Motif ID: MAZ.p2

Z-value: 2.740


Transcription factors associated with MAZ.p2:

Gene SymbolEntrez IDGene Name
MAZ 4150 MYC-associated zinc finger protein (purine-binding transcription factor)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MAZchr16_+_297253110.792.5e-04Click!


Activity profile for motif MAZ.p2.

activity profile for motif MAZ.p2


Sorted Z-values histogram for motif MAZ.p2

Sorted Z-values for motif MAZ.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MAZ.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_26895108 4.806 NM_006015
NM_139135
 ARID1A

AT rich interactive domain 1A (SWI-like)

chr17_-_39652449 3.311 NM_001076684
 UBTF
upstream binding transcription factor, RNA polymerase I
chr20_-_34635091 3.037


chr8_+_144706699 2.924 NM_001166237
 GSDMD
gasdermin D
chr5_+_139008209 2.887 NM_016463
 CXXC5
CXXC finger protein 5
chr2_-_25328452 2.802 NM_153759
 DNMT3A
DNA (cytosine-5-)-methyltransferase 3 alpha
chr17_-_39652391 2.730 UBTF
upstream binding transcription factor, RNA polymerase I
chr10_+_31648103 2.724 NM_001174093
NM_001174095
NM_001174096
NM_030751
 ZEB1



zinc finger E-box binding homeobox 1



chr20_+_34635362 2.657 NM_021809
 TGIF2
TGFB-induced factor homeobox 2
chrX_+_9392980 2.647 NM_005647
 TBL1X
transducin (beta)-like 1X-linked
chr14_-_21064182 2.594 SALL2
sal-like 2 (Drosophila)
chr6_+_149680747 2.538 TAB2
TGF-beta activated kinase 1/MAP3K7 binding protein 2
chr20_+_61841662 2.532 SLC2A4RG
SLC2A4 regulator
chr10_+_76256305 2.382 NM_012330
 MYST4
MYST histone acetyltransferase (monocytic leukemia) 4
chr16_+_49139694 1.950 NM_033119
 NKD1
naked cuticle homolog 1 (Drosophila)
chr1_+_153241665 1.940 NM_015872
 ZBTB7B
zinc finger and BTB domain containing 7B
chr20_+_61841553 1.933 NM_020062
 SLC2A4RG
SLC2A4 regulator
chr19_-_55524445 1.887 NM_004977
 KCNC3
potassium voltage-gated channel, Shaw-related subfamily, member 3
chr6_+_7052985 1.872 NM_001003698
NM_001003699
NM_001003700
 RREB1


ras responsive element binding protein 1


chr9_+_139566129 1.851 NM_032477
 MRPL41
mitochondrial ribosomal protein L41

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 105 entries
enrichment   p-value GO term description
1.79 7.15e-04 GO:0018393 internal peptidyl-lysine acetylation
1.78 1.29e-03 GO:0016573 histone acetylation
1.76 1.60e-03 GO:0018394 peptidyl-lysine acetylation
1.73 3.43e-03 GO:0006475 internal protein amino acid acetylation
1.71 1.91e-03 GO:0006338 chromatin remodeling
1.52 3.40e-05 GO:0016569 covalent chromatin modification
1.52 4.99e-05 GO:0016570 histone modification
1.50 2.81e-11 GO:0016568 chromatin modification
1.41 4.76e-12 GO:0010629 negative regulation of gene expression
1.40 4.84e-10 GO:0045892 negative regulation of transcription, DNA-dependent
1.40 4.04e-07 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.40 5.30e-03 GO:0048011 nerve growth factor receptor signaling pathway
1.39 9.44e-10 GO:0051253 negative regulation of RNA metabolic process
1.38 3.30e-11 GO:0010558 negative regulation of macromolecule biosynthetic process
1.38 1.39e-10 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.38 2.03e-10 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.38 2.73e-10 GO:0051172 negative regulation of nitrogen compound metabolic process
1.36 1.81e-10 GO:0009890 negative regulation of biosynthetic process
1.36 1.60e-06 GO:0006325 chromatin organization
1.35 9.36e-10 GO:0031327 negative regulation of cellular biosynthetic process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 37 entries
enrichment   p-value GO term description
2.40 9.62e-03 GO:0016581 NuRD complex
2.15 4.49e-07 GO:0000118 histone deacetylase complex
1.78 2.57e-07 GO:0016585 chromatin remodeling complex
1.76 2.30e-04 GO:0000123 histone acetyltransferase complex
1.74 2.59e-02 GO:0017053 transcriptional repressor complex
1.73 4.70e-03 GO:0034708 methyltransferase complex
1.73 4.70e-03 GO:0035097 histone methyltransferase complex
1.37 2.44e-02 GO:0043025 neuronal cell body
1.36 3.28e-02 GO:0044297 cell body
1.31 2.23e-09 GO:0044451 nucleoplasm part
1.29 3.75e-16 GO:0005654 nucleoplasm
1.26 9.57e-19 GO:0031981 nuclear lumen
1.25 6.36e-21 GO:0070013 intracellular organelle lumen
1.25 6.42e-20 GO:0044428 nuclear part
1.25 1.12e-18 GO:0005829 cytosol
1.25 5.62e-05 GO:0015630 microtubule cytoskeleton
1.24 3.07e-20 GO:0043233 organelle lumen
1.24 2.70e-03 GO:0005694 chromosome
1.23 1.99e-19 GO:0031974 membrane-enclosed lumen
1.23 2.67e-02 GO:0044427 chromosomal part

Gene overrepresentation in function category:

Showing 1 to 20 of 37 entries
enrichment   p-value GO term description
1.78 2.35e-02 GO:0042826 histone deacetylase binding
1.70 5.13e-03 GO:0019902 phosphatase binding
1.64 2.67e-03 GO:0031625 ubiquitin protein ligase binding
1.40 6.18e-03 GO:0003682 chromatin binding
1.38 8.33e-03 GO:0000975 regulatory region DNA binding
1.38 8.33e-03 GO:0001067 regulatory region nucleic acid binding
1.38 8.33e-03 GO:0044212 transcription regulatory region DNA binding
1.38 8.56e-03 GO:0010843 promoter binding
1.37 1.37e-07 GO:0019904 protein domain specific binding
1.35 9.57e-03 GO:0019900 kinase binding
1.33 6.35e-11 GO:0019899 enzyme binding
1.33 3.27e-03 GO:0016879 ligase activity, forming carbon-nitrogen bonds
1.33 1.01e-02 GO:0016881 acid-amino acid ligase activity
1.32 2.78e-09 GO:0043565 sequence-specific DNA binding
1.32 4.26e-02 GO:0019787 small conjugating protein ligase activity
1.31 8.64e-04 GO:0000988 protein binding transcription factor activity
1.31 8.64e-04 GO:0000989 transcription factor binding transcription factor activity
1.31 6.89e-03 GO:0016564 transcription repressor activity
1.31 1.02e-02 GO:0008134 transcription factor binding
1.30 1.14e-03 GO:0003712 transcription cofactor activity