Motif ID: MZF1.p2

Z-value: 3.296


Transcription factors associated with MZF1.p2:

Gene SymbolEntrez IDGene Name
MZF1 7593 myeloid zinc finger 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MZF1chr19_-_637765470.421.0e-01Click!


Activity profile for motif MZF1.p2.

activity profile for motif MZF1.p2


Sorted Z-values histogram for motif MZF1.p2

Sorted Z-values for motif MZF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MZF1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_+_22513043 16.382 NM_001013842
NM_001198827
NM_173686
 C8orf58


chromosome 8 open reading frame 58


chr9_+_108665168 8.509 NM_021224
 ZNF462
zinc finger protein 462
chr13_+_113574925 8.068 NM_001143945
 GAS6
growth arrest-specific 6
chrX_-_1291526 6.828 NM_001012288
NM_022148
 CRLF2

cytokine receptor-like factor 2

chr2_-_216944911 5.770 NM_020814
 MARCH4
membrane-associated ring finger (C3HC4) 4
chr1_-_72521079 5.664


chr11_-_127897098 5.657 ETS1
v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)
chr21_+_46226072 5.539 NM_001848
 COL6A1
collagen, type VI, alpha 1
chr11_-_127897271 5.272 NM_001162422
NM_005238
 ETS1

v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)

chr2_-_161058120 5.239 RBMS1
RNA binding motif, single stranded interacting protein 1
chr2_-_161058550 4.990 NM_002897
NM_016836
 RBMS1

RNA binding motif, single stranded interacting protein 1

chr7_-_27120015 4.794 HOXA3
homeobox A3
chr5_+_17270781 4.756 BASP1
brain abundant, membrane attached signal protein 1
chr22_-_28972683 4.516 NM_002309
 LIF
leukemia inhibitory factor (cholinergic differentiation factor)
chr12_+_64504835 4.442 HMGA2
high mobility group AT-hook 2
chr3_+_189354167 4.385 NM_001167672
 LPP
LIM domain containing preferred translocation partner in lipoma
chr3_-_189354510 4.283 LOC339929
hypothetical LOC339929
chr20_+_17498507 4.221 NM_001011546
NM_006870
 DSTN

destrin (actin depolymerizing factor)

chr6_-_10523203 4.198 TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr19_-_36531958 4.023 NM_020856
 TSHZ3
teashirt zinc finger homeobox 3

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 140 entries
enrichment   p-value GO term description
2.26 7.55e-03 GO:0061035 regulation of cartilage development
1.70 1.15e-02 GO:0030326 embryonic limb morphogenesis
1.70 1.15e-02 GO:0035113 embryonic appendage morphogenesis
1.67 3.93e-03 GO:0072001 renal system development
1.65 1.20e-02 GO:0001822 kidney development
1.61 1.05e-03 GO:0001655 urogenital system development
1.57 1.49e-02 GO:0060537 muscle tissue development
1.57 3.71e-02 GO:0014706 striated muscle tissue development
1.50 3.32e-02 GO:0009952 anterior/posterior pattern formation
1.48 1.48e-03 GO:0051129 negative regulation of cellular component organization
1.47 2.42e-09 GO:0000904 cell morphogenesis involved in differentiation
1.46 1.36e-03 GO:0030036 actin cytoskeleton organization
1.46 1.31e-02 GO:0001701 in utero embryonic development
1.45 2.79e-07 GO:0048667 cell morphogenesis involved in neuron differentiation
1.44 6.58e-08 GO:0031175 neuron projection development
1.44 2.11e-06 GO:0007409 axonogenesis
1.44 1.44e-03 GO:0010608 posttranscriptional regulation of gene expression
1.43 1.03e-06 GO:0048812 neuron projection morphogenesis
1.43 4.20e-03 GO:0045596 negative regulation of cell differentiation
1.43 2.27e-02 GO:0048011 nerve growth factor receptor signaling pathway

Gene overrepresentation in compartment category:

Showing 1 to 20 of 25 entries
enrichment   p-value GO term description
1.95 1.20e-02 GO:0008287 protein serine/threonine phosphatase complex
1.73 1.55e-04 GO:0005925 focal adhesion
1.72 7.08e-05 GO:0030055 cell-substrate junction
1.70 2.25e-04 GO:0005924 cell-substrate adherens junction
1.55 8.77e-04 GO:0005912 adherens junction
1.50 1.97e-03 GO:0070161 anchoring junction
1.49 4.27e-05 GO:0016323 basolateral plasma membrane
1.41 1.81e-02 GO:0030135 coated vesicle
1.29 2.60e-04 GO:0030054 cell junction
1.17 4.64e-06 GO:0005829 cytosol
1.13 1.53e-02 GO:0031981 nuclear lumen
1.11 4.13e-02 GO:0043233 organelle lumen
1.09 6.54e-11 GO:0005737 cytoplasm
1.09 7.46e-06 GO:0005634 nucleus
1.08 3.67e-04 GO:0044444 cytoplasmic part
1.07 5.71e-07 GO:0043227 membrane-bounded organelle
1.07 6.75e-07 GO:0043231 intracellular membrane-bounded organelle
1.07 1.31e-02 GO:0044446 intracellular organelle part
1.07 2.32e-02 GO:0044422 organelle part
1.06 2.32e-11 GO:0044424 intracellular part

Gene overrepresentation in function category:

Showing 1 to 11 of 11 entries
enrichment   p-value GO term description
1.35 6.32e-08 GO:0043565 sequence-specific DNA binding
1.34 2.46e-02 GO:0008134 transcription factor binding
1.33 2.44e-02 GO:0003779 actin binding
1.28 4.86e-07 GO:0001071 nucleic acid binding transcription factor activity
1.28 4.86e-07 GO:0003700 sequence-specific DNA binding transcription factor activity
1.28 3.19e-03 GO:0008092 cytoskeletal protein binding
1.26 4.13e-06 GO:0030528 transcription regulator activity
1.23 4.43e-02 GO:0004672 protein kinase activity
1.20 1.25e-02 GO:0030234 enzyme regulator activity
1.11 1.46e-15 GO:0005515 protein binding
1.05 2.22e-09 GO:0005488 binding