Motif ID: LMO2.p2

Z-value: 2.145


Transcription factors associated with LMO2.p2:

Gene SymbolEntrez IDGene Name
LMO2 4005 LIM domain only 2 (rhombotin-like 1)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
LMO2chr11_-_338704110.495.5e-02Click!


Activity profile for motif LMO2.p2.

activity profile for motif LMO2.p2


Sorted Z-values histogram for motif LMO2.p2

Sorted Z-values for motif LMO2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of LMO2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_3556420 2.953 NM_017818
WDR8
WD repeat domain 8
chr1_-_23729871 2.924 E2F2
E2F transcription factor 2
chr10_+_94598204 2.867 NM_019053
EXOC6
exocyst complex component 6
chr7_+_44754978 2.689 NM_031449
ZMIZ2
zinc finger, MIZ-type containing 2
chr22_+_23153529 2.620 NM_000675
ADORA2A
adenosine A2a receptor
chr16_-_87570716 2.613 NM_005187
CBFA2T3
core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr7_+_149696901 2.527 REPIN1
replication initiator 1
chr5_+_168996852 2.517 DOCK2
dedicator of cytokinesis 2
chr5_+_168996816 2.512 NM_004946
DOCK2
dedicator of cytokinesis 2
chr2_-_6923215 2.435 NM_207315
CMPK2
cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chr1_+_89763030 2.402 LRRC8B
leucine rich repeat containing 8 family, member B
chr10_+_92970302 2.389 NM_032373
PCGF5
polycomb group ring finger 5
chr1_+_89762984 2.318 NM_001134476
LRRC8B
leucine rich repeat containing 8 family, member B
chr19_+_5082230 2.261 KDM4B
lysine (K)-specific demethylase 4B
chr17_+_73676219 2.219 NM_004710
SYNGR2
synaptogyrin 2
chr2_+_222997529 2.218 NM_152386
SGPP2
sphingosine-1-phosphate phosphatase 2
chr1_+_90060131 2.209 LRRC8D
leucine rich repeat containing 8 family, member D
chr11_+_817584 2.203 NM_173584
EFCAB4A
EF-hand calcium binding domain 4A
chr1_+_90059992 2.199 NM_018103
LRRC8D
leucine rich repeat containing 8 family, member D
chr4_+_129951877 2.194 PHF17
PHD finger protein 17
chr2_+_222997456 2.103 SGPP2
sphingosine-1-phosphate phosphatase 2
chr5_-_176868483 2.081 DOK3
docking protein 3
chr22_+_35586950 2.009 NM_000631
NM_013416
NCF4

neutrophil cytosolic factor 4, 40kDa

chr1_+_12149637 1.987 NM_001066
TNFRSF1B
tumor necrosis factor receptor superfamily, member 1B
chr22_-_49317408 1.953 ODF3B
outer dense fiber of sperm tails 3B
chr3_-_13436802 1.943 NM_024923
NUP210
nucleoporin 210kDa
chr5_+_156625629 1.918 NM_001037333
NM_001037332
CYFIP2

cytoplasmic FMR1 interacting protein 2

chr5_+_95093267 1.867


chr1_+_12149662 1.862 TNFRSF1B
tumor necrosis factor receptor superfamily, member 1B
chr16_-_30301357 1.853 SEPT1
septin 1
chr22_-_20314274 1.816 NM_001017964
YDJC
YdjC homolog (bacterial)
chr10_+_92970487 1.797 PCGF5
polycomb group ring finger 5
chr17_-_18890963 1.785 NM_006613
GRAP
GRB2-related adaptor protein
chr17_-_8809656 1.769 NM_001142633
PIK3R5
phosphoinositide-3-kinase, regulatory subunit 5
chr11_+_63864263 1.730 NM_032251
CCDC88B
coiled-coil domain containing 88B
chr13_+_77170470 1.692 NM_001040153
SLAIN1
SLAIN motif family, member 1
chr9_-_139084833 1.691 NM_178448
C9orf140
chromosome 9 open reading frame 140
chr17_-_36559579 1.674 NM_033188
KRTAP4-5
keratin associated protein 4-5
chr6_+_11646472 1.624 NM_001100829
TMEM170B
transmembrane protein 170B
chr1_+_90059183 1.622 LRRC8D
leucine rich repeat containing 8 family, member D
chr14_+_71468902 1.621 RGS6
regulator of G-protein signaling 6
chr4_+_39874921 1.614 NM_004310
RHOH
ras homolog gene family, member H
chr17_-_4831388 1.610 NM_001171167
NM_001171168
CAMTA2

calmodulin binding transcription activator 2

chr1_-_23730298 1.580 NM_004091
E2F2
E2F transcription factor 2
chr19_-_60587414 1.579 NM_001190764
LOC388564
hypothetical protein LOC388564
chr16_+_631902 1.573 FAM195A
family with sequence similarity 195, member A
chr19_+_60851207 1.558 CCDC106
coiled-coil domain containing 106
chr20_+_36867708 1.555 NM_001172735
NM_015568
PPP1R16B

protein phosphatase 1, regulatory (inhibitor) subunit 16B

chr4_-_42353640 1.551 NM_001105529
NM_006095
ATP8A1

ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1

chr17_+_40655060 1.549 NM_005892
FMNL1
formin-like 1
chr17_-_44058612 1.547 NM_024017
HOXB9
homeobox B9
chr19_+_14405216 1.543 PKN1
protein kinase N1
chr22_-_20314366 1.533 YDJC
YdjC homolog (bacterial)
chr2_+_113648020 1.491 NM_012455
PSD4
pleckstrin and Sec7 domain containing 4
chr1_-_111548440 1.483 DENND2D
DENN/MADD domain containing 2D
chr16_-_1369613 1.474 NM_001193389
NM_023076
UNKL

unkempt homolog (Drosophila)-like

chr10_-_23043042 1.464 PIP4K2A
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
chr10_-_98470164 1.458 NM_152309
PIK3AP1
phosphoinositide-3-kinase adaptor protein 1
chr19_+_6723801 1.449


chr6_+_31647854 1.438 NM_001159740
LTA
lymphotoxin alpha (TNF superfamily, member 1)
chr6_+_36206239 1.437 NM_002754
MAPK13
mitogen-activated protein kinase 13
chr2_+_219453487 1.416 NM_025216
WNT10A
wingless-type MMTV integration site family, member 10A
chr2_+_113648036 1.408 PSD4
pleckstrin and Sec7 domain containing 4
chr1_-_1701313 1.406 NM_001198994
NADK
NAD kinase
chr9_+_139292094 1.388 NM_017723
C9orf167
chromosome 9 open reading frame 167
chr12_+_131797455 1.383 NM_001170543
NM_001170544
NM_138575
PGAM5


phosphoglycerate mutase family member 5


chr7_+_149696792 1.382 NM_001099695
NM_001099696
NM_013400
REPIN1


replication initiator 1


chr17_-_60345364 1.373 NM_199340
LRRC37A3
leucine rich repeat containing 37, member A3
chr7_+_74877568 1.355 NSUN5P1
NOP2/Sun domain family, member 5 pseudogene 1
chr1_-_24112345 1.336 NM_001841
CNR2
cannabinoid receptor 2 (macrophage)
chr17_-_71747867 1.317 NM_052916
RNF157
ring finger protein 157
chr14_+_30413393 1.305 NM_001135058
NM_004086
COCH

coagulation factor C homolog, cochlin (Limulus polyphemus)

chr22_-_22511173 1.299 NM_001002862
NM_001135751
NM_198440
DERL3


Der1-like domain family, member 3


chr3_-_13436725 1.289 NUP210
nucleoporin 210kDa
chr19_+_18145631 1.284 IFI30
interferon, gamma-inducible protein 30
chr19_+_10392128 1.265 NM_001111307
PDE4A
phosphodiesterase 4A, cAMP-specific
chr15_-_46257611 1.260 MYEF2
myelin expression factor 2
chr11_-_33847507 1.248 LMO2
LIM domain only 2 (rhombotin-like 1)
chr15_-_46257745 1.240 NM_016132
MYEF2
myelin expression factor 2
chr9_-_126945536 1.234 NM_001144877
NM_173690
SCAI

suppressor of cancer cell invasion

chrX_-_118711088 1.233 SEPT6
septin 6
chr16_+_631828 1.222 NM_138418
FAM195A
family with sequence similarity 195, member A
chr6_+_44295219 1.214 NM_001078174
NM_004955
SLC29A1

solute carrier family 29 (nucleoside transporters), member 1

chr10_-_103337872 1.213 POLL
polymerase (DNA directed), lambda
chr2_-_25328452 1.202 NM_153759
DNMT3A
DNA (cytosine-5-)-methyltransferase 3 alpha
chrX_-_118711144 1.194 SEPT6
septin 6
chr19_+_18145619 1.188 IFI30
interferon, gamma-inducible protein 30
chr22_-_36212160 1.173 NM_001166343
NM_002405
MFNG

MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase

chr10_+_31648103 1.163 NM_001174093
NM_001174095
NM_001174096
NM_030751
ZEB1



zinc finger E-box binding homeobox 1



chr5_-_138753443 1.162 NM_016459
MZB1
marginal zone B and B1 cell-specific protein
chr1_-_92724181 1.157 NM_001127216
GFI1
growth factor independent 1 transcription repressor
chrX_-_118711183 1.153 SEPT6
septin 6
chr6_+_31648071 1.150 NM_000595
LTA
lymphotoxin alpha (TNF superfamily, member 1)
chr11_-_684842 1.147 DEAF1
deformed epidermal autoregulatory factor 1 (Drosophila)
chr1_+_109827975 1.136 NM_153340
ATXN7L2
ataxin 7-like 2
chr3_+_16901455 1.132 NM_001144382
PLCL2
phospholipase C-like 2
chr20_+_60744268 1.130 SLCO4A1
solute carrier organic anion transporter family, member 4A1
chr10_-_31647925 1.129 LOC220930
hypothetical LOC220930
chr5_+_126140949 1.121 LMNB1
lamin B1
chr14_-_22358752 1.118 NM_001126106
SLC7A7
solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr7_-_8268292 1.118 NM_001136020
ICA1
islet cell autoantigen 1, 69kDa
chr19_-_6621078 1.116 TNFSF14
tumor necrosis factor (ligand) superfamily, member 14
chr10_+_31647425 1.115 ZEB1
zinc finger E-box binding homeobox 1
chr17_+_18971506 1.109 NM_001129778
GRAPL
GRB2-related adaptor protein-like
chr19_+_47073029 1.104 NM_001783
NM_021601
CD79A

CD79a molecule, immunoglobulin-associated alpha

chr8_-_59734975 1.095 NSMAF
neutral sphingomyelinase (N-SMase) activation associated factor
chr10_+_102811542 1.094 KAZALD1
Kazal-type serine peptidase inhibitor domain 1
chr20_+_60744231 1.094 NM_016354
SLCO4A1
solute carrier organic anion transporter family, member 4A1
chr6_-_44333002 1.090 NM_178148
SLC35B2
solute carrier family 35, member B2
chr17_-_36594652 1.086 NM_033060
KRTAP4-1
keratin associated protein 4-1
chr20_-_57015698 1.085 NM_001336
CTSZ
cathepsin Z
chr8_-_59734801 1.081 NSMAF
neutral sphingomyelinase (N-SMase) activation associated factor
chr16_+_51690564 1.072 CHD9
chromodomain helicase DNA binding protein 9
chr9_-_125070613 1.068 NM_018387
STRBP
spermatid perinuclear RNA binding protein
chr1_+_165865953 1.059 NM_052862
RCSD1
RCSD domain containing 1
chr15_+_89228668 1.055 NM_001143785
NM_002005
FES

feline sarcoma oncogene

chr8_-_59734939 1.048 NSMAF
neutral sphingomyelinase (N-SMase) activation associated factor
chr5_+_126140746 1.045 LMNB1
lamin B1
chr6_-_25019173 1.044 NM_014722
FAM65B
family with sequence similarity 65, member B
chr20_-_23014828 1.040 NM_012072
CD93
CD93 molecule
chr7_+_120378052 1.038 NM_019071
NM_198267
ING3

inhibitor of growth family, member 3

chr22_-_49311722 1.030 NM_001169109
SCO2
SCO cytochrome oxidase deficient homolog 2 (yeast)
chr17_-_70778667 1.024 MIF4GD
MIF4G domain containing
chr2_-_24436795 1.018 NM_006277
NM_019595
NM_147152
ITSN2


intersectin 2


chr11_-_124137260 1.007 NM_138961
ESAM
endothelial cell adhesion molecule
chrX_-_118711350 1.007 NM_015129
NM_145799
NM_145800
NM_145802
SEPT6



septin 6



chr12_-_25041639 1.004 NM_001101339
C12orf77
chromosome 12 open reading frame 77
chr19_-_14177980 0.999 NM_001008701
NM_014921
LPHN1

latrophilin 1

chr8_+_143805595 0.995 NM_016647
C8orf55
chromosome 8 open reading frame 55
chr16_-_87405817 0.991 NM_000485
NM_001030018
APRT

adenine phosphoribosyltransferase

chr2_+_112529270 0.991 NM_032824
TMEM87B
transmembrane protein 87B
chr2_-_105312536 0.990 NM_001142621
NM_004257
TGFBRAP1

transforming growth factor, beta receptor associated protein 1

chr2_+_170298487 0.987


chr8_-_59734957 0.986 NM_003580
NSMAF
neutral sphingomyelinase (N-SMase) activation associated factor
chr1_-_27113018 0.980 NM_021969
NR0B2
nuclear receptor subfamily 0, group B, member 2
chr19_-_44060729 0.978 NM_001195833
NM_198445
RINL

Ras and Rab interactor-like

chrX_+_152562013 0.975 DUSP9
dual specificity phosphatase 9
chr22_-_49317873 0.974 NM_001014440
ODF3B
outer dense fiber of sperm tails 3B
chr11_+_70926718 0.968 NM_021046
KRTAP5-8
keratin associated protein 5-8
chr1_+_12046020 0.968 NM_001243
TNFRSF8
tumor necrosis factor receptor superfamily, member 8
chr1_+_1062137 0.966 LOC254099
hypothetical protein LOC254099
chr16_+_23754997 0.965 PRKCB
protein kinase C, beta
chr7_+_50314801 0.961 NM_006060
IKZF1
IKAROS family zinc finger 1 (Ikaros)
chr14_-_105392671 0.954


chr17_-_3814334 0.951 NM_005173
NM_174953
NM_174954
NM_174955
NM_174956
NM_174957
NM_174958
ATP2A3






ATPase, Ca++ transporting, ubiquitous






chr2_-_208198217 0.948 NM_001127395
METTL21A
methyltransferase like 21A
chr12_-_61615124 0.946 PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr2_+_112529371 0.944 TMEM87B
transmembrane protein 87B
chr11_+_67567022 0.941 NM_006053
TCIRG1
T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
chr8_-_59734742 0.938 NSMAF
neutral sphingomyelinase (N-SMase) activation associated factor
chr21_+_44377913 0.934 NM_004649
NM_198155
C21orf33

chromosome 21 open reading frame 33

chr20_+_42463279 0.932 NM_000457
NM_178849
NM_178850
HNF4A


hepatocyte nuclear factor 4, alpha


chr21_+_44377974 0.928 C21orf33
chromosome 21 open reading frame 33
chr1_-_109651140 0.928 NM_001010985
MYBPHL
myosin binding protein H-like
chr6_-_41781655 0.924 TFEB
transcription factor EB
chr1_+_229181462 0.920 ARV1
ARV1 homolog (S. cerevisiae)
chr9_-_125070675 0.920 NM_001171137
STRBP
spermatid perinuclear RNA binding protein
chr15_+_81567327 0.912 NM_001144903
NM_023003
TM6SF1

transmembrane 6 superfamily member 1

chr9_-_35640852 0.910 NM_014450
SIT1
signaling threshold regulating transmembrane adaptor 1
chr2_+_190753833 0.909 NM_001042519
NM_032321
C2orf88

chromosome 2 open reading frame 88

chr8_-_59734474 0.905 NM_001144772
NSMAF
neutral sphingomyelinase (N-SMase) activation associated factor
chr17_-_16197433 0.903 NM_181716
CENPV
centromere protein V
chr3_+_45611180 0.902 NM_014240
LIMD1
LIM domains containing 1
chr1_+_229181417 0.900 NM_022786
ARV1
ARV1 homolog (S. cerevisiae)
chr17_-_4831644 0.898 NM_001171166
NM_015099
CAMTA2

calmodulin binding transcription activator 2

chr15_+_48261649 0.898 NM_001159629
NM_003645
SLC27A2

solute carrier family 27 (fatty acid transporter), member 2

chr5_+_139008667 0.897 CXXC5
CXXC finger protein 5
chr19_+_6723705 0.896 NM_005428
VAV1
vav 1 guanine nucleotide exchange factor
chr1_+_39229474 0.892 NM_001136275
NM_024595
AKIRIN1

akirin 1

chr17_-_70778856 0.892 NM_020679
MIF4GD
MIF4G domain containing
chr20_-_62081434 0.888 NM_080621
SAMD10
sterile alpha motif domain containing 10
chr2_-_242205556 0.885 NM_001164356
THAP4
THAP domain containing 4
chr7_+_73262264 0.880 LAT2
linker for activation of T cells family, member 2
chr12_-_8271460 0.876 NM_018088
FAM90A1
family with sequence similarity 90, member A1
chr3_-_129690056 0.866 NM_001145661
GATA2
GATA binding protein 2
chr19_+_18312365 0.864 NM_017712
FKBP8
PGPEP1
FK506 binding protein 8, 38kDa
pyroglutamyl-peptidase I
chr11_+_65164167 0.864 NM_153253
SIPA1
signal-induced proliferation-associated 1
chr9_-_96441409 0.863 FBP1
fructose-1,6-bisphosphatase 1
chr19_-_7607852 0.863


chr9_-_91302707 0.862 SEMA4D
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
chr7_+_73262283 0.852 LAT2
linker for activation of T cells family, member 2
chr16_+_711139 0.849 NM_023933
FAM173A
family with sequence similarity 173, member A
chr21_+_41719847 0.848 NM_002462
NM_001178046
MX1

myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)

chr9_+_70509925 0.847 NM_003558
PIP5K1B
phosphatidylinositol-4-phosphate 5-kinase, type I, beta
chr6_+_16237300 0.847 MYLIP
myosin regulatory light chain interacting protein
chr4_+_154606900 0.846 NM_001131007
NM_015196
KIAA0922

KIAA0922

chr5_+_75734759 0.845 NM_006633
IQGAP2
IQ motif containing GTPase activating protein 2
chr10_-_115603848 0.845 NM_014881
DCLRE1A
DNA cross-link repair 1A
chr9_-_96441567 0.838 FBP1
fructose-1,6-bisphosphatase 1
chr8_-_145609737 0.831 SLC39A4
solute carrier family 39 (zinc transporter), member 4
chr9_+_263025 0.826 NM_001190458
NM_001193536
DOCK8

dedicator of cytokinesis 8

chr7_+_73262188 0.823 LAT2
linker for activation of T cells family, member 2
chr3_+_197851034 0.822 LRRC33
leucine rich repeat containing 33
chr20_+_42463419 0.821 HNF4A
hepatocyte nuclear factor 4, alpha
chr2_-_25390266 0.821 DNMT3A
DNA (cytosine-5-)-methyltransferase 3 alpha
chr2_-_208197940 0.819 NM_145280
METTL21A
methyltransferase like 21A
chr17_-_60346042 0.819 LRRC37A3
leucine rich repeat containing 37, member A3
chrX_-_152938441 0.819 IRAK1
interleukin-1 receptor-associated kinase 1
chr6_-_3172775 0.814 NM_178012
TUBB2B
tubulin, beta 2B
chr12_-_7793335 0.814 NM_130441
NM_203503
CLEC4C

C-type lectin domain family 4, member C


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.26 2.82e-03 GO:0023051 regulation of signaling
1.48 1.43e-02 GO:0046903 secretion

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.07 4.80e-05 GO:0044424 intracellular part
1.06 2.24e-04 GO:0005622 intracellular
1.09 5.23e-04 GO:0005737 cytoplasm
1.06 2.27e-02 GO:0043226 organelle
1.06 2.63e-02 GO:0043229 intracellular organelle

Gene overrepresentation in function category:

enrichment   p-value GO term description
3.68 3.98e-02 GO:0030159 receptor signaling complex scaffold activity