Motif ID: IKZF1.p2

Z-value: 1.512


Transcription factors associated with IKZF1.p2:

Gene SymbolEntrez IDGene Name
IKZF1 10320 IKAROS family zinc finger 1 (Ikaros)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
IKZF1chr7_+_50314801-0.411.2e-01Click!


Activity profile for motif IKZF1.p2.

activity profile for motif IKZF1.p2


Sorted Z-values histogram for motif IKZF1.p2

Sorted Z-values for motif IKZF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of IKZF1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_-_95720870 1.978 LOC100288748
hypothetical LOC100288748
chr2_-_113310796 1.629 NM_000576
 IL1B
interleukin 1, beta
chr5_+_66160359 1.498 NM_015183
 MAST4
microtubule associated serine/threonine kinase family member 4
chr1_-_151855413 1.434 NM_020672
 S100A14
S100 calcium binding protein A14
chr1_-_23393808 1.416 NM_000864
 HTR1D
5-hydroxytryptamine (serotonin) receptor 1D
chr1_+_31814709 1.371 TINAGL1
tubulointerstitial nephritis antigen-like 1
chr1_+_31814672 1.370 NM_022164
 TINAGL1
tubulointerstitial nephritis antigen-like 1
chr1_+_117253882 1.344 NM_020440
 PTGFRN
prostaglandin F2 receptor negative regulator
chr15_+_38923470 1.308 NM_003710
NM_181642
 SPINT1

serine peptidase inhibitor, Kunitz type 1

chr1_+_26728846 1.267 RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr11_+_20001130 1.256 NM_001111019
 NAV2
neuron navigator 2
chr3_+_42176662 1.253 NM_014965
 TRAK1
trafficking protein, kinesin binding 1
chr4_+_128773529 1.228 NM_015693
 INTU
inturned planar cell polarity effector homolog (Drosophila)
chr3_-_139315011 1.188 NM_001170538
 DZIP1L
DAZ interacting protein 1-like
chr1_+_26728827 1.164 NM_002953
 RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr1_+_26728839 1.137 RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr11_+_20000938 1.132 NAV2
neuron navigator 2
chr1_-_207892420 1.130 NM_000228
 LAMB3
laminin, beta 3
chr12_+_50913274 1.119 KRT7
keratin 7
chr12_-_56447090 1.116 NM_000785
 CYP27B1
cytochrome P450, family 27, subfamily B, polypeptide 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 13 of 13 entries
enrichment   p-value GO term description
1.79 3.84e-03 GO:0051056 regulation of small GTPase mediated signal transduction
1.71 1.71e-02 GO:0006886 intracellular protein transport
1.63 1.05e-02 GO:0070727 cellular macromolecule localization
1.60 2.67e-02 GO:0034613 cellular protein localization
1.48 1.49e-02 GO:0033554 cellular response to stress
1.45 2.88e-03 GO:0008104 protein localization
1.45 2.45e-02 GO:0045184 establishment of protein localization
1.45 4.12e-02 GO:0015031 protein transport
1.39 4.89e-03 GO:0033036 macromolecule localization
1.24 1.88e-02 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.21 3.44e-02 GO:0016043 cellular component organization
1.13 3.54e-02 GO:0044237 cellular metabolic process
1.10 1.43e-06 GO:0009987 cellular process

Gene overrepresentation in compartment category:

Showing 1 to 10 of 10 entries
enrichment   p-value GO term description
1.78 3.48e-02 GO:0016323 basolateral plasma membrane
1.39 3.40e-07 GO:0005829 cytosol
1.20 8.84e-08 GO:0044444 cytoplasmic part
1.16 6.45e-09 GO:0005737 cytoplasm
1.14 5.88e-03 GO:0044446 intracellular organelle part
1.14 7.02e-03 GO:0044422 organelle part
1.09 3.18e-02 GO:0043231 intracellular membrane-bounded organelle
1.09 3.19e-02 GO:0043227 membrane-bounded organelle
1.08 3.37e-05 GO:0005622 intracellular
1.08 1.22e-04 GO:0044424 intracellular part

Gene overrepresentation in function category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
1.13 5.11e-04 GO:0005515 protein binding