Motif ID: MEF2{A,B,C,D}.p2

Z-value: 1.958


Transcription factors associated with MEF2{A,B,C,D}.p2:

Gene SymbolEntrez IDGene Name
MEF2A 4205 myocyte enhancer factor 2A
MEF2B 100271849 myocyte enhancer factor 2B
MEF2BNB-MEF2B 4207 MEF2BNB-MEF2B readthrough
MEF2C 4208 myocyte enhancer factor 2C
MEF2D 4209 myocyte enhancer factor 2D

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MEF2Dchr1_-_1547371620.552.8e-02Click!
MEF2Cchr5_-_882150340.524.0e-02Click!
LOC729991-MEF2Bchr19_-_19163916-0.361.7e-01Click!
MEF2Achr15_+_97990705-0.341.9e-01Click!
MEF2Bchr19_-_19142090-0.009.9e-01Click!


Activity profile for motif MEF2{A,B,C,D}.p2.

activity profile for motif MEF2{A,B,C,D}.p2


Sorted Z-values histogram for motif MEF2{A,B,C,D}.p2

Sorted Z-values for motif MEF2{A,B,C,D}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MEF2{A,B,C,D}.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_-_111119846 4.671 NM_001142483
 C5orf13
chromosome 5 open reading frame 13
chr10_+_69539255 4.493 NM_032578
 MYPN
myopalladin
chr12_+_79625538 4.207 NM_002469
 MYF6
myogenic factor 6 (herculin)
chr10_-_75080784 3.997 NM_024875
 SYNPO2L
synaptopodin 2-like
chr10_-_75085754 3.809 NM_001114133
 SYNPO2L
synaptopodin 2-like
chr2_+_88148413 3.370 NM_198274
 SMYD1
SET and MYND domain containing 1
chr2_-_105421661 3.059 NM_201557
 FHL2
four and a half LIM domains 2
chr4_+_169654742 3.053 NM_001166108
NM_016081
 PALLD

palladin, cytoskeletal associated protein

chr8_+_67201684 3.009 NM_033058
NM_184085
NM_184086
NM_184087
 TRIM55



tripartite motif containing 55



chr5_+_155686333 2.952 NM_000337
NM_001128209
NM_172244
 SGCD


sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)


chr5_+_53787187 2.695 NM_006308
 HSPB3
heat shock 27kDa protein 3
chrX_-_77801480 2.623 NM_152694
 ZCCHC5
zinc finger, CCHC domain containing 5
chr16_+_31132842 2.596 NM_001008274
 TRIM72
tripartite motif containing 72
chr6_-_139654807 2.539 NM_153235
 TXLNB
taxilin beta
chr2_+_170074457 2.498 NM_006063
 KBTBD10
kelch repeat and BTB (POZ) domain containing 10
chr15_-_68781662 2.300 NM_001008224
 UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr3_-_39209075 2.271 NM_194293
NM_001198621
 XIRP1

xin actin-binding repeat containing 1

chr10_+_111755715 2.238 NM_019903
 ADD3
adducin 3 (gamma)
chr1_-_199657468 2.202 NM_003281
 TNNI1
troponin I type 1 (skeletal, slow)
chr11_-_85107569 2.074 NM_206929
 SYTL2
synaptotagmin-like 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 9 of 9 entries
enrichment   p-value GO term description
2.41 7.38e-03 GO:0007517 muscle organ development
2.33 3.92e-02 GO:0003012 muscle system process
2.19 4.06e-03 GO:0061061 muscle structure development
2.09 1.30e-02 GO:0030029 actin filament-based process
1.77 4.99e-02 GO:0007606 sensory perception of chemical stimulus
1.57 4.78e-02 GO:0007600 sensory perception
1.40 1.43e-02 GO:0003008 system process
1.21 5.28e-03 GO:0032501 multicellular organismal process
1.17 2.94e-02 GO:0050896 response to stimulus

Gene overrepresentation in compartment category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
4.74 4.87e-04 GO:0030018 Z disc
4.61 4.47e-05 GO:0031674 I band
4.38 2.94e-10 GO:0030017 sarcomere
4.30 8.21e-12 GO:0030016 myofibril
4.17 1.18e-10 GO:0044449 contractile fiber part
4.05 6.08e-11 GO:0043292 contractile fiber
1.53 1.71e-03 GO:0044421 extracellular region part
1.30 3.90e-02 GO:0005576 extracellular region

Gene overrepresentation in function category:

Showing 1 to 4 of 4 entries
enrichment   p-value GO term description
1.78 3.93e-02 GO:0004984 olfactory receptor activity
1.53 2.43e-02 GO:0004930 G-protein coupled receptor activity
1.41 4.07e-02 GO:0004888 transmembrane receptor activity
1.38 8.21e-03 GO:0004872 receptor activity