Motif ID: KLF4.p3

Z-value: 3.719


Transcription factors associated with KLF4.p3:

Gene SymbolEntrez IDGene Name
KLF4 9314 Kruppel-like factor 4 (gut)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
KLF4chr9_-_1092905280.692.8e-03Click!


Activity profile for motif KLF4.p3.

activity profile for motif KLF4.p3


Sorted Z-values histogram for motif KLF4.p3

Sorted Z-values for motif KLF4.p3



Network of associatons between targets according to the STRING database.



First level regulatory network of KLF4.p3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_32992131 8.076


chr19_-_6718417 7.906 NM_005490
SH2D3A
SH2 domain containing 3A
chr19_-_45888259 5.194 NM_004756
NUMBL
numb homolog (Drosophila)-like
chr5_-_16989371 5.008 NM_012334
MYO10
myosin X
chr8_-_99906944 4.516 NM_006281
STK3
serine/threonine kinase 3
chr8_+_1699276 4.421 NM_018941
CLN8
ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
chr17_-_37196463 4.413 NM_002230
NM_021991
JUP

junction plakoglobin

chr11_-_94603857 3.618 NM_144665
SESN3
sestrin 3
chr1_-_208046011 3.500 NM_006147
IRF6
interferon regulatory factor 6
chr8_-_127639647 3.433 FAM84B
family with sequence similarity 84, member B
chr5_-_9599157 3.430 NM_003966
SEMA5A
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr9_-_129371171 3.409 NM_022833
FAM129B
family with sequence similarity 129, member B
chr2_+_24153255 3.371 LOC375190
hypothetical protein LOC375190
chr9_-_129370954 3.314 FAM129B
family with sequence similarity 129, member B
chr18_-_50004458 3.230 MBD2
methyl-CpG binding domain protein 2
chr3_-_46710137 3.162 NM_001190707
NM_147129
ALS2CL

ALS2 C-terminal like

chr8_-_144887876 3.144 NM_198488
FAM83H
family with sequence similarity 83, member H
chr22_-_37062114 3.117 CSNK1E
casein kinase 1, epsilon
chr10_-_80875097 3.110 NM_153367
ZCCHC24
zinc finger, CCHC domain containing 24
chr19_+_54558798 3.054 NM_001197302
NM_001197301
NM_014419
DKKL1


dickkopf-like 1


chr20_-_56317894 2.969 PPP4R1L
protein phosphatase 4, regulatory subunit 1-like
chr3_-_52065130 2.961 NM_001947
DUSP7
dual specificity phosphatase 7
chrX_+_15666312 2.960 NM_007220
CA5B
carbonic anhydrase VB, mitochondrial
chr2_-_235070431 2.938 NM_005737
ARL4C
ADP-ribosylation factor-like 4C
chr7_-_27120015 2.918 HOXA3
homeobox A3
chr9_+_90193058 2.914 NM_006717
SPIN1
spindlin 1
chr17_+_9489578 2.773 NM_153210
USP43
ubiquitin specific peptidase 43
chr18_-_50004770 2.758 MBD2
methyl-CpG binding domain protein 2
chr16_-_65287967 2.727 NM_178818
NM_181521
CMTM4

CKLF-like MARVEL transmembrane domain containing 4

chr10_-_126839546 2.660 NM_001083914
CTBP2
C-terminal binding protein 2
chr18_+_19706979 2.648 NM_000227
NM_001127718
LAMA3

laminin, alpha 3

chr19_-_45663463 2.643 NM_000713
BLVRB
biliverdin reductase B (flavin reductase (NADPH))
chr4_+_85723080 2.641 NM_001263
CDS1
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
chr5_-_16989290 2.631 MYO10
myosin X
chr8_-_127639892 2.606 NM_174911
FAM84B
family with sequence similarity 84, member B
chr17_-_46553083 2.604 NM_001130528
NM_003971
SPAG9

sperm associated antigen 9

chr19_+_43447262 2.604 SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr1_+_26728846 2.598 RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr1_+_28458546 2.590 NM_031459
SESN2
sestrin 2
chr20_+_56318245 2.550 RAB22A
RAB22A, member RAS oncogene family
chr18_-_26935883 2.528 NM_004949
NM_024422
DSC2

desmocollin 2

chr11_+_384238 2.504 PKP3
plakophilin 3
chr19_+_61742111 2.486 NM_020828
ZFP28
zinc finger protein 28 homolog (mouse)
chr17_+_72789086 2.478 NM_001113491
SEPT9
septin 9
chr8_-_102031943 2.471 NM_001135702
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr17_+_19081267 2.453 NM_001102664
NM_014964
NM_148921
EPN2


epsin 2


chr22_+_36632242 2.451 NM_033386
MICALL1
MICAL-like 1
chr7_+_115926855 2.440 CAV2
caveolin 2
chr13_+_72531098 2.402 NM_001730
KLF5
Kruppel-like factor 5 (intestinal)
chr1_-_113059396 2.389 NM_005167
PPM1J
protein phosphatase, Mg2+/Mn2+ dependent, 1J
chr11_-_6212421 2.379 FAM160A2
family with sequence similarity 160, member A2
chr4_+_154606900 2.374 NM_001131007
NM_015196
KIAA0922

KIAA0922

chr2_+_238265617 2.372 LRRFIP1
leucine rich repeat (in FLII) interacting protein 1
chr8_+_144888275 2.355 LOC100128338
hypothetical LOC100128338
chr13_+_41520888 2.354 NM_152910
NM_178009
DGKH

diacylglycerol kinase, eta

chr11_-_6212449 2.343 FAM160A2
family with sequence similarity 160, member A2
chr2_+_178767317 2.334 NM_032523
OSBPL6
oxysterol binding protein-like 6
chr2_+_24153174 2.334


chr19_-_16868674 2.331 CPAMD8
C3 and PZP-like, alpha-2-macroglobulin domain containing 8
chr17_+_45488330 2.328 NM_002204
NM_005501
ITGA3

integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)

chr4_+_79691875 2.322 ANXA3
annexin A3
chr11_-_67329246 2.316 LOC645332
family with sequence similarity 86, member A pseudogene
chrX_-_134883798 2.312 NM_173470
MMGT1
membrane magnesium transporter 1
chr4_+_87734489 2.295 NM_006264
NM_080683
NM_080684
NM_080685
PTPN13



protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)



chr11_+_384199 2.291 NM_007183
PKP3
plakophilin 3
chr12_-_46585032 2.283 NM_000376
NM_001017535
VDR

vitamin D (1,25- dihydroxyvitamin D3) receptor

chr11_-_6451561 2.267 NM_006458
NM_033278
TRIM3

tripartite motif containing 3

chr21_+_32706615 2.248 NM_058187
C21orf63
chromosome 21 open reading frame 63
chr6_-_35572694 2.233 NM_003214
TEAD3
TEA domain family member 3
chr1_+_26728827 2.229 NM_002953
RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr20_+_56318415 2.227 RAB22A
RAB22A, member RAS oncogene family
chr3_+_137167296 2.225 PPP2R3A
protein phosphatase 2, regulatory subunit B'', alpha
chr1_-_85514580 2.216 BCL10
B-cell CLL/lymphoma 10
chr2_+_24152799 2.194


chr3_+_160964574 2.191 SCHIP1
schwannomin interacting protein 1
chr19_+_45807909 2.191


chr5_-_2804768 2.188 NM_001134222
NM_033267
IRX2

iroquois homeobox 2

chr18_+_59295123 2.186 NM_002639
SERPINB5
serpin peptidase inhibitor, clade B (ovalbumin), member 5
chr1_-_117011824 2.168 NM_001007237
NM_001542
IGSF3

immunoglobulin superfamily, member 3

chr1_+_26728839 2.166 RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr20_+_56318155 2.166 NM_020673
RAB22A
RAB22A, member RAS oncogene family
chrX_-_149817785 2.139 NM_001184808
NM_031462
NM_134445
NM_134446
CD99L2



CD99 molecule-like 2



chr17_+_24079924 2.137 NM_178170
NEK8
NIMA (never in mitosis gene a)- related kinase 8
chr17_-_17667580 2.135 SREBF1
sterol regulatory element binding transcription factor 1
chr8_+_1699418 2.132 CLN8
ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
chr1_+_182622987 2.130 C1orf21
chromosome 1 open reading frame 21
chr12_-_45759691 2.124 NM_001143668
NM_181847
AMIGO2

adhesion molecule with Ig-like domain 2

chr5_-_114660139 2.121 NM_001040440
CCDC112
coiled-coil domain containing 112
chr6_-_6632197 2.116


chr1_-_38243747 2.107 NM_004468
FHL3
four and a half LIM domains 3
chr13_-_109236897 2.097 NM_003749
IRS2
insulin receptor substrate 2
chr15_+_39907447 2.095 NM_001114632
NM_001198588
NM_005090
JMJD7
JMJD7-PLA2G4B

jumonji domain containing 7
JMJD7-PLA2G4B readthrough

chr11_-_6212467 2.089 NM_001098794
NM_032127
FAM160A2

family with sequence similarity 160, member A2

chr9_-_35101592 2.079 KIAA1539
KIAA1539
chr19_-_12747263 2.076 HOOK2
hook homolog 2 (Drosophila)
chr1_+_231530136 2.075 NM_032435
KIAA1804
mixed lineage kinase 4
chr19_-_6061491 2.066 RFX2
regulatory factor X, 2 (influences HLA class II expression)
chr9_-_109291575 2.064 KLF4
Kruppel-like factor 4 (gut)
chr22_-_17489718 2.061 DGCR2
DiGeorge syndrome critical region gene 2
chr19_+_60283571 2.055 NM_017729
EPS8L1
EPS8-like 1
chr8_-_145085616 2.053 NM_201384
PLEC
plectin
chr1_-_115060904 2.047 NRAS
neuroblastoma RAS viral (v-ras) oncogene homolog
chr15_-_58477407 2.045 NM_001002857
NM_001002858
NM_001136015
NM_004039
ANXA2



annexin A2



chr20_-_33329319 2.039 EDEM2
ER degradation enhancer, mannosidase alpha-like 2
chr5_+_96024434 2.038 CAST
calpastatin
chr12_+_8958397 2.034 NM_004426
PHC1
polyhomeotic homolog 1 (Drosophila)
chr12_+_51777715 2.028 IGFBP6
insulin-like growth factor binding protein 6
chr1_-_173428455 2.022 NM_001162895
NM_014656
NM_001162893
NM_001162894
KIAA0040



KIAA0040



chr2_-_9061193 2.018 NM_138799
MBOAT2
membrane bound O-acyltransferase domain containing 2
chr7_-_105712646 2.006 NM_005746
NAMPT
nicotinamide phosphoribosyltransferase
chr19_+_40298571 2.005 NM_001136007
NM_001136008
NM_001136009
NM_001136010
NM_001136011
NM_001136012
NM_005971
NM_021910
FXYD3







FXYD domain containing ion transport regulator 3







chr1_-_115060857 1.990 NRAS
neuroblastoma RAS viral (v-ras) oncogene homolog
chr8_+_142207866 1.988 NM_014957
DENND3
DENN/MADD domain containing 3
chr11_-_33678861 1.969 NM_001166692
C11orf91
chromosome 11 open reading frame 91
chr19_+_53520632 1.961 EMP3
epithelial membrane protein 3
chr1_-_150232927 1.952 S100A10
S100 calcium binding protein A10
chr1_-_38243716 1.947 FHL3
four and a half LIM domains 3
chrX_-_135161185 1.945 NM_001173517
NM_024597
MAP7D3

MAP7 domain containing 3

chr8_-_22044463 1.942 NM_005144
NM_018411
HR

hairless homolog (mouse)

chr12_-_102759098 1.941 NM_001031701
NT5DC3
5'-nucleotidase domain containing 3
chr8_-_134378630 1.940 NM_001135242
NM_006096
NDRG1

N-myc downstream regulated 1

chr2_-_17563186 1.931 NM_001099218
RAD51AP2
RAD51 associated protein 2
chr7_-_72771853 1.929 NM_001165903
NM_004603
STX1A

syntaxin 1A (brain)

chr2_-_175060001 1.926 NM_001033045
NM_152529
GPR155

G protein-coupled receptor 155

chr8_+_94998258 1.924 NM_018444
NM_001161780
NM_001161779
NM_001161781
PDP1



pyruvate dehyrogenase phosphatase catalytic subunit 1



chr2_+_10101081 1.906 NM_003597
NM_001177716
KLF11

Kruppel-like factor 11

chr19_-_6061561 1.898 NM_000635
NM_134433
RFX2

regulatory factor X, 2 (influences HLA class II expression)

chr21_-_36450448 1.893 LOC100506428
hypothetical LOC100506428
chr11_-_64368616 1.885 NM_017525
CDC42BPG
CDC42 binding protein kinase gamma (DMPK-like)
chr18_+_3439972 1.879 NM_173209
NM_173208
NM_003244
TGIF1


TGFB-induced factor homeobox 1


chr11_-_56848859 1.872 NM_033396
TNKS1BP1
tankyrase 1 binding protein 1, 182kDa
chrX_-_149817720 1.865 CD99L2
CD99 molecule-like 2
chr2_+_241023703 1.857 NM_002081
GPC1
glypican 1
chr19_+_50535837 1.853 NM_177417
KLC3
kinesin light chain 3
chr17_+_30938391 1.844 NM_001030006
NM_001282
AP2B1

adaptor-related protein complex 2, beta 1 subunit

chr17_+_45488356 1.836 ITGA3
integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
chr19_-_51856129 1.833 NM_145056
DACT3
dapper, antagonist of beta-catenin, homolog 3 (Xenopus laevis)
chr3_+_137167153 1.833 NM_001190447
NM_002718
PPP2R3A

protein phosphatase 2, regulatory subunit B'', alpha

chr22_+_27798887 1.819 NM_001039570
NM_032045
KREMEN1

kringle containing transmembrane protein 1

chr1_+_201862548 1.818 NM_001001396
NM_001684
ATP2B4

ATPase, Ca++ transporting, plasma membrane 4

chr17_+_77582774 1.815 NM_005052
RAC3
ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
chr22_-_37520092 1.800 NM_005740
DNAL4
dynein, axonemal, light chain 4
chr6_-_136913235 1.797 MAP7
microtubule-associated protein 7
chr14_-_104515738 1.794 NM_138420
AHNAK2
AHNAK nucleoprotein 2
chr12_-_32940931 1.785 NM_001005242
NM_004572
PKP2

plakophilin 2

chr4_-_125853166 1.782 NM_001167882
NM_020337
ANKRD50

ankyrin repeat domain 50

chr12_-_28014151 1.781 NM_198964
NM_198966
PTHLH

parathyroid hormone-like hormone

chr1_-_167603623 1.778 NM_013330
NM_197972
NME7

non-metastatic cells 7, protein expressed in (nucleoside-diphosphate kinase)

chr5_-_1935764 1.777 NM_016358
IRX4
iroquois homeobox 4
chr1_+_891739 1.770 NM_001160184
NM_032129
PLEKHN1

pleckstrin homology domain containing, family N member 1

chr1_+_24701886 1.768 NM_013441
RCAN3
RCAN family member 3
chr17_+_30938433 1.768 AP2B1
adaptor-related protein complex 2, beta 1 subunit
chr7_+_16759845 1.766 NM_014399
TSPAN13
tetraspanin 13
chr17_-_24973940 1.751 CORO6
coronin 6
chr5_+_96023926 1.750 CAST
calpastatin
chr3_-_48607596 1.721 NM_000094
COL7A1
collagen, type VII, alpha 1
chr9_-_35101534 1.719 KIAA1539
KIAA1539
chr12_-_119187871 1.718 PXN
paxillin
chr8_+_32525269 1.711 NM_001160002
NM_001160004
NM_001160005
NM_001160007
NM_001160008
NM_004495
NM_013956
NM_013957
NM_013958
NM_013960
NM_013964
NRG1










neuregulin 1










chr5_+_2805261 1.708 NM_178569
C5orf38
chromosome 5 open reading frame 38
chr19_+_7891884 1.707 SNAPC2
small nuclear RNA activating complex, polypeptide 2, 45kDa
chr7_-_150305933 1.702 NM_000238
NM_172056
KCNH2

potassium voltage-gated channel, subfamily H (eag-related), member 2

chr2_-_158440587 1.698 NM_001111067
ACVR1
activin A receptor, type I
chr12_+_51777684 1.697 NM_002178
IGFBP6
insulin-like growth factor binding protein 6
chr7_-_97868101 1.695 BAIAP2L1
BAI1-associated protein 2-like 1
chr16_+_65790514 1.695 NM_024712
ELMO3
engulfment and cell motility 3
chr2_+_235525355 1.695 NM_014521
SH3BP4
SH3-domain binding protein 4
chr1_-_150276091 1.679 S100A11
S100 calcium binding protein A11
chr17_-_78199384 1.666 NM_019613
WDR45L
WDR45-like
chr7_+_100302885 1.648 NM_003302
TRIP6
thyroid hormone receptor interactor 6
chr1_-_201043000 1.642 KDM5B
lysine (K)-specific demethylase 5B
chr11_+_44543716 1.626 NM_001024844
NM_002231
CD82

CD82 molecule

chr1_+_44230011 1.624 CCDC24
coiled-coil domain containing 24
chr1_+_205561439 1.623 NM_000574
NM_001114752
CD55

CD55 molecule, decay accelerating factor for complement (Cromer blood group)

chr9_+_129962292 1.612 NM_024112
C9orf16
chromosome 9 open reading frame 16
chr11_+_44543788 1.610 CD82
CD82 molecule
chrX_+_48915127 1.609 NM_002668
PLP2
proteolipid protein 2 (colonic epithelium-enriched)
chr7_-_127837242 1.606 NM_000883
NM_001102605
NM_001142576
NM_183243
IMPDH1



IMP (inosine 5'-monophosphate) dehydrogenase 1



chr6_-_42527760 1.598 NM_033502
TRERF1
transcriptional regulating factor 1
chr12_-_53071285 1.597 NM_001130967
NM_001130968
ZNF385A

zinc finger protein 385A

chr19_-_48977247 1.593 NM_002250
KCNN4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr22_-_17489912 1.592 NM_001173533
NM_001173534
NM_001184781
NM_005137
DGCR2



DiGeorge syndrome critical region gene 2



chr1_-_115014151 1.590 NM_198459
DENND2C
DENN/MADD domain containing 2C
chr6_+_35528127 1.590 FANCE
Fanconi anemia, complementation group E
chr19_+_43447078 1.588 SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr15_+_61356801 1.586 NM_001145646
NM_031301
APH1B

anterior pharynx defective 1 homolog B (C. elegans)

chr10_+_75427853 1.576 NM_003373
NM_014000
VCL

vinculin

chr10_+_112247614 1.575 NM_004419
DUSP5
dual specificity phosphatase 5
chrX_+_17303270 1.572 NHS
Nance-Horan syndrome (congenital cataracts and dental anomalies)
chr1_+_210672817 1.568 NM_013349
NENF
neuron derived neurotrophic factor
chr16_+_31036474 1.557 NM_032188
NM_182958
MYST1

MYST histone acetyltransferase 1

chr19_-_48976852 1.550 KCNN4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr3_-_125085834 1.548 NM_053025
NM_053026
NM_053027
NM_053028
MYLK



myosin light chain kinase



chr7_+_79602023 1.547 NM_002069
GNAI1
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
chr19_+_53520439 1.542 NM_001425
EMP3
epithelial membrane protein 3
chr12_-_53099203 1.538 ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr18_+_55718171 1.535 NM_021127
PMAIP1
phorbol-12-myristate-13-acetate-induced protein 1
chr1_+_30964199 1.531 LOC100129196
hypothetical LOC100129196
chr7_+_115953582 1.529 NM_001172896
NM_001172897
CAV1

caveolin 1, caveolae protein, 22kDa

chr11_+_12088639 1.528 NM_014632
MICAL2
microtubule associated monoxygenase, calponin and LIM domain containing 2

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.07 2.36e-16 GO:0009987 cellular process
1.09 1.87e-12 GO:0050789 regulation of biological process
1.09 7.03e-12 GO:0050794 regulation of cellular process
1.09 8.19e-12 GO:0065007 biological regulation
1.09 1.86e-09 GO:0044237 cellular metabolic process
1.12 4.19e-09 GO:0044260 cellular macromolecule metabolic process
1.18 6.58e-07 GO:0006464 protein modification process
1.08 7.85e-07 GO:0044238 primary metabolic process
1.12 1.30e-06 GO:0023052 signaling
1.09 3.96e-06 GO:0043170 macromolecule metabolic process
1.12 6.90e-06 GO:0016043 cellular component organization
1.18 1.09e-05 GO:0023051 regulation of signaling
1.07 1.73e-05 GO:0008152 metabolic process
1.18 1.81e-05 GO:0007399 nervous system development
1.16 1.96e-05 GO:0043412 macromolecule modification
1.11 4.05e-05 GO:0071840 cellular component organization or biogenesis
1.33 4.32e-05 GO:0048667 cell morphogenesis involved in neuron differentiation
1.11 5.62e-05 GO:0031323 regulation of cellular metabolic process
1.33 5.63e-05 GO:0048812 neuron projection morphogenesis
1.18 6.67e-05 GO:0009653 anatomical structure morphogenesis
1.31 7.89e-05 GO:0031175 neuron projection development
1.21 7.98e-05 GO:0006793 phosphorus metabolic process
1.21 7.98e-05 GO:0006796 phosphate metabolic process
1.23 8.43e-05 GO:0048699 generation of neurons
1.13 8.81e-05 GO:0071842 cellular component organization at cellular level
1.45 9.53e-05 GO:0048011 nerve growth factor receptor signaling pathway
1.13 1.18e-04 GO:0048519 negative regulation of biological process
1.26 1.18e-04 GO:0030182 neuron differentiation
1.33 1.48e-04 GO:0007409 axonogenesis
1.10 1.58e-04 GO:0019222 regulation of metabolic process
1.11 1.82e-04 GO:0007165 signal transduction
1.13 2.34e-04 GO:0044267 cellular protein metabolic process
1.17 2.74e-04 GO:0009966 regulation of signal transduction
1.14 2.92e-04 GO:0048523 negative regulation of cellular process
1.12 3.26e-04 GO:0048518 positive regulation of biological process
1.12 4.76e-04 GO:0071841 cellular component organization or biogenesis at cellular level
1.29 4.90e-04 GO:0000904 cell morphogenesis involved in differentiation
1.21 6.46e-04 GO:0022008 neurogenesis
1.25 7.89e-04 GO:0030030 cell projection organization
1.17 8.73e-04 GO:0035556 intracellular signal transduction
1.09 1.26e-03 GO:0051716 cellular response to stimulus
1.10 1.29e-03 GO:0006807 nitrogen compound metabolic process
1.12 1.32e-03 GO:0048522 positive regulation of cellular process
1.26 1.85e-03 GO:0048666 neuron development
1.11 1.87e-03 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.27 2.05e-03 GO:0032990 cell part morphogenesis
1.27 2.13e-03 GO:0048858 cell projection morphogenesis
1.21 2.28e-03 GO:0033554 cellular response to stress
1.09 3.00e-03 GO:0080090 regulation of primary metabolic process
1.10 3.87e-03 GO:0034641 cellular nitrogen compound metabolic process
1.22 4.46e-03 GO:0006468 protein phosphorylation
1.23 5.03e-03 GO:0007167 enzyme linked receptor protein signaling pathway
1.37 5.94e-03 GO:0000165 MAPKKK cascade
1.20 6.66e-03 GO:0016310 phosphorylation
1.09 7.50e-03 GO:0060255 regulation of macromolecule metabolic process
1.78 1.58e-02 GO:0051403 stress-activated MAPK cascade
1.22 1.72e-02 GO:0032989 cellular component morphogenesis
1.10 1.91e-02 GO:0019538 protein metabolic process
1.30 2.03e-02 GO:0007411 axon guidance
1.08 2.14e-02 GO:0032502 developmental process
1.23 2.45e-02 GO:0000902 cell morphogenesis
1.18 2.94e-02 GO:0006351 transcription, DNA-dependent
1.18 3.42e-02 GO:0048468 cell development
1.10 3.61e-02 GO:0031326 regulation of cellular biosynthetic process
1.30 3.61e-02 GO:0051347 positive regulation of transferase activity
1.10 3.84e-02 GO:0051171 regulation of nitrogen compound metabolic process
1.24 3.98e-02 GO:0051338 regulation of transferase activity
1.08 4.18e-02 GO:0051179 localization
1.18 4.22e-02 GO:0016265 death
1.17 4.34e-02 GO:0042981 regulation of apoptosis
1.18 4.44e-02 GO:0008219 cell death
1.24 4.66e-02 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.20 4.82e-02 GO:0009790 embryo development

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.08 2.81e-31 GO:0005622 intracellular
1.08 1.43e-30 GO:0044424 intracellular part
1.11 1.62e-24 GO:0005737 cytoplasm
1.09 6.57e-22 GO:0043226 organelle
1.09 9.84e-22 GO:0043229 intracellular organelle
1.09 1.19e-19 GO:0043227 membrane-bounded organelle
1.09 1.25e-19 GO:0043231 intracellular membrane-bounded organelle
1.12 6.99e-18 GO:0044444 cytoplasmic part
1.10 3.52e-10 GO:0044446 intracellular organelle part
1.10 3.85e-10 GO:0005634 nucleus
1.10 8.76e-10 GO:0044422 organelle part
1.17 3.70e-08 GO:0005829 cytosol
1.02 3.64e-07 GO:0044464 cell part
1.02 4.09e-07 GO:0005623 cell
1.18 9.18e-07 GO:0012505 endomembrane system
1.15 3.49e-06 GO:0031090 organelle membrane
1.20 4.18e-05 GO:0005794 Golgi apparatus
1.10 4.59e-04 GO:0043234 protein complex
1.14 1.02e-03 GO:0005856 cytoskeleton
1.12 1.05e-03 GO:0044428 nuclear part
1.13 1.54e-03 GO:0031981 nuclear lumen
1.23 2.04e-03 GO:0030054 cell junction
1.31 4.38e-03 GO:0015629 actin cytoskeleton
1.10 5.93e-03 GO:0043228 non-membrane-bounded organelle
1.10 5.93e-03 GO:0043232 intracellular non-membrane-bounded organelle
1.26 6.55e-03 GO:0045202 synapse
1.20 9.38e-03 GO:0015630 microtubule cytoskeleton
1.17 2.08e-02 GO:0005626 insoluble fraction
1.13 2.35e-02 GO:0005654 nucleoplasm
1.17 3.35e-02 GO:0005624 membrane fraction
1.27 4.49e-02 GO:0044456 synapse part
1.10 4.63e-02 GO:0070013 intracellular organelle lumen

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.13 5.23e-29 GO:0005515 protein binding
1.07 2.35e-24 GO:0005488 binding
1.14 5.14e-06 GO:0000166 nucleotide binding
1.15 2.45e-05 GO:0017076 purine nucleotide binding
1.15 2.80e-05 GO:0032553 ribonucleotide binding
1.15 2.80e-05 GO:0032555 purine ribonucleotide binding
1.14 1.46e-04 GO:0035639 purine ribonucleoside triphosphate binding
1.16 1.80e-04 GO:0030554 adenyl nucleotide binding
1.15 2.68e-04 GO:0032559 adenyl ribonucleotide binding
1.15 8.48e-04 GO:0005524 ATP binding
1.21 1.46e-03 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.20 1.63e-03 GO:0016301 kinase activity
1.18 3.04e-03 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.12 1.14e-02 GO:0016740 transferase activity
1.06 2.16e-02 GO:0003824 catalytic activity
1.16 2.70e-02 GO:0001071 nucleic acid binding transcription factor activity
1.16 2.70e-02 GO:0003700 sequence-specific DNA binding transcription factor activity