Motif ID: MAZ.p2

Z-value: 2.740


Transcription factors associated with MAZ.p2:

Gene SymbolEntrez IDGene Name
MAZ 4150 MYC-associated zinc finger protein (purine-binding transcription factor)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MAZchr16_+_297253110.792.5e-04Click!


Activity profile for motif MAZ.p2.

activity profile for motif MAZ.p2


Sorted Z-values histogram for motif MAZ.p2

Sorted Z-values for motif MAZ.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MAZ.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_26895108 4.806 NM_006015
NM_139135
ARID1A

AT rich interactive domain 1A (SWI-like)

chr17_-_39652449 3.311 NM_001076684
UBTF
upstream binding transcription factor, RNA polymerase I
chr20_-_34635091 3.037


chr8_+_144706699 2.924 NM_001166237
GSDMD
gasdermin D
chr5_+_139008209 2.887 NM_016463
CXXC5
CXXC finger protein 5
chr2_-_25328452 2.802 NM_153759
DNMT3A
DNA (cytosine-5-)-methyltransferase 3 alpha
chr17_-_39652391 2.730 UBTF
upstream binding transcription factor, RNA polymerase I
chr10_+_31648103 2.724 NM_001174093
NM_001174095
NM_001174096
NM_030751
ZEB1



zinc finger E-box binding homeobox 1



chr20_+_34635362 2.657 NM_021809
TGIF2
TGFB-induced factor homeobox 2
chrX_+_9392980 2.647 NM_005647
TBL1X
transducin (beta)-like 1X-linked
chr14_-_21064182 2.594 SALL2
sal-like 2 (Drosophila)
chr6_+_149680747 2.538 TAB2
TGF-beta activated kinase 1/MAP3K7 binding protein 2
chr20_+_61841662 2.532 SLC2A4RG
SLC2A4 regulator
chr10_+_76256305 2.382 NM_012330
MYST4
MYST histone acetyltransferase (monocytic leukemia) 4
chr16_+_49139694 1.950 NM_033119
NKD1
naked cuticle homolog 1 (Drosophila)
chr1_+_153241665 1.940 NM_015872
ZBTB7B
zinc finger and BTB domain containing 7B
chr20_+_61841553 1.933 NM_020062
SLC2A4RG
SLC2A4 regulator
chr19_-_55524445 1.887 NM_004977
KCNC3
potassium voltage-gated channel, Shaw-related subfamily, member 3
chr6_+_7052985 1.872 NM_001003698
NM_001003699
NM_001003700
RREB1


ras responsive element binding protein 1


chr9_+_139566129 1.851 NM_032477
MRPL41
mitochondrial ribosomal protein L41
chr2_-_171725150 1.841 TLK1
tousled-like kinase 1
chr1_-_32574185 1.802 NM_023009
MARCKSL1
MARCKS-like 1
chr6_+_169866714 1.776 LOC729088
hypothetical LOC729088
chr5_+_139008667 1.770 CXXC5
CXXC finger protein 5
chr7_-_51351825 1.754 COBL
cordon-bleu homolog (mouse)
chr10_-_135021502 1.746 NM_001098483
NM_198472
C10orf125

chromosome 10 open reading frame 125

chr7_-_100325209 1.746 NM_001015072
UFSP1
UFM1-specific peptidase 1 (non-functional)
chr11_-_67737275 1.733 NM_016028
NM_017635
SUV420H1

suppressor of variegation 4-20 homolog 1 (Drosophila)

chr19_+_1200882 1.726 MIDN
midnolin
chr15_-_80125403 1.724 NM_032246
MEX3B
mex-3 homolog B (C. elegans)
chr6_+_7053183 1.715 RREB1
ras responsive element binding protein 1
chr15_-_80125514 1.705 MEX3B
mex-3 homolog B (C. elegans)
chr6_+_7052798 1.687 NM_001168344
RREB1
ras responsive element binding protein 1
chr1_+_153241858 1.680 ZBTB7B
zinc finger and BTB domain containing 7B
chr17_-_20886680 1.677 NM_015276
USP22
ubiquitin specific peptidase 22
chrX_+_138060 1.672 NM_018390
PLCXD1
phosphatidylinositol-specific phospholipase C, X domain containing 1
chr2_-_10506033 1.653 ODC1
ornithine decarboxylase 1
chr17_-_39632845 1.649 ATXN7L3
ataxin 7-like 3
chr2_+_220117009 1.645 TMEM198
transmembrane protein 198
chr17_-_53764867 1.642


chr9_-_131845277 1.634 NM_015033
FNBP1
formin binding protein 1
chr3_-_12983959 1.615 NM_014869
IQSEC1
IQ motif and Sec7 domain 1
chr7_+_149707338 1.581 NM_173680
ZNF775
zinc finger protein 775
chr17_-_1336073 1.568 MYO1C
myosin IC
chr14_-_76564374 1.552 IRF2BPL
interferon regulatory factor 2 binding protein-like
chr1_+_209499478 1.548 RCOR3
REST corepressor 3
chr2_-_174537021 1.527 NM_001017371
SP3
Sp3 transcription factor
chr1_-_233879617 1.524 NM_001098722
GNG4
guanine nucleotide binding protein (G protein), gamma 4
chr2_+_220116986 1.516 NM_001005209
TMEM198
transmembrane protein 198
chr19_+_10574055 1.515 NM_001145056
SLC44A2
solute carrier family 44, member 2
chr17_-_34157962 1.514 NM_007144
PCGF2
polycomb group ring finger 2
chr7_-_51351952 1.499 NM_015198
COBL
cordon-bleu homolog (mouse)
chr2_-_174537354 1.496 SP3
Sp3 transcription factor
chr17_-_4792433 1.475 PFN1
profilin 1
chr1_+_3679168 1.445 NM_001163724
LOC388588
hypothetical protein LOC388588
chr5_+_139008139 1.438 CXXC5
CXXC finger protein 5
chr19_-_14062230 1.435 NM_138352
SAMD1
sterile alpha motif domain containing 1
chr9_+_70509925 1.434 NM_003558
PIP5K1B
phosphatidylinositol-4-phosphate 5-kinase, type I, beta
chr7_+_137795719 1.433 TRIM24
tripartite motif containing 24
chr16_-_960796 1.419 LMF1
lipase maturation factor 1
chr16_-_960982 1.396 NM_022773
LMF1
lipase maturation factor 1
chr14_-_88953059 1.390 NM_005197
FOXN3
forkhead box N3
chr15_-_32875040 1.389 NM_005159
ACTC1
actin, alpha, cardiac muscle 1
chr1_+_209499349 1.386 RCOR3
REST corepressor 3
chr21_+_37661063 1.383 DYRK1A
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
chr5_-_175896829 1.381 NM_014901
RNF44
ring finger protein 44
chr15_-_72513053 1.380 NM_001146030
SEMA7A
semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
chr11_+_117812282 1.374 NM_001197104
NM_005933
MLL

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)

chr16_+_2503676 1.372 NM_001198569
NM_001694
ATP6V0C

ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c

chr4_-_6253152 1.371 NM_001099433
NM_144720
JAKMIP1

janus kinase and microtubule interacting protein 1

chr6_+_163755788 1.359 QKI
quaking homolog, KH domain RNA binding (mouse)
chr6_-_25019173 1.357 NM_014722
FAM65B
family with sequence similarity 65, member B
chr5_+_176446425 1.354 NM_002011
NM_213647
FGFR4

fibroblast growth factor receptor 4

chr15_-_20637731 1.333 NM_144599
NIPA1
non imprinted in Prader-Willi/Angelman syndrome 1
chrX_-_2428579 1.329 NM_001171135
ZBED1
zinc finger, BED-type containing 1
chr1_+_165865953 1.328 NM_052862
RCSD1
RCSD domain containing 1
chr20_+_56900116 1.319 NM_001077488
GNAS
GNAS complex locus
chr1_+_209499355 1.313 RCOR3
REST corepressor 3
chr2_-_74634569 1.310 NM_032603
LOXL3
lysyl oxidase-like 3
chr2_-_10505902 1.302 NM_002539
ODC1
ornithine decarboxylase 1
chr5_+_139008091 1.298 CXXC5
CXXC finger protein 5
chr2_+_232281470 1.297 NM_001099285
NM_002823
PTMA

prothymosin, alpha

chr2_+_232281491 1.297 PTMA
prothymosin, alpha
chr7_+_149696901 1.290 REPIN1
replication initiator 1
chr19_+_40451807 1.269 USF2
upstream transcription factor 2, c-fos interacting
chr9_-_131845077 1.266 FNBP1
formin binding protein 1
chr9_+_114289178 1.262 KIAA1958
KIAA1958
chr2_-_200030944 1.254 NM_001172509
SATB2
SATB homeobox 2
chr2_+_242322645 1.253 NM_152783
D2HGDH
D-2-hydroxyglutarate dehydrogenase
chr19_-_52307325 1.252 ZC3H4
zinc finger CCCH-type containing 4
chr8_+_81560971 1.251 NM_001105539
NM_023929
ZBTB10

zinc finger and BTB domain containing 10

chr15_+_38550451 1.251 NM_130468
CHST14
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14
chr10_-_31647925 1.247 LOC220930
hypothetical LOC220930
chr17_-_41626032 1.247 NM_015443
KIAA1267
KIAA1267
chr18_-_28606839 1.245 NM_020805
KLHL14
kelch-like 14 (Drosophila)
chr1_-_1233109 1.228 NM_030649
ACAP3
ArfGAP with coiled-coil, ankyrin repeat and PH domains 3
chr17_-_4792572 1.227 PFN1
profilin 1
chr17_-_73636362 1.225 TMC6
transmembrane channel-like 6
chr22_-_17545872 1.222 SLC25A1
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr6_+_163755658 1.221 NM_006775
NM_206853
NM_206854
NM_206855
QKI



quaking homolog, KH domain RNA binding (mouse)



chr8_-_80842452 1.219 NM_001040708
NM_012258
HEY1

hairy/enhancer-of-split related with YRPW motif 1

chr1_+_209499908 1.218 NM_018254
RCOR3
REST corepressor 3
chr17_-_1029758 1.217 NM_021962
ABR
active BCR-related gene
chr20_+_35407872 1.215 NM_198291
SRC
v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
chr1_+_945399 1.205


chr1_+_165866127 1.201 RCSD1
RCSD domain containing 1
chr7_+_5289079 1.199 NM_001040661
NM_153247
SLC29A4

solute carrier family 29 (nucleoside transporters), member 4

chr3_+_20056527 1.183 NM_003884
KAT2B
K(lysine) acetyltransferase 2B
chr15_-_63457378 1.180 NM_004884
IGDCC3
immunoglobulin superfamily, DCC subclass, member 3
chr12_+_49443903 1.178 NM_005171
ATF1
activating transcription factor 1
chr22_-_40652724 1.178 NM_052945
TNFRSF13C
tumor necrosis factor receptor superfamily, member 13C
chr2_+_200031333 1.178


chr17_-_59131210 1.169 NM_030576
LIMD2
LIM domain containing 2
chr6_+_42858443 1.166 FLJ38717
FLJ38717 protein
chr20_+_61374603 1.160 NM_018209
NM_175609
ARFGAP1

ADP-ribosylation factor GTPase activating protein 1

chr17_+_73676219 1.153 NM_004710
SYNGR2
synaptogyrin 2
chr19_+_40451842 1.150 USF2
upstream transcription factor 2, c-fos interacting
chr17_-_59131194 1.150 LIMD2
LIM domain containing 2
chr5_+_149845503 1.145 NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr19_+_4229597 1.143 NM_020209
SHD
Src homology 2 domain containing transforming protein D
chr17_-_35331435 1.143 ORMDL3
ORM1-like 3 (S. cerevisiae)
chr2_+_218972721 1.141 NM_021198
CTDSP1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr9_-_125732005 1.140 NM_020946
NM_024820
DENND1A

DENN/MADD domain containing 1A

chr1_+_209499316 1.140 NM_001136223
NM_001136224
NM_001136225
RCOR3


REST corepressor 3


chr12_+_56291484 1.139 NM_182947
ARHGEF25
Rho guanine nucleotide exchange factor (GEF) 25
chr6_-_144427340 1.138 NM_001080951
NM_001080955
PLAGL1

pleiomorphic adenoma gene-like 1

chr1_+_26671548 1.132 HMGN2
high-mobility group nucleosomal binding domain 2
chr4_+_38341982 1.131 NM_016531
KLF3
Kruppel-like factor 3 (basic)
chr19_+_1199548 1.126 NM_177401
MIDN
midnolin
chr6_-_151754337 1.123 NM_020861
ZBTB2
zinc finger and BTB domain containing 2
chr10_+_135042684 1.123 NM_152911
NM_207127
NM_207128
PAOX


polyamine oxidase (exo-N4-amino)


chr16_-_51138306 1.121 NM_001080430
TOX3
TOX high mobility group box family member 3
chr6_+_163755773 1.119 QKI
quaking homolog, KH domain RNA binding (mouse)
chr17_+_34114924 1.105 MLLT6
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr9_-_91302707 1.103 SEMA4D
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
chr18_-_71050034 1.101 ZADH2
zinc binding alcohol dehydrogenase domain containing 2
chr20_-_30534848 1.095 NM_080616
C20orf112
chromosome 20 open reading frame 112
chr17_-_4792542 1.094 NM_005022
PFN1
profilin 1
chr18_-_24010944 1.093 CDH2
cadherin 2, type 1, N-cadherin (neuronal)
chr12_+_93066370 1.089 NM_005761
PLXNC1
plexin C1
chr5_+_179165957 1.088 NM_001142298
SQSTM1
sequestosome 1
chr20_-_17610828 1.087 NM_001042576
NM_004587
RRBP1

ribosome binding protein 1 homolog 180kDa (dog)

chr16_+_2503915 1.085 ATP6V0C
ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
chr1_+_945331 1.079 NM_198576
AGRN
agrin
chr20_+_56899904 1.074 GNAS
GNAS complex locus
chr8_-_71478560 1.074 NM_006540
NCOA2
nuclear receptor coactivator 2
chr6_-_41810712 1.073 NM_007162
TFEB
transcription factor EB
chr7_-_102044374 1.068 RASA4
RAS p21 protein activator 4
chr20_-_61755145 1.066 NM_015894
STMN3
stathmin-like 3
chr4_-_105635499 1.065 CXXC4
CXXC finger protein 4
chr7_+_137795387 1.054 NM_003852
NM_015905
TRIM24

tripartite motif containing 24

chr19_+_40451720 1.052 NM_003367
NM_207291
USF2

upstream transcription factor 2, c-fos interacting

chr1_+_35507197 1.052 ZMYM4
zinc finger, MYM-type 4
chr14_-_23090606 1.050 NM_033400
ZFHX2
zinc finger homeobox 2
chr17_+_75366524 1.048 NM_005189
NM_032647
CBX2

chromobox homolog 2

chr2_+_119905812 1.045 NM_183240
TMEM37
transmembrane protein 37
chr14_-_20562962 1.044 NM_201538
NM_201539
NM_201540
NM_201541
NDRG2



NDRG family member 2



chr16_-_371823 1.041 NM_021259
TMEM8A
transmembrane protein 8A
chr6_-_32265489 1.040 NM_002586
PBX2
pre-B-cell leukemia homeobox 2
chr17_-_60986905 1.030 AXIN2
axin 2
chr6_-_86409415 1.030 SYNCRIP
synaptotagmin binding, cytoplasmic RNA interacting protein
chr18_-_71050268 1.030 NM_175907
ZADH2
zinc binding alcohol dehydrogenase domain containing 2
chr17_-_1335763 1.029 NM_001080950
MYO1C
myosin IC
chr2_+_219780192 1.026 ZFAND2B
zinc finger, AN1-type domain 2B
chr2_+_219779737 1.024 NM_138802
ZFAND2B
zinc finger, AN1-type domain 2B
chr19_+_748390 1.020 NM_002819
NM_031990
NM_031991
NM_175847
PTBP1



polypyrimidine tract binding protein 1



chr5_-_179166378 1.018 NM_014275
MGAT4B
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B
chr2_-_61551403 1.015 USP34
ubiquitin specific peptidase 34
chr4_+_57469122 1.013 REST
RE1-silencing transcription factor
chr14_+_104261578 1.011 NM_152328
ADSSL1
adenylosuccinate synthase like 1
chr12_-_61614930 1.009 NM_020700
PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr20_-_62071584 1.008 NM_020713
ZNF512B
zinc finger protein 512B
chr15_+_39739933 1.007 MGA
MAX gene associated
chr6_+_149681128 1.006 NM_015093
TAB2
TGF-beta activated kinase 1/MAP3K7 binding protein 2
chr1_-_149698516 1.002 NM_001194937
NM_001194938
NM_015100
NM_145796
POGZ



pogo transposable element with ZNF domain



chr18_-_71049977 0.995


chr8_-_117956226 0.994 NM_006265
RAD21
RAD21 homolog (S. pombe)
chrX_+_118776572 0.993 NM_001105576
ANKRD58
ankyrin repeat domain 58
chr2_+_242289983 0.992 NM_032329
ING5
inhibitor of growth family, member 5
chr14_+_23670514 0.987 NM_203402
FITM1
fat storage-inducing transmembrane protein 1
chr2_-_47986160 0.987 NM_001190274
FBXO11
F-box protein 11
chr16_-_1369613 0.984 NM_001193389
NM_023076
UNKL

unkempt homolog (Drosophila)-like

chr1_+_26671488 0.983 NM_005517
HMGN2
high-mobility group nucleosomal binding domain 2
chr17_-_45582872 0.979 NM_032595
PPP1R9B
protein phosphatase 1, regulatory (inhibitor) subunit 9B
chr22_-_16636748 0.977 NM_197966
BID
BH3 interacting domain death agonist
chr7_-_86942910 0.975 NM_000443
NM_018849
NM_018850
ABCB4


ATP-binding cassette, sub-family B (MDR/TAP), member 4


chr1_-_23393808 0.973 NM_000864
HTR1D
5-hydroxytryptamine (serotonin) receptor 1D
chr6_-_165996031 0.968 LOC100132188
LP7097
chr17_-_77824529 0.968 CSNK1D
casein kinase 1, delta
chr9_+_139619957 0.968 ARRDC1
arrestin domain containing 1
chr2_+_218972963 0.967 NM_182642
CTDSP1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr19_-_44060729 0.966 NM_001195833
NM_198445
RINL

Ras and Rab interactor-like

chr21_-_43671355 0.964 NM_173354
SIK1
salt-inducible kinase 1
chr19_+_1226510 0.964 NM_017914
C19orf24
chromosome 19 open reading frame 24
chr2_+_74635019 0.961 NM_001381
DOK1
docking protein 1, 62kDa (downstream of tyrosine kinase 1)
chr19_+_3310138 0.960 NM_205843
NFIC
nuclear factor I/C (CCAAT-binding transcription factor)
chr9_+_114288899 0.958 NM_133465
KIAA1958
KIAA1958
chr19_+_59333287 0.958 CNOT3
CCR4-NOT transcription complex, subunit 3
chr10_-_75304225 0.957 NM_001222
NM_172169
NM_172171
NM_172173
NM_172170
CAMK2G




calcium/calmodulin-dependent protein kinase II gamma




chr19_+_59333232 0.956 NM_014516
CNOT3
CCR4-NOT transcription complex, subunit 3

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.07 5.12e-20 GO:0009987 cellular process
1.15 2.08e-16 GO:0044260 cellular macromolecule metabolic process
1.12 5.08e-16 GO:0044237 cellular metabolic process
1.18 1.23e-15 GO:0060255 regulation of macromolecule metabolic process
1.11 1.51e-14 GO:0050794 regulation of cellular process
1.33 1.93e-13 GO:0009892 negative regulation of metabolic process
1.34 2.75e-13 GO:0010605 negative regulation of macromolecule metabolic process
1.16 2.84e-13 GO:0031323 regulation of cellular metabolic process
1.10 3.26e-13 GO:0050789 regulation of biological process
1.16 4.66e-13 GO:0080090 regulation of primary metabolic process
1.11 5.26e-13 GO:0044238 primary metabolic process
1.15 2.42e-12 GO:0019222 regulation of metabolic process
1.10 3.81e-12 GO:0008152 metabolic process
1.41 4.76e-12 GO:0010629 negative regulation of gene expression
1.33 5.89e-12 GO:0031324 negative regulation of cellular metabolic process
1.19 6.22e-12 GO:0010468 regulation of gene expression
1.12 9.59e-12 GO:0043170 macromolecule metabolic process
1.09 1.35e-11 GO:0065007 biological regulation
1.50 2.81e-11 GO:0016568 chromatin modification
1.38 3.30e-11 GO:0010558 negative regulation of macromolecule biosynthetic process
1.17 4.87e-11 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.38 1.39e-10 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.36 1.81e-10 GO:0009890 negative regulation of biosynthetic process
1.19 1.81e-10 GO:0090304 nucleic acid metabolic process
1.16 1.89e-10 GO:0034641 cellular nitrogen compound metabolic process
1.18 1.94e-10 GO:0048519 negative regulation of biological process
1.38 2.03e-10 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.38 2.73e-10 GO:0051172 negative regulation of nitrogen compound metabolic process
1.29 4.76e-10 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.40 4.84e-10 GO:0045892 negative regulation of transcription, DNA-dependent
1.18 4.91e-10 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.19 8.66e-10 GO:0048523 negative regulation of cellular process
1.35 9.36e-10 GO:0031327 negative regulation of cellular biosynthetic process
1.39 9.44e-10 GO:0051253 negative regulation of RNA metabolic process
1.15 1.16e-09 GO:0016043 cellular component organization
1.17 1.38e-09 GO:0010556 regulation of macromolecule biosynthetic process
1.14 5.00e-09 GO:0006807 nitrogen compound metabolic process
1.18 5.39e-09 GO:0051252 regulation of RNA metabolic process
1.14 9.01e-09 GO:0071840 cellular component organization or biogenesis
1.15 2.42e-08 GO:0051171 regulation of nitrogen compound metabolic process
1.20 3.55e-08 GO:0034645 cellular macromolecule biosynthetic process
1.20 6.33e-08 GO:0016070 RNA metabolic process
1.20 8.01e-08 GO:0009059 macromolecule biosynthetic process
1.17 1.44e-07 GO:0006355 regulation of transcription, DNA-dependent
1.16 1.83e-07 GO:0044249 cellular biosynthetic process
1.16 1.95e-07 GO:0009058 biosynthetic process
1.15 2.15e-07 GO:0071842 cellular component organization at cellular level
1.15 2.35e-07 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.15 3.13e-07 GO:0009889 regulation of biosynthetic process
1.15 3.16e-07 GO:0031326 regulation of cellular biosynthetic process
1.16 3.29e-07 GO:0048522 positive regulation of cellular process
1.40 4.04e-07 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.27 5.09e-07 GO:0006351 transcription, DNA-dependent
1.14 6.07e-07 GO:0071841 cellular component organization or biogenesis at cellular level
1.36 1.60e-06 GO:0006325 chromatin organization
1.26 2.14e-06 GO:0016265 death
1.15 2.42e-06 GO:0044267 cellular protein metabolic process
1.24 3.42e-06 GO:0032268 regulation of cellular protein metabolic process
1.26 3.58e-06 GO:0008219 cell death
1.17 3.91e-06 GO:0010467 gene expression
1.23 4.85e-06 GO:0051246 regulation of protein metabolic process
1.14 8.41e-06 GO:0048518 positive regulation of biological process
1.32 1.30e-05 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.16 1.38e-05 GO:0043412 macromolecule modification
1.23 2.85e-05 GO:0032774 RNA biosynthetic process
1.52 3.40e-05 GO:0016569 covalent chromatin modification
1.16 4.91e-05 GO:0006464 protein modification process
1.52 4.99e-05 GO:0016570 histone modification
1.17 1.82e-04 GO:0007399 nervous system development
1.27 1.85e-04 GO:0007167 enzyme linked receptor protein signaling pathway
1.21 1.99e-04 GO:0007049 cell cycle
1.25 3.28e-04 GO:0012501 programmed cell death
1.16 3.98e-04 GO:0006996 organelle organization
1.26 4.12e-04 GO:0051276 chromosome organization
1.24 5.86e-04 GO:0006915 apoptosis
1.79 7.15e-04 GO:0018393 internal peptidyl-lysine acetylation
1.17 1.09e-03 GO:0009966 regulation of signal transduction
1.78 1.29e-03 GO:0016573 histone acetylation
1.76 1.60e-03 GO:0018394 peptidyl-lysine acetylation
1.71 1.91e-03 GO:0006338 chromatin remodeling
1.22 1.94e-03 GO:0031399 regulation of protein modification process
1.15 2.65e-03 GO:0023051 regulation of signaling
1.73 3.43e-03 GO:0006475 internal protein amino acid acetylation
1.16 4.01e-03 GO:0033036 macromolecule localization
1.09 4.29e-03 GO:0032502 developmental process
1.09 4.48e-03 GO:0051179 localization
1.40 5.30e-03 GO:0048011 nerve growth factor receptor signaling pathway
1.10 6.55e-03 GO:0019538 protein metabolic process
1.30 1.25e-02 GO:0044419 interspecies interaction between organisms
1.27 1.34e-02 GO:0045859 regulation of protein kinase activity
1.31 1.37e-02 GO:0012502 induction of programmed cell death
1.22 1.40e-02 GO:0030182 neuron differentiation
1.26 1.66e-02 GO:0043549 regulation of kinase activity
1.30 1.81e-02 GO:0006917 induction of apoptosis
1.19 1.92e-02 GO:0048699 generation of neurons
1.34 2.01e-02 GO:0010608 posttranscriptional regulation of gene expression
1.10 2.08e-02 GO:0051234 establishment of localization
1.19 2.19e-02 GO:0022008 neurogenesis
1.33 2.35e-02 GO:0006366 transcription from RNA polymerase II promoter
1.10 3.21e-02 GO:0006810 transport
1.25 3.22e-02 GO:0051338 regulation of transferase activity
1.15 3.28e-02 GO:0051641 cellular localization
1.22 4.39e-02 GO:0030030 cell projection organization
1.09 4.41e-02 GO:0007275 multicellular organismal development
1.17 4.75e-02 GO:0010941 regulation of cell death

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.11 5.07e-59 GO:0044424 intracellular part
1.11 2.91e-58 GO:0005622 intracellular
1.12 1.24e-39 GO:0043226 organelle
1.12 1.47e-39 GO:0043229 intracellular organelle
1.14 2.98e-39 GO:0005737 cytoplasm
1.13 3.56e-39 GO:0043227 membrane-bounded organelle
1.13 6.01e-39 GO:0043231 intracellular membrane-bounded organelle
1.17 7.48e-31 GO:0005634 nucleus
1.14 2.97e-23 GO:0044444 cytoplasmic part
1.25 6.36e-21 GO:0070013 intracellular organelle lumen
1.24 3.07e-20 GO:0043233 organelle lumen
1.25 6.42e-20 GO:0044428 nuclear part
1.23 1.99e-19 GO:0031974 membrane-enclosed lumen
1.26 9.57e-19 GO:0031981 nuclear lumen
1.25 1.12e-18 GO:0005829 cytosol
1.13 8.46e-18 GO:0044422 organelle part
1.13 1.00e-17 GO:0044446 intracellular organelle part
1.29 3.75e-16 GO:0005654 nucleoplasm
1.03 1.04e-10 GO:0005623 cell
1.03 1.28e-10 GO:0044464 cell part
1.31 2.23e-09 GO:0044451 nucleoplasm part
1.13 2.32e-07 GO:0043234 protein complex
1.78 2.57e-07 GO:0016585 chromatin remodeling complex
2.15 4.49e-07 GO:0000118 histone deacetylase complex
1.12 5.90e-07 GO:0032991 macromolecular complex
1.13 2.49e-06 GO:0043228 non-membrane-bounded organelle
1.13 2.49e-06 GO:0043232 intracellular non-membrane-bounded organelle
1.25 5.62e-05 GO:0015630 microtubule cytoskeleton
1.76 2.30e-04 GO:0000123 histone acetyltransferase complex
1.24 2.70e-03 GO:0005694 chromosome
1.73 4.70e-03 GO:0034708 methyltransferase complex
1.73 4.70e-03 GO:0035097 histone methyltransferase complex
2.40 9.62e-03 GO:0016581 NuRD complex
1.37 2.44e-02 GO:0043025 neuronal cell body
1.74 2.59e-02 GO:0017053 transcriptional repressor complex
1.23 2.67e-02 GO:0044427 chromosomal part
1.36 3.28e-02 GO:0044297 cell body

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.15 2.04e-36 GO:0005515 protein binding
1.08 1.03e-30 GO:0005488 binding
1.15 2.03e-11 GO:0003676 nucleic acid binding
1.33 6.35e-11 GO:0019899 enzyme binding
1.17 1.52e-09 GO:0003677 DNA binding
1.32 2.78e-09 GO:0043565 sequence-specific DNA binding
1.25 8.74e-08 GO:0001071 nucleic acid binding transcription factor activity
1.25 8.74e-08 GO:0003700 sequence-specific DNA binding transcription factor activity
1.37 1.37e-07 GO:0019904 protein domain specific binding
1.23 1.34e-06 GO:0030528 transcription regulator activity
1.12 4.77e-04 GO:0000166 nucleotide binding
1.31 8.64e-04 GO:0000988 protein binding transcription factor activity
1.31 8.64e-04 GO:0000989 transcription factor binding transcription factor activity
1.30 1.14e-03 GO:0003712 transcription cofactor activity
1.20 1.68e-03 GO:0003723 RNA binding
1.64 2.67e-03 GO:0031625 ubiquitin protein ligase binding
1.12 2.84e-03 GO:0008270 zinc ion binding
1.33 3.27e-03 GO:0016879 ligase activity, forming carbon-nitrogen bonds
1.70 5.13e-03 GO:0019902 phosphatase binding
1.40 6.18e-03 GO:0003682 chromatin binding
1.31 6.89e-03 GO:0016564 transcription repressor activity
1.38 8.33e-03 GO:0000975 regulatory region DNA binding
1.38 8.33e-03 GO:0001067 regulatory region nucleic acid binding
1.38 8.33e-03 GO:0044212 transcription regulatory region DNA binding
1.38 8.56e-03 GO:0010843 promoter binding
1.08 9.25e-03 GO:0046872 metal ion binding
1.35 9.57e-03 GO:0019900 kinase binding
1.33 1.01e-02 GO:0016881 acid-amino acid ligase activity
1.31 1.02e-02 GO:0008134 transcription factor binding
1.08 1.71e-02 GO:0043169 cation binding
1.19 1.71e-02 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.08 2.33e-02 GO:0043167 ion binding
1.78 2.35e-02 GO:0042826 histone deacetylase binding
1.18 2.98e-02 GO:0016301 kinase activity
1.18 3.82e-02 GO:0042802 identical protein binding
1.32 4.26e-02 GO:0019787 small conjugating protein ligase activity
1.10 4.47e-02 GO:0046914 transition metal ion binding