Motif ID: MAFB.p2

Z-value: 2.605


Transcription factors associated with MAFB.p2:

Gene SymbolEntrez IDGene Name
MAFB 9935 v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MAFBchr20_-_387512890.582.0e-02Click!


Activity profile for motif MAFB.p2.

activity profile for motif MAFB.p2


Sorted Z-values histogram for motif MAFB.p2

Sorted Z-values for motif MAFB.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MAFB.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_-_37999519 3.508


chr4_-_140696740 3.501 NM_030648
SETD7
SET domain containing (lysine methyltransferase) 7
chr6_+_45498354 3.451 RUNX2
runt-related transcription factor 2
chr6_+_45498262 3.304 RUNX2
runt-related transcription factor 2
chr15_-_37999717 2.973 GPR176
G protein-coupled receptor 176
chr9_-_109291575 2.862 KLF4
Kruppel-like factor 4 (gut)
chr5_+_60663842 2.851 NM_020928
ZSWIM6
zinc finger, SWIM-type containing 6
chr8_+_37672427 2.794 NM_025069
ZNF703
zinc finger protein 703
chr12_+_52665196 2.758 NM_017409
HOXC10
homeobox C10
chr4_-_141293572 2.718 MAML3
mastermind-like 3 (Drosophila)
chr2_-_227371698 2.506 NM_005544
IRS1
insulin receptor substrate 1
chr13_-_25523164 2.289 NM_001007538
SHISA2
shisa homolog 2 (Xenopus laevis)
chr4_-_111763356 2.285 PITX2
paired-like homeodomain 2
chr4_-_111763655 2.253 NM_000325
PITX2
paired-like homeodomain 2
chr16_+_81218142 2.161 CDH13
cadherin 13, H-cadherin (heart)
chr11_-_66945190 2.160 PPP1CA
protein phosphatase 1, catalytic subunit, alpha isozyme
chr16_+_81218074 2.132 NM_001257
CDH13
cadherin 13, H-cadherin (heart)
chr4_-_141294682 2.132 NM_018717
MAML3
mastermind-like 3 (Drosophila)
chr2_-_161058120 2.108 RBMS1
RNA binding motif, single stranded interacting protein 1
chr15_-_32875040 2.000 NM_005159
ACTC1
actin, alpha, cardiac muscle 1
chr17_-_36475652 1.989 NM_033184
KRTAP2-4
keratin associated protein 2-4
chr7_-_27190882 1.983 HOXA11
homeobox A11
chr7_-_127458231 1.977 NM_022143
LRRC4
leucine rich repeat containing 4
chr1_+_64012154 1.952 NM_001083592
NM_005012
ROR1

receptor tyrosine kinase-like orphan receptor 1

chr11_-_10272256 1.940 NM_030962
SBF2
SET binding factor 2
chr13_-_76358370 1.925 KCTD12
potassium channel tetramerisation domain containing 12
chr12_-_26166485 1.882 BHLHE41
basic helix-loop-helix family, member e41
chr12_+_26239755 1.880 NM_005086
SSPN
sarcospan (Kras oncogene-associated gene)
chr18_-_21185968 1.863 ZNF521
zinc finger protein 521
chr15_-_80125514 1.838 MEX3B
mex-3 homolog B (C. elegans)
chr18_-_24010944 1.835 CDH2
cadherin 2, type 1, N-cadherin (neuronal)
chr2_-_183611470 1.822 NM_013436
NM_205842
NCKAP1

NCK-associated protein 1

chr15_-_46724360 1.820 FBN1
fibrillin 1
chr7_+_27190688 1.804


chr2_-_236741352 1.776 NM_001485
GBX2
gastrulation brain homeobox 2
chr8_+_106400322 1.749 NM_012082
ZFPM2
zinc finger protein, multitype 2
chr8_+_32525269 1.720 NM_001160002
NM_001160004
NM_001160005
NM_001160007
NM_001160008
NM_004495
NM_013956
NM_013957
NM_013958
NM_013960
NM_013964
NRG1










neuregulin 1










chr3_+_173240136 1.690 FNDC3B
fibronectin type III domain containing 3B
chr15_+_41597097 1.663 NM_002373
MAP1A
microtubule-associated protein 1A
chr5_+_42459568 1.635 NM_000163
GHR
growth hormone receptor
chr20_+_19903778 1.632 RIN2
Ras and Rab interactor 2
chr20_-_22978141 1.629 NM_000361
THBD
thrombomodulin
chr6_-_132314004 1.607 NM_001901
CTGF
connective tissue growth factor
chr3_-_64186151 1.588 NM_198859
PRICKLE2
prickle homolog 2 (Drosophila)
chr1_-_203447314 1.567 NM_015375
NM_199462
DSTYK

dual serine/threonine and tyrosine protein kinase

chr5_+_179853977 1.565 NM_015455
CNOT6
CCR4-NOT transcription complex, subunit 6
chr18_-_21186107 1.564 NM_015461
ZNF521
zinc finger protein 521
chr5_-_72779585 1.546 FOXD1
forkhead box D1
chr4_+_14613395 1.546 NM_001177381
NM_001177382
NM_001177383
NM_001177384
NM_182485
NM_182646
CPEB2





cytoplasmic polyadenylation element binding protein 2





chr1_-_158091296 1.544 C1orf204
chromosome 1 open reading frame 204
chr5_+_66160359 1.543 NM_015183
MAST4
microtubule associated serine/threonine kinase family member 4
chr2_-_68400516 1.538 NM_001111101
NM_015463
CNRIP1

cannabinoid receptor interacting protein 1

chr17_+_1905104 1.537 NM_006497
HIC1
hypermethylated in cancer 1
chr15_+_72006015 1.536 LOXL1
lysyl oxidase-like 1
chr9_-_25668230 1.529 TUSC1
tumor suppressor candidate 1
chr9_-_16717887 1.522 BNC2
basonuclin 2
chr2_-_161058550 1.520 NM_002897
NM_016836
RBMS1

RNA binding motif, single stranded interacting protein 1

chr9_-_34448477 1.516 NM_001184940
NM_001184941
NM_001184942
NM_001184943
NM_001184944
NM_001184945
NM_147202
C9orf25






chromosome 9 open reading frame 25






chr2_-_160972606 1.511 RBMS1
RNA binding motif, single stranded interacting protein 1
chr21_-_43671355 1.509 NM_173354
SIK1
salt-inducible kinase 1
chr2_-_183610992 1.507 NCKAP1
NCK-associated protein 1
chr10_+_111755715 1.493 NM_019903
ADD3
adducin 3 (gamma)
chr6_+_71434192 1.461 NM_001044305
NM_021940
SMAP1

small ArfGAP 1

chr12_+_62524778 1.431 NM_020762
SRGAP1
SLIT-ROBO Rho GTPase activating protein 1
chr9_-_109291866 1.427 NM_004235
KLF4
Kruppel-like factor 4 (gut)
chr12_+_52618815 1.401 NM_017410
HOXC13
homeobox C13
chr15_-_81037554 1.401 NM_001079533
NM_001079534
NM_001079535
CPEB1


cytoplasmic polyadenylation element binding protein 1


chr10_+_72102563 1.389 NM_080722
NM_139155
ADAMTS14

ADAM metallopeptidase with thrombospondin type 1 motif, 14

chr10_+_71833905 1.384 EIF4EBP2
eukaryotic translation initiation factor 4E binding protein 2
chr9_-_128924819 1.384 NM_012098
ANGPTL2
angiopoietin-like 2
chr3_+_148610516 1.377 ZIC1
Zic family member 1 (odd-paired homolog, Drosophila)
chr2_+_30223253 1.370 NM_001127399
NM_001127400
NM_001127401
NM_016061
YPEL5



yippee-like 5 (Drosophila)



chr5_-_58370693 1.365 NM_001197221
NM_001197222
PDE4D

phosphodiesterase 4D, cAMP-specific

chr5_+_129268352 1.358 NM_175856
CHSY3
chondroitin sulfate synthase 3
chr9_-_128924782 1.353 ANGPTL2
angiopoietin-like 2
chr12_-_106011715 1.346 NM_004075
CRY1
cryptochrome 1 (photolyase-like)
chr10_+_71833920 1.345 EIF4EBP2
eukaryotic translation initiation factor 4E binding protein 2
chr13_+_100902942 1.330 NM_004791
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr11_+_19691397 1.330 NM_145117
NM_182964
NAV2

neuron navigator 2

chr2_-_192767494 1.321 TMEFF2
transmembrane protein with EGF-like and two follistatin-like domains 2
chr8_+_1936549 1.313 KBTBD11
kelch repeat and BTB (POZ) domain containing 11
chr2_+_238200922 1.313 NM_001137550
LRRFIP1
leucine rich repeat (in FLII) interacting protein 1
chr3_-_16530132 1.311 NM_015150
RFTN1
raftlin, lipid raft linker 1
chr15_-_50608296 1.300 NM_000259
NM_001142495
MYO5A

myosin VA (heavy chain 12, myoxin)

chr10_+_71833866 1.296 NM_004096
EIF4EBP2
eukaryotic translation initiation factor 4E binding protein 2
chr9_-_128924706 1.294 ANGPTL2
angiopoietin-like 2
chr10_+_96152175 1.288 NM_015188
TBC1D12
TBC1 domain family, member 12
chr10_+_74121844 1.285 NM_138357
CCDC109A
coiled-coil domain containing 109A
chr12_-_74711474 1.280 PHLDA1
pleckstrin homology-like domain, family A, member 1
chr19_-_1518875 1.273 NM_001174118
NM_203304
MEX3D

mex-3 homolog D (C. elegans)

chr15_+_97009194 1.273 IGF1R
insulin-like growth factor 1 receptor
chr1_-_72521079 1.270


chr3_+_112273352 1.262 PVRL3
poliovirus receptor-related 3
chr8_-_48813256 1.250 NM_005195
CEBPD
CCAAT/enhancer binding protein (C/EBP), delta
chr19_-_45888259 1.247 NM_004756
NUMBL
numb homolog (Drosophila)-like
chr12_+_26239535 1.244 NM_001135823
SSPN
sarcospan (Kras oncogene-associated gene)
chr11_+_94141151 1.244 NM_130847
AMOTL1
angiomotin like 1
chrX_-_34585287 1.242 NM_031442
TMEM47
transmembrane protein 47
chr17_+_52026058 1.240 NM_005450
NOG
noggin
chr16_+_85158357 1.236 NM_005251
FOXC2
forkhead box C2 (MFH-1, mesenchyme forkhead 1)
chr4_+_108965167 1.234 NM_001136258
SGMS2
sphingomyelin synthase 2
chr3_-_87122936 1.233 NM_016206
VGLL3
vestigial like 3 (Drosophila)
chr3_-_87122958 1.224 VGLL3
vestigial like 3 (Drosophila)
chr19_-_50977592 1.218 NM_001081560
NM_001081562
NM_004409
DMPK


dystrophia myotonica-protein kinase


chr9_-_79835970 1.204 NM_002072
GNAQ
guanine nucleotide binding protein (G protein), q polypeptide
chr19_-_50977586 1.195 DMPK
dystrophia myotonica-protein kinase
chr12_-_93568336 1.190 NM_020698
TMCC3
transmembrane and coiled-coil domain family 3
chr16_-_219339 1.183 NM_018032
NM_201412
LUC7L

LUC7-like (S. cerevisiae)

chr1_-_40140126 1.159 NM_001033081
NM_001033082
NM_005376
MYCL1


v-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived (avian)


chr1_-_85816520 1.152 NM_001134445
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr4_-_1655515 1.147 NM_001013622
NM_001174070
FAM53A

family with sequence similarity 53, member A

chr1_+_108544507 1.136


chr2_+_30223304 1.131 YPEL5
yippee-like 5 (Drosophila)
chr15_-_53667800 1.128 PYGO1
pygopus homolog 1 (Drosophila)
chr2_+_12774264 1.127 NM_021643
TRIB2
tribbles homolog 2 (Drosophila)
chr1_-_203447280 1.116 DSTYK
dual serine/threonine and tyrosine protein kinase
chr2_-_210744158 1.102 NM_152519
C2orf67
chromosome 2 open reading frame 67
chr7_+_115926679 1.102 NM_001233
NM_198212
CAV2

caveolin 2

chr2_+_109112428 1.102 NM_001099289
SH3RF3
SH3 domain containing ring finger 3
chr11_-_88864061 1.100 NM_001143836
NM_016931
NOX4

NADPH oxidase 4

chr1_-_31618405 1.098 NM_004102
FABP3
fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor)
chr16_-_71650034 1.096 NM_001164766
ZFHX3
zinc finger homeobox 3
chr1_-_206484258 1.093 NM_025179
PLXNA2
plexin A2
chr17_-_36456949 1.084 NM_001123387
KRTAP2-1
keratin associated protein 2-1
chr6_-_75972286 1.076 NM_004370
NM_080645
COL12A1

collagen, type XII, alpha 1

chr8_-_125453815 1.075 TMEM65
transmembrane protein 65
chr10_+_96152262 1.075 TBC1D12
TBC1 domain family, member 12
chr2_+_30223372 1.074 YPEL5
yippee-like 5 (Drosophila)
chr2_+_56265260 1.065


chr14_+_85066265 1.064 FLRT2
fibronectin leucine rich transmembrane protein 2
chr7_+_90731671 1.063 NM_003505
FZD1
frizzled homolog 1 (Drosophila)
chr1_-_143643324 1.060 NM_001002811
PDE4DIP
phosphodiesterase 4D interacting protein
chr11_-_72698050 1.059 LOC100287837
hypothetical protein LOC100287837
chr10_+_42953886 1.047 NM_018590
CSGALNACT2
chondroitin sulfate N-acetylgalactosaminyltransferase 2
chrX_+_66683075 1.047 AR
androgen receptor
chr7_+_33911636 1.039 NM_133468
BMPER
BMP binding endothelial regulator
chr2_-_45090025 1.035 NM_016932
SIX2
SIX homeobox 2
chr10_+_31648103 1.027 NM_001174093
NM_001174095
NM_001174096
NM_030751
ZEB1



zinc finger E-box binding homeobox 1



chr3_+_189354167 1.020 NM_001167672
LPP
LIM domain containing preferred translocation partner in lipoma
chr7_-_112513379 1.018 NM_001146266
NM_001146267
GPR85

G protein-coupled receptor 85

chr6_-_91063301 1.017 NM_001170794
BACH2
BTB and CNC homology 1, basic leucine zipper transcription factor 2
chr3_+_49002285 1.015 NM_177938
NM_177939
P4HTM

prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)

chr1_-_33202872 1.012 NM_001127361
NM_153341
RNF19B

ring finger protein 19B

chr1_+_182622987 1.010 C1orf21
chromosome 1 open reading frame 21
chr3_+_106568243 1.010 ALCAM
activated leukocyte cell adhesion molecule
chr3_-_185025989 1.008 NM_024871
MAP6D1
MAP6 domain containing 1
chr7_-_126819953 0.999 NM_176814
ZNF800
zinc finger protein 800
chr4_+_89732620 0.999 NM_014606
HERC3
hect domain and RLD 3
chr9_+_101623957 0.994 NM_006981
NM_173199
NR4A3

nuclear receptor subfamily 4, group A, member 3

chr1_-_108544486 0.990 NM_013386
SLC25A24
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
chr12_+_88626770 0.987 LOC338758
hypothetical LOC338758
chr10_+_59942874 0.983 NM_001080512
BICC1
bicaudal C homolog 1 (Drosophila)
chr14_+_85066207 0.982 NM_013231
FLRT2
fibronectin leucine rich transmembrane protein 2
chr6_+_21701942 0.981 NM_003107
SOX4
SRY (sex determining region Y)-box 4
chr16_-_30992574 0.978 ZNF668
zinc finger protein 668
chrX_+_51503219 0.978 NM_018094
GSPT2
G1 to S phase transition 2
chr15_+_36332258 0.977 NM_152594
SPRED1
sprouty-related, EVH1 domain containing 1
chr12_-_106011437 0.975 CRY1
cryptochrome 1 (photolyase-like)
chr9_+_35528890 0.973 RUSC2
RUN and SH3 domain containing 2
chr13_-_29322795 0.963 NM_007106
UBL3
ubiquitin-like 3
chr3_-_189354510 0.955 LOC339929
hypothetical LOC339929
chr15_-_23659329 0.955 NM_024490
ATP10A
ATPase, class V, type 10A
chr12_-_68369322 0.954 NM_152439
BEST3
bestrophin 3
chr7_-_19123787 0.953 NM_000474
TWIST1
twist homolog 1 (Drosophila)
chr7_-_19123765 0.951 TWIST1
twist homolog 1 (Drosophila)
chr2_-_156897286 0.950 NM_006186
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr9_-_72218098 0.948 KLF9
Kruppel-like factor 9
chr10_-_75080784 0.942 NM_024875
SYNPO2L
synaptopodin 2-like
chr17_+_36515166 0.937 NM_001146041
KRTAP4-9
keratin associated protein 4-9
chr17_+_1580504 0.936 WDR81
WD repeat domain 81
chr10_+_6284845 0.935 NM_004566
PFKFB3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr15_-_31147376 0.934 NM_001103184
FMN1
formin 1
chr12_+_32150922 0.933 BICD1
bicaudal D homolog 1 (Drosophila)
chr6_-_85530617 0.930 NM_001080508
TBX18
T-box 18
chr11_+_110916629 0.926 LAYN
layilin
chr1_+_110328922 0.926 AHCYL1
adenosylhomocysteinase-like 1
chr10_-_106088151 0.924 ITPRIP
inositol 1,4,5-triphosphate receptor interacting protein
chr12_-_29827952 0.923 NM_001193451
TMTC1
transmembrane and tetratricopeptide repeat containing 1
chr10_-_118021532 0.919 NM_145793
GFRA1
GDNF family receptor alpha 1
chr5_+_40715778 0.917 NM_000958
PTGER4
prostaglandin E receptor 4 (subtype EP4)
chr2_+_191453813 0.915 GLS
glutaminase
chr5_+_40715799 0.913 PTGER4
prostaglandin E receptor 4 (subtype EP4)
chr2_+_159021653 0.913 PKP4
plakophilin 4
chr3_-_188945921 0.910 BCL6
B-cell CLL/lymphoma 6
chr1_+_66772393 0.906 NM_032291
SGIP1
SH3-domain GRB2-like (endophilin) interacting protein 1
chr1_-_143643064 0.902 PDE4DIP
phosphodiesterase 4D interacting protein
chr14_-_102593384 0.893 NM_006035
CDC42BPB
CDC42 binding protein kinase beta (DMPK-like)
chr10_+_131824664 0.892 GLRX3
glutaredoxin 3
chr5_-_172976196 0.890 BOD1
biorientation of chromosomes in cell division 1
chr1_-_72520735 0.889 NM_173808
NEGR1
neuronal growth regulator 1
chr14_-_26136799 0.889 NM_002515
NM_006489
NM_006491
NOVA1


neuro-oncological ventral antigen 1


chr5_-_146813343 0.888 NM_001387
DPYSL3
dihydropyrimidinase-like 3
chr11_-_85108030 0.886 NM_001162952
NM_206930
SYTL2

synaptotagmin-like 2

chr8_-_11096257 0.885 NM_173683
XKR6
XK, Kell blood group complex subunit-related family, member 6
chr22_-_20235372 0.883 NM_001128635
RIMBP3B
RIMS binding protein 3B
chr11_-_1725924 0.883 NM_001170820
LOC402778
CD225 family protein FLJ76511
chrX_+_149282097 0.881 NM_001177465
MAMLD1
mastermind-like domain containing 1
chr22_-_34754343 0.880 NM_001082578
NM_001082579
RBFOX2

RNA binding protein, fox-1 homolog (C. elegans) 2

chr17_-_7458849 0.879 NM_004860
FXR2
fragile X mental retardation, autosomal homolog 2
chr2_+_23461802 0.876 NM_052920
KLHL29
kelch-like 29 (Drosophila)

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.27 3.09e-16 GO:0032502 developmental process
1.17 4.60e-16 GO:0050794 regulation of cellular process
1.28 2.22e-15 GO:0007275 multicellular organismal development
1.16 7.77e-15 GO:0050789 regulation of biological process
1.30 3.98e-14 GO:0048731 system development
1.15 6.62e-14 GO:0065007 biological regulation
1.28 6.79e-14 GO:0048856 anatomical structure development
1.42 9.01e-13 GO:0007399 nervous system development
1.34 2.34e-12 GO:0030154 cell differentiation
1.33 6.33e-12 GO:0048523 negative regulation of cellular process
1.33 1.07e-11 GO:0048869 cellular developmental process
1.62 3.50e-11 GO:0007167 enzyme linked receptor protein signaling pathway
1.30 5.16e-11 GO:0048519 negative regulation of biological process
1.18 9.95e-11 GO:0032501 multicellular organismal process
1.38 1.41e-10 GO:0009653 anatomical structure morphogenesis
1.22 1.49e-10 GO:0023052 signaling
1.50 2.48e-10 GO:0022008 neurogenesis
1.23 3.25e-10 GO:0031323 regulation of cellular metabolic process
1.23 4.95e-10 GO:0080090 regulation of primary metabolic process
1.66 6.57e-10 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.23 1.09e-09 GO:0060255 regulation of macromolecule metabolic process
1.28 1.76e-09 GO:0048522 positive regulation of cellular process
1.49 2.68e-09 GO:0048699 generation of neurons
1.26 3.70e-09 GO:0048518 positive regulation of biological process
1.08 4.19e-09 GO:0009987 cellular process
1.22 5.55e-09 GO:0007165 signal transduction
1.46 1.02e-08 GO:0048468 cell development
1.64 1.17e-08 GO:0000904 cell morphogenesis involved in differentiation
1.65 1.77e-08 GO:0072358 cardiovascular system development
1.65 1.77e-08 GO:0072359 circulatory system development
1.19 3.03e-08 GO:0019222 regulation of metabolic process
1.80 9.41e-08 GO:0001944 vasculature development
1.30 1.05e-07 GO:0007166 cell surface receptor linked signaling pathway
1.36 1.42e-07 GO:0051239 regulation of multicellular organismal process
1.65 2.36e-07 GO:0007409 axonogenesis
1.50 2.40e-07 GO:0030182 neuron differentiation
1.55 3.32e-07 GO:0048666 neuron development
1.41 3.68e-07 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.23 4.62e-07 GO:0009889 regulation of biosynthetic process
1.62 5.17e-07 GO:0048667 cell morphogenesis involved in neuron differentiation
1.24 5.49e-07 GO:0010556 regulation of macromolecule biosynthetic process
1.23 9.91e-07 GO:0031326 regulation of cellular biosynthetic process
1.61 1.06e-06 GO:0048812 neuron projection morphogenesis
1.41 1.12e-06 GO:0050793 regulation of developmental process
1.24 1.32e-06 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.22 1.88e-06 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.57 2.13e-06 GO:0031175 neuron projection development
1.22 2.54e-06 GO:0051171 regulation of nitrogen compound metabolic process
1.50 3.62e-06 GO:0000902 cell morphogenesis
1.49 4.34e-06 GO:0032989 cellular component morphogenesis
1.47 4.36e-06 GO:0010628 positive regulation of gene expression
1.33 5.41e-06 GO:0009893 positive regulation of metabolic process
1.17 6.63e-06 GO:0051716 cellular response to stimulus
1.48 8.02e-06 GO:0045893 positive regulation of transcription, DNA-dependent
1.44 8.21e-06 GO:0010557 positive regulation of macromolecule biosynthetic process
1.43 9.34e-06 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.34 1.06e-05 GO:0010604 positive regulation of macromolecule metabolic process
1.42 1.31e-05 GO:0051173 positive regulation of nitrogen compound metabolic process
1.45 1.38e-05 GO:0045595 regulation of cell differentiation
1.33 1.67e-05 GO:0031325 positive regulation of cellular metabolic process
1.46 2.62e-05 GO:0030030 cell projection organization
1.26 3.44e-05 GO:0006464 protein modification process
1.51 3.69e-05 GO:0048858 cell projection morphogenesis
1.71 3.95e-05 GO:0001568 blood vessel development
1.21 4.38e-05 GO:0010468 regulation of gene expression
1.23 4.43e-05 GO:0051252 regulation of RNA metabolic process
1.41 4.61e-05 GO:2000026 regulation of multicellular organismal development
1.44 4.69e-05 GO:0051254 positive regulation of RNA metabolic process
1.23 4.73e-05 GO:0006355 regulation of transcription, DNA-dependent
1.50 7.18e-05 GO:0032990 cell part morphogenesis
1.38 7.78e-05 GO:0031328 positive regulation of cellular biosynthetic process
1.38 9.57e-05 GO:0009891 positive regulation of biosynthetic process
1.81 1.08e-04 GO:0007517 muscle organ development
1.66 1.80e-04 GO:0061061 muscle structure development
1.60 1.80e-04 GO:0007411 axon guidance
1.96 1.85e-04 GO:0060537 muscle tissue development
1.33 2.22e-04 GO:0010646 regulation of cell communication
1.61 2.60e-04 GO:0001501 skeletal system development
1.62 2.79e-04 GO:0022603 regulation of anatomical structure morphogenesis
1.74 2.82e-04 GO:0048514 blood vessel morphogenesis
1.72 3.10e-04 GO:0048011 nerve growth factor receptor signaling pathway
1.36 3.50e-04 GO:0009888 tissue development
1.23 4.07e-04 GO:0048513 organ development
1.33 4.78e-04 GO:0007154 cell communication
1.23 5.00e-04 GO:0043412 macromolecule modification
1.25 5.43e-04 GO:0023051 regulation of signaling
1.48 8.21e-04 GO:0048646 anatomical structure formation involved in morphogenesis
1.30 1.17e-03 GO:0051246 regulation of protein metabolic process
1.45 1.41e-03 GO:0007417 central nervous system development
1.33 1.41e-03 GO:0010605 negative regulation of macromolecule metabolic process
1.13 1.61e-03 GO:0044260 cellular macromolecule metabolic process
1.33 1.67e-03 GO:0031324 negative regulation of cellular metabolic process
1.31 1.79e-03 GO:0032268 regulation of cellular protein metabolic process
1.48 2.10e-03 GO:0032583 regulation of gene-specific transcription
1.49 2.13e-03 GO:0016477 cell migration
1.92 2.16e-03 GO:0014706 striated muscle tissue development
1.39 2.25e-03 GO:0010558 negative regulation of macromolecule biosynthetic process
1.26 2.31e-03 GO:0009966 regulation of signal transduction
1.38 2.34e-03 GO:0009890 negative regulation of biosynthetic process
1.86 2.46e-03 GO:0008286 insulin receptor signaling pathway
1.57 2.61e-03 GO:0032870 cellular response to hormone stimulus
1.38 3.33e-03 GO:0042325 regulation of phosphorylation
1.31 3.58e-03 GO:0009892 negative regulation of metabolic process
1.33 3.73e-03 GO:0040011 locomotion
1.45 3.75e-03 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.37 4.16e-03 GO:0009790 embryo development
1.33 4.38e-03 GO:0051128 regulation of cellular component organization
1.36 4.69e-03 GO:0019220 regulation of phosphate metabolic process
1.36 4.69e-03 GO:0051174 regulation of phosphorus metabolic process
1.37 4.78e-03 GO:0031327 negative regulation of cellular biosynthetic process
1.31 7.88e-03 GO:0006351 transcription, DNA-dependent
1.40 8.01e-03 GO:0051253 negative regulation of RNA metabolic process
1.47 8.07e-03 GO:0009968 negative regulation of signal transduction
1.52 8.81e-03 GO:0071495 cellular response to endogenous stimulus
1.45 9.02e-03 GO:0010648 negative regulation of cell communication
1.25 9.31e-03 GO:0035556 intracellular signal transduction
1.44 9.41e-03 GO:0048870 cell motility
1.44 9.41e-03 GO:0051674 localization of cell
1.52 1.10e-02 GO:0060284 regulation of cell development
1.62 1.36e-02 GO:0071375 cellular response to peptide hormone stimulus
1.72 1.41e-02 GO:0001525 angiogenesis
1.33 1.50e-02 GO:0007267 cell-cell signaling
1.37 1.51e-02 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.40 1.53e-02 GO:0045892 negative regulation of transcription, DNA-dependent
1.37 1.57e-02 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.37 1.60e-02 GO:0042060 wound healing
1.28 1.60e-02 GO:0042981 regulation of apoptosis
1.28 1.62e-02 GO:0043067 regulation of programmed cell death
1.47 1.92e-02 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
1.36 2.00e-02 GO:0001932 regulation of protein phosphorylation
1.37 2.09e-02 GO:0009887 organ morphogenesis
1.43 2.24e-02 GO:0023057 negative regulation of signaling
1.31 2.27e-02 GO:0031399 regulation of protein modification process
1.38 2.29e-02 GO:0006928 cellular component movement
1.36 2.64e-02 GO:0010629 negative regulation of gene expression
1.43 3.02e-02 GO:0040008 regulation of growth
1.27 3.05e-02 GO:0010941 regulation of cell death
2.15 3.15e-02 GO:0007519 skeletal muscle tissue development
1.28 3.23e-02 GO:0042127 regulation of cell proliferation
1.09 3.32e-02 GO:0050896 response to stimulus
1.11 3.54e-02 GO:0043170 macromolecule metabolic process
1.35 3.57e-02 GO:0051172 negative regulation of nitrogen compound metabolic process
1.39 4.23e-02 GO:0030001 metal ion transport
1.27 4.32e-02 GO:0032879 regulation of localization
1.41 4.42e-02 GO:0051094 positive regulation of developmental process
1.47 4.62e-02 GO:0044057 regulation of system process
2.08 4.80e-02 GO:0060538 skeletal muscle organ development

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.19 5.81e-06 GO:0043234 protein complex
1.06 2.16e-05 GO:0044424 intracellular part
1.06 7.36e-05 GO:0005622 intracellular
1.47 7.94e-04 GO:0045202 synapse
1.73 3.30e-03 GO:0005912 adherens junction
1.67 6.05e-03 GO:0070161 anchoring junction
1.34 7.60e-03 GO:0030054 cell junction
1.09 9.36e-03 GO:0005634 nucleus
1.16 1.49e-02 GO:0044459 plasma membrane part
1.06 1.80e-02 GO:0043226 organelle
1.20 1.81e-02 GO:0005856 cytoskeleton
1.77 1.86e-02 GO:0044449 contractile fiber part
1.06 2.62e-02 GO:0043229 intracellular organelle
1.12 4.60e-02 GO:0032991 macromolecular complex

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.15 4.22e-15 GO:0005515 protein binding
1.46 1.31e-10 GO:0001071 nucleic acid binding transcription factor activity
1.46 1.31e-10 GO:0003700 sequence-specific DNA binding transcription factor activity
1.55 3.50e-10 GO:0043565 sequence-specific DNA binding
1.44 6.30e-10 GO:0030528 transcription regulator activity
1.07 6.40e-10 GO:0005488 binding
1.36 2.34e-04 GO:0019899 enzyme binding
1.57 3.49e-04 GO:0016564 transcription repressor activity
1.43 3.72e-03 GO:0019904 protein domain specific binding
1.53 8.23e-03 GO:0032403 protein complex binding
1.58 1.85e-02 GO:0000975 regulatory region DNA binding
1.58 1.85e-02 GO:0001067 regulatory region nucleic acid binding
1.58 1.85e-02 GO:0044212 transcription regulatory region DNA binding
1.41 2.69e-02 GO:0000988 protein binding transcription factor activity
1.41 2.69e-02 GO:0000989 transcription factor binding transcription factor activity
1.58 2.97e-02 GO:0010843 promoter binding
1.45 3.59e-02 GO:0016563 transcription activator activity
1.41 3.87e-02 GO:0003712 transcription cofactor activity