general transcription factor II, i

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
GTF2Ichr7_+_73709974-0.486.2e-02Click!


Activity profile for motif GTF2I.p2.

activity profile for motif GTF2I.p2


Sorted Z-values histogram for motif GTF2I.p2

Sorted Z-values for motif GTF2I.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GTF2I.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_-_66897584 3.421 NM_013246
 CLCF1
cardiotrophin-like cytokine factor 1
chr11_-_66898223 2.639 NM_001166212
 CLCF1
cardiotrophin-like cytokine factor 1
chr2_-_227371698 2.506 NM_005544
 IRS1
insulin receptor substrate 1
chr12_-_113606322 2.419 NM_005996
NM_016569
 TBX3

T-box 3

chr9_+_108665168 2.010 NM_021224
 ZNF462
zinc finger protein 462
chr15_+_41597097 1.817 NM_002373
 MAP1A
microtubule-associated protein 1A
chr2_-_19421852 1.816 NM_145260
 OSR1
odd-skipped related 1 (Drosophila)
chr11_-_56846246 1.730 TNKS1BP1
tankyrase 1 binding protein 1, 182kDa
chr16_+_84202515 1.728 NM_001134473
 KIAA0182
KIAA0182
chr3_-_187025438 1.696 IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr9_+_138341752 1.638 NM_001145638
NM_015597
 GPSM1

G-protein signaling modulator 1

chr19_-_36531958 1.540 NM_020856
 TSHZ3
teashirt zinc finger homeobox 3
chr1_+_221955876 1.525 NM_001146068
 CAPN2
calpain 2, (m/II) large subunit
chr11_+_12355600 1.509 NM_018222
 PARVA
parvin, alpha
chr3_-_187025501 1.484 NM_001007225
NM_006548
 IGF2BP2

insulin-like growth factor 2 mRNA binding protein 2

chr2_-_200030944 1.455 NM_001172509
 SATB2
SATB homeobox 2
chr11_-_78829342 1.449 NM_001098816
 ODZ4
odz, odd Oz/ten-m homolog 4 (Drosophila)
chr17_+_58058774 1.435 MRC2
mannose receptor, C type 2
chr6_+_1335067 1.403 NM_001452
 FOXF2
forkhead box F2
chr12_-_24606616 1.401 NM_152989
 SOX5
SRY (sex determining region Y)-box 5

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 164 entries
enrichment   p-value GO term description
2.59 9.94e-04 GO:0060688 regulation of morphogenesis of a branching structure
2.08 1.63e-03 GO:0090101 negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
2.01 3.39e-04 GO:0022612 gland morphogenesis
2.00 6.90e-04 GO:2000027 regulation of organ morphogenesis
1.72 4.38e-03 GO:0090092 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
1.71 1.83e-03 GO:0048705 skeletal system morphogenesis
1.66 2.72e-03 GO:0034330 cell junction organization
1.66 9.33e-03 GO:0034329 cell junction assembly
1.62 8.68e-12 GO:0048812 neuron projection morphogenesis
1.62 4.52e-08 GO:0001501 skeletal system development
1.61 8.34e-11 GO:0007409 axonogenesis
1.59 2.26e-12 GO:0000904 cell morphogenesis involved in differentiation
1.59 1.20e-10 GO:0048667 cell morphogenesis involved in neuron differentiation
1.59 5.26e-06 GO:0061061 muscle structure development
1.59 1.61e-02 GO:0048562 embryonic organ morphogenesis
1.57 1.72e-06 GO:0060284 regulation of cell development
1.57 2.30e-04 GO:0048568 embryonic organ development
1.57 1.95e-03 GO:0044087 regulation of cellular component biogenesis
1.57 4.64e-03 GO:0048732 gland development
1.56 7.46e-11 GO:0048858 cell projection morphogenesis

Gene overrepresentation in compartment category:

Showing 1 to 20 of 32 entries
enrichment   p-value GO term description
1.85 1.12e-02 GO:0031256 leading edge membrane
1.78 2.31e-03 GO:0001726 ruffle
1.77 9.80e-04 GO:0005925 focal adhesion
1.74 7.35e-04 GO:0030055 cell-substrate junction
1.74 4.49e-02 GO:0042383 sarcolemma
1.73 3.76e-07 GO:0031252 cell leading edge
1.71 2.69e-03 GO:0005924 cell-substrate adherens junction
1.68 8.20e-05 GO:0005912 adherens junction
1.62 2.61e-04 GO:0070161 anchoring junction
1.52 9.26e-06 GO:0015629 actin cytoskeleton
1.51 8.36e-03 GO:0030424 axon
1.50 1.42e-11 GO:0030054 cell junction
1.47 2.23e-02 GO:0030425 dendrite
1.44 1.36e-05 GO:0045202 synapse
1.44 1.03e-02 GO:0016323 basolateral plasma membrane
1.43 2.32e-05 GO:0043005 neuron projection
1.42 1.07e-04 GO:0031012 extracellular matrix
1.38 6.18e-03 GO:0044433 cytoplasmic vesicle part
1.37 1.35e-02 GO:0005578 proteinaceous extracellular matrix
1.30 1.67e-03 GO:0044431 Golgi apparatus part

Gene overrepresentation in function category:

Showing 1 to 17 of 17 entries
enrichment   p-value GO term description
1.58 1.18e-02 GO:0022843 voltage-gated cation channel activity
1.52 6.55e-03 GO:0005244 voltage-gated ion channel activity
1.52 6.55e-03 GO:0022832 voltage-gated channel activity
1.45 2.05e-10 GO:0043565 sequence-specific DNA binding
1.42 9.24e-03 GO:0005261 cation channel activity
1.39 1.16e-02 GO:0022836 gated channel activity
1.38 1.42e-02 GO:0003779 actin binding
1.37 2.22e-02 GO:0016563 transcription activator activity
1.33 8.33e-03 GO:0019904 protein domain specific binding
1.33 2.38e-02 GO:0005216 ion channel activity
1.31 3.18e-03 GO:0008092 cytoskeletal protein binding
1.30 1.35e-06 GO:0030528 transcription regulator activity
1.29 4.41e-06 GO:0001071 nucleic acid binding transcription factor activity
1.29 4.41e-06 GO:0003700 sequence-specific DNA binding transcription factor activity
1.27 1.55e-03 GO:0019899 enzyme binding
1.16 5.09e-25 GO:0005515 protein binding
1.07 2.26e-14 GO:0005488 binding