Motif ID: MAFB.p2

Z-value: 2.605


Transcription factors associated with MAFB.p2:

Gene SymbolEntrez IDGene Name
MAFB 9935 v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MAFBchr20_-_387512890.582.0e-02Click!


Activity profile for motif MAFB.p2.

activity profile for motif MAFB.p2


Sorted Z-values histogram for motif MAFB.p2

Sorted Z-values for motif MAFB.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MAFB.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr15_-_37999519 3.508


chr4_-_140696740 3.501 NM_030648
 SETD7
SET domain containing (lysine methyltransferase) 7
chr6_+_45498354 3.451 RUNX2
runt-related transcription factor 2
chr6_+_45498262 3.304 RUNX2
runt-related transcription factor 2
chr15_-_37999717 2.973 GPR176
G protein-coupled receptor 176
chr9_-_109291575 2.862 KLF4
Kruppel-like factor 4 (gut)
chr5_+_60663842 2.851 NM_020928
 ZSWIM6
zinc finger, SWIM-type containing 6
chr8_+_37672427 2.794 NM_025069
 ZNF703
zinc finger protein 703
chr12_+_52665196 2.758 NM_017409
 HOXC10
homeobox C10
chr4_-_141293572 2.718 MAML3
mastermind-like 3 (Drosophila)
chr2_-_227371698 2.506 NM_005544
 IRS1
insulin receptor substrate 1
chr13_-_25523164 2.289 NM_001007538
 SHISA2
shisa homolog 2 (Xenopus laevis)
chr4_-_111763356 2.285 PITX2
paired-like homeodomain 2
chr4_-_111763655 2.253 NM_000325
 PITX2
paired-like homeodomain 2
chr16_+_81218142 2.161 CDH13
cadherin 13, H-cadherin (heart)
chr11_-_66945190 2.160 PPP1CA
protein phosphatase 1, catalytic subunit, alpha isozyme
chr16_+_81218074 2.132 NM_001257
 CDH13
cadherin 13, H-cadherin (heart)
chr4_-_141294682 2.132 NM_018717
 MAML3
mastermind-like 3 (Drosophila)
chr2_-_161058120 2.108 RBMS1
RNA binding motif, single stranded interacting protein 1
chr15_-_32875040 2.000 NM_005159
 ACTC1
actin, alpha, cardiac muscle 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 147 entries
enrichment   p-value GO term description
2.15 3.15e-02 GO:0007519 skeletal muscle tissue development
2.08 4.80e-02 GO:0060538 skeletal muscle organ development
1.96 1.85e-04 GO:0060537 muscle tissue development
1.92 2.16e-03 GO:0014706 striated muscle tissue development
1.86 2.46e-03 GO:0008286 insulin receptor signaling pathway
1.81 1.08e-04 GO:0007517 muscle organ development
1.80 9.41e-08 GO:0001944 vasculature development
1.74 2.82e-04 GO:0048514 blood vessel morphogenesis
1.72 3.10e-04 GO:0048011 nerve growth factor receptor signaling pathway
1.72 1.41e-02 GO:0001525 angiogenesis
1.71 3.95e-05 GO:0001568 blood vessel development
1.66 6.57e-10 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.66 1.80e-04 GO:0061061 muscle structure development
1.65 1.77e-08 GO:0072358 cardiovascular system development
1.65 1.77e-08 GO:0072359 circulatory system development
1.65 2.36e-07 GO:0007409 axonogenesis
1.64 1.17e-08 GO:0000904 cell morphogenesis involved in differentiation
1.62 3.50e-11 GO:0007167 enzyme linked receptor protein signaling pathway
1.62 5.17e-07 GO:0048667 cell morphogenesis involved in neuron differentiation
1.62 2.79e-04 GO:0022603 regulation of anatomical structure morphogenesis

Gene overrepresentation in compartment category:

Showing 1 to 14 of 14 entries
enrichment   p-value GO term description
1.77 1.86e-02 GO:0044449 contractile fiber part
1.73 3.30e-03 GO:0005912 adherens junction
1.67 6.05e-03 GO:0070161 anchoring junction
1.47 7.94e-04 GO:0045202 synapse
1.34 7.60e-03 GO:0030054 cell junction
1.20 1.81e-02 GO:0005856 cytoskeleton
1.19 5.81e-06 GO:0043234 protein complex
1.16 1.49e-02 GO:0044459 plasma membrane part
1.12 4.60e-02 GO:0032991 macromolecular complex
1.09 9.36e-03 GO:0005634 nucleus
1.06 2.16e-05 GO:0044424 intracellular part
1.06 7.36e-05 GO:0005622 intracellular
1.06 1.80e-02 GO:0043226 organelle
1.06 2.62e-02 GO:0043229 intracellular organelle

Gene overrepresentation in function category:

Showing 1 to 18 of 18 entries
enrichment   p-value GO term description
1.58 1.85e-02 GO:0000975 regulatory region DNA binding
1.58 1.85e-02 GO:0001067 regulatory region nucleic acid binding
1.58 1.85e-02 GO:0044212 transcription regulatory region DNA binding
1.58 2.97e-02 GO:0010843 promoter binding
1.57 3.49e-04 GO:0016564 transcription repressor activity
1.55 3.50e-10 GO:0043565 sequence-specific DNA binding
1.53 8.23e-03 GO:0032403 protein complex binding
1.46 1.31e-10 GO:0001071 nucleic acid binding transcription factor activity
1.46 1.31e-10 GO:0003700 sequence-specific DNA binding transcription factor activity
1.45 3.59e-02 GO:0016563 transcription activator activity
1.44 6.30e-10 GO:0030528 transcription regulator activity
1.43 3.72e-03 GO:0019904 protein domain specific binding
1.41 2.69e-02 GO:0000988 protein binding transcription factor activity
1.41 2.69e-02 GO:0000989 transcription factor binding transcription factor activity
1.41 3.87e-02 GO:0003712 transcription cofactor activity
1.36 2.34e-04 GO:0019899 enzyme binding
1.15 4.22e-15 GO:0005515 protein binding
1.07 6.40e-10 GO:0005488 binding