Motif ID: HBP1_HMGB_SSRP1_UBTF.p2

Z-value: 3.131


Transcription factors associated with HBP1_HMGB_SSRP1_UBTF.p2:

Gene SymbolEntrez IDGene Name
HBP1 26959 HMG-box transcription factor 1
HMGB2 3148 high-mobility group box 2
HMGB3 3149 high-mobility group box 3
SSRP1 6749 structure specific recognition protein 1
UBTF 7343 upstream binding transcription factor, RNA polymerase I

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
UBTFchr17_-_39651189-0.656.4e-03Click!
HBP1chr7_+_1065966410.639.0e-03Click!
SSRP1chr11_-_568599000.381.5e-01Click!
HMGB3chrX_+_1499024150.263.3e-01Click!
HMGB2chr4_-_174492029-0.194.9e-01Click!


Activity profile for motif HBP1_HMGB_SSRP1_UBTF.p2.

activity profile for motif HBP1_HMGB_SSRP1_UBTF.p2


Sorted Z-values histogram for motif HBP1_HMGB_SSRP1_UBTF.p2

Sorted Z-values for motif HBP1_HMGB_SSRP1_UBTF.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HBP1_HMGB_SSRP1_UBTF.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_+_12398514 11.563 NM_001168319
NM_001955
EDN1

endothelin 1

chr16_+_85169615 11.367 NM_005250
FOXL1
forkhead box L1
chr7_-_27186400 9.592 NM_153715
HOXA10
homeobox A10
chr7_+_134114957 9.479 CALD1
caldesmon 1
chr13_-_73605914 9.319 NM_007249
KLF12
Kruppel-like factor 12
chr7_+_134114912 9.206 CALD1
caldesmon 1
chr11_-_85107569 8.467 NM_206929
SYTL2
synaptotagmin-like 2
chr13_-_98428244 8.155 NM_001130048
NM_001130050
DOCK9

dedicator of cytokinesis 9

chr13_-_73606362 8.149 KLF12
Kruppel-like factor 12
chr6_-_111995213 8.102 NM_001164283
TRAF3IP2
TRAF3 interacting protein 2
chr11_-_85108030 7.792 NM_001162952
NM_206930
SYTL2

synaptotagmin-like 2

chr2_-_207738858 7.358 NM_003709
KLF7
Kruppel-like factor 7 (ubiquitous)
chr8_-_108579270 7.135 NM_001146
ANGPT1
angiopoietin 1
chr5_+_98132898 6.913 NM_001012761
RGMB
RGM domain family, member B
chr5_-_111119846 6.848 NM_001142483
C5orf13
chromosome 5 open reading frame 13
chr10_+_104525877 6.810 NM_017787
C10orf26
chromosome 10 open reading frame 26
chr2_-_162808123 6.702 NM_004460
FAP
fibroblast activation protein, alpha
chr7_-_27171673 6.615 NM_152739
HOXA9
homeobox A9
chr8_-_72436519 6.392 EYA1
eyes absent homolog 1 (Drosophila)
chr2_+_69093641 6.365 NM_018153
NM_032208
NM_053034
ANTXR1


anthrax toxin receptor 1


chr7_+_20337249 6.239 NM_002214
ITGB8
integrin, beta 8
chr6_+_130381408 6.134 NM_001007102
NM_032438
L3MBTL3

l(3)mbt-like 3 (Drosophila)

chr1_-_85816520 5.955 NM_001134445
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr6_-_128883125 5.947 NM_002844
NM_001135648
PTPRK

protein tyrosine phosphatase, receptor type, K

chr13_-_109757442 5.830 NM_001845
COL4A1
collagen, type IV, alpha 1
chr4_+_86918882 5.766 ARHGAP24
Rho GTPase activating protein 24
chr5_-_16989371 5.763 NM_012334
MYO10
myosin X
chr3_-_65999548 5.738 NM_001033057
NM_004742
NM_015520
MAGI1


membrane associated guanylate kinase, WW and PDZ domain containing 1


chr2_-_56266408 5.725 LOC100129434
hypothetical LOC100129434
chr3_-_11585264 5.680 NM_001128221
VGLL4
vestigial like 4 (Drosophila)
chr1_-_197173159 5.642 LOC100131234
familial acute myelogenous leukemia related factor
chr1_+_85819004 5.632 NM_001554
CYR61
cysteine-rich, angiogenic inducer, 61
chr7_+_28692122 5.574 NM_001011666
CREB5
cAMP responsive element binding protein 5
chr5_-_16989290 5.449 MYO10
myosin X
chr2_+_33213111 5.385 NM_000627
NM_001166264
NM_001166265
NM_001166266
LTBP1



latent transforming growth factor beta binding protein 1



chr10_+_86174665 5.335 FAM190B
family with sequence similarity 190, member B
chr3_-_115825742 5.333 NM_001164347
ZBTB20
zinc finger and BTB domain containing 20
chr9_+_108665168 5.277 NM_021224
ZNF462
zinc finger protein 462
chr9_+_18464090 5.239 NM_001040272
NM_052866
ADAMTSL1

ADAMTS-like 1

chr8_-_124622434 5.169 NM_058229
FBXO32
F-box protein 32
chr8_+_67201684 5.155 NM_033058
NM_184085
NM_184086
NM_184087
TRIM55



tripartite motif containing 55



chr9_+_18464138 5.096 ADAMTSL1
ADAMTS-like 1
chr6_-_134540666 4.959 NM_001143677
SGK1
serum/glucocorticoid regulated kinase 1
chr2_+_12775814 4.937


chr3_-_116272911 4.935 NM_001164343
ZBTB20
zinc finger and BTB domain containing 20
chr4_-_141293572 4.759 MAML3
mastermind-like 3 (Drosophila)
chr18_+_3441589 4.646 NM_170695
NM_173210
TGIF1

TGFB-induced factor homeobox 1

chr6_-_56824672 4.642 DST
dystonin
chr7_-_27153892 4.563 NM_024014
HOXA6
homeobox A6
chr3_-_194118321 4.527 MB21D2
Mab-21 domain containing 2
chr3_+_100840129 4.456 NM_001850
NM_020351
COL8A1

collagen, type VIII, alpha 1

chr7_-_27171648 4.382 HOXA9
homeobox A9
chr4_+_146623405 4.381 NM_001003688
SMAD1
SMAD family member 1
chr12_+_13240983 4.325 EMP1
epithelial membrane protein 1
chr7_-_27108826 4.278 NM_006735
HOXA2
homeobox A2
chr9_-_16717887 4.236 BNC2
basonuclin 2
chr5_+_15553736 4.235 FBXL7
F-box and leucine-rich repeat protein 7
chr21_-_27261276 4.214 NM_007038
ADAMTS5
ADAM metallopeptidase with thrombospondin type 1 motif, 5
chr7_-_83662152 4.211 NM_006080
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr3_-_150533948 4.199 NM_001184723
NM_138786
TM4SF18

transmembrane 4 L six family member 18

chr12_+_13240987 4.197 EMP1
epithelial membrane protein 1
chr2_-_164300758 4.186 NM_018086
FIGN
fidgetin
chr3_-_11660395 4.131 NM_001128219
VGLL4
vestigial like 4 (Drosophila)
chr9_-_14303509 4.120 NFIB
nuclear factor I/B
chr3_-_55496370 4.101 NM_003392
WNT5A
wingless-type MMTV integration site family, member 5A
chr7_-_27171600 4.068 HOXA9
homeobox A9
chr6_-_139654807 4.015 NM_153235
TXLNB
taxilin beta
chr14_+_85066265 4.012 FLRT2
fibronectin leucine rich transmembrane protein 2
chr9_+_102380156 4.002 NM_001018116
MURC
muscle-related coiled-coil protein
chr7_+_102340579 3.966 NM_001031692
NM_005824
LRRC17

leucine rich repeat containing 17

chr14_+_85066207 3.925 NM_013231
FLRT2
fibronectin leucine rich transmembrane protein 2
chr9_-_14303899 3.920 NFIB
nuclear factor I/B
chr2_+_12775336 3.915 TRIB2
tribbles homolog 2 (Drosophila)
chr4_-_141294682 3.888 NM_018717
MAML3
mastermind-like 3 (Drosophila)
chr8_+_70567634 3.886 SULF1
sulfatase 1
chr4_+_141397889 3.867 NM_032547
SCOC
short coiled-coil protein
chrX_-_19598912 3.852 NM_001184960
SH3KBP1
SH3-domain kinase binding protein 1
chrX_+_15428820 3.802 NM_203281
BMX
BMX non-receptor tyrosine kinase
chrX_+_86659370 3.788 NM_019117
NM_057162
KLHL4

kelch-like 4 (Drosophila)

chr1_-_199742589 3.771 NM_001193571
CSRP1
cysteine and glycine-rich protein 1
chr7_+_93388951 3.767 NM_004126
GNG11
guanine nucleotide binding protein (G protein), gamma 11
chr8_+_70567581 3.744 NM_001128205
NM_001128206
SULF1

sulfatase 1

chr9_-_14304036 3.687 NM_001190737
NM_005596
NFIB

nuclear factor I/B

chr3_-_55496607 3.666 WNT5A
wingless-type MMTV integration site family, member 5A
chr5_+_15553539 3.553 FBXL7
F-box and leucine-rich repeat protein 7
chr1_-_191422346 3.540 NM_003783
B3GALT2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr8_-_72437020 3.530 NM_000503
EYA1
eyes absent homolog 1 (Drosophila)
chr7_+_20336849 3.510 ITGB8
integrin, beta 8
chr4_-_101658094 3.487 NM_001159694
NM_016242
EMCN

endomucin

chr18_-_21184824 3.479


chr5_+_15553288 3.473 NM_012304
FBXL7
F-box and leucine-rich repeat protein 7
chr4_-_140696740 3.456 NM_030648
SETD7
SET domain containing (lysine methyltransferase) 7
chr15_+_64781723 3.441 NM_005585
SMAD6
SMAD family member 6
chr12_-_88270375 3.433 NM_001946
NM_022652
DUSP6

dual specificity phosphatase 6

chr6_+_114285209 3.428 NM_002356
MARCKS
myristoylated alanine-rich protein kinase C substrate
chr1_-_85703198 3.381 DDAH1
dimethylarginine dimethylaminohydrolase 1
chr7_+_27190688 3.326


chr14_+_22375753 3.282 MMP14
matrix metallopeptidase 14 (membrane-inserted)
chr15_+_45797977 3.240 NM_020858
NM_024966
NM_153616
NM_153617
NM_153618
NM_153619
SEMA6D





sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D





chr6_-_56824371 3.207 DST
dystonin
chr2_-_188021117 3.198 NM_005795
CALCRL
calcitonin receptor-like
chr11_+_112337199 3.193 NM_000615
NM_001076682
NM_181351
NCAM1


neural cell adhesion molecule 1


chr6_+_153060722 3.170 NM_025107
MYCT1
myc target 1
chr4_-_7991992 3.158 NM_001134647
NM_198595
AFAP1

actin filament associated protein 1

chr4_+_86918870 3.152 NM_001042669
ARHGAP24
Rho GTPase activating protein 24
chr1_+_39647762 3.139 NM_015038
KIAA0754
KIAA0754
chr2_-_151052391 3.135 NM_005168
RND3
Rho family GTPase 3
chr9_-_4289915 3.130 GLIS3
GLIS family zinc finger 3
chr7_-_27190882 3.129 HOXA11
homeobox A11
chr21_-_38792173 3.108 NM_001136155
NM_182918
ERG

v-ets erythroblastosis virus E26 oncogene homolog (avian)

chr3_+_148593911 3.103


chr4_-_138673078 3.099 NM_019035
PCDH18
protocadherin 18
chr15_-_81667169 3.093 NM_016073
HDGFRP3
hepatoma-derived growth factor, related protein 3
chr7_+_134114701 3.083 NM_004342
NM_033138
NM_033157
CALD1


caldesmon 1


chr1_-_95165089 3.074 NM_001839
CNN3
calponin 3, acidic
chr19_+_13767207 3.066 NM_023072
ZSWIM4
zinc finger, SWIM-type containing 4
chr6_+_31190505 3.041 NM_014068
PSORS1C1
psoriasis susceptibility 1 candidate 1
chr3_-_194118627 3.039 NM_178496
MB21D2
Mab-21 domain containing 2
chr14_+_22375747 3.027 MMP14
matrix metallopeptidase 14 (membrane-inserted)
chr12_-_24606616 3.025 NM_152989
SOX5
SRY (sex determining region Y)-box 5
chr16_-_71639670 3.014 NM_006885
ZFHX3
zinc finger homeobox 3
chr5_+_61910318 3.014 NM_181506
LRRC70
leucine rich repeat containing 70
chr17_-_76985538 3.003


chr11_+_129496792 2.996 APLP2
amyloid beta (A4) precursor-like protein 2
chrX_-_50573759 2.987 NM_020717
SHROOM4
shroom family member 4
chr20_+_19818209 2.978 NM_018993
RIN2
Ras and Rab interactor 2
chr13_-_32678142 2.973 NM_052851
STARD13
StAR-related lipid transfer (START) domain containing 13
chr4_+_3264509 2.966 RGS12
regulator of G-protein signaling 12
chr15_-_68781662 2.946 NM_001008224
UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr8_-_72436832 2.928 EYA1
eyes absent homolog 1 (Drosophila)
chr22_+_36928972 2.922 NM_001161573
MAFF
v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)
chr5_-_121441910 2.902 NM_002317
LOX
lysyl oxidase
chr15_+_37330176 2.898 NM_207445
C15orf54
chromosome 15 open reading frame 54
chr2_-_175578156 2.879 NM_001025201
NM_001822
CHN1

chimerin (chimaerin) 1

chr9_+_36026900 2.877 NM_021111
RECK
reversion-inducing-cysteine-rich protein with kazal motifs
chr2_+_85834111 2.863 NM_032827
ATOH8
atonal homolog 8 (Drosophila)
chr1_+_198975227 2.845 NM_203459
CAMSAP1L1
calmodulin regulated spectrin-associated protein 1-like 1
chr19_-_45016587 2.838 NM_004714
NM_006483
NM_006484
DYRK1B


dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B


chrX_+_135079461 2.832 NM_001167819
FHL1
four and a half LIM domains 1
chr2_-_110665188 2.815 NM_033514
LIMS3-LOC440895
LIMS3
LIMS3-LOC440895 read-through
LIM and senescent cell antigen-like domains 3
chr5_-_121441866 2.799 LOX
lysyl oxidase
chr2_+_108637698 2.790 NM_001193485
LIMS1
LIM and senescent cell antigen-like domains 1
chr1_+_68070573 2.771


chr2_+_110013297 2.755 NM_033514
LIMS3-LOC440895
LIMS3
LIMS3-LOC440895 read-through
LIM and senescent cell antigen-like domains 3
chr5_-_121441805 2.737 LOX
lysyl oxidase
chr5_-_146813343 2.735 NM_001387
DPYSL3
dihydropyrimidinase-like 3
chr7_-_27149750 2.708 NM_019102
HOXA5
homeobox A5
chr1_-_199742841 2.695 CSRP1
cysteine and glycine-rich protein 1
chr3_+_29297806 2.695 NM_001003792
NM_001003793
NM_001177711
NM_001177712
NM_014483
RBMS3




RNA binding motif, single stranded interacting protein 3




chr1_-_68470585 2.681 NM_001002292
NM_001193334
NM_024911
WLS


wntless homolog (Drosophila)


chr1_+_216585298 2.666 NM_001135599
NM_003238
TGFB2

transforming growth factor, beta 2

chrX_+_135079120 2.665 NM_001159704
FHL1
four and a half LIM domains 1
chr17_+_16886491 2.651 NM_015134
NM_201274
MPRIP

myosin phosphatase Rho interacting protein

chrX_-_99778340 2.641 NM_003270
TSPAN6
tetraspanin 6
chr13_+_110653407 2.634 ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr6_+_144040751 2.611 NM_001100164
NM_001100165
PHACTR2

phosphatase and actin regulator 2

chr22_+_44828338 2.609


chr2_+_108637916 2.601 LIMS1
LIMS3
LIM and senescent cell antigen-like domains 1
LIM and senescent cell antigen-like domains 3
chr15_+_22751162 2.593 NM_003097
NM_022804
NM_005678
SNRPN
SNURF

small nuclear ribonucleoprotein polypeptide N
SNRPN upstream reading frame

chr13_-_20533703 2.583 NM_014572
LATS2
LATS, large tumor suppressor, homolog 2 (Drosophila)
chr11_-_85074848 2.563 NM_152723
CCDC89
coiled-coil domain containing 89
chr8_-_6407882 2.541 NM_001118887
NM_001118888
NM_001147
ANGPT2


angiopoietin 2


chr18_-_51406359 2.538 TCF4
transcription factor 4
chr7_+_28415495 2.522 LOC401317
hypothetical LOC401317
chr6_+_89847019 2.514 NM_006813
PNRC1
proline-rich nuclear receptor coactivator 1
chr20_-_49612745 2.504 NFATC2
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
chr19_-_3920736 2.497 NM_001348
DAPK3
death-associated protein kinase 3
chr7_-_41709191 2.482 NM_002192
INHBA
inhibin, beta A
chr14_+_62740878 2.474 NM_020663
RHOJ
ras homolog gene family, member J
chr5_-_83715947 2.467 EDIL3
EGF-like repeats and discoidin I-like domains 3
chr6_+_136214495 2.463 NM_018945
PDE7B
phosphodiesterase 7B
chr18_+_7936885 2.446 PTPRM
protein tyrosine phosphatase, receptor type, M
chr1_-_199742871 2.438 NM_001193570
NM_004078
CSRP1

cysteine and glycine-rich protein 1

chr1_-_199742864 2.420 CSRP1
cysteine and glycine-rich protein 1
chr9_+_81377289 2.412 TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr12_+_13240868 2.395 NM_001423
EMP1
epithelial membrane protein 1
chr8_-_29262240 2.364 NM_057158
DUSP4
dual specificity phosphatase 4
chr9_+_81377419 2.363 TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr1_-_177378801 2.360 NM_001136000
NM_001168239
NM_005158
ABL2


v-abl Abelson murine leukemia viral oncogene homolog 2


chr9_+_117955890 2.353 NM_002581
PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chr1_-_223907283 2.345 NM_001008493
NM_018212
ENAH

enabled homolog (Drosophila)

chr13_+_109757593 2.344 NM_001846
COL4A2
collagen, type IV, alpha 2
chr15_-_81667773 2.329 HDGFRP3
hepatoma-derived growth factor, related protein 3
chr7_+_115952279 2.322 NM_001172895
CAV1
caveolin 1, caveolae protein, 22kDa
chr4_-_111777651 2.318 PITX2
paired-like homeodomain 2
chr12_+_14409875 2.314 NM_018179
ATF7IP
activating transcription factor 7 interacting protein
chr7_-_47588266 2.314 TNS3
tensin 3
chr5_+_15553768 2.308 FBXL7
F-box and leucine-rich repeat protein 7
chr14_+_76297885 2.305 NM_014909
VASH1
vasohibin 1
chr13_-_32658215 2.300 NM_178007
STARD13
StAR-related lipid transfer (START) domain containing 13
chr1_-_242073094 2.298 NM_005465
NM_181690
AKT3

v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)

chr1_+_112740378 2.298


chr1_+_112740380 2.297 LOC100129406
CTTNBP2NL
hypothetical protein LOC100129406
CTTNBP2 N-terminal like
chr3_-_116348780 2.291 NM_015642
ZBTB20
zinc finger and BTB domain containing 20
chrX_-_10548458 2.285 NM_000381
NM_033289
MID1

midline 1 (Opitz/BBB syndrome)

chr1_+_15145001 2.282 NM_001017999
KAZN
kazrin, periplakin interacting protein
chr2_-_144991386 2.280 ZEB2
zinc finger E-box binding homeobox 2
chr11_+_57547928 2.265 NM_001005212
OR9Q1
olfactory receptor, family 9, subfamily Q, member 1
chr1_+_112740322 2.265 NM_018704
CTTNBP2NL
CTTNBP2 N-terminal like
chr12_+_62524778 2.256 NM_020762
SRGAP1
SLIT-ROBO Rho GTPase activating protein 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.44 1.91e-19 GO:0007275 multicellular organismal development
1.32 5.51e-19 GO:0032501 multicellular organismal process
1.40 4.11e-18 GO:0032502 developmental process
1.47 1.71e-17 GO:0048731 system development
1.43 6.49e-17 GO:0048856 anatomical structure development
1.57 1.94e-11 GO:0009653 anatomical structure morphogenesis
1.57 2.82e-11 GO:0007399 nervous system development
1.43 2.09e-09 GO:0030154 cell differentiation
1.42 4.97e-09 GO:0048869 cellular developmental process
3.47 3.29e-08 GO:0030336 negative regulation of cell migration
3.47 3.29e-08 GO:2000146 negative regulation of cell motility
3.31 8.14e-08 GO:0051271 negative regulation of cellular component movement
1.89 1.74e-07 GO:0072358 cardiovascular system development
1.89 1.74e-07 GO:0072359 circulatory system development
1.66 9.17e-07 GO:0007155 cell adhesion
1.66 9.17e-07 GO:0022610 biological adhesion
3.05 1.21e-06 GO:0040013 negative regulation of locomotion
1.82 1.67e-06 GO:0000904 cell morphogenesis involved in differentiation
2.08 3.01e-06 GO:0001944 vasculature development
1.64 3.01e-06 GO:2000026 regulation of multicellular organismal development
1.58 3.25e-06 GO:0022008 neurogenesis
1.71 3.27e-06 GO:0032989 cellular component morphogenesis
1.33 4.16e-06 GO:0048519 negative regulation of biological process
1.38 4.23e-06 GO:0048513 organ development
2.11 4.43e-06 GO:0001568 blood vessel development
1.35 5.52e-06 GO:0048523 negative regulation of cellular process
1.69 5.74e-06 GO:0007167 enzyme linked receptor protein signaling pathway
1.72 6.35e-06 GO:0000902 cell morphogenesis
1.83 1.22e-05 GO:0048667 cell morphogenesis involved in neuron differentiation
1.31 1.82e-05 GO:0048522 positive regulation of cellular process
1.84 1.87e-05 GO:0007409 axonogenesis
1.56 2.20e-05 GO:0040011 locomotion
1.29 4.17e-05 GO:0048518 positive regulation of biological process
1.94 4.26e-05 GO:0001501 skeletal system development
1.55 4.36e-05 GO:0048699 generation of neurons
2.04 5.45e-05 GO:0030334 regulation of cell migration
1.61 6.18e-05 GO:0030182 neuron differentiation
1.78 6.39e-05 GO:0048812 neuron projection morphogenesis
1.15 6.69e-05 GO:0050794 regulation of cellular process
2.02 9.01e-05 GO:2000145 regulation of cell motility
1.16 1.22e-04 GO:0050896 response to stimulus
1.51 1.76e-04 GO:0050793 regulation of developmental process
1.70 2.02e-04 GO:0048858 cell projection morphogenesis
1.93 2.96e-04 GO:0051270 regulation of cellular component movement
1.68 3.16e-04 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.69 3.16e-04 GO:0032990 cell part morphogenesis
1.91 3.99e-04 GO:0030029 actin filament-based process
1.63 4.57e-04 GO:0048666 neuron development
1.13 4.90e-04 GO:0050789 regulation of biological process
1.68 5.50e-04 GO:0031175 neuron projection development
1.49 5.62e-04 GO:0048468 cell development
1.89 5.65e-04 GO:0016337 cell-cell adhesion
1.22 9.98e-04 GO:0007165 signal transduction
1.33 1.04e-03 GO:0003008 system process
1.58 1.16e-03 GO:0030030 cell projection organization
1.12 1.27e-03 GO:0065007 biological regulation
1.87 1.31e-03 GO:0040012 regulation of locomotion
1.54 1.83e-03 GO:0009790 embryo development
1.79 2.45e-03 GO:0007411 axon guidance
1.97 2.46e-03 GO:0048011 nerve growth factor receptor signaling pathway
1.56 2.90e-03 GO:0045893 positive regulation of transcription, DNA-dependent
1.53 3.06e-03 GO:0045595 regulation of cell differentiation
1.67 3.21e-03 GO:0023057 negative regulation of signaling
1.20 3.52e-03 GO:0023052 signaling
1.50 3.54e-03 GO:0010557 positive regulation of macromolecule biosynthetic process
1.43 3.88e-03 GO:0032879 regulation of localization
1.96 4.60e-03 GO:0048514 blood vessel morphogenesis
2.26 4.94e-03 GO:0048705 skeletal system morphogenesis
1.61 5.00e-03 GO:0048585 negative regulation of response to stimulus
1.47 5.08e-03 GO:0051128 regulation of cellular component organization
2.22 5.95e-03 GO:0007156 homophilic cell adhesion
1.88 6.35e-03 GO:0030036 actin cytoskeleton organization
1.65 6.78e-03 GO:0010648 negative regulation of cell communication
1.67 6.96e-03 GO:0009968 negative regulation of signal transduction
1.32 8.18e-03 GO:0023051 regulation of signaling
1.82 8.63e-03 GO:0061061 muscle structure development
2.09 8.97e-03 GO:0009952 anterior/posterior pattern formation
1.42 9.02e-03 GO:0006357 regulation of transcription from RNA polymerase II promoter
2.58 9.36e-03 GO:0048706 embryonic skeletal system development
2.29 9.51e-03 GO:0006469 negative regulation of protein kinase activity
1.65 1.05e-02 GO:0007608 sensory perception of smell
1.87 1.28e-02 GO:0003002 regionalization
1.65 1.32e-02 GO:0016477 cell migration
1.55 1.37e-02 GO:0006928 cellular component movement
1.39 1.67e-02 GO:0010646 regulation of cell communication
1.49 1.82e-02 GO:0010628 positive regulation of gene expression
1.66 2.59e-02 GO:0009792 embryo development ending in birth or egg hatching
1.32 2.87e-02 GO:0009966 regulation of signal transduction
3.01 2.91e-02 GO:0010594 regulation of endothelial cell migration
1.69 2.92e-02 GO:0007389 pattern specification process
1.59 3.02e-02 GO:0048870 cell motility
1.59 3.02e-02 GO:0051674 localization of cell
1.34 3.13e-02 GO:0051239 regulation of multicellular organismal process
1.48 3.13e-02 GO:0051254 positive regulation of RNA metabolic process
1.66 3.22e-02 GO:0043009 chordate embryonic development
1.66 3.22e-02 GO:0048598 embryonic morphogenesis
2.18 3.23e-02 GO:0033673 negative regulation of kinase activity
2.80 3.24e-02 GO:0016202 regulation of striated muscle tissue development
1.51 3.72e-02 GO:0009887 organ morphogenesis
1.41 3.85e-02 GO:0006351 transcription, DNA-dependent
1.44 3.94e-02 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.24 4.26e-02 GO:0048736 appendage development
2.24 4.26e-02 GO:0060173 limb development
1.43 4.34e-02 GO:0051173 positive regulation of nitrogen compound metabolic process
1.50 4.37e-02 GO:0010629 negative regulation of gene expression
2.75 4.39e-02 GO:0010810 regulation of cell-substrate adhesion
1.42 4.43e-02 GO:0007600 sensory perception
1.56 4.60e-02 GO:0007606 sensory perception of chemical stimulus

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.23 4.97e-07 GO:0071944 cell periphery
1.23 7.60e-07 GO:0005886 plasma membrane
1.98 9.30e-07 GO:0005578 proteinaceous extracellular matrix
1.85 4.94e-06 GO:0031012 extracellular matrix
1.64 1.11e-05 GO:0030054 cell junction
2.32 2.25e-05 GO:0005912 adherens junction
2.80 3.01e-05 GO:0030027 lamellipodium
2.47 1.39e-04 GO:0030055 cell-substrate junction
2.54 1.58e-04 GO:0005925 focal adhesion
2.14 2.04e-04 GO:0070161 anchoring junction
2.42 5.42e-04 GO:0005924 cell-substrate adherens junction
2.29 1.35e-03 GO:0044420 extracellular matrix part
1.97 2.28e-03 GO:0031252 cell leading edge
2.17 7.01e-03 GO:0030016 myofibril
2.11 9.75e-03 GO:0043292 contractile fiber
1.28 1.04e-02 GO:0005856 cytoskeleton
3.33 1.06e-02 GO:0042641 actomyosin
2.15 1.07e-02 GO:0044449 contractile fiber part
7.85 1.59e-02 GO:0071437 invadopodium
1.34 1.66e-02 GO:0044421 extracellular region part

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.94 3.70e-06 GO:0003779 actin binding
1.48 1.80e-05 GO:0030528 transcription regulator activity
1.49 2.01e-05 GO:0001071 nucleic acid binding transcription factor activity
1.49 2.01e-05 GO:0003700 sequence-specific DNA binding transcription factor activity
1.67 2.49e-05 GO:0008092 cytoskeletal protein binding
1.54 4.40e-04 GO:0005509 calcium ion binding
1.66 2.59e-03 GO:0004984 olfactory receptor activity
1.48 4.17e-03 GO:0043565 sequence-specific DNA binding
2.58 5.49e-03 GO:0005089 Rho guanyl-nucleotide exchange factor activity
2.21 1.01e-02 GO:0017124 SH3 domain binding
2.18 3.59e-02 GO:0004222 metalloendopeptidase activity
2.24 3.79e-02 GO:0005088 Ras guanyl-nucleotide exchange factor activity
1.62 4.82e-02 GO:0016563 transcription activator activity