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• Activity deltas table
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Motif ID: NFE2.p2

Z-value: 1.467

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr5_-_141041982	4.267	NM_022481	ARAP3	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr5_-_141041933	3.544		ARAP3	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr10_-_6059460	3.092	NM_002189 NM_172200	IL15RA	interleukin 15 receptor, alpha
chr15_+_38849450	2.890	NM_001130448	C15orf62	chromosome 15 open reading frame 62
chr11_+_118463906	2.525	NM_001024382	HMBS	hydroxymethylbilane synthase
chr12_-_15005761	2.459	NM_001175	ARHGDIB	Rho GDP dissociation inhibitor (GDI) beta
chr7_-_86526880	2.443	NM_001142749	KIAA1324L	KIAA1324-like
chrX_-_100527799	2.373	NM_000061	BTK	Bruton agammaglobulinemia tyrosine kinase
chr12_-_51629874	2.261		KRT8	keratin 8
chr1_-_156923111	2.069	NM_003126	SPTA1	spectrin, alpha, erythrocytic 1 (elliptocytosis 2)
chr11_+_20342262	2.028	NM_001098523	HTATIP2	HIV-1 Tat interactive protein 2, 30kDa
chr16_-_1369613	1.980	NM_001193389 NM_023076	UNKL	unkempt homolog (Drosophila)-like
chr6_+_34314545	1.978	NM_145905	HMGA1	high mobility group AT-hook 1
chr18_+_54039818	1.966		NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like
chr3_-_197549640	1.923	NM_138461	TM4SF19	transmembrane 4 L six family member 19
chr3_-_197549588	1.868		TM4SF19	transmembrane 4 L six family member 19
chr6_-_28429950	1.825	NM_145909	ZNF323	zinc finger protein 323
chr6_-_84197573	1.784	NM_002395	ME1	malic enzyme 1, NADP(+)-dependent, cytosolic
chr1_-_93030538	1.761	NM_005665	EVI5	ecotropic viral integration site 5
chrX_+_9391314	1.759	NM_001139466 NM_001139467 NM_001139468	TBL1X	transducin (beta)-like 1X-linked
chr6_+_106653429	1.707	NM_182907	PRDM1	PR domain containing 1, with ZNF domain
chr11_+_20341900	1.704	NM_001098522	HTATIP2	HIV-1 Tat interactive protein 2, 30kDa
chrX_-_154216929	1.692	NM_001289	CLIC2	chloride intracellular channel 2
chr10_+_70745615	1.668	NM_033496	HK1	hexokinase 1
chr11_+_384199	1.644	NM_007183	PKP3	plakophilin 3
chr12_-_68369322	1.643	NM_152439	BEST3	bestrophin 3
chr6_-_84197477	1.636		ME1	malic enzyme 1, NADP(+)-dependent, cytosolic
chr4_-_38710376	1.630	NM_024943	TMEM156	transmembrane protein 156
chr6_-_84197463	1.612		ME1	malic enzyme 1, NADP(+)-dependent, cytosolic
chr18_+_54039779	1.607		NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like
chr11_+_20341835	1.605	NM_001098520	HTATIP2	HIV-1 Tat interactive protein 2, 30kDa
chr6_-_84197370	1.601		ME1	malic enzyme 1, NADP(+)-dependent, cytosolic
chr11_+_20341806	1.585	NM_006410 NM_001098521	HTATIP2	HIV-1 Tat interactive protein 2, 30kDa
chr1_-_159257567	1.573		F11R	F11 receptor
chrX_-_15421279	1.571	NM_001018109 NM_003662	PIR	pirin (iron-binding nuclear protein)
chr1_+_153232685	1.512	NM_018655	LENEP	lens epithelial protein
chr18_+_54039730	1.492	NM_001144966	NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like
chr19_-_54350457	1.456	NM_002152	HRC	histidine rich calcium binding protein
chr19_-_53935648	1.450	NM_017805	RASIP1	Ras interacting protein 1
chr22_-_25343959	1.427	NM_001887	CRYBB1	crystallin, beta B1
chr4_+_74825138	1.405	NM_000584	IL8	interleukin 8
chr1_+_76024466	1.401	NM_004582	RABGGTB	Rab geranylgeranyltransferase, beta subunit
chr6_+_41712907	1.394		MDFI	MyoD family inhibitor
chr1_+_181421984	1.375		LAMC2	laminin, gamma 2
chr13_-_98757634	1.314	NM_004951	GPR183	G protein-coupled receptor 183
chrX_+_65299352	1.305		HEPH	hephaestin
chr22_-_25344037	1.288		CRYBB1	crystallin, beta B1
chr11_+_384238	1.253		PKP3	plakophilin 3
chr1_-_159257595	1.252	NM_016946	F11R	F11 receptor
chr6_-_31812049	1.248		CLIC1	chloride intracellular channel 1
chr1_-_159257486	1.225		F11R	F11 receptor
chr20_-_581844	1.219	NM_080725	SRXN1	sulfiredoxin 1
chr19_-_48976852	1.201		KCNN4	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr3_-_172070641	1.176	NM_001099645	RPL22L1	ribosomal protein L22-like 1
chrX_+_65299157	1.155	NM_138737	HEPH	hephaestin
chr17_+_27795633	1.155		PSMD11	proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr6_-_31812072	1.153		CLIC1	chloride intracellular channel 1
chr3_+_154035425	1.151	NM_002563	P2RY1	purinergic receptor P2Y, G-protein coupled, 1
chr20_+_33223434	1.134	NM_006404	PROCR	protein C receptor, endothelial
chr17_+_27795598	1.126		PSMD11	proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr3_+_70131572	1.121
chr7_+_111850367	1.118	NM_001007245 NM_001197080	IFRD1	interferon-related developmental regulator 1
chr22_+_21370394	1.103		IGL@	immunoglobulin lambda locus
chr9_-_34652629	1.098	NM_006664	CCL27	chemokine (C-C motif) ligand 27
chr6_+_44302973	1.084		SLC29A1	solute carrier family 29 (nucleoside transporters), member 1
chr12_-_37585602	1.083	NM_153634	CPNE8	copine VIII
chr17_-_43254132	1.080	NM_145798	OSBPL7	oxysterol binding protein-like 7
chr17_+_27795635	1.079		PSMD11	proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr1_-_203916160	1.078		SLC45A3	solute carrier family 45, member 3
chr6_-_31812251	1.075		CLIC1	chloride intracellular channel 1
chr1_+_12046020	1.073	NM_001243	TNFRSF8	tumor necrosis factor receptor superfamily, member 8
chr4_-_174687104	1.069		HAND2	heart and neural crest derivatives expressed 2
chr6_-_31812260	1.067		CLIC1	chloride intracellular channel 1
chr6_-_31812214	1.064		CLIC1	chloride intracellular channel 1
chr4_-_977163	1.058	NM_022042 NM_134425 NM_213613	SLC26A1	solute carrier family 26 (sulfate transporter), member 1
chr11_-_14498443	1.056		PSMA1	proteasome (prosome, macropain) subunit, alpha type, 1
chr17_+_27795632	1.049		PSMD11	proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr11_+_67107641	1.046	NM_000852	GSTP1	glutathione S-transferase pi 1
chr22_+_18388656	1.041		C22orf25	chromosome 22 open reading frame 25
chr7_+_142205266	1.040
chr10_-_76538859	1.034	NM_001007271 NM_001007272 NM_001007273	DUSP13	dual specificity phosphatase 13
chr1_-_157313179	1.029	NM_004833	AIM2	absent in melanoma 2
chr7_-_150352484	1.029	NM_173681	ATG9B	ATG9 autophagy related 9 homolog B (S. cerevisiae)
chr9_-_35744271	1.022	NM_001044264	MSMP	microseminoprotein, prostate associated
chr17_+_27795645	1.008		PSMD11	proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr6_-_31812283	1.007		CLIC1	chloride intracellular channel 1
chr4_-_139382672	0.999	NM_014331	SLC7A11	solute carrier family 7, (cationic amino acid transporter, y+ system) member 11
chr6_-_31812266	0.997		CLIC1	chloride intracellular channel 1
chr6_-_31812297	0.992	NM_001288	CLIC1	chloride intracellular channel 1
chr1_+_89763030	0.992		LRRC8B	leucine rich repeat containing 8 family, member B
chr8_-_42742729	0.990	NM_004198	CHRNA6	cholinergic receptor, nicotinic, alpha 6
chr6_-_30792830	0.990		MDC1	mediator of DNA-damage checkpoint 1
chr11_-_14498462	0.989	NM_001143937 NM_002786	PSMA1	proteasome (prosome, macropain) subunit, alpha type, 1
chr16_-_87570716	0.987	NM_005187	CBFA2T3	core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr6_-_35996794	0.986		SRPK1	SRSF protein kinase 1
chr10_-_21502993	0.976		NEBL	nebulette
chr17_-_26665194	0.966		EVI2B	ecotropic viral integration site 2B
chr18_+_9875722	0.965	NM_001098529 NM_032243	TXNDC2	thioredoxin domain containing 2 (spermatozoa)
chrX_-_39921525	0.964	NM_001123383 NM_001123384	BCOR	BCL6 corepressor
chr1_+_45250503	0.958		UROD	uroporphyrinogen decarboxylase
chrX_+_12903145	0.953	NM_021109 NM_183049	TMSB4X TMSL3	thymosin beta 4, X-linked thymosin-like 3
chr6_+_1556543	0.937		FOXC1	forkhead box C1
chr17_-_26665213	0.932		EVI2B	ecotropic viral integration site 2B
chr6_+_44322764	0.925	NM_007355	HSP90AB1	heat shock protein 90kDa alpha (cytosolic), class B member 1
chr9_+_139292094	0.910	NM_017723	C9orf167	chromosome 9 open reading frame 167
chr6_-_31853027	0.899	NM_025258	C6orf27	chromosome 6 open reading frame 27
chr2_-_85494639	0.896		CAPG	capping protein (actin filament), gelsolin-like
chr17_-_26665144	0.896		EVI2B	ecotropic viral integration site 2B
chrX_+_69314060	0.895	NM_198512	DGAT2L6	diacylglycerol O-acyltransferase 2-like 6
chr2_-_85494664	0.895		CAPG	capping protein (actin filament), gelsolin-like
chr17_-_35975227	0.891	NM_001838	CCR7	chemokine (C-C motif) receptor 7
chr16_+_28413421	0.889	NM_018690	APOBR	apolipoprotein B receptor
chr11_+_67107852	0.885		GSTP1	glutathione S-transferase pi 1
chr7_-_102772304	0.877	NM_001129887 NM_014377	DNAJC2	DnaJ (Hsp40) homolog, subfamily C, member 2
chr1_+_181422016	0.876		LAMC2	laminin, gamma 2
chr17_-_31231421	0.876	NM_002985	CCL5	chemokine (C-C motif) ligand 5
chr6_+_32229278	0.875	NM_138717	PPT2	palmitoyl-protein thioesterase 2
chr17_+_27795607	0.869	NM_002815	PSMD11	proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr1_-_223683141	0.863	NM_194442	LBR	lamin B receptor
chr1_-_45045543	0.861	NM_001013632	TCTEX1D4	Tctex1 domain containing 4
chr19_-_48977247	0.853	NM_002250	KCNN4	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr1_+_181421796	0.848	NM_005562 NM_018891	LAMC2	laminin, gamma 2
chr19_-_4510713	0.848		SEMA6B	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
chr12_-_53099269	0.848		ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr9_+_130231027	0.844		CERCAM	cerebral endothelial cell adhesion molecule
chr17_-_43254117	0.842		OSBPL7	oxysterol binding protein-like 7
chr22_-_17846711	0.836		UFD1L	ubiquitin fusion degradation 1 like (yeast)
chr1_-_6474346	0.831	NM_020631	PLEKHG5	pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr11_+_128069165	0.829		FLI1	Friend leukemia virus integration 1
chr4_-_77163609	0.829	NM_001565	CXCL10	chemokine (C-X-C motif) ligand 10
chr6_+_44322831	0.828		HSP90AB1	heat shock protein 90kDa alpha (cytosolic), class B member 1
chrX_+_153423652	0.823	NM_001099856	IKBKG	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chr11_+_10434056	0.819	NM_001025390	AMPD3	adenosine monophosphate deaminase 3
chr2_-_144806508	0.819	NM_001164629	GTDC1	glycosyltransferase-like domain containing 1
chr2_-_144806498	0.817		GTDC1	glycosyltransferase-like domain containing 1
chr6_+_32229599	0.817	NM_005155	PPT2-EGFL8 PPT2	PPT2-EGFL8 read-through transcript palmitoyl-protein thioesterase 2
chr22_+_43451600	0.816		PRR5	proline rich 5 (renal)
chr4_+_22608252	0.804
chr9_-_126217510	0.804	NM_002799	PSMB7	proteasome (prosome, macropain) subunit, beta type, 7
chr1_-_205272619	0.798	NM_001083924 NM_023938	C1orf116	chromosome 1 open reading frame 116
chr22_+_21393107	0.794		IGLJ3	immunoglobulin lambda joining 3
chr22_+_21495273	0.792
chr12_-_101115677	0.787	NM_002674	PMCH	pro-melanin-concentrating hormone
chr11_+_128068982	0.784	NM_002017	FLI1	Friend leukemia virus integration 1
chr12_-_46439127	0.782	NM_001098531	RAPGEF3	Rap guanine nucleotide exchange factor (GEF) 3
chr12_-_51585004	0.781	NM_002273	KRT8	keratin 8
chr12_-_55316350	0.780	NM_013449	BAZ2A	bromodomain adjacent to zinc finger domain, 2A
chr4_-_145159889	0.779	NM_002100	GYPB	glycophorin B (MNS blood group)
chr19_+_10388448	0.776		PDE4A	phosphodiesterase 4A, cAMP-specific
chr4_+_88076418	0.760
chr22_+_21079355	0.757
chr11_-_65424434	0.746		FOSL1	FOS-like antigen 1
chr11_+_128069203	0.745		FLI1	Friend leukemia virus integration 1
chr11_+_62405736	0.739		SLC3A2	solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2
chr12_-_53099203	0.736		ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr6_-_35996867	0.735		SRPK1	SRSF protein kinase 1
chr2_+_87536174	0.728		NCRNA00152	non-protein coding RNA 152
chr11_+_62405801	0.720		SLC3A2	solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2
chr12_-_53099277	0.719	NM_002205	ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr11_-_65424436	0.715	NM_005438	FOSL1	FOS-like antigen 1
chr11_-_6633427	0.713	NM_003737	DCHS1	dachsous 1 (Drosophila)
chrX_-_152938528	0.712	NM_001025242 NM_001025243 NM_001569	IRAK1	interleukin-1 receptor-associated kinase 1
chr1_+_148747208	0.711		ECM1	extracellular matrix protein 1
chr11_-_65424385	0.710		FOSL1	FOS-like antigen 1
chrX_-_152938441	0.706		IRAK1	interleukin-1 receptor-associated kinase 1
chr4_+_170817787	0.705		CLCN3	chloride channel 3
chr22_-_17846621	0.700		UFD1L	ubiquitin fusion degradation 1 like (yeast)
chr17_-_77474597	0.699	NM_032711	MAFG	v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)
chr1_+_148747110	0.696	NM_004425 NM_022664	ECM1	extracellular matrix protein 1
chr3_+_161877640	0.692	NM_025047	ARL14	ADP-ribosylation factor-like 14
chr11_-_8982107	0.691	NM_020645	NRIP3	nuclear receptor interacting protein 3
chr17_+_22823151	0.690	NM_014238	KSR1	kinase suppressor of ras 1
chr17_-_26665220	0.689	NM_006495	EVI2B	ecotropic viral integration site 2B
chr1_-_52117021	0.689	NM_001101662 NM_002525	NRD1	nardilysin (N-arginine dibasic convertase)
chr19_-_56260135	0.687	NM_015596	KLK13	kallikrein-related peptidase 13
chr1_-_94147537	0.676		GCLM	glutamate-cysteine ligase, modifier subunit
chr22_-_17846725	0.675	NM_001035247 NM_005659	UFD1L	ubiquitin fusion degradation 1 like (yeast)
chr22_+_43451351	0.675	NM_001017530 NM_001198721 NM_015366	PRR5	proline rich 5 (renal)
chr1_-_94147574	0.666	NM_002061	GCLM	glutamate-cysteine ligase, modifier subunit
chr12_-_55368323	0.663	NM_006601	PTGES3	prostaglandin E synthase 3 (cytosolic)
chr3_-_15814678	0.658	NM_001195098	ANKRD28	ankyrin repeat domain 28
chr2_+_87536106	0.651		NCRNA00152	non-protein coding RNA 152
chr20_+_35445350	0.641		SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
chr11_+_46358909	0.640	NM_001012334	MDK	midkine (neurite growth-promoting factor 2)
chr12_-_49897743	0.635		POU6F1	POU class 6 homeobox 1
chr7_+_130445394	0.632	NM_001145354	MKLN1	muskelin 1, intracellular mediator containing kelch motifs
chr16_+_88696172	0.630		FAM157C	family with sequence similarity 157, member C
chr22_+_21053972	0.625
chrX_-_15593074	0.624	NM_020665	TMEM27	transmembrane protein 27
chr12_+_7233025	0.620	NM_001131026	PEX5	peroxisomal biogenesis factor 5
chr14_+_22422270	0.616	NM_173527	REM2	RAS (RAD and GEM)-like GTP binding 2
chr14_+_62740878	0.615	NM_020663	RHOJ	ras homolog gene family, member J
chr17_+_44643067	0.610		ABI3	ABI family, member 3
chr6_-_31658044	0.607	NM_002341 NM_009588	LTB	lymphotoxin beta (TNF superfamily, member 3)
chr12_+_54808220	0.606	NM_001184796 NM_015292	ESYT1	extended synaptotagmin-like protein 1
chr11_-_102174032	0.604		MMP1	matrix metallopeptidase 1 (interstitial collagenase)
chr6_-_35996915	0.601	NM_003137	SRPK1	SRSF protein kinase 1
chr5_-_169657312	0.601		LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr6_-_30793436	0.598	NM_014641	MDC1	mediator of DNA-damage checkpoint 1
chr5_-_169657395	0.597	NM_005565	LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.33	4.82e-03	GO:0007165	signal transduction
1.64	7.65e-03	GO:0051246	regulation of protein metabolic process
1.30	8.04e-03	GO:0023052	signaling
4.46	1.02e-02	GO:0006521	regulation of cellular amino acid metabolic process
1.28	1.62e-02	GO:0051716	cellular response to stimulus
3.98	1.87e-02	GO:0033238	regulation of cellular amine metabolic process
1.56	4.26e-02	GO:0050790	regulation of catalytic activity
1.60	4.32e-02	GO:0042981	regulation of apoptosis

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
4.91	1.12e-05	GO:0000502	proteasome complex
6.37	2.18e-02	GO:0005839	proteasome core complex
6.06	3.11e-02	GO:0001533	cornified envelope

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
3.75	8.91e-03	GO:0004197	cysteine-type endopeptidase activity
6.06	4.80e-02	GO:0004298	threonine-type endopeptidase activity
6.06	4.80e-02	GO:0070003	threonine-type peptidase activity