Motif ID: MYFfamily.p2

Z-value: 1.645


Transcription factors associated with MYFfamily.p2:

Gene SymbolEntrez IDGene Name
MYF5 4617 myogenic factor 5
MYF6 4618 myogenic factor 6 (herculin)
MYOD1 4654 myogenic differentiation 1
MYOG 4656 myogenin (myogenic factor 4)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MYOGchr1_-_2013217110.591.7e-02Click!
MYOD1chr11_+_176976850.572.1e-02Click!
MYF5chr12_+_796348200.523.8e-02Click!
MYF6chr12_+_796255380.514.2e-02Click!


Activity profile for motif MYFfamily.p2.

activity profile for motif MYFfamily.p2


Sorted Z-values histogram for motif MYFfamily.p2

Sorted Z-values for motif MYFfamily.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MYFfamily.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_+_45498354 4.515 RUNX2
runt-related transcription factor 2
chr6_+_45498262 3.396 RUNX2
runt-related transcription factor 2
chr12_-_74710741 2.400 PHLDA1
pleckstrin homology-like domain, family A, member 1
chr6_+_129245978 1.992 NM_000426
NM_001079823
 LAMA2

laminin, alpha 2

chr6_+_107917965 1.825 NM_018013
 SOBP
sine oculis binding protein homolog (Drosophila)
chr4_+_3046034 1.775 NM_002111
 HTT
huntingtin
chr18_+_59788242 1.714 NM_001031848
NM_002640
NM_198833
 SERPINB8


serpin peptidase inhibitor, clade B (ovalbumin), member 8


chr2_-_227372574 1.707 IRS1
insulin receptor substrate 1
chr9_+_35896188 1.670 NM_001039792
 HRCT1
histidine rich carboxyl terminus 1
chr14_+_58174489 1.610 NM_001079520
NM_016651
 DACT1

dapper, antagonist of beta-catenin, homolog 1 (Xenopus laevis)

chr1_-_72521079 1.588


chr5_-_178705036 1.503 NM_014244
NM_021599
 ADAMTS2

ADAM metallopeptidase with thrombospondin type 1 motif, 2

chr3_-_126257425 1.430 NM_020733
 HEG1
HEG homolog 1 (zebrafish)
chr17_+_14145051 1.412 NM_006041
 HS3ST3B1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
chr1_-_56817802 1.402 PPAP2B
phosphatidic acid phosphatase type 2B
chr12_-_74711474 1.392 PHLDA1
pleckstrin homology-like domain, family A, member 1
chr13_-_34948758 1.378 NM_005584
 MAB21L1
mab-21-like 1 (C. elegans)
chr22_+_20068039 1.374 NM_001128635
 RIMBP3B
RIMS binding protein 3B
chr10_+_89409332 1.338 NM_001015880
NM_004670
 PAPSS2

3'-phosphoadenosine 5'-phosphosulfate synthase 2

chr18_-_21185968 1.329 ZNF521
zinc finger protein 521

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 59 entries
enrichment   p-value GO term description
2.97 4.62e-02 GO:0061035 regulation of cartilage development
2.06 4.64e-02 GO:0030326 embryonic limb morphogenesis
2.06 4.64e-02 GO:0035113 embryonic appendage morphogenesis
1.73 3.64e-03 GO:0030168 platelet activation
1.66 4.55e-03 GO:0061061 muscle structure development
1.60 6.31e-03 GO:0007411 axon guidance
1.59 3.76e-02 GO:0001944 vasculature development
1.57 6.07e-04 GO:0048812 neuron projection morphogenesis
1.57 1.19e-03 GO:0007409 axonogenesis
1.55 1.40e-03 GO:0048667 cell morphogenesis involved in neuron differentiation
1.53 9.52e-04 GO:0031175 neuron projection development
1.52 1.04e-03 GO:0000904 cell morphogenesis involved in differentiation
1.51 3.17e-03 GO:0072358 cardiovascular system development
1.51 3.17e-03 GO:0072359 circulatory system development
1.50 3.07e-03 GO:0048858 cell projection morphogenesis
1.49 4.70e-03 GO:0001775 cell activation
1.49 1.66e-02 GO:0051094 positive regulation of developmental process
1.48 5.06e-03 GO:0032990 cell part morphogenesis
1.47 4.55e-04 GO:0007167 enzyme linked receptor protein signaling pathway
1.47 1.86e-03 GO:0048666 neuron development

Gene overrepresentation in compartment category:

Showing 1 to 19 of 19 entries
enrichment   p-value GO term description
2.84 2.29e-03 GO:0005581 collagen
2.52 5.22e-03 GO:0031093 platelet alpha granule lumen
2.47 7.96e-03 GO:0034774 secretory granule lumen
2.38 1.05e-02 GO:0031983 vesicle lumen
2.37 1.76e-02 GO:0060205 cytoplasmic membrane-bounded vesicle lumen
2.23 2.66e-02 GO:0031091 platelet alpha granule
1.96 3.77e-03 GO:0044420 extracellular matrix part
1.84 1.61e-02 GO:0043292 contractile fiber
1.69 1.79e-06 GO:0031012 extracellular matrix
1.66 8.31e-05 GO:0005578 proteinaceous extracellular matrix
1.39 5.50e-06 GO:0044421 extracellular region part
1.33 7.29e-03 GO:0005615 extracellular space
1.29 1.31e-07 GO:0005576 extracellular region
1.27 3.96e-03 GO:0031226 intrinsic to plasma membrane
1.26 8.82e-03 GO:0005887 integral to plasma membrane
1.23 8.71e-05 GO:0044459 plasma membrane part
1.16 3.34e-05 GO:0071944 cell periphery
1.16 7.08e-05 GO:0005886 plasma membrane
1.07 4.82e-02 GO:0016020 membrane

Gene overrepresentation in function category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
3.51 1.21e-03 GO:0005520 insulin-like growth factor binding
2.27 1.70e-05 GO:0019838 growth factor binding
1.34 4.59e-02 GO:0005509 calcium ion binding