Motif ID: NFE2.p2

Z-value: 1.467


Transcription factors associated with NFE2.p2:

Gene SymbolEntrez IDGene Name
NFE2 4778 nuclear factor (erythroid-derived 2), 45kDa

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NFE2chr12_-_529809140.283.0e-01Click!


Activity profile for motif NFE2.p2.

activity profile for motif NFE2.p2


Sorted Z-values histogram for motif NFE2.p2

Sorted Z-values for motif NFE2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFE2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_-_141041982 4.267 NM_022481
 ARAP3
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr5_-_141041933 3.544 ARAP3
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr10_-_6059460 3.092 NM_002189
NM_172200
 IL15RA

interleukin 15 receptor, alpha

chr15_+_38849450 2.890 NM_001130448
 C15orf62
chromosome 15 open reading frame 62
chr11_+_118463906 2.525 NM_001024382
 HMBS
hydroxymethylbilane synthase
chr12_-_15005761 2.459 NM_001175
 ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr7_-_86526880 2.443 NM_001142749
 KIAA1324L
KIAA1324-like
chrX_-_100527799 2.373 NM_000061
 BTK
Bruton agammaglobulinemia tyrosine kinase
chr12_-_51629874 2.261 KRT8
keratin 8
chr1_-_156923111 2.069 NM_003126
 SPTA1
spectrin, alpha, erythrocytic 1 (elliptocytosis 2)
chr11_+_20342262 2.028 NM_001098523
 HTATIP2
HIV-1 Tat interactive protein 2, 30kDa
chr16_-_1369613 1.980 NM_001193389
NM_023076
 UNKL

unkempt homolog (Drosophila)-like

chr6_+_34314545 1.978 NM_145905
 HMGA1
high mobility group AT-hook 1
chr18_+_54039818 1.966 NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr3_-_197549640 1.923 NM_138461
 TM4SF19
transmembrane 4 L six family member 19
chr3_-_197549588 1.868 TM4SF19
transmembrane 4 L six family member 19
chr6_-_28429950 1.825 NM_145909
 ZNF323
zinc finger protein 323
chr6_-_84197573 1.784 NM_002395
 ME1
malic enzyme 1, NADP(+)-dependent, cytosolic
chr1_-_93030538 1.761 NM_005665
 EVI5
ecotropic viral integration site 5
chrX_+_9391314 1.759 NM_001139466
NM_001139467
NM_001139468
 TBL1X


transducin (beta)-like 1X-linked



Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
4.46 1.02e-02 GO:0006521 regulation of cellular amino acid metabolic process
3.98 1.87e-02 GO:0033238 regulation of cellular amine metabolic process
1.64 7.65e-03 GO:0051246 regulation of protein metabolic process
1.60 4.32e-02 GO:0042981 regulation of apoptosis
1.56 4.26e-02 GO:0050790 regulation of catalytic activity
1.33 4.82e-03 GO:0007165 signal transduction
1.30 8.04e-03 GO:0023052 signaling
1.28 1.62e-02 GO:0051716 cellular response to stimulus

Gene overrepresentation in compartment category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
6.37 2.18e-02 GO:0005839 proteasome core complex
6.06 3.11e-02 GO:0001533 cornified envelope
4.91 1.12e-05 GO:0000502 proteasome complex

Gene overrepresentation in function category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
6.06 4.80e-02 GO:0004298 threonine-type endopeptidase activity
6.06 4.80e-02 GO:0070003 threonine-type peptidase activity
3.75 8.91e-03 GO:0004197 cysteine-type endopeptidase activity