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Motif ID: KLF12.p2

Z-value: 3.068

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr16_-_66535923	3.490		SLC12A4	solute carrier family 12 (potassium/chloride transporters), member 4
chr9_+_136673464	2.806	NM_000093	COL5A1	collagen, type V, alpha 1
chr3_-_130761967	2.658		PLXND1	plexin D1
chr16_-_66535457	2.465	NM_000229	LCAT	lecithin-cholesterol acyltransferase
chr17_+_1580504	2.446		WDR81	WD repeat domain 81
chr16_+_31132842	2.411	NM_001008274	TRIM72	tripartite motif containing 72
chr2_+_85834111	2.194	NM_032827	ATOH8	atonal homolog 8 (Drosophila)
chr7_+_149699185	1.939	NM_014374	REPIN1	replication initiator 1
chrX_+_152699616	1.910	NM_001170760 NM_001170761 NM_014370	SRPK3	SRSF protein kinase 3
chr9_+_136673534	1.888		COL5A1	collagen, type V, alpha 1
chr15_+_38550451	1.830	NM_130468	CHST14	carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14
chr5_+_34692239	1.807		RAI14	retinoic acid induced 14
chr16_+_82490230	1.735	NM_012213	MLYCD	malonyl-CoA decarboxylase
chr7_-_27180398	1.706	NM_018951	HOXA10	homeobox A10
chr16_+_27320983	1.696	NM_181078 NM_181079	IL21R	interleukin 21 receptor
chr13_-_110365336	1.661		ANKRD10	ankyrin repeat domain 10
chr5_+_34692352	1.651	NM_001145520	RAI14	retinoic acid induced 14
chr4_+_2783764	1.610		SH3BP2	SH3-domain binding protein 2
chr2_-_219791902	1.590	NM_005689	ABCB6	ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr7_-_75206152	1.576		HIP1	huntingtin interacting protein 1
chr11_-_118716244	1.549		MFRP	membrane frizzled-related protein
chr2_-_219791638	1.516		ABCB6	ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr11_+_116575249	1.502	NM_001001522 NM_003186	TAGLN	transgelin
chr2_-_220144254	1.501		OBSL1	obscurin-like 1
chr20_-_3713509	1.496		CENPB	centromere protein B, 80kDa
chr17_+_1612092	1.488		SERPINF1	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr7_-_75206212	1.478	NM_005338	HIP1	huntingtin interacting protein 1
chr5_+_155686333	1.444	NM_000337 NM_001128209 NM_172244	SGCD	sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
chr17_+_35853177	1.404	NM_001552	IGFBP4	insulin-like growth factor binding protein 4
chr5_+_34692124	1.391	NM_001145522 NM_015577	RAI14	retinoic acid induced 14
chr20_+_30409649	1.389	NM_001164603 NM_015338	ASXL1	additional sex combs like 1 (Drosophila)
chr12_-_79855580	1.385		LIN7A	lin-7 homolog A (C. elegans)
chr1_-_201411533	1.355	NM_004997	MYBPH	myosin binding protein H
chr10_+_76256305	1.353	NM_012330	MYST4	MYST histone acetyltransferase (monocytic leukemia) 4
chr1_+_168899936	1.351	NM_006902 NM_022716	PRRX1	paired related homeobox 1
chr2_+_170074457	1.344	NM_006063	KBTBD10	kelch repeat and BTB (POZ) domain containing 10
chr9_+_139292094	1.340	NM_017723	C9orf167	chromosome 9 open reading frame 167
chr17_+_1612056	1.301		SERPINF1	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr19_-_50688310	1.298	NM_206901	RTN2	reticulon 2
chr17_-_44026042	1.290	NM_002147	HOXB5	homeobox B5
chr17_-_45620911	1.278		COL1A1	collagen, type I, alpha 1
chr12_+_56135353	1.236	NM_031479	INHBE	inhibin, beta E
chr17_-_44026321	1.232		HOXB5	homeobox B5
chr12_-_79855618	1.221	NM_004664	LIN7A	lin-7 homolog A (C. elegans)
chr5_-_81082614	1.218		SSBP2	single-stranded DNA binding protein 2
chr17_+_1612031	1.212		SERPINF1	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr19_+_40322231	1.208	NM_005031	FXYD1	FXYD domain containing ion transport regulator 1
chr6_+_116939500	1.189	NM_153711	FAM26E	family with sequence similarity 26, member E
chr15_-_80123935	1.184		MEX3B	mex-3 homolog B (C. elegans)
chr16_-_71639670	1.171	NM_006885	ZFHX3	zinc finger homeobox 3
chr1_+_26671488	1.170	NM_005517	HMGN2	high-mobility group nucleosomal binding domain 2
chr10_+_94439658	1.166	NM_002729	HHEX	hematopoietically expressed homeobox
chr3_+_49033621	1.164	NM_199073	NDUFAF3	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 3
chr10_-_105410840	1.164
chr17_-_35331435	1.139		ORMDL3	ORM1-like 3 (S. cerevisiae)
chr12_+_79625538	1.130	NM_002469	MYF6	myogenic factor 6 (herculin)
chr19_-_46504831	1.124
chr5_-_81082699	1.117	NM_012446	SSBP2	single-stranded DNA binding protein 2
chr2_-_220144427	1.107		OBSL1	obscurin-like 1
chr1_+_26895108	1.107	NM_006015 NM_139135	ARID1A	AT rich interactive domain 1A (SWI-like)
chr4_-_111777651	1.104		PITX2	paired-like homeodomain 2
chr19_-_11169457	1.096		KANK2	KN motif and ankyrin repeat domains 2
chr15_-_72952648	1.094	NM_005697	SCAMP2	secretory carrier membrane protein 2
chr4_-_111777584	1.076		PITX2	paired-like homeodomain 2
chr17_-_34607257	1.071	NM_000723 NM_199247 NM_199248	CACNB1	calcium channel, voltage-dependent, beta 1 subunit
chr20_+_34603311	1.069		MYL9	myosin, light chain 9, regulatory
chr10_+_104394185	1.063	NM_030912	TRIM8	tripartite motif containing 8
chr16_+_2503676	1.063	NM_001198569 NM_001694	ATP6V0C	ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
chr13_-_110365416	1.057	NM_017664	ANKRD10	ankyrin repeat domain 10
chr11_+_67534371	1.049		ALDH3B1	aldehyde dehydrogenase 3 family, member B1
chr7_+_37926943	1.048		EPDR1	ependymin related protein 1 (zebrafish)
chr2_-_220144511	1.039	NM_001173408 NM_001173431 NM_015311	OBSL1	obscurin-like 1
chr19_+_43572679	1.033	NM_001039616 NM_001042522	SPRED3	sprouty-related, EVH1 domain containing 3
chr1_+_244954153	1.024		SCCPDH	saccharopine dehydrogenase (putative)
chr3_-_169295752	1.021		GOLIM4	golgi integral membrane protein 4
chr16_+_2503915	1.017		ATP6V0C	ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
chr3_+_49034050	0.995	NM_199069 NM_199070	NDUFAF3	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 3
chr5_+_175725050	0.987	NM_173664	ARL10	ADP-ribosylation factor-like 10
chr19_-_50975603	0.972	NM_001081563	DMPK	dystrophia myotonica-protein kinase
chr5_-_176857158	0.970		PDLIM7	PDZ and LIM domain 7 (enigma)
chr13_-_73606362	0.968		KLF12	Kruppel-like factor 12
chr16_-_30301357	0.968		SEPT1	septin 1
chr4_-_111763356	0.963		PITX2	paired-like homeodomain 2
chr19_+_2427122	0.962	NM_015675	GADD45B	growth arrest and DNA-damage-inducible, beta
chr13_-_110365282	0.950
chr7_-_135083906	0.948	NM_205855	FAM180A	family with sequence similarity 180, member A
chr7_+_47661366	0.939	NM_001123065	C7orf65	chromosome 7 open reading frame 65
chr15_+_72397934	0.933	NM_182791	CCDC33	coiled-coil domain containing 33
chr2_+_169367345	0.930	NM_001039724 NM_001171632 NM_052946	NOSTRIN	nitric oxide synthase trafficker
chr1_-_201321711	0.923		MYOG	myogenin (myogenic factor 4)
chr16_-_30992574	0.922		ZNF668	zinc finger protein 668
chr17_-_45622064	0.918
chr6_+_17708483	0.914	NM_016255	FAM8A1	family with sequence similarity 8, member A1
chr17_+_71141108	0.909	NM_001162995	LOC643008	hypothetical protein LOC643008
chr5_-_176868483	0.903		DOK3	docking protein 3
chr16_+_7322751	0.901	NM_145891 NM_145892 NM_145893	RBFOX1	RNA binding protein, fox-1 homolog (C. elegans) 1
chr11_+_65164767	0.898		SIPA1	signal-induced proliferation-associated 1
chr15_-_97366313	0.891	NM_001102612	PGPEP1L	pyroglutamyl-peptidase I-like
chr5_-_149515331	0.884		PDGFRB	platelet-derived growth factor receptor, beta polypeptide
chr1_+_6767968	0.882	NM_001195563 NM_015215	CAMTA1	calmodulin binding transcription activator 1
chr10_-_43464157	0.881	NM_001005368	ZNF32	zinc finger protein 32
chr4_+_129951877	0.879		PHF17	PHD finger protein 17
chr17_-_45620313	0.875
chr11_-_1974829	0.865		H19	H19, imprinted maternally expressed transcript (non-protein coding)
chr5_-_176857207	0.862	NM_005451 NM_203352 NM_213636	PDLIM7	PDZ and LIM domain 7 (enigma)
chr6_-_11490487	0.862	NM_001142393	NEDD9	neural precursor cell expressed, developmentally down-regulated 9
chr11_-_65841077	0.859	NM_020404	CD248	CD248 molecule, endosialin
chr20_+_2769338	0.854	NM_022575 NM_080413	VPS16	vacuolar protein sorting 16 homolog (S. cerevisiae)
chr5_+_155686750	0.851		SGCD	sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
chr20_-_2769245	0.850	NM_022760	FAM113A	family with sequence similarity 113, member A
chr2_-_73152323	0.840	NM_144579	SFXN5	sideroflexin 5
chr3_-_121883647	0.833		HGD	homogentisate 1,2-dioxygenase
chr15_+_72005864	0.831		LOXL1	lysyl oxidase-like 1
chr3_+_46423682	0.828	NM_003965 NM_001130910	CCRL2	chemokine (C-C motif) receptor-like 2
chr7_+_151792052	0.824		LOC100128822	hypothetical LOC100128822
chr20_-_2769120	0.822		FAM113A	family with sequence similarity 113, member A
chr6_-_110843432	0.815	NM_003649 NM_004032	DDO	D-aspartate oxidase
chr11_+_67534364	0.815	NM_000694 NM_001030010	ALDH3B1	aldehyde dehydrogenase 3 family, member B1
chr1_-_46370837	0.808	NM_003629 NM_001114172	PIK3R3	phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
chr16_+_2450081	0.806	NM_025108	C16orf59	chromosome 16 open reading frame 59
chr14_-_60185659	0.806	NM_005982	SIX1	SIX homeobox 1
chr16_-_30301634	0.804	NM_052838	SEPT1	septin 1
chr5_+_152850276	0.804	NM_000827 NM_001114183	GRIA1	glutamate receptor, ionotropic, AMPA 1
chr1_-_154205675	0.803		ARHGEF2	Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr17_+_1611983	0.799	NM_002615	SERPINF1	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr8_+_1936549	0.798		KBTBD11	kelch repeat and BTB (POZ) domain containing 11
chr11_+_65164963	0.797
chr20_-_2769789	0.796		FAM113A	family with sequence similarity 113, member A
chr15_+_72005875	0.796		LOXL1	lysyl oxidase-like 1
chr13_-_94751573	0.792	NM_001105515 NM_005845	ABCC4	ATP-binding cassette, sub-family C (CFTR/MRP), member 4
chr7_-_27191287	0.792	NM_005523	HOXA11	homeobox A11
chr5_-_176869463	0.791	NM_024872	DOK3	docking protein 3
chr22_+_19239221	0.791		MED15	mediator complex subunit 15
chr19_-_19487237	0.791	NM_032037	TSSK6	testis-specific serine kinase 6
chr19_+_55045754	0.791		PTOV1	prostate tumor overexpressed 1
chr4_-_1980473	0.790		WHSC2	Wolf-Hirschhorn syndrome candidate 2
chr3_-_129690056	0.784	NM_001145661	GATA2	GATA binding protein 2
chr14_+_102870431	0.783		EIF5	eukaryotic translation initiation factor 5
chr11_+_120966280	0.780		SORL1	sortilin-related receptor, L(DLR class) A repeats containing
chr9_+_135232937	0.780		C9orf96	chromosome 9 open reading frame 96
chr7_+_149657810	0.779	NM_138434	C7orf29	chromosome 7 open reading frame 29
chr16_+_2959362	0.778		PAQR4	progestin and adipoQ receptor family member IV
chr15_+_87540238	0.777		ABHD2	abhydrolase domain containing 2
chr10_-_118491971	0.773	NM_025015	HSPA12A	heat shock 70kDa protein 12A
chr11_-_118716736	0.773		C1QTNF5 MFRP	C1q and tumor necrosis factor related protein 5 membrane frizzled-related protein
chr17_-_59131210	0.772	NM_030576	LIMD2	LIM domain containing 2
chr11_+_17697685	0.769	NM_002478	MYOD1	myogenic differentiation 1
chr8_-_80842452	0.765	NM_001040708 NM_012258	HEY1	hairy/enhancer-of-split related with YRPW motif 1
chr17_-_45629401	0.764
chr11_+_66381451	0.761	NM_024036	LRFN4	leucine rich repeat and fibronectin type III domain containing 4
chr5_-_176869943	0.760	NM_001144875 NM_001144876	DOK3	docking protein 3
chr9_-_16717887	0.759		BNC2	basonuclin 2
chr6_+_31838751	0.758	NM_001039651	C6orf26	chromosome 6 open reading frame 26
chr5_-_32480486	0.755		ZFR	zinc finger RNA binding protein
chr17_-_59131194	0.753		LIMD2	LIM domain containing 2
chr9_-_138378061	0.752	NM_001080849	DNLZ	DNL-type zinc finger
chr1_+_23990228	0.750	NM_007260	LYPLA2	lysophospholipase II
chr4_-_176970407	0.750		GPM6A	glycoprotein M6A
chr3_+_45611180	0.749	NM_014240	LIMD1	LIM domains containing 1
chr19_+_16296734	0.746		KLF2	Kruppel-like factor 2 (lung)
chr15_-_72513311	0.744	NM_001146029 NM_003612	SEMA7A	semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
chr17_+_43127628	0.740	NM_014726	TBKBP1	TBK1 binding protein 1
chr11_-_1974992	0.740		H19	H19, imprinted maternally expressed transcript (non-protein coding)
chr1_-_201321999	0.739	NM_002479	MYOG	myogenin (myogenic factor 4)
chr9_-_138387903	0.735		CARD9	caspase recruitment domain family, member 9
chr20_+_34603290	0.731	NM_006097 NM_181526	MYL9	myosin, light chain 9, regulatory
chr4_-_176970895	0.731		GPM6A	glycoprotein M6A
chr5_-_78317444	0.728	NM_198709	ARSB	arylsulfatase B
chr4_-_165523856	0.725	NM_001166373	MARCH1	membrane-associated ring finger (C3HC4) 1
chr6_-_166716353	0.725		BRP44L	brain protein 44-like
chr9_+_35528628	0.724	NM_001135999	RUSC2	RUN and SH3 domain containing 2
chr11_-_117589283	0.724	NM_153206	AMICA1	adhesion molecule, interacts with CXADR antigen 1
chr10_-_94323808	0.722		IDE	insulin-degrading enzyme
chr16_+_30951915	0.719		STX4	syntaxin 4
chr10_-_43464272	0.717	NM_006973	ZNF32	zinc finger protein 32
chr6_+_11646472	0.716	NM_001100829	TMEM170B	transmembrane protein 170B
chr19_-_2378530	0.716		TIMM13	translocase of inner mitochondrial membrane 13 homolog (yeast)
chr14_+_57835028	0.713		ARID4A	AT rich interactive domain 4A (RBP1-like)
chr2_+_232281491	0.713		PTMA	prothymosin, alpha
chr1_-_32479785	0.712		MTMR9LP	myotubularin related protein 9-like, pseudogene
chr9_-_138880530	0.712	NM_003792 NM_153200	EDF1	endothelial differentiation-related factor 1
chr2_+_177965734	0.710		AGPS	alkylglycerone phosphate synthase
chr2_+_219991342	0.708	NM_001927	DES	desmin
chr1_+_52840630	0.707	NM_015696	GPX6 GPX7	glutathione peroxidase 6 (olfactory) glutathione peroxidase 7
chr16_+_2959342	0.707	NM_152341	PAQR4	progestin and adipoQ receptor family member IV
chr19_-_62680703	0.704	NM_001024596 NM_001144068	ZNF772	zinc finger protein 772
chr3_-_49033430	0.704	NM_018114	DALRD3	DALR anticodon binding domain containing 3
chr16_-_31427130	0.701	NM_022744	C16orf58	chromosome 16 open reading frame 58
chr2_+_56265260	0.699
chr1_+_26671548	0.698		HMGN2	high-mobility group nucleosomal binding domain 2
chr2_-_25328452	0.697	NM_153759	DNMT3A	DNA (cytosine-5-)-methyltransferase 3 alpha
chr6_+_20510019	0.696	NM_001949	E2F3	E2F transcription factor 3
chr1_+_116744992	0.694		ATP1A1	ATPase, Na+/K+ transporting, alpha 1 polypeptide
chr5_+_137716169	0.692	NM_016604	KDM3B	lysine (K)-specific demethylase 3B
chr16_+_87765661	0.691	NM_004933	CDH15	cadherin 15, type 1, M-cadherin (myotubule)
chr8_-_27171852	0.689		STMN4	stathmin-like 4
chr17_-_1336073	0.688		MYO1C	myosin IC
chr10_-_94323827	0.686	NM_004969	IDE	insulin-degrading enzyme
chr1_+_226394589	0.685		GUK1	guanylate kinase 1
chr6_-_111911106	0.684	NM_002912	REV3L	REV3-like, catalytic subunit of DNA polymerase zeta (yeast)

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.17	6.35e-07	GO:0032502	developmental process
1.17	1.16e-06	GO:0007275	multicellular organismal development
1.10	1.37e-06	GO:0065007	biological regulation
1.20	3.11e-06	GO:0048518	positive regulation of biological process
1.13	3.61e-06	GO:0032501	multicellular organismal process
1.18	3.75e-06	GO:0048856	anatomical structure development
1.10	5.59e-06	GO:0050789	regulation of biological process
1.19	5.98e-06	GO:0048731	system development
1.10	9.09e-06	GO:0050794	regulation of cellular process
1.27	1.81e-05	GO:0007399	nervous system development
1.19	4.06e-05	GO:0048522	positive regulation of cellular process
1.32	4.30e-05	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.14	2.28e-04	GO:0023052	signaling
1.47	2.67e-04	GO:0032583	regulation of gene-specific transcription
1.20	3.19e-04	GO:0048523	negative regulation of cellular process
1.20	6.41e-04	GO:0030154	cell differentiation
1.18	1.18e-03	GO:0048519	negative regulation of biological process
1.19	1.36e-03	GO:0048869	cellular developmental process
1.34	2.09e-03	GO:0010628	positive regulation of gene expression
1.29	2.93e-03	GO:0022008	neurogenesis
1.19	3.46e-03	GO:0048583	regulation of response to stimulus
1.34	3.59e-03	GO:0051254	positive regulation of RNA metabolic process
1.35	6.02e-03	GO:0051172	negative regulation of nitrogen compound metabolic process
1.20	7.04e-03	GO:0023051	regulation of signaling
1.19	7.73e-03	GO:0007166	cell surface receptor linked signaling pathway
1.39	8.28e-03	GO:0045944	positive regulation of transcription from RNA polymerase II promoter
1.30	9.07e-03	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.30	9.89e-03	GO:0051173	positive regulation of nitrogen compound metabolic process
1.28	1.00e-02	GO:0048699	generation of neurons
1.44	1.10e-02	GO:0010551	regulation of gene-specific transcription from RNA polymerase II promoter
1.25	1.14e-02	GO:0010646	regulation of cell communication
1.33	1.18e-02	GO:0045893	positive regulation of transcription, DNA-dependent
1.16	1.36e-02	GO:0051252	regulation of RNA metabolic process
1.33	1.41e-02	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.13	1.51e-02	GO:0007165	signal transduction
1.33	1.60e-02	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
1.17	1.76e-02	GO:0065008	regulation of biological quality
1.35	1.78e-02	GO:0051253	negative regulation of RNA metabolic process
1.48	2.18e-02	GO:0030029	actin filament-based process
1.32	2.23e-02	GO:0010558	negative regulation of macromolecule biosynthetic process
1.05	2.47e-02	GO:0009987	cellular process
1.31	2.67e-02	GO:0031327	negative regulation of cellular biosynthetic process
1.35	2.79e-02	GO:0045892	negative regulation of transcription, DNA-dependent
1.20	2.80e-02	GO:0009653	anatomical structure morphogenesis
1.27	2.91e-02	GO:0009891	positive regulation of biosynthetic process
1.32	3.22e-02	GO:0010629	negative regulation of gene expression
1.21	3.49e-02	GO:0051239	regulation of multicellular organismal process
1.15	3.52e-02	GO:0010468	regulation of gene expression
1.30	3.77e-02	GO:0009890	negative regulation of biosynthetic process
1.28	4.19e-02	GO:0007267	cell-cell signaling
1.20	4.26e-02	GO:0009966	regulation of signal transduction
1.27	4.51e-02	GO:0031328	positive regulation of cellular biosynthetic process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.10	6.30e-03	GO:0071944	cell periphery
1.10	1.07e-02	GO:0005886	plasma membrane
1.87	1.18e-02	GO:0033267	axon part
1.14	2.16e-02	GO:0044459	plasma membrane part
1.35	2.51e-02	GO:0043005	neuron projection

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.09	5.60e-05	GO:0005515	protein binding
1.29	6.87e-05	GO:0030528	transcription regulator activity
1.34	4.29e-04	GO:0043565	sequence-specific DNA binding
1.27	6.21e-04	GO:0001071	nucleic acid binding transcription factor activity
1.27	6.21e-04	GO:0003700	sequence-specific DNA binding transcription factor activity
1.42	2.07e-02	GO:0016563	transcription activator activity
1.31	2.95e-02	GO:0008092	cytoskeletal protein binding