Motif ID: HSF1,2.p2

Z-value: 1.287


Transcription factors associated with HSF1,2.p2:

Gene SymbolEntrez IDGene Name
HSF1 3297 heat shock transcription factor 1
HSF2 3298 heat shock transcription factor 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
HSF1chr8_+_1454862450.562.3e-02Click!
HSF2chr6_+_1227623840.312.5e-01Click!


Activity profile for motif HSF1,2.p2.

activity profile for motif HSF1,2.p2


Sorted Z-values histogram for motif HSF1,2.p2

Sorted Z-values for motif HSF1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HSF1,2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_-_152366970 2.224 NM_001009555
NM_001128923
 SH3D19

SH3 domain containing 19

chr13_+_48582389 2.122 NM_014923
 FNDC3A
fibronectin type III domain containing 3A
chr14_+_62740878 1.895 NM_020663
 RHOJ
ras homolog gene family, member J
chr9_+_130485926 1.827 SET
SET nuclear oncogene
chr20_+_19818209 1.816 NM_018993
 RIN2
Ras and Rab interactor 2
chr9_+_130485754 1.790 NM_001122821
 SET
SET nuclear oncogene
chr12_-_119172339 1.788 NM_025157
 PXN
paxillin
chr17_+_7199178 1.780 NM_198154
 TMEM95
transmembrane protein 95
chr6_+_151688327 1.717 NM_144497
 AKAP12
A kinase (PRKA) anchor protein 12
chr4_-_153820535 1.682 NM_152680
 TMEM154
transmembrane protein 154
chr20_-_17487480 1.663 NM_001161705
 BFSP1
beaded filament structural protein 1, filensin
chr5_-_148422799 1.617 NM_024577
 SH3TC2
SH3 domain and tetratricopeptide repeats 2
chr7_+_134114957 1.585 CALD1
caldesmon 1
chr3_+_191588354 1.484 NM_006580
 CLDN16
claudin 16
chr18_-_44723116 1.480 NM_001190823
 SMAD7
SMAD family member 7
chr19_-_54258935 1.457 NM_006179
 NTF4
neurotrophin 4
chr16_+_54158084 1.416 NM_032330
 CAPNS2
calpain, small subunit 2
chr7_+_134114701 1.339 NM_004342
NM_033138
NM_033157
 CALD1


caldesmon 1


chr3_+_195336625 1.325 NM_005524
 HES1
hairy and enhancer of split 1, (Drosophila)
chr11_+_12265022 1.316 NM_032867
 MICALCL
MICAL C-terminal like

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 25 entries
enrichment   p-value GO term description
2.20 1.96e-02 GO:0001525 angiogenesis
2.03 2.11e-02 GO:0048514 blood vessel morphogenesis
2.02 2.70e-03 GO:0001568 blood vessel development
1.98 2.24e-03 GO:0001944 vasculature development
1.89 4.11e-05 GO:0048646 anatomical structure formation involved in morphogenesis
1.70 1.89e-03 GO:0006928 cellular component movement
1.67 2.77e-02 GO:0072358 cardiovascular system development
1.67 2.77e-02 GO:0072359 circulatory system development
1.62 4.62e-02 GO:0006935 chemotaxis
1.62 4.62e-02 GO:0042330 taxis
1.59 2.50e-04 GO:0040011 locomotion
1.56 4.83e-02 GO:0032989 cellular component morphogenesis
1.46 5.89e-03 GO:0022607 cellular component assembly
1.45 1.28e-04 GO:0009653 anatomical structure morphogenesis
1.42 1.43e-02 GO:0044085 cellular component biogenesis
1.39 9.78e-03 GO:0009966 regulation of signal transduction
1.31 1.11e-02 GO:0048869 cellular developmental process
1.28 1.91e-04 GO:0048856 anatomical structure development
1.27 4.34e-03 GO:0048731 system development
1.26 3.75e-04 GO:0007275 multicellular organismal development

Gene overrepresentation in compartment category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
2.39 1.97e-02 GO:0005925 focal adhesion
2.37 1.09e-02 GO:0030055 cell-substrate junction
2.37 1.60e-02 GO:0005924 cell-substrate adherens junction
2.21 1.42e-03 GO:0070161 anchoring junction
2.18 6.25e-03 GO:0005912 adherens junction
1.43 2.93e-03 GO:0044421 extracellular region part
1.32 1.41e-02 GO:0005856 cytoskeleton

Gene overrepresentation in function category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
1.19 5.62e-09 GO:0005515 protein binding