Motif ID: HAND1,2.p2

Z-value: 1.989


Transcription factors associated with HAND1,2.p2:

Gene SymbolEntrez IDGene Name
HAND1 9421 heart and neural crest derivatives expressed 1
HAND2 9464 heart and neural crest derivatives expressed 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
HAND2chr4_-_1746869180.175.2e-01Click!
HAND1chr5_-_153838013,
chr5_-_153837975		0.146.1e-01Click!


Activity profile for motif HAND1,2.p2.

activity profile for motif HAND1,2.p2


Sorted Z-values histogram for motif HAND1,2.p2

Sorted Z-values for motif HAND1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HAND1,2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr19_-_10074332 6.469 NM_031917
 ANGPTL6
angiopoietin-like 6
chr6_+_6533932 4.251 NM_004271
 LY86
lymphocyte antigen 86
chr11_+_66927976 4.242 NM_198517
 TBC1D10C
TBC1 domain family, member 10C
chr19_+_55614006 4.043 NM_003121
 SPIB
Spi-B transcription factor (Spi-1/PU.1 related)
chr5_-_149772563 3.587 CD74
CD74 molecule, major histocompatibility complex, class II invariant chain
chr7_+_99654806 3.468 NM_024070
 PVRIG
poliovirus receptor related immunoglobulin domain containing
chr22_+_23333610 3.081 NM_001032365
 GGT1
gamma-glutamyltransferase 1
chr4_-_40326603 2.964 NM_001098634
 RBM47
RNA binding motif protein 47
chr5_-_149772528 2.844


chr16_+_28413421 2.804 NM_018690
 APOBR
apolipoprotein B receptor
chr1_-_158948176 2.660 NM_001778
 CD48
CD48 molecule
chr15_+_42815851 2.574 NM_080745
NM_182985
 TRIM69

tripartite motif containing 69

chr12_+_111900650 2.522 NM_001032731
NM_002535
NM_016817
 OAS2


2'-5'-oligoadenylate synthetase 2, 69/71kDa


chr19_+_44886785 2.512 NM_020129
NM_203471
 LGALS14

lectin, galactoside-binding, soluble, 14

chr6_+_167445284 2.509 NM_004367
 CCR6
chemokine (C-C motif) receptor 6
chr6_-_133161318 2.497 NM_052831
 C6orf192
chromosome 6 open reading frame 192
chr3_+_99733432 2.456 NM_005290
 GPR15
G protein-coupled receptor 15
chr1_-_158815895 2.332 NM_001184879
NM_001184881
NM_001184882
NM_003874
 CD84



CD84 molecule



chr11_-_63087430 2.170 NM_017878
 HRASLS2
HRAS-like suppressor 2
chr1_+_159943385 2.161 NM_001184866
NM_001184867
NM_001184870
NM_001184871
NM_001184872
NM_001184873
NM_032738
 FCRLA






Fc receptor-like A







Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 4 of 4 entries
enrichment   p-value GO term description
3.71 4.95e-03 GO:0006959 humoral immune response
3.44 4.95e-02 GO:0007015 actin filament organization
1.99 1.24e-02 GO:0050776 regulation of immune response
1.72 1.77e-02 GO:0006955 immune response

Gene overrepresentation in compartment category:

Showing 1 to 4 of 4 entries
enrichment   p-value GO term description
1.41 7.38e-04 GO:0044459 plasma membrane part
1.35 1.09e-06 GO:0005886 plasma membrane
1.34 1.39e-06 GO:0071944 cell periphery
1.16 4.76e-02 GO:0044425 membrane part

Gene overrepresentation in function category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
4.80 5.29e-03 GO:0003823 antigen binding
3.17 6.00e-03 GO:0005179 hormone activity
3.01 3.64e-04 GO:0004252 serine-type endopeptidase activity
2.60 5.60e-03 GO:0008236 serine-type peptidase activity
2.55 7.66e-03 GO:0017171 serine hydrolase activity
1.46 2.02e-03 GO:0004872 receptor activity
1.37 1.54e-02 GO:0004871 signal transducer activity
1.37 1.54e-02 GO:0060089 molecular transducer activity