Motif ID: KLF12.p2

Z-value: 3.068


Transcription factors associated with KLF12.p2:

Gene SymbolEntrez IDGene Name
KLF12 11278 Kruppel-like factor 12

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
KLF12chr13_-_736063620.421.1e-01Click!


Activity profile for motif KLF12.p2.

activity profile for motif KLF12.p2


Sorted Z-values histogram for motif KLF12.p2

Sorted Z-values for motif KLF12.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of KLF12.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr16_-_66535923 3.490 SLC12A4
solute carrier family 12 (potassium/chloride transporters), member 4
chr9_+_136673464 2.806 NM_000093
 COL5A1
collagen, type V, alpha 1
chr3_-_130761967 2.658 PLXND1
plexin D1
chr16_-_66535457 2.465 NM_000229
 LCAT
lecithin-cholesterol acyltransferase
chr17_+_1580504 2.446 WDR81
WD repeat domain 81
chr16_+_31132842 2.411 NM_001008274
 TRIM72
tripartite motif containing 72
chr2_+_85834111 2.194 NM_032827
 ATOH8
atonal homolog 8 (Drosophila)
chr7_+_149699185 1.939 NM_014374
 REPIN1
replication initiator 1
chrX_+_152699616 1.910 NM_001170760
NM_001170761
NM_014370
 SRPK3


SRSF protein kinase 3


chr9_+_136673534 1.888 COL5A1
collagen, type V, alpha 1
chr15_+_38550451 1.830 NM_130468
 CHST14
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14
chr5_+_34692239 1.807 RAI14
retinoic acid induced 14
chr16_+_82490230 1.735 NM_012213
 MLYCD
malonyl-CoA decarboxylase
chr7_-_27180398 1.706 NM_018951
 HOXA10
homeobox A10
chr16_+_27320983 1.696 NM_181078
NM_181079
 IL21R

interleukin 21 receptor

chr13_-_110365336 1.661 ANKRD10
ankyrin repeat domain 10
chr5_+_34692352 1.651 NM_001145520
 RAI14
retinoic acid induced 14
chr4_+_2783764 1.610 SH3BP2
SH3-domain binding protein 2
chr2_-_219791902 1.590 NM_005689
 ABCB6
ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr7_-_75206152 1.576 HIP1
huntingtin interacting protein 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 52 entries
enrichment   p-value GO term description
1.48 2.18e-02 GO:0030029 actin filament-based process
1.47 2.67e-04 GO:0032583 regulation of gene-specific transcription
1.44 1.10e-02 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
1.39 8.28e-03 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.35 6.02e-03 GO:0051172 negative regulation of nitrogen compound metabolic process
1.35 1.78e-02 GO:0051253 negative regulation of RNA metabolic process
1.35 2.79e-02 GO:0045892 negative regulation of transcription, DNA-dependent
1.34 2.09e-03 GO:0010628 positive regulation of gene expression
1.34 3.59e-03 GO:0051254 positive regulation of RNA metabolic process
1.33 1.18e-02 GO:0045893 positive regulation of transcription, DNA-dependent
1.33 1.41e-02 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.33 1.60e-02 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.32 4.30e-05 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.32 2.23e-02 GO:0010558 negative regulation of macromolecule biosynthetic process
1.32 3.22e-02 GO:0010629 negative regulation of gene expression
1.31 2.67e-02 GO:0031327 negative regulation of cellular biosynthetic process
1.30 9.07e-03 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.30 9.89e-03 GO:0051173 positive regulation of nitrogen compound metabolic process
1.30 3.77e-02 GO:0009890 negative regulation of biosynthetic process
1.29 2.93e-03 GO:0022008 neurogenesis

Gene overrepresentation in compartment category:

Showing 1 to 5 of 5 entries
enrichment   p-value GO term description
1.87 1.18e-02 GO:0033267 axon part
1.35 2.51e-02 GO:0043005 neuron projection
1.14 2.16e-02 GO:0044459 plasma membrane part
1.10 6.30e-03 GO:0071944 cell periphery
1.10 1.07e-02 GO:0005886 plasma membrane

Gene overrepresentation in function category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
1.42 2.07e-02 GO:0016563 transcription activator activity
1.34 4.29e-04 GO:0043565 sequence-specific DNA binding
1.31 2.95e-02 GO:0008092 cytoskeletal protein binding
1.29 6.87e-05 GO:0030528 transcription regulator activity
1.27 6.21e-04 GO:0001071 nucleic acid binding transcription factor activity
1.27 6.21e-04 GO:0003700 sequence-specific DNA binding transcription factor activity
1.09 5.60e-05 GO:0005515 protein binding