Motif ID: MZF1.p2

Z-value: 3.296


Transcription factors associated with MZF1.p2:

Gene SymbolEntrez IDGene Name
MZF1 7593 myeloid zinc finger 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MZF1chr19_-_637765470.421.0e-01Click!


Activity profile for motif MZF1.p2.

activity profile for motif MZF1.p2


Sorted Z-values histogram for motif MZF1.p2

Sorted Z-values for motif MZF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MZF1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_+_22513043 16.382 NM_001013842
NM_001198827
NM_173686
C8orf58


chromosome 8 open reading frame 58


chr9_+_108665168 8.509 NM_021224
ZNF462
zinc finger protein 462
chr13_+_113574925 8.068 NM_001143945
GAS6
growth arrest-specific 6
chrX_-_1291526 6.828 NM_001012288
NM_022148
CRLF2

cytokine receptor-like factor 2

chr2_-_216944911 5.770 NM_020814
MARCH4
membrane-associated ring finger (C3HC4) 4
chr1_-_72521079 5.664


chr11_-_127897098 5.657 ETS1
v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)
chr21_+_46226072 5.539 NM_001848
COL6A1
collagen, type VI, alpha 1
chr11_-_127897271 5.272 NM_001162422
NM_005238
ETS1

v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)

chr2_-_161058120 5.239 RBMS1
RNA binding motif, single stranded interacting protein 1
chr2_-_161058550 4.990 NM_002897
NM_016836
RBMS1

RNA binding motif, single stranded interacting protein 1

chr7_-_27120015 4.794 HOXA3
homeobox A3
chr5_+_17270781 4.756 BASP1
brain abundant, membrane attached signal protein 1
chr22_-_28972683 4.516 NM_002309
LIF
leukemia inhibitory factor (cholinergic differentiation factor)
chr12_+_64504835 4.442 HMGA2
high mobility group AT-hook 2
chr3_+_189354167 4.385 NM_001167672
LPP
LIM domain containing preferred translocation partner in lipoma
chr3_-_189354510 4.283 LOC339929
hypothetical LOC339929
chr20_+_17498507 4.221 NM_001011546
NM_006870
DSTN

destrin (actin depolymerizing factor)

chr6_-_10523203 4.198 TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr19_-_36531958 4.023 NM_020856
TSHZ3
teashirt zinc finger homeobox 3
chrX_+_73557809 3.978 NM_006517
SLC16A2
solute carrier family 16, member 2 (monocarboxylic acid transporter 8)
chr2_+_69093641 3.726 NM_018153
NM_032208
NM_053034
ANTXR1


anthrax toxin receptor 1


chr3_-_121652183 3.695 NM_007085
FSTL1
follistatin-like 1
chr7_+_55054152 3.695 NM_005228
NM_201282
NM_201283
NM_201284
EGFR



epidermal growth factor receptor



chr17_+_30594192 3.660 NM_144975
SLFN5
schlafen family member 5
chr6_-_10523424 3.648 NM_003220
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr10_+_73393998 3.550 NM_004273
CHST3
carbohydrate (chondroitin 6) sulfotransferase 3
chr1_-_72520735 3.507 NM_173808
NEGR1
neuronal growth regulator 1
chr12_-_51912101 3.477 NM_000966
RARG
retinoic acid receptor, gamma
chr10_-_126839000 3.473 CTBP2
C-terminal binding protein 2
chr1_-_223907283 3.449 NM_001008493
NM_018212
ENAH

enabled homolog (Drosophila)

chr10_-_126839056 3.447 NM_001329
CTBP2
C-terminal binding protein 2
chr5_-_73972055 3.411 ENC1
ectodermal-neural cortex 1 (with BTB-like domain)
chr19_-_51168396 3.380 NM_002516
NOVA2
neuro-oncological ventral antigen 2
chr19_-_1966628 3.377 NM_017797
BTBD2
BTB (POZ) domain containing 2
chr6_-_75972473 3.355 COL12A1
collagen, type XII, alpha 1
chr5_-_9599157 3.345 NM_003966
SEMA5A
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr21_+_42946719 3.305 NM_001001567
NM_001001568
NM_001001569
NM_001001570
NM_001001571
NM_001001572
NM_001001573
NM_001001574
NM_001001575
NM_001001576
NM_001001577
NM_001001578
NM_001001579
NM_001001580
NM_001001581
NM_001001582
NM_001001583
NM_001001584
NM_001001585
NM_002606
PDE9A



















phosphodiesterase 9A



















chr18_+_54682261 3.303 ZNF532
zinc finger protein 532
chr16_-_71650034 3.288 NM_001164766
ZFHX3
zinc finger homeobox 3
chr4_-_140696740 3.278 NM_030648
SETD7
SET domain containing (lysine methyltransferase) 7
chr1_+_198975227 3.270 NM_203459
CAMSAP1L1
calmodulin regulated spectrin-associated protein 1-like 1
chr4_+_81406765 3.266 NM_004464
NM_033143
FGF5

fibroblast growth factor 5

chr21_-_27261276 3.261 NM_007038
ADAMTS5
ADAM metallopeptidase with thrombospondin type 1 motif, 5
chr1_+_15957832 3.233 NM_017556
FBLIM1
filamin binding LIM protein 1
chr20_-_61574259 3.231 NM_004518
NM_172106
NM_172107
NM_172108
NM_172109
KCNQ2




potassium voltage-gated channel, KQT-like subfamily, member 2




chr8_+_95722448 3.209 ESRP1
epithelial splicing regulatory protein 1
chr1_+_181259317 3.207


chr1_+_181258952 3.203 NM_002293
LAMC1
laminin, gamma 1 (formerly LAMB2)
chr6_-_42527760 3.142 NM_033502
TRERF1
transcriptional regulating factor 1
chr6_+_17501589 3.083 NM_006366
CAP2
CAP, adenylate cyclase-associated protein, 2 (yeast)
chr4_-_158111916 3.080 PDGFC
platelet derived growth factor C
chr18_-_55515623 3.077 NM_133459
CCBE1
collagen and calcium binding EGF domains 1
chr12_+_55201854 3.051 NM_002898
RBMS2
RNA binding motif, single stranded interacting protein 2
chr9_+_138341752 3.047 NM_001145638
NM_015597
GPSM1

G-protein signaling modulator 1

chr18_-_55515552 3.040 CCBE1
collagen and calcium binding EGF domains 1
chr6_-_10520592 3.016 NM_001032280
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr13_+_72531098 2.948 NM_001730
KLF5
Kruppel-like factor 5 (intestinal)
chr11_+_66499323 2.910 NM_001136485
C11orf86
chromosome 11 open reading frame 86
chr4_-_158111995 2.905 NM_016205
PDGFC
platelet derived growth factor C
chr22_-_34566276 2.887 RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr1_-_85816520 2.879 NM_001134445
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr17_+_58058783 2.869 MRC2
mannose receptor, C type 2
chr10_-_105604942 2.847 NM_014631
SH3PXD2A
SH3 and PX domains 2A
chr6_-_72187168 2.847 C6orf155
chromosome 6 open reading frame 155
chr17_-_24068759 2.789 NM_001144942
NM_031934
RAB34

RAB34, member RAS oncogene family

chr6_-_10520264 2.777 TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr4_-_11039600 2.758 NM_005114
HS3ST1
heparan sulfate (glucosamine) 3-O-sulfotransferase 1
chr8_+_30361485 2.738 NM_001008710
NM_001008711
NM_001008712
NM_006867
RBPMS



RNA binding protein with multiple splicing



chr19_-_242335 2.709 NM_003712
NM_177526
PPAP2C

phosphatidic acid phosphatase type 2C

chr17_+_18255753 2.694 FLJ35934
FLJ35934
chr5_-_92942680 2.681 FLJ42709
hypothetical LOC441094
chr13_-_39075200 2.666 LHFP
lipoma HMGIC fusion partner
chr19_-_242168 2.656 NM_177543
PPAP2C
phosphatidic acid phosphatase type 2C
chr4_-_102487506 2.642 PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chr9_-_14304036 2.592 NM_001190737
NM_005596
NFIB

nuclear factor I/B

chr11_+_35596310 2.586 NM_014344
FJX1
four jointed box 1 (Drosophila)
chr8_+_95722575 2.559 ESRP1
epithelial splicing regulatory protein 1
chr3_+_23219707 2.556 NM_152653
UBE2E2
ubiquitin-conjugating enzyme E2E 2 (UBC4/5 homolog, yeast)
chr2_-_207738858 2.501 NM_003709
KLF7
Kruppel-like factor 7 (ubiquitous)
chrX_+_100361588 2.500 NM_001171184
NM_001939
DRP2

dystrophin related protein 2

chr9_+_135880363 2.494 NCRNA00094
non-protein coding RNA 94
chr11_-_10272256 2.486 NM_030962
SBF2
SET binding factor 2
chr17_-_24069299 2.475 NM_001142624
NM_001142625
NM_001144943
RAB34


RAB34, member RAS oncogene family


chr1_-_212791597 2.470 NM_005401
PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr13_-_43259032 2.438 NM_017993
ENOX1
ecto-NOX disulfide-thiol exchanger 1
chr12_-_105056577 2.431 NUAK1
NUAK family, SNF1-like kinase, 1
chr4_-_86106567 2.428 NM_014991
WDFY3
WD repeat and FYVE domain containing 3
chr12_-_105165805 2.414 NM_006825
CKAP4
cytoskeleton-associated protein 4
chr6_+_116798791 2.412 NM_013352
DSE
dermatan sulfate epimerase
chr12_+_74071145 2.405 NM_152436
GLIPR1L2
GLI pathogenesis-related 1 like 2
chr9_+_77695334 2.394 NM_001190482
NM_006200
PCSK5

proprotein convertase subtilisin/kexin type 5

chr7_+_55054416 2.369 EGFR
epidermal growth factor receptor
chr8_+_95722516 2.363 NM_001034915
NM_001122825
NM_001122826
NM_001122827
NM_017697
ESRP1




epithelial splicing regulatory protein 1




chr22_-_34566210 2.355 RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr12_+_63958949 2.346 NM_001193461
MSRB3
methionine sulfoxide reductase B3
chr16_+_49333513 2.344 NM_001042412
CYLD
cylindromatosis (turban tumor syndrome)
chr18_+_44319365 2.333 NM_001142397
NM_014772
CTIF

CBP80/20-dependent translation initiation factor

chr22_-_34566367 2.327 NM_001031695
NM_001082576
NM_001082577
NM_014309
RBFOX2



RNA binding protein, fox-1 homolog (C. elegans) 2



chr1_+_162795328 2.313 NM_002585
PBX1
pre-B-cell leukemia homeobox 1
chr7_+_27102508 2.308


chr1_+_78126787 2.274 NM_001172309
NM_144573
NEXN

nexilin (F actin binding protein)

chr1_+_199884152 2.257 NAV1
neuron navigator 1
chr7_-_27136876 2.237 NM_002141
HOXA4
homeobox A4
chr2_+_36436316 2.222 CRIM1
cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr4_+_183302105 2.214 ODZ3
odz, odd Oz/ten-m homolog 3 (Drosophila)
chr12_+_63958689 2.213 NM_001031679
NM_001193460
NM_198080
MSRB3


methionine sulfoxide reductase B3


chr4_-_102487649 2.212 NM_000944
NM_001130691
NM_001130692
PPP3CA


protein phosphatase 3, catalytic subunit, alpha isozyme


chr11_+_86189138 2.211 NM_007173
PRSS23
protease, serine, 23
chr11_-_27677755 2.211 NM_170734
BDNF
brain-derived neurotrophic factor
chr10_-_126839546 2.194 NM_001083914
CTBP2
C-terminal binding protein 2
chr9_-_4289574 2.186 GLIS3
GLIS family zinc finger 3
chr12_+_13240987 2.155 EMP1
epithelial membrane protein 1
chr8_+_37672427 2.154 NM_025069
ZNF703
zinc finger protein 703
chr12_+_74071116 2.152 GLIPR1L2
GLI pathogenesis-related 1 like 2
chr6_-_16869579 2.120 NM_000332
NM_001128164
ATXN1

ataxin 1

chr9_+_33807213 2.117 UBE2R2
ubiquitin-conjugating enzyme E2R 2
chr9_-_14303943 2.105 NFIB
nuclear factor I/B
chr9_-_14303899 2.101 NFIB
nuclear factor I/B
chr5_+_17270474 2.087 NM_006317
BASP1
brain abundant, membrane attached signal protein 1
chr19_+_43572679 2.080 NM_001039616
NM_001042522
SPRED3

sprouty-related, EVH1 domain containing 3

chrX_+_154650590 2.033 NM_005840
SPRY3
sprouty homolog 3 (Drosophila)
chr7_+_28692122 2.021 NM_001011666
CREB5
cAMP responsive element binding protein 5
chr3_-_55496370 2.017 NM_003392
WNT5A
wingless-type MMTV integration site family, member 5A
chr18_+_18003401 2.003 NM_005257
GATA6
GATA binding protein 6
chr4_-_158111504 1.993 PDGFC
platelet derived growth factor C
chr4_+_30330963 1.985 NM_001173523
NM_002589
NM_032456
NM_032457
PCDH7



protocadherin 7



chr2_+_28469864 1.979 FOSL2
FOS-like antigen 2
chr2_-_160972606 1.975 RBMS1
RNA binding motif, single stranded interacting protein 1
chr4_-_102487356 1.953 PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chr19_+_46416975 1.949 AXL
AXL receptor tyrosine kinase
chr4_-_115120251 1.947 NM_024590
ARSJ
arylsulfatase family, member J
chr17_+_2443983 1.947 PAFAH1B1
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
chr10_-_35143900 1.945 NM_001184785
NM_001184786
NM_001184787
NM_001184788
NM_001184789
NM_001184790
NM_001184791
NM_001184792
NM_001184793
NM_001184794
NM_019619
PARD3










par-3 partitioning defective 3 homolog (C. elegans)










chr16_-_17472238 1.943 NM_022166
XYLT1
xylosyltransferase I
chr6_-_35804337 1.941 NM_001145775
FKBP5
FK506 binding protein 5
chr15_+_97010219 1.937 NM_000875
IGF1R
insulin-like growth factor 1 receptor
chr14_+_85069217 1.926


chr1_-_143750988 1.925 NM_001198832
PDE4DIP
phosphodiesterase 4D interacting protein
chr16_-_63713485 1.886 CDH11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr1_+_199884072 1.884 NM_020443
NAV1
neuron navigator 1
chr20_+_1823534 1.883 SIRPA
signal-regulatory protein alpha
chr7_+_24579239 1.882 NM_016447
MPP6
membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
chr16_-_63713466 1.877 CDH11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr9_+_111850770 1.876 AKAP2
A kinase (PRKA) anchor protein 2
chr17_+_52026058 1.876 NM_005450
NOG
noggin
chr16_+_49333461 1.870 NM_001042355
NM_015247
CYLD

cylindromatosis (turban tumor syndrome)

chr9_+_111850698 1.863 NM_001004065
NM_001198656
AKAP2

A kinase (PRKA) anchor protein 2

chr19_-_56196611 1.847 NM_007196
NM_144505
NM_144506
NM_144507
KLK8



kallikrein-related peptidase 8



chr12_+_51777715 1.844 IGFBP6
insulin-like growth factor binding protein 6
chr20_-_10602429 1.843 NM_000214
JAG1
jagged 1
chr2_-_56004366 1.838 NM_001039348
NM_001039349
EFEMP1

EGF containing fibulin-like extracellular matrix protein 1

chr15_+_88345612 1.826 NM_198526
ZNF710
zinc finger protein 710
chr12_-_6313219 1.823 TNFRSF1A
tumor necrosis factor receptor superfamily, member 1A
chr1_-_146398501 1.816 LOC100286793
FLJ39739
hypothetical LOC100286793
hypothetical FLJ39739
chr11_+_69165119 1.799 CCND1
cyclin D1
chr19_+_60691671 1.795 NM_001144950
NM_001195267
SSC5D

scavenger receptor cysteine rich domain containing (5 domains)

chr16_-_63713382 1.780 NM_001797
CDH11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr6_-_30763057 1.774 NM_001134870
KIAA1949
KIAA1949
chr9_-_109291866 1.774 NM_004235
KLF4
Kruppel-like factor 4 (gut)
chr14_-_88090641 1.771 NM_007039
PTPN21
protein tyrosine phosphatase, non-receptor type 21
chr2_+_85834111 1.769 NM_032827
ATOH8
atonal homolog 8 (Drosophila)
chr17_+_2443652 1.749 NM_000430
PAFAH1B1
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
chr11_-_56846246 1.748 TNKS1BP1
tankyrase 1 binding protein 1, 182kDa
chr19_+_46416938 1.747 NM_001699
NM_021913
AXL

AXL receptor tyrosine kinase

chr17_-_73867748 1.731 NM_003955
SOCS3
suppressor of cytokine signaling 3
chr12_+_52653176 1.731 NM_014212
HOXC11
homeobox C11
chr3_-_41978464 1.728 NM_017886
ULK4
unc-51-like kinase 4 (C. elegans)
chr2_+_36436873 1.727 NM_016441
CRIM1
cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr8_-_9045548 1.723 NM_024607
PPP1R3B
protein phosphatase 1, regulatory (inhibitor) subunit 3B
chr1_+_144183811 1.715 ANKRD34A
ankyrin repeat domain 34A
chr10_+_114699953 1.714 NM_001146274
NM_001146283
NM_001146284
NM_001146285
NM_001146286
NM_001198525
NM_001198526
NM_001198527
NM_001198528
NM_001198529
NM_001198530
NM_001198531
NM_030756
TCF7L2












transcription factor 7-like 2 (T-cell specific, HMG-box)












chr5_+_49998677 1.714 PARP8
poly (ADP-ribose) polymerase family, member 8
chr9_-_4290028 1.712 NM_001042413
GLIS3
GLIS family zinc finger 3
chr8_-_11096257 1.710 NM_173683
XKR6
XK, Kell blood group complex subunit-related family, member 6
chr5_-_77980097 1.698 NM_005779
LHFPL2
lipoma HMGIC fusion partner-like 2
chr20_+_1823825 1.691 NM_001040023
SIRPA
signal-regulatory protein alpha
chr19_+_46416971 1.684 AXL
AXL receptor tyrosine kinase
chr12_-_47468985 1.675 NM_020983
ADCY6
adenylate cyclase 6
chr12_+_8741746 1.667 NM_020734
RIMKLB
ribosomal modification protein rimK-like family member B
chr11_+_36354110 1.667 NM_001160168
NM_024841
PRR5L

proline rich 5 like

chr7_+_28415495 1.666 LOC401317
hypothetical LOC401317
chr12_+_51777684 1.663 NM_002178
IGFBP6
insulin-like growth factor binding protein 6
chr4_+_89147821 1.659 NM_000297
PKD2
polycystic kidney disease 2 (autosomal dominant)
chr9_+_117955890 1.655 NM_002581
PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chr12_-_131816604 1.653 ANKLE2
ankyrin repeat and LEM domain containing 2
chr6_-_75972286 1.653 NM_004370
NM_080645
COL12A1

collagen, type XII, alpha 1

chr11_+_69165065 1.645 CCND1
cyclin D1
chr19_+_12996745 1.634 NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr16_-_3225360 1.633 NM_001145448
NM_198088
NM_001145446
NM_198087
ZNF200



zinc finger protein 200



chr4_+_87734489 1.631 NM_006264
NM_080683
NM_080684
NM_080685
PTPN13



protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)



chr11_+_109468734 1.625 ZC3H12C
zinc finger CCCH-type containing 12C
chr9_-_109291575 1.620 KLF4
Kruppel-like factor 4 (gut)
chr6_-_30762957 1.617 KIAA1949
KIAA1949
chr20_+_1824006 1.607 SIRPA
signal-regulatory protein alpha
chr11_+_69165018 1.602 NM_053056
CCND1
cyclin D1
chr12_+_13240983 1.601 EMP1
epithelial membrane protein 1
chr7_+_114349376 1.600 NM_001166345
NM_001166346
NM_199072
MDFIC


MyoD family inhibitor domain containing


chr7_-_78920806 1.599 NM_012301
MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr18_+_19848749 1.596 TTC39C
tetratricopeptide repeat domain 39C

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.08 3.23e-19 GO:0009987 cellular process
1.12 8.70e-19 GO:0065007 biological regulation
1.13 9.57e-17 GO:0050794 regulation of cellular process
1.12 2.19e-16 GO:0050789 regulation of biological process
1.33 4.31e-16 GO:0007399 nervous system development
1.22 1.76e-14 GO:0048731 system development
1.31 7.40e-14 GO:0009653 anatomical structure morphogenesis
1.19 7.42e-14 GO:0007275 multicellular organismal development
1.18 8.03e-14 GO:0032502 developmental process
1.26 1.88e-13 GO:0030154 cell differentiation
1.20 3.35e-13 GO:0048856 anatomical structure development
1.39 5.36e-13 GO:0022008 neurogenesis
1.25 7.34e-13 GO:0048869 cellular developmental process
1.23 1.24e-12 GO:0048522 positive regulation of cellular process
1.39 1.45e-11 GO:0048699 generation of neurons
1.37 1.54e-11 GO:0048468 cell development
1.20 2.13e-11 GO:0048518 positive regulation of biological process
1.40 1.19e-09 GO:0030182 neuron differentiation
1.47 2.42e-09 GO:0000904 cell morphogenesis involved in differentiation
1.15 4.01e-09 GO:0023052 signaling
1.41 6.51e-09 GO:0032989 cellular component morphogenesis
1.42 9.46e-09 GO:0048666 neuron development
1.35 1.98e-08 GO:0051128 regulation of cellular component organization
1.39 2.29e-08 GO:0007167 enzyme linked receptor protein signaling pathway
1.33 2.50e-08 GO:0050793 regulation of developmental process
1.44 6.58e-08 GO:0031175 neuron projection development
1.39 9.84e-08 GO:0000902 cell morphogenesis
1.15 1.92e-07 GO:0007165 signal transduction
1.36 2.45e-07 GO:0045595 regulation of cell differentiation
1.14 2.49e-07 GO:0031323 regulation of cellular metabolic process
1.34 2.67e-07 GO:2000026 regulation of multicellular organismal development
1.37 2.72e-07 GO:0030030 cell projection organization
1.45 2.79e-07 GO:0048667 cell morphogenesis involved in neuron differentiation
1.13 4.88e-07 GO:0051716 cellular response to stimulus
1.14 5.15e-07 GO:0080090 regulation of primary metabolic process
1.19 5.42e-07 GO:0048523 negative regulation of cellular process
1.18 7.82e-07 GO:0048519 negative regulation of biological process
1.43 1.03e-06 GO:0048812 neuron projection morphogenesis
1.26 1.09e-06 GO:0010604 positive regulation of macromolecule metabolic process
1.11 1.92e-06 GO:0043170 macromolecule metabolic process
1.33 2.06e-06 GO:0010557 positive regulation of macromolecule biosynthetic process
1.44 2.11e-06 GO:0007409 axonogenesis
1.34 2.56e-06 GO:0010628 positive regulation of gene expression
1.39 2.77e-06 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.21 2.84e-06 GO:0023051 regulation of signaling
1.14 4.23e-06 GO:0060255 regulation of macromolecule metabolic process
1.39 4.56e-06 GO:0048858 cell projection morphogenesis
1.23 5.32e-06 GO:0009966 regulation of signal transduction
1.34 5.75e-06 GO:0051254 positive regulation of RNA metabolic process
1.35 6.70e-06 GO:0045893 positive regulation of transcription, DNA-dependent
1.39 6.73e-06 GO:0032990 cell part morphogenesis
1.30 7.79e-06 GO:0031328 positive regulation of cellular biosynthetic process
1.19 7.90e-06 GO:0048513 organ development
1.12 9.70e-06 GO:0019222 regulation of metabolic process
1.31 1.03e-05 GO:0051173 positive regulation of nitrogen compound metabolic process
1.09 1.11e-05 GO:0044238 primary metabolic process
1.24 1.29e-05 GO:0031325 positive regulation of cellular metabolic process
1.31 1.35e-05 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.11 1.78e-05 GO:0044260 cellular macromolecule metabolic process
1.23 1.91e-05 GO:0051239 regulation of multicellular organismal process
1.19 2.02e-05 GO:0048583 regulation of response to stimulus
1.29 2.09e-05 GO:0009891 positive regulation of biosynthetic process
1.23 2.27e-05 GO:0009893 positive regulation of metabolic process
1.13 3.35e-05 GO:0016043 cellular component organization
1.16 3.93e-05 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.13 5.19e-05 GO:0071840 cellular component organization or biogenesis
1.15 5.47e-05 GO:0071842 cellular component organization at cellular level
1.15 6.28e-05 GO:0031326 regulation of cellular biosynthetic process
1.14 1.07e-04 GO:0009889 regulation of biosynthetic process
1.08 1.13e-04 GO:0008152 metabolic process
1.16 1.53e-04 GO:0065008 regulation of biological quality
1.25 2.30e-04 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.15 2.33e-04 GO:0010556 regulation of macromolecule biosynthetic process
1.14 2.77e-04 GO:0071841 cellular component organization or biogenesis at cellular level
1.14 4.20e-04 GO:0010468 regulation of gene expression
1.40 4.33e-04 GO:0043009 chordate embryonic development
1.38 6.37e-04 GO:0007264 small GTPase mediated signal transduction
1.39 6.42e-04 GO:0009792 embryo development ending in birth or egg hatching
1.08 8.44e-04 GO:0044237 cellular metabolic process
1.61 1.05e-03 GO:0001655 urogenital system development
1.28 1.18e-03 GO:0009790 embryo development
1.27 1.21e-03 GO:0006468 protein phosphorylation
1.30 1.24e-03 GO:0009887 organ morphogenesis
1.46 1.36e-03 GO:0030036 actin cytoskeleton organization
1.44 1.44e-03 GO:0010608 posttranscriptional regulation of gene expression
1.48 1.48e-03 GO:0051129 negative regulation of cellular component organization
1.24 1.83e-03 GO:0009888 tissue development
1.16 1.84e-03 GO:0007166 cell surface receptor linked signaling pathway
1.33 2.27e-03 GO:0072358 cardiovascular system development
1.33 2.27e-03 GO:0072359 circulatory system development
1.39 2.32e-03 GO:0007411 axon guidance
1.24 2.42e-03 GO:0008219 cell death
1.23 2.53e-03 GO:0032879 regulation of localization
1.24 2.76e-03 GO:0006351 transcription, DNA-dependent
1.33 3.90e-03 GO:0051094 positive regulation of developmental process
1.67 3.93e-03 GO:0072001 renal system development
1.13 4.00e-03 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.43 4.20e-03 GO:0045596 negative regulation of cell differentiation
1.23 4.35e-03 GO:0016265 death
1.11 4.58e-03 GO:0051179 localization
1.12 6.19e-03 GO:0051171 regulation of nitrogen compound metabolic process
1.27 7.26e-03 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.38 7.53e-03 GO:0001501 skeletal system development
2.26 7.55e-03 GO:0061035 regulation of cartilage development
1.23 7.66e-03 GO:0031324 negative regulation of cellular metabolic process
1.22 7.82e-03 GO:0042127 regulation of cell proliferation
1.39 9.23e-03 GO:0051130 positive regulation of cellular component organization
1.37 9.36e-03 GO:0045597 positive regulation of cell differentiation
1.21 9.55e-03 GO:0006793 phosphorus metabolic process
1.21 9.55e-03 GO:0006796 phosphate metabolic process
1.21 1.11e-02 GO:0009605 response to external stimulus
1.70 1.15e-02 GO:0030326 embryonic limb morphogenesis
1.70 1.15e-02 GO:0035113 embryonic appendage morphogenesis
1.65 1.20e-02 GO:0001822 kidney development
1.31 1.20e-02 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.13 1.23e-02 GO:0051252 regulation of RNA metabolic process
1.46 1.31e-02 GO:0001701 in utero embryonic development
1.57 1.49e-02 GO:0060537 muscle tissue development
1.25 1.55e-02 GO:0006915 apoptosis
1.18 1.63e-02 GO:0035556 intracellular signal transduction
1.11 1.66e-02 GO:0006807 nitrogen compound metabolic process
1.35 1.91e-02 GO:0007389 pattern specification process
1.21 1.96e-02 GO:0009892 negative regulation of metabolic process
1.21 2.09e-02 GO:0010605 negative regulation of macromolecule metabolic process
1.20 2.15e-02 GO:0032268 regulation of cellular protein metabolic process
1.43 2.27e-02 GO:0048011 nerve growth factor receptor signaling pathway
1.19 2.30e-02 GO:0051246 regulation of protein metabolic process
1.36 2.41e-02 GO:0051093 negative regulation of developmental process
1.25 2.56e-02 GO:0031327 negative regulation of cellular biosynthetic process
1.25 2.76e-02 GO:0010558 negative regulation of macromolecule biosynthetic process
1.11 2.93e-02 GO:0019538 protein metabolic process
1.24 3.19e-02 GO:0012501 programmed cell death
1.36 3.22e-02 GO:0060284 regulation of cell development
1.50 3.32e-02 GO:0009952 anterior/posterior pattern formation
1.20 3.50e-02 GO:0032774 RNA biosynthetic process
1.57 3.71e-02 GO:0014706 striated muscle tissue development
1.22 4.02e-02 GO:0016310 phosphorylation
1.38 4.41e-02 GO:0035295 tube development
1.25 4.54e-02 GO:0009725 response to hormone stimulus
1.14 4.92e-02 GO:0006464 protein modification process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.06 2.32e-11 GO:0044424 intracellular part
1.09 6.54e-11 GO:0005737 cytoplasm
1.06 3.70e-10 GO:0005622 intracellular
1.06 2.93e-07 GO:0043226 organelle
1.07 5.71e-07 GO:0043227 membrane-bounded organelle
1.06 5.87e-07 GO:0043229 intracellular organelle
1.07 6.75e-07 GO:0043231 intracellular membrane-bounded organelle
1.17 4.64e-06 GO:0005829 cytosol
1.09 7.46e-06 GO:0005634 nucleus
1.49 4.27e-05 GO:0016323 basolateral plasma membrane
1.72 7.08e-05 GO:0030055 cell-substrate junction
1.73 1.55e-04 GO:0005925 focal adhesion
1.70 2.25e-04 GO:0005924 cell-substrate adherens junction
1.29 2.60e-04 GO:0030054 cell junction
1.08 3.67e-04 GO:0044444 cytoplasmic part
1.02 4.95e-04 GO:0005623 cell
1.02 5.82e-04 GO:0044464 cell part
1.55 8.77e-04 GO:0005912 adherens junction
1.50 1.97e-03 GO:0070161 anchoring junction
1.95 1.20e-02 GO:0008287 protein serine/threonine phosphatase complex
1.07 1.31e-02 GO:0044446 intracellular organelle part
1.13 1.53e-02 GO:0031981 nuclear lumen
1.41 1.81e-02 GO:0030135 coated vesicle
1.07 2.32e-02 GO:0044422 organelle part
1.11 4.13e-02 GO:0043233 organelle lumen

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.11 1.46e-15 GO:0005515 protein binding
1.05 2.22e-09 GO:0005488 binding
1.35 6.32e-08 GO:0043565 sequence-specific DNA binding
1.28 4.86e-07 GO:0001071 nucleic acid binding transcription factor activity
1.28 4.86e-07 GO:0003700 sequence-specific DNA binding transcription factor activity
1.26 4.13e-06 GO:0030528 transcription regulator activity
1.28 3.19e-03 GO:0008092 cytoskeletal protein binding
1.20 1.25e-02 GO:0030234 enzyme regulator activity
1.33 2.44e-02 GO:0003779 actin binding
1.34 2.46e-02 GO:0008134 transcription factor binding
1.23 4.43e-02 GO:0004672 protein kinase activity